IMIPRAMINE HYDROCHLORIDE Reviews (IMIPRAMINE HYDROCHLORIDE)

Average Rating: 3.5 (106 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

IMIPRAMINE HCL  (IMIPRAMINE HYDROCHLORIDE):  This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.   FDA Approval Date: 1990-06-05 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on IMIPRAMINE HYDROCHLORIDE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR IMIPRAMINE HYDRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  for depression F 76 10 years
10 1X day
6/6/2015
 3  incontinance Constipation Some times get a little dizzy. M 76 30 days
5/27/2009
 1  mild depression and restless leg s dry mouth, dizzyness, can hardly urinate, bad taste in mouth, destroys sex life, severe loss of memory lasting about 2 hours resulting in trip to emergency room W/EKG, BRAIN SCAN, BLOOD WORK< all checked out normal.ER Doctor said this is a dangerous drug. Constipation. I also had bad head shocks a couple times a week, usually in the evening. I stoped this medication after taking it for about three months at 50 mg each night. I tappered off by dropping to 25mg for about a week and then to 12mg for a coupled af days stopping about a week ago. I feel much better. Some side effects are still with me but think in a week or so they should be gone. On the plus side it cured, while taking it, my restless leg syndrome and dryed up a post nasel drip that i've had for a long time and all signs of my mild depression. But the side effects we're not worth it. IF nessessery I'll try something else. M 73 90 days
7/11/2009
 5  Depression Taken for 20 years F 70 20 years
25mg 1X day
11/28/2010
 5  SEVERE LEG PAIN FROM NERVE IN BACK THIS MEDICINE STOPS THE PAIN CYCLE OF LEG NERVE PAIN & EVENTUALLY EASES SHARP PAIN DURING THE DAY. IT ACTUALLY SAVED MY LIFE BECAUSE THE PAIN WAS SO SEVERE. A DOCTOR IN LAS VEGAS PUT ME ON IMPARMINE I HAVE A LITTLE PAIN BUT NOT SERIOUS LIKE BEFORE I CAN FUNCTION ALL DAY WITH OUT MUCH TROUBLE THE MEDICINE LELAXES THE LEGS & STOPS THE PAIN NIGHTLY I WOULD RECOMEND ANYONE SUFFERING FROM SEVERE NERVE PAIN IN THE LEGS DUE TO A BACK INJURY BE PUT ON THIS MEDICINE IT IS VERY VAULABLE TO STOP THE PAIN CYCLE & FUNCTION THE NEXT DAY F 69 10 years
50 1X day
6/4/2011
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 5  Anxiety in response to panic Side effects only in first few weeks. ( IBS symptoms on and off in first year or so. Back in 1969 I was given LSD and had panicked on the drug. It left shocked up and had depersonalization / derealization for several months. I was subject to return bouts every so many years and felt like I could not be free of the fear of the panic and depersonalization. Then in 1986 science finally caught up with me. Started Impramine in fall of 1986 and within 3 months was a different person. I had to work up to high dose of 300 mg. Changed my life... fear of return of anxiety disappeared. On it now for 32 years and doing great.. Gave me my life back. M 67 32 years
300
7/3/2018
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 1  urinary incontinence doctor prescribed 50 mg per day, with no gradual introduction of drug; noticed immediately increased agitation; anxiety; dry mouth; bitter taste in mouth; impulsive behavior; suicidal thoughts; memory loss; ended up in emergency room for suicidal rant, worsened by drinking alcohol F 67 3.5 weeks
25 mg 2X day
3/18/2012
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 5  Migraines None Helps control vascular headaches. Reduced occurrences of headaches from one per week to less than three per year. I periodically try to reduce dosage to 50 mg per day, but eventually the headaches begin to return. 75 mg per day dosage controls the headaches without additional medication. M 66 24 years
25 mg 3X day
4/13/2010
 4  panic attacks and agoraphobia initially dry mouth, hard stools, some tremors in one arm. chew gum or suck on a candy with dry mouth, and stool softener works well when needed. just live with the tremor. my father took imipramine before me for 30+ years, and i have taken it for 33 years. my dad went off it due to his skin getting very dark after years of use. his skin lightened after going off the medication and switching to zoloft. i have used the meds for panic disorder and agoraphobia. i have consulted with psychiatrists over the years to determine if there is a better med. all the docs have said stick with what works, and i am doing so. M 63 33 years
150 1X day
9/19/2010
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 4  Overactive bladder I sleep around 3 hours then I'm awake. Dry mouth,head shakes mildly causing neck pain,constipation,leg twitching. I believe that if I was prescribed a lower dose these side effects might go away. F 63 3 weeks
25mg
11/2/2015
 1  Overactive bladder constipation, terrible morning depression - I could hardly get out of bed I was taking IMIPRAMINE HCL for overactive bladder issues. Having had depression for a long time I figured it might help since it is also used as an antidepressant. In preparation for some surgery I stopped taking the IMIPRAMINE HCL and within a week of stopping it I noticed that I no longer was waking up really depressed and not wanting to get out of bed. I started just waking up "normally" and didn't fear the morning anymore. M 63 365 days
75 1X day
8/18/2013
 1  Post Prostactomy incontinence Headaches, stomach cramps, constipation, muscle cramps, insomnia and indigestion. 50mg dose reduced to 25mg some improvement but for what little improvrmrnt in incontinence there was the side effects proved to be more detrimental than its benefits. I've flushed the remainder of my 90 day supply. M 63 6 days
6/18/2006
 5  Mild Depression I'll have five minutes of dry mouth; doesn't matter. I had been on 25mg a day for a few weeks and had a scary episode with urinary blockage. Then after I took it for a couple of months where I felt happy, I suddenly stopped and was hit with a Major panic attack. I am now taking 10mg and may stop. I Hate taking drugs. I feel like I'm chained to them. But it really works great for me, even in very low doses. I guess I should just live with mild depression and get little enjoyment from anything. F 62 14 days
10/25/2006
 4  Too many Nightime trips to bathroom vivid, sometimes crazy dreams sure seems to work M 62 2 days
75 mg 1X day
5/10/2013
Email
 1  post prostatectomy Had the opposite effect of increasing rather than decreasing incontinence M 62 6 days
8/10/2006
 5  Panic Disorder Dry mouth I was having severe panic attacks and this medication saved my life. It worked very well for me. I took it for about 3 years after my divorce. Since then I only need it when in a very stressful situation. F 61 25 years
12/9/2008
 5  anxiety or panic blurred vision; dry mouth only at first; possible weight gain of 25 lbs. I only take 10mg at bedtime but if I miss 2 doses I have a major panic attack. Hate being on a drug. Stops all panic/anxiety when I take it. F 60 2 years
6/26/2004
 1  Depression Used to take tofrinal- with imipramine it causes insomnia- tofrinal let me great great sleep. Ask pharmacy how much brand tofrinal would be and they told me $500- what a scam. F 60 2 days
10mg
7/8/2017
 5  Depression Dry mouth. I have to take Biotene to stop it Absolutely wonderful drug. I have been depressed all my life. Started on imipramine at 27. Always gave me big orgasms and all anxiety, social phobia went away. Weaned myself off and tried the new Ssri's. None of them worked. They stopped the depression but ALL caused insomnia and loss of libido, not to mention not being able to orgasm. SSRI's will kill you sleep and your sex life. I hate them. Doctors push for you to go on them but that's only because of the kickbacks they get. I will never take them again you may be less depressed but your relationship and sleep will suffer. Not worth it in my book. I went back onI imprimine at 55 and there was no weight gain, depression, and anxiety. I slept as soon as I hit the pillow. My sex life is wonderful and orgasms have returned normally with the added bonus of them being big. Lucky me😀 Take what works for you. F 58 30 years
150 1X day
2/20/2018
Email
 5  insomnia A Dry mouth makes me thirsty often, but that also helps me remember to drink more water. If take none, I sleep from 11pm until 3-4am. I can take 50mg and wake up about 5am or take 75mg to wake up 6:30am or take 100 MG and sleep in until 7 or 8am. M 57 17 years
5/16/2007
  

IMIPRAMINE HCL  (IMIPRAMINE HYDROCHLORIDE):  This medication is used to treat depression. It is also used with other therapies for the treatment of nighttime bed-wetting (enuresis) in children. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.   FDA Approval Date: 1990-06-05 (Sources: U.S. Centers for Medicare Services, FDA)

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