Drug Ratings for RESTASIS

Average Rating: 2.3 (109 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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    Charts & graphs: Reviews Summary for RESTASIS  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR RESTASISCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 3  Dry eyes Very puffy eyes, mainly in the "bag" area; still red; still scratchy (like I have sand in my eyes); light sensitivity to the point that I wear sunglasses inside my house. However, before Restasis, my symptoms were even worse. Severe redness, severe pain, severe light sensitivity. I feel like I've been crying 24/7 (the puffiness). I'm a widow, so I date on occasion. Now, I turn down invitations because I look and feel so bad. I wish there was something else I could use. F 67 4 months
.05% 2X D
12/8/2014
Email
 3  Dry eyes Severe chronic headaches, including sinus, eye , ear, and neck pain. Pressure and tighness around face and behind eyes. Itchy and sometime sticky sensations in and around eyes. Restasis seems to relieve my dry eyes problem at times, but after many years of complaining of all these symptoms to my doctors and not receiving answers, then now reading similar complaints of others, I am now more than convinced that my symptoms all in relation to my usage of Restasis. F 58 10 years
12/6/2014

 2  dry eyes My eyes started itching, pain in my eyes, the skin around my eyes got very dry. Blurred vision. Stop taking it waiting for doctor advice. F 53 30 days
2X D
12/1/2014

 1  dry eyes due to Sjogren's syndrome I experienced severe headaches, especially behind my eyes and in my ears, very puffy eyes, excessive mucous, difficulty breathing, an oral thrush that did not respond to multiple courses of medication. The side effects were gradual. Chest tightness and difficulty breathing was the clue that it was related to Restasis since I had the same symptoms from the oral tablet for dry mouth F 66 12 days
0.4 ml 2X D
11/26/2014
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 3  Uveitis dull headache in sinus area, feeling of pressure behind eyes. Undetermined at this time, will continue for a week or more, or until another possible side affect. F 64 3 days
1 2X D
11/23/2014
Email
 1   Lip problems causing dryness and three episodes of severe lip sweating, and swelling to the point of taking steroids to calm it down. Also severe neck pain. I'm going back to natural tears for dryness. I was on Restasis for a month and finally figured out that my problems were caused by the drug. F 66 30 days
2X D
11/21/2014

 2  Dry eyes swollen, itchy and red around upper eyelashes Was taking Restasis over a yr ago. I stopped taking it as I felt like it was doing anything, but then realized my eyes did get very dry again. Just started back up on it and my upper eyelash area is itchy, swollen and red mostly on left eye. Don't remember having these symptoms when I started on it before. F 45 5 days
2X D
11/16/2014

 3  chronic dry eyes Brief burning at first. After a few days my eyes were clear, no longer irritated and red. They looked and felt normal again. However I developed sudden, severe headache and neck pain. Also had high spike in my bp with no previous diagnosis of HTN. Scarey and uncomfortable. It is 10 days after stopping the restasis and I still have headaches and high bp. I have to take a bp med for now........this is the second time I have tried to use restasis in the past year with the same terrible side effects.....it took 4 mos for them to go away last time. I was told it would be unlikely to experience problems with bp because the cyclosporin was opthalmic and not IV.....well,ha; it did cause high blood pressure for me.........too bad because it helped my eyes. F 3 weeks
1 gtt q 12 1X D
11/15/2014

 4  dry eyes M 43
.05 1X D
10/23/2014
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History
 2   It seems that my dry eye is getting worse. I am wondering whether to trust my sense about that. After reading your comments, I am thinking I should trust it. I am thinking about using Hydro Eye which is a supplement that is opthamologist created and tested for dry eye. It contains Omega's and other anti-inflammatories. No known side effects and in testing it did bring relief. F 64 14 days
2X D
9/13/2014
Email
 4  severe dry eye/possible graves If you truly have dry eye this product should work for you-most of the time. If I didn't have it I would be in so much pain! Restasis keeps me level. It varies day to day, as to whether or not I am faithful in using. 12 hrs apart and weather also plays a roll. I do have headaches, tooth pain, and ear pain. My DR's tell me there is nothing wrong with my ears. But recently had 2 ear infections in which I have not had one since I was a child. I have pain behind the eye ball and tired burning red eyes if they are over worked from straining to read. Cannot read or look at computer for very long without pain, and I have pretty good vision 20/40. All I know after all the doctors I've seen, without restasis I would be in big trouble!!!!! The rest will come in time. Don't give up until you get an answer F 52 3 years
0.05
9/3/2014
Email
 1  Dry Eye Eye, head, gum and ear pressure pain on left side. Burning in eyes and redness of eyes. I have been using Restasis for over 8 years off and on. It worked miracles in the beginning. I stopped the medicine last summer, because I felt so great but my dry eye came on full force, worse than ever. Immediately I went back on the medicine, per doctor's order. He said my eyes were extremely dry and to not stop the restasis or I would have to get the plugs. So I started back up, but the pain got worse from that point on and never stopped. My left eye had blood in it, twice for an entire week. My eye doctor saw a little improvement but can't help with the pressure pain so he referred me out. I saw a million doctors and my dentist, they pass me around. I did CT Scans and MRI's, and nothing. Sinus and brain clear. No cavities. They think I am crazy. So now it's been over a year with this pain and my eyes feel dry as can be, I am confused and frustrated. Then, all of a sudden it hit me to google side effects, so I did but nothing appeared abnormal. I was looking on the restasis web site though. So tonight I googled restasis and headaches and boom, all these dissatisfied comments appeared with people having the same symptoms I have. I quit starting today. If I feel better in a month or two, I will know it's the restasis. I will keep everyone updated. F 8 years
2X D
9/2/2014
Email
 1  Dry eyes Worked well the first few months. I began taking this before my LASIK procedure. Now, all of a sudden, I am experiencing many side effects. I having itchy, burning eyes, blurred vision and rashes around my face. At first I thought maybe it was something else and that all of these symptoms were unrelated but it seems more apparent that it is from the restasis. I am going back to my OTC eye drops. These were expensive and should probably be removed from the market based on all the complaints. I am now concerned that this drug may have impacted my vision permanently. The FDA needs to investigate this drug further. F 29 6 months
30 MG
8/22/2014
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 3  dry eye Using as directed. 3rd week Seems a bit better. Each vile contains far more than 2 drops.. OK to save opened vile in refrigerator for next treatment ? expensive to waste M 72 2 weeks
0.05 2X D
7/25/2014

 1  Severe dry eyes Beet red eyes , headache started after day 3, swollen eye lids, painful burning eyes all day. Crust eyelids in am. F 65 6 days
7/25/2014

 1  Sjogren's Syndrome dry eyes I put one drop in one eye, only , because I am a professional artist, I need to see to work, and I feared the burning they warned me about. The initial burning was nothing. But, this is day three. I now have inflammation in that one eye, and all around it, a stiff neck, a fever, and a Headache. My visions is still blurry, and I can't work. All, from ONE drop. I wonder if doctors are being told to push this drug when they ignore the side effects. Let him try it!!! F 60 1 days
one vilae 2X D
7/17/2014
Email
 2  chronic dry eye, sjogrens burning after installed, extreme burning and soreness when I wake up, eye pain, stiff neck, headaches I went to my eye doctor today for pain behind my right eye and he scheduled me for an MRI to rule out ocular neuritis but said its probably my sinuses. My MRI is scheduled for a few days from now, but I don't think I need one now that I've read all of these awful things about restasis. I now know that my neck and eye pain are related to this. I am so done with it. How could my doctor not put two and two together? Also I have not noticed any improvement with my dry eyes. F 32 3 months
2X D
7/7/2014

 1  Dry eyes Constant nausea, sinus drainage, and runny nose. After stopping Restasis it took two months to get over nausea. I still have a runny nose after stopping Restasis 4 years ago. M 60 2 months
30 mg 2X D
7/3/2014

 1  Dry eyes migraine headache, sinus pressure, stomach upset, nausea, but I didn't have the burning side effect when applying the drops. Not taking it anymore didn't even help with my dry eyes. My eye dr. seems to disagree that it's the eye drops but I don't like this feeling so I'm am stopping it simply from reading other peoples exact same complaints. F 38 2 weeks
6/24/2014
Email
 3  Dry and burning eyes I am loosing my eye lashes. They have thinned out and I am not taking any new medicines. F 67 2 years
2X D
5/10/2014

 4  Dry eyes Head pain, head pressure, neck pain, migraine, ear pressure M 59 9 months
2X D
4/27/2014
Email
 1  chronic dry eye Severe headaches at the base of my neck. I have gone on and off this medication and can't handle the headaches. F 43 10 months
2X D
4/23/2014

 1  dry eye I used the eye drops for about a year and the dry eye was improved. However, I seemed to develop an intolerance and suffered rashes around the eyes, forehead and then legs. I think the side effects are not well publicized. No one mentioned the skin rashes around the eyes, eyelids, forehead, etc. The rashes spread to my legs and it took me a long time to connect this to the eye drops. I assumed it was a food allergy or environmental. But when I stopped Restasis and then started again it was clear that this drug was causing my problems. My eye doctor is not convinced, but I am. The drops appeared to help with my dry eye, but over time my body can't tolerate them. I take no other perscriptions. Consumer, beware! F 60 2 years
.05% 2X D
4/22/2014

 1  Dry eye burning, did not work Used this as prescribed BEFORE laser eye surgery. Had ZERO effect. My eyes were painfully dry after the surgery. Had tear duct plugs put in and haven't had problems since. The doctor that prescribed them is the same doctor that does the commercials. Seemed like a conflict of interest to me to start me on this regimen before hand. Wish I would have had the plugs instead. F 45 1 months
unsure 2X D
4/19/2014

 2  Medical dry eye and inflammation My eyes felt like they had a rim of fire over them all day. I developed a really bad tooth ache directly under the spot where I inserted the drops, mid eye. Not sure if tooth is infected but a month ago my xrays said my teeth were fine. I have osteopenia. The burning of my eyes were horrible and limited my beloved joy of reading. They made my eyes feel tired all day long. I did not do my night dose last night and the tooth pain is still there but much better and less aggravated. Seeing dentist today for another check up. The tooth pain was absolutely horrible. My face is swollen and a part of my lung hurts. Sodium Hydroxide is LYE people. Why would they cut an eye drop with lye? It is poisonous. F 60 14 days
.05 2X D
3/25/2014
Email
 1  Dry eye Restasis briefly improved my dry eye symptoms so I could wear my contact lenses again. The results were short-lived, though, and when my opthamologist inserted plugs in my tear ducts in addition to continued usage of the Restasis drops, the results were disasterous. Not only did the plugs become infected, but my vision has been permanently damaged. I can no longer wear contacts and my vision is far worse than it ever was. I regret ever using Restasis. I completely agree with others' comments about Restatis being doled out like candy with little regard for possible permanent side-effects and damage. F 56 6 months
30 MG 2X D
1/9/2014
Email
 1  Dry eyes My dry eyes did improve some but after 6 months I began to have skin problems but never related it to Restassis until now. Severe itching of lower legs, clusters of skin rashes that have small blisters that ooze and drain and itch severely, nasal drainage, severe episodes of sneezing, occasional eye pain, I checked with several professionals and they say the skin problems not related to Restassis but I think differently, & now after stopping the eye med I still battle the side effect although they have improved over time. Furthermore my vision changed considerably the point of needing prisms in my vision eye glass prescription. F 68 1 years
2 x a day
12/31/2013

 1  Dry eye Severe migraine headache, nausea, stiff neck I did not experience the burning sensation in my eyes, but the headache started on day two. Didn't immeidately associate it with restatis...but on day 4 I knew! Stopped immediately. F 62 4 days
2X D
12/10/2013
Email
 5  Sjogrens Sometimes burning, especially in worst eye. In the beginning it was severe burning but that became less over time. After 7 months I was able to cry with real tears and vision was better. Now, after 2.5 years I can drive at night. Occassional burning in exchange for better vision is a so worth it. Stick with it. F 69 2.5 years
one drop 2X D
12/8/2013

 1  Dry Eyes Made my eyes red and vision worse. It most definitely made my vision worse over time. I have stopped taking it. Would love to hear what natural treatments have worked for others M 55 1 years
2X D
11/24/2013
Email
 3  dry eyes 7 years after lasik I started using to improve my dry eyes in hopes to regain better vision without doing lasik again. I have had great results so far with the dry/red eye part, but not with the vision. My throat has become dry, but that is really the only negative so far. However, I do not know if it is related, but I just got my bloodwork back and my liver is the only thing that came back slightly off. Im not a big drinker and have no other health issues that would cause a liver problem, so Im suspecting this product is to blame and will stop using it immediately. I hope this is not permanent damage. F 31 1 months
1 drop 2x
10/27/2013
Email
 1  I'm not Just, problems with my eyes My eyes became blood red and I was unable to tolerte any light, as a matter of fact it was so bad that I could not even turn on the lamp in my bedroom. I had to wear sunglasses even when the sun was not out. And now after not using the drug for a few days, my eyes are not focusing clearly. I'm going to my doctors office today without an appointment. F 65 5 days
0.05% 2X D
9/19/2013
Email
 2  blepharitis/dry eye Headaches. Persistent upper respiratory, ear, sinus, and throat irritation leading to infection. Emotional changes. Anxiety and mild depression. Eye burning for 30-60 minutes after instilling the drops. Photosensitivity, I have tried restasis many times since it was approved and I always grow intolerant to it due to the side effects. All in all I have probably been on it for a total of two years on and off. Sometimes it seems to help my eyes a bit and other times it doesn't seem to be as effective. The side effects are always there though. Garbage drug for most people I think, I also think that the average ophthalmologist is full of baloney nowadays M 34 4 weeks
0.5 mg/ml 2X D
8/26/2013

 1  Dry eyes Eyes became red and painful. Symptoms continued for six months. Several years ago my ophthalmologist told me I had dry eyes ( I didn't know that) and suggested I try eye drops that would help. (I wasn't aware that Restasis was in clinical trial). After I tried them my eyes became red and painful, but I was encouraged to continue with them. After six months the symptoms were much worse and I told the doctor I would not continue using them. Even so, he wrote a new prescription which I told him I would not fill. My eyes have never recovered from the redness, burning and pain. Each time I see the Restasis commercial, I become angry that this devastating "medication" has not been removed from the market. F 83 6 months
1X D
8/19/2013

 3  Ocular Rosacea Dryness of eyes after using drops. Sharp eye pain occasionally, and breaking eye blood vessels causing pain and bloody eye. Bladder spasms, intolerable, blurred vision. Itching and crusty lower lids. Never had any burning or stinging. had 6 treatments of IPL, cash only since its not covered by insurance. Minimally improved. Extreme light sensitivity, and soreness of lids make it impossible to work at my computer job as a nurse. TV watch time is reduced due to eye soreness. Have only been able to start reading in the past few weeks. I am going to stop and see if bladder pain goes away. Have noticed emotional changes, depression and anxiety, even had a panic attack, seems to be getting worse the longer I use it. F 60 7 months
0.05% 2X D
7/6/2013
Email
 3  Sjögren's Syndrome I experience some burning and redness after instilling a drop of Restasis in my eyes. F 25 2 years
1 drop BID
7/4/2013

 2  Dry eye and Blepharitis Severe congestion, crippling headache, sneezing, fatigue, weakness....this medicine apparently weakens your immune system, I work a lot so I live a very healthy lifestyle in order to keep my immune system strong, I never get sick like this, it took me 2 weeks and three days off to realize it was Restasis, it did not help my eyes, it apparently takes months to help with eyes, I was hopeful about it but can't afford to be sick F 47 6 weeks
.5 mg
7/2/2013

 2  Dry eyes I developed rashes around my eyes, forehead and mouth. F 32 16 days
0.05 2X D
6/24/2013
Email
 1  Slight dry eyess reported to doctor Reported results indicate 1 in 10 will receive relief with this drug which takes at least three months to have a noticeable effect.. It is very expensive for such poor performance. I will not continue with this drug since there are much less expensive alternatives to treat my mild condition. This drug should not be recommended unless nothing else has worked! F 67 30 days
0.4ml 2X D
6/20/2013

 2  for dry eyes I am having a lot of head aces and sinus problems. I didn't know about all the side effects as I had not read the procure as the writing was so small. I came to this site and just found out the culprit of my problems. I am not going to use it any more. F 75
2X D
6/10/2013
Email
 1  Chronic dry eye Strong burning sensation was painful and lasted for up to 15-20 minutes I thought my eyes would ultimately adjust to using the drops, but they never did. The drops became so bothersome I discontinued them and switched to an OTC brand which works as well as, if not better than, Restasis without any of the side effects. I paid only a co-pay, so at least my useless expense was minimized. M 75 5 days
Standard 2X D
4/26/2013

 2  chronic dry eye Suspect sinus drainage and sore throat are result of restasis. Back of mouth (around back teeth and back of tongue) feel sore and irritated. Throat and nose feel restricted/ swollen. Symptoms improved after 1 week discontinuing drops. A second attempt a few weeks later resulted in same symptoms- sore throat actually worsened and dry mouth intensified. Negative outweighed positive for me. I really believe what I initially assumed to be allergy is in fact negative side effect of my eye drops! I have discontinued medication for the second time and I'm anxiously waiting for side effects to stop! F 32 1 years
2 x's per
4/17/2013

 1   Puffy and pain around eyes all day and red eyes just after administering. Some trouble focusing when moving eyes quickly, hard to focus under lower levels of light. Side effects are bad enough that I had to stop taking, and after 30 hours I'm still experiencing pretty severe pain that won't let up after advil even. I would have given this drug a negative rating if it were possible. The pain is far worse than the symptom (dry eyes). F 34 8 days
2X D
4/3/2013
Email
 2  blepharitis and dry eyes Sinus pain and swelling, sore throat, headache and upset stomach I did not have any stinging or red eyes when I put the drop in. It really helped my eyes, but I could not stand the sinus pain and sore throat so I had to stop it. F 63 14 days
0.4ML 2X D
3/22/2013
Email
 3  Severe dry eyes Sore throat, plugged ears, then sinus infection leading to bronchitis."Headache due to sinus pressure. Zithromycin was prescribed for bronchitis. My lungs are getting better (day 5) but now I realize the bronchitis was due to sinus drainage. Now, what's coming out of my nose is horrific!! I haven't been sick in YEARS. Not even a cold or the flu!! Suddenly, after taking this for a couple weeks, I have sinusitis, then bronchitis!! I'm going to continue but NOT tilt my head back as the directions suggest. If I don't get relief soon, I'm gonna have to ditch the restasis altogether. It's just not worth the pain. I have not tried the tear duct plugs. Opthamologist wanted to try restasis first. Bronchitits keeps me out of the gym. As it is, I feel extremely lethargic to the point of feeling "altered", like I'm drunk. No gym = dealbreaker!!! If this could work with out the painful sinuses, leading to bronchitis, then great! Otherwise, it isn't for me. Keeping me from the gym is absolutely unacceptable. F 50 30 days
2X D
3/16/2013

 1  Blepharitis/Dry eye My eyes burned and felt ultra scratchy long term, my eyes were much worse and I did not see the point in using more-horrible drug, that is fifty bucks down the drain and that the price with insurance and wiating a month for it to go through. F 55 2 days
2X D
2/22/2013

 1  Dry eye due to arthritis Severe headaches, sinus pain, bloody nose. I'm upset it took me two weeks to figure out that it was the Restasis that caused such sinus issues with me. I was in sever pain for two straight weeks. I thought I was getting a sinus infection (never had one before) especially since my nose was bleeding. Finally stopped the Restasis and WA-LA! Instant recovery! Since the Doc said Restasis wouldn't cause those side effects, I tried it one more time just one tube and guess what? Bloody nose! Never again! F 48 2 weeks
1 tube 1X D
2/3/2013
Email
 3  Chronic Dry Eye First time trying, I did not have steroids to get me through the first two weeks, so I quit after stinging was intolerable. New prescript and steroids, I have had no problem, but now after 6 months stinging has started upon administration. I will be checking my blood pressure and chlolesteral after reading other's effects. Before Restasis, I was using moisture drops 4 times a night, now maybe once a night. I feel fine during day, but no help with redness:( F 51 7 months
2X D
11/28/2012

 2  dry eye Not sure, stopped it after 4 days when I got a horrible cold. I never get colds. 4 days after using this stuff, I got a horrible sore throat, infected tonsils, sinus infection type symptoms, which then turned into a really bad cold. Three weeks later, I am still badly congested. I am very suspicious that this immunosuppressant medication may have made me vulnerable to catching this virus. I see one other similar comment. I may try the Restasis again if I ever feel better. Since I paid a fortune for it! F 61 4 days
.05% 2X D
10/27/2012

 3  severe dry eye burning and stinging, severe sensitivity t o light, but after 3 months the scratches on my eyeball are gone, and the side effects of restatis seem to have ended. Only thing is I have blood pressure issues,and am trying to figure out if it is the restatis. My eyes are so much better. but if the blood pressure issue is indeed related to restatis, I do'n't know what then. F 65 3 months
2X D
9/28/2012
Email
 3  Chronic dry eye My eyes burn for about 15 minutes after application. I have noticed a slight increase in my blood pressure, since beginning the medication. Also, after being on Restasis for about 2 months, I developed dry mouth at night. I am not sure if these two new symptoms are related to Restasis or not. Additionally, my eyelids are now red most of the time. Restasis has helped my dry eye to a degree. I no longer need a heavy ointment in my eyes while sleeping. Some days, I do not need additional eye drops, but other days I may use drops 4x per day. (I like Systane Ultra.) Prolonged computer use continues to dry my eyes. I am thinking about weaning myself off Restasis for a period of time, to see if my dry mouth, red lids and bp get back to normal. F 63 10 months
1 drop 2X D
4/1/2012

 1  Chronic Dry Eye During first year seemed like Restasis was helping a little. But even after plugs, OTC drops + Restasis my eyes became extremely sensitive to light, red, itchy, swollen lids and outer corners of eyes. I experimented by stopping Restasis for short bouts and my eyes showed improvement (I thought.) By-the-way I was using some OTC drops only & warm compresses in AM! But my DOC does NOT want me to stop these drops! Forget about it! It's my belief my eye pain/other is a direct result of Restastis use!!!!! F 62 4 years
2xDay
3/16/2012
Email
 5  Dry eye Very slight burning. This drug takes a long time to give you the desired result, however, the results when they kick in are impressive for my type of dry eye. My eye doc, said that my tears would evaporate every 3 seconds before whereas 12-14 is normal. They literall felt like sand paper before. Three months later, my tears now last 12 seconds before evaporating. The only problem is that you have to use them forever. F 43 1 years
2X D
2/22/2012
Email
 2  Sjogrens Syndrom/dry eyes This is my second attempt using Restasis hoping that this time I'd have improvement to my condition. The result this time is the same as the last: dryness/burning/constant blinking trying to get relief and when I used artificial tears with Restasis use the artificial tears had NO effect. I was better off just using the artificial tears without the Restasis. I have been chided by my opthamologist for not continuing Restasis, but if a medication worsens your condition why would anyone continue? I am sad that I am not one of those users that had beneficial results. F 69 3 months
2X D
2/17/2012
Email
 1  Dry eyes Made my dry eyes worse! F 39 6 months
1X D
2/3/2012

 1  Dry eye Eyed BURNED WAY worse than dry eye. They were also very red. Has more side effects than listed on package. M 42 4 days
.05 2X D
1/30/2012
Email
 2  dry eyes my eyes burn awful only relief is close my eyes really getting worse the longer I use them F 76 1 years
2X D
1/23/2012

 3  Sjogrens and Dry Eye Eyes feel better but have had spike in blood presure since starting. M 65 6 days
10mg 2X D
12/15/2011

 1  dry eye My eyes were so blurred. Sensitivity to bright light inside and outside. This medication was just awful. I just stop torturing myself. OTC lubricant eye drops from Target's $5.00 worked just as will with no side effects. F 55 22 days
2X D
12/3/2011
Email
 5  Ocular Rosacea None I have bottom punctal plugs as well as using the Restasis and warm packs on my eyes at bedtime. I haven't had any side effects in my eyes, they feel 100 times better. Still red all the time, but they were before starting Restasis. The only thing I'm wondering is if it's affected my cholestrol and triglycerides. They've been high since starting it and have now shot up really high. Cyclosporine can increase cholestrol but they claim Restatis doesn't get into the blood stream so I don't know. F 57 18 months
drops 2X D
11/7/2011
Email
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