SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)

Average Rating: 3.0 (158 Ratings)

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SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8


RATING  REASONSIDE EFFECTS FOR SAVELLACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Fibromyalgia Nausea, perspiration. I started with the titration pack, and the first week was tough on my stomach (felt nautious). I also felt sudden increases in heart rate and was sweating more. After about 3 weeks, the side effects went away, and so did most of the pain. This drug really works if you can stick with it. 42 8 weeks
11/9/2009
 4  fibromylgia pain, headache daily dry mouth, some constipation, more calm during the day, sleeping better at night. I believe my pain is being reduced little, by little. It is taking time and my Dr said to give it a chance of at least 2 weeks. my appetite seems to be reduced, has anyone experienced this??? 53 10 days
10/20/2009
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 4  Chronic Pain/Fibromyalgia Take it with food, and don't take it too late in the day. The titration pack was HELL on EARTH: nausea, dizziness, light sensitivity, feeling spacy, brain fog, nervous, jittery, light-headed, hot flashes. Thankfully it didn't last long. Now, it's just a bit of occasional nausea when I first wake up or if I take it without food. This does "take the edge off". I am still in significant pain, but it seems to rearrange things in my brain to bump up my pain tolerance. I've been able to stop using tramadol, which has been good for me. The pain, while not gone entirely, is more of an annoyance now. I seem to bounce back quicker from bad days also. 33 2 months
100 mg 1X day
3/8/2010
 4  Fibromyalgia Sweat really bad and anxiety attacks get worse in the beginning. Stopped it for a little while b/c I didn't think it was working so I stoped, but after a few weeks after stopping I realized it was working so I went back on. Stay on it if you feel it is working for you! 38 7 months
50 mg 1X day
5/27/2010
 4   0 days
8/26/2018
 3  Fibromyalgia - Severe Aches Extreme nausea, vomitting Switched to Savella from Lyrica due to over 50# weight gain in just 6 mos. & other adverse side effects. Nausea was mild w/ titration pack, but once regular dosage started, it got worse each day, ultimately resulting in vomitting about an hr. after each dose. Before the vomitting, I started to feel some relief from the deep, unrelenting aching & pain from the Fibro. Was so disappointed to have to discontinue it. 38 1.5 months
50 MG 2X day
3/12/2012
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 5  Fibro/Chronic Fatigue Side effects were mild nausea in first few weeks which has now gone. Worst was the strong heart beats or palpitations at night time. I have reduced dosage to 25mg 2 times daily and they have almost completely gone away. I love this medicine!!! I feel better now that I have in past 8 years. More energy, less brain fog, more endurance, less pain and stiffness. I am waking up at 7am and actually staying awake without having to take provigil. I actually did yard work and painting yesterday and the day before went on a long walk with my son and the dogs! Wow - never thought I would be able to do that again! This has been a miracle for me and I feel like I will be able to go back to work now and take care of my kids instead of being a lump just surviving!! F 52 4 weeks
50 2X day
11/17/2011
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 5  Chronic joint and muscle pain I started with 15 mg a day for a week and they 15 2X a day for a week 25 and 15 a day for a week. 25 and 25...25 50...50 and 50 a day. My dr had me start very slow because of the side effects and it helped. I would get nausea about 90 minutes to 2 hours after I took the pill and my heart raced and I could not sleep at all. I also noticed I was short of breath and if I did anything that took effort (mowing the yard) I could not catch my breath. It would take about 4 to 5 days for my body to get use to it and then it was time to does up again. I also lost about 5 pounds and my body felt flushed. After two months of the pill the my side effects are gone except the shortness of breath and I don’t require as much sleep as I did before. I do notice if I don’t eat at regular intervals I get nausea but if I eat it goes away. It took my pain away!!!!! I have been dealing with pain since I was a teenager and the last few years it has taken away my life. This medicine has been amazing even with the crapy side effects. It was scary as hell that first month with my heart racing and being short of breath ( I even went to the hospital one night because of chest pains) but it was worth it. What is one month of hell compared to a life that is pain free. I have more energy, I am happy, I am motivated to live again. I fixed my garage door after I replaced a leaky faucet all on the same day!!! I feel amazing. I am hoping with time the short of breath goes away. But even still, I am very satisfied F 32 2 months
50 2X day
5/29/2012
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 5  Fibro Fortunately NONE Having my first flare up since starting Savella. I'm scared to increase the dose because it may not work. Going back to the doctor tomorrow for help, none of the opioids worked this was the only drug that gave me any relief. F 48 4 months
50 mg 2X day
6/12/2012
 5  Chronic severe pain None. It relieved the constant unrelenting pain in my hands I had been experiencing for 6 years during the 1st wk of titration. Now pain in shoulders is bearable. F 52 3 months
100mg 2x/d
3/17/2012
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 5  Fibromyalgia some dizziness and slight weight loss in the first month, but have maintained a constant weight since. I've been extremely happy with Savella. I was first on cymbalta, which was ok, so I thought, then my Dr switched me to Savella, huge pain relief! I had a brief experience after about a year of taking it where my Dr switched me back to cymbalta, and the pain was unbearable! Within weeks of switching again to savella I was again pain free (minus the occasional flare-up). I've been on it a little over 3 years and am now able to again play tennis, volleyball, etc. and live my life without the pain and exhaustion :) F 29 3 years
50mg 2X day
7/13/2012
 5  fibromalgia None F 49 2 years
100 MG
7/18/2012
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 5  Fibromyalgia and + ANA Insomnia and felt like I couldn't lie still but that went away after about 3 weeks. I've been having problems since 14 so the insomnia was nothing new since I haven't slept thru a night in years because of my nawing joint pain and discomfort. I feel great after being in this for almost 3 months. I still have my days but that's a lot better than everyday being miserable. F 24 3 months
50mg 2xD
7/13/2012
 5  Chronic disabling pain Constipation, insomnia F 44 1 months
25mgs 2x
11/27/2012
 5  FMS, CFLIDS Began with clinical trials, so I have been on this medication a bit longer than those who started after FDA approval. It has changed my.tolerance of FM symptoms Significantły. If you are oink this medication and your insurance will not cover it, or no ins. Coverage at all contact Forest Pharmaceuticals in St. Louis, MO and talk with them about you're positive experiences with Savella and request their Patient Assistance Program. Some paperwork, easy, straight forward. Once approved the work I 90 Day increments and mail the meds to you prescribing doc where you will pick it up. A short tel call after that all required to continue, ard a new written Rx from the doctor. Please use the PAPS the pharmacy companies have just for this purpose. Please do not just stop taking something that is doing wonders for you. F 46 5 years
50 2X day
12/21/2012
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 5  Fibromyalgia FIRST WEEK: nausea, headache, nervousness. TAKE IT WITH FOOD - AND TAKE IT EARLY IN THE MORNING AND BY MID-DAY, OR IT WILL KEEP YOU AWAKE AT NIGHT. Give it at least two months for it to fully kick in & work properly. It isn't an instant fix - and it is nothing like Lyrica! Lyrica is poison. Savella gives real hope to fibro sufferers - if taken correctly! Savella works great. But the first week of side effects while titrating are a bit uncomfortable. After that, it's GREAT for energy, pain & brain fog, although it takes a couple months to see dramatic improvement. IGNORE any reviews from people who stopped taking it after the first week, because they most likely did not take it properly and just are not giving it a real chance to work. Savella is not a pain pill; it does not work instantly. Very important to remember: TAKE SAVELLA EARLY AND TAKE IT WITH FOOD; always take it with food. I take it at 5 a.m. & 2 a.m. (for 7 weeks now). If not taken correctly, it'll cause headaches/nausea. Don't give up; just give it at least two months to work. I take my doses halfway through my meals. If you take the second dose too late in the day, it will interfere with sleep. The second dose should be taken before 2 p.m. Unfortunately, doctors also aren't telling patients that because Savella is an SNRI, it SHOULD NOT be taken w/ other antidepressants or it'll make you sick (serotonin syndrome). Take it properly & give it a chance - because Savella helps A LOT for fibro sufferers! Wonderful for pain, energy & fibro fog. F 38 7 weeks
6/16/2009
 5  Fibromyalgia, depression None. This has helped me TREMENDOUSLY with my fibromyalgia pain and depression. I haven't felt this good since before I had my two children. My doctor said this has been used for decades over in Europe for as a treatment for depression. Good luck! F 32 60 days
6/15/2009
 5  Taking Savella for fibromyalgia It is helping the muscle and joint pain better than anything else ever has. It's almost like I don't have fibro. Still have some fatigue, though. Drugs.com has a drug interaction check, and there are many meds that can't be taken with Savella-- including Ultram. If you are taking it, please do yourself a favor and check for interactions. F 2 weeks
7/9/2009
 5  fibromyalgia headache, nausea, hot flashes if you continue through side effects for some of us it will work, quality of life better than in many many moons am definitely an advocate F 55
10/21/2009
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 5  Fibromyalgia A little hyper at first, heart palpations, hot flashes, sweating The side effects seemed heavy the first few days, but disappeared completely after a week. Once in a while I will get a sweat for no reason, but its rare. It took away a lot of my pain, although nothing has ever done anything 100 percent for fibro. Out of all that I have tried, Savella is the best, with the least side effects. I felt more mobile and less pain throughout my body. I am on 50 mg now, but I will ask for an increase to 100 mg, the max per day, because I feel it working real well. Since there are almost no side effects after the first few days, I can tolerate Savella real well. I just hope that 100 mg will not give me side effects. This new drug has potential. Beautiful. F 37 6 weeks
10/20/2009
  

SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

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