PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32


RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  BPD,BP,Major Depressive Disorder loss of appetite, upset stomach/nausea This drug is the best. It has worked better than any other drug for me. I have trie them all. I used to be a frequent flyer to the hospital. This drug has kept me out. Along with it I take Abilify because my depression is pretty bad sometimes. F 52 18 years
100 1X day
1/24/2016
Email
 2  Anxiety Anxiety, weight gain, high blood pressure This Medicine was amazing at first and helped with my panic attacks but after 15 years it’s made them worse and completely stopped working. I have gained 25 lbs being on this medication and now have to be on high blood pressure meds F 40 15 years
100 1X day
1/16/2023
Email
 4  Clinical depression Constant heartburn Came off it for a few days and withdrawal symptoms were terrible F 74 10 years
100 MG 1X day
11/29/2020
Email
 3  Depression Was Great at first then went down hill after years of taking it. When I first started it was great. helped me and I was Happy. As time went on I started getting headaches almost every other day. Felt sick at night and my sex drive has gone down to nothing, If you miss a dose you cant function because of the severe head spins and delayed vision. But If you take your missed dose the symtoms are gone in about 30 minutes. I believe its time for me to have the doctor switch me to something else. I was fine for the first few years and it gets worse as time goes on. F 45 8 years
50mg 1X day
2/11/2013
 5  Depression and anxiety Idc. It saved my life! If you get a mouth swab, it will tell you what meds your body will process most effectively. I have tried all antidep, but my body responds the best to SNRIs. F 45 7 years
100 mg
1/13/2015
 4  GAD Panic Disorder Moderate loss of libido. Excessive sweating. Slight weight gain. Occasionally forgetfulness. SNRI that worked the best for me and still feels effective to some extent after 7 years. M 25 7 years
100 1X day
12/10/2020
 1  Depression, Anxiety Brain fog, very slow reaction time, very dizzy, couldnt drive, couldnt think or make decisions, lactation and weightloss, no rem sleep, supressed my emotions, night sweats, memory loss, its like someone stuffed cottonwool in my head. I wasnt monitored on it. The doctor didnt make sure I was getting help from a therapist while taking it which should be mandatory. He even suggested I go out and drink like a normal 22 year old girl. You CAN NOT DRINK ON THIS DRUG! Worst years of my life. Also to get off it you have to spend a long time vomiting, sweating, shivering and feeling like your having a heart attack. Dont give this to young women! You might as well roofie them and send them out into the world. This is a really dangerous drug. Since being off it its like a curtain has lifted and I can think, work and my memory has come back. It also started wearing off after 4 years. F 28 7 years
100 1X day
11/9/2020
 5  Major Depressive Illness - Changes in libido plus ED (these have since gone) - No other side-effects Without doubt PRISTIQ changed my life - and I am grateful for a chance to say so on this forum. Best I do it in point form: - over 30 years of prior major depressive episodes (suicidal thoughts and attempts, multiple hospital admissions, electric shock treatments etc etc) - started on 50mg once-daily, March, 2009 when depressed and suicidal (again) - felt unbelievable signs of decrease in depression and suicidal tendencies after only one week - continued feeling better and better - breakthrough depression at six months - dose increased to 100mg daily - stayed on 100mg for 12 months - asked Doc to reduce me back to 50mg daily as a 'test' because of changes in libido and ED (erectile dysfunction) - have remained on 50mg daily since - NO depression - NO suicidal thoughts - just one happy and grateful person at age 57 (and I fathered a new addition to our family in 2013 - a healthy daughter born in 2014!) - life is so good today - I feel like one of the 'normal' people P.S. as for libido and erection problems - I wanted to 'test' the 50mg dose again and whether libido/ED side-effects would settle down (they did) - BUT - and it's a huge "but" - I was willing to stay on 100mg if need be and live with unpredictable libido and erection issues - my wife and I wanted me to stay ALIVE much more than have an alive penis! M 57 6 years
50mg 1X day
10/27/2015
Email
 5  anxiety/depression slight low sodium levels. initial high blood pressure but that went back to normal. slightly lower sex drive i also take this with wellbutrin xl 150mg 1/day. the combo works great for me. tried switching from pristiq to see if sodium levels would go back to normal, but within a month had terrible anxiety/panic attacks, insomnia, and anger - went back on Pristiq and was back to myself within a week. Pristiq definitely works and the benefits outweigh the side effect. Also, Pristiq is weight neutral for me. F 43 6 years
50 1X day
5/21/2014
 4  Server depression/anxiety Low libido, forgetfulness. Brain zaps, light headed and headaches, nausea, if I miss a dose. I started with 50mgs the Doctor put the dosage up once the symptoms eased to 100mgs. Each year on the effectiveness would wear off so up another 50mgs till I was on 200mgs. Spent the last year on 150mgs starting to wean off. Last month on 100mgs with feeling agitated, mood swings headaches & the last few days I have spent crying from emotional meltdowns. Didn't make it to work today. Had to talk to anyone about what I am trying to do when it makes me burst into tears. Not to mention keeping my depression secret from people outside a small amount of close family and friends. Wondering how I can get this done with out having to explain it to my daughter's (10 & 8) F 46 6 years
200mg
2/6/2017
Email
 4  Major Depressive Disorder First few days felt drowsy, dry mouth. immediate lessening of anxiety and improvement in mood and ability to control emotions. My body has a history of gradually requiring more dosage over years. Was on Effexor, Ciprimil before they didn't work anymore. I enjoy a good quality of life thanks to Pristiq. F 46 6 years
400 1X day
2/13/2017
 4  depression Reduced libido When I am on this drug, I feel great, and occasionally I even skip a day, but if I skip more than a day, I spiral down almost immediately. This drug has worked wonders for me. I consider it much better than Paxil, which really zonked me out. M 69 6 years
50 1X day
2/22/2017
 4  Depression and anxiety Definitely helps steady my moods but there are scary side effects while drinking alcohol. These include black outs, memory loss, acting out of character, dropping to ground without cause, blurred vision and slurred speech. I've always thought that it was just me being drunk, but now I'm certain it's the combination of this drug and alcohol that does it. F 31 6 years
50
1/1/2013
 3  Depression / Anxiety While on the drug: initially, I noticed no side effects - I had been on Effexor and was switched to Pristiq because of insurance issues. The last year and a half I felt flat, didn't care about anything. I'm currently in the process of weaning off, and THOSE side effects are pretty bad. Nausea, vertigo, night sweats, bizarre dreams, angry about everything. This company seriously should be ashamed of itself when it comes to people weaning off. They know you will experience withdrawal and make nothing lower than 50mg, and tell people not to cut the pills because it is extended release. Pfizer, I'm talking to you! You need to make some step down pills! F 41 6 years
100 1X day
4/26/2016
 3  Depression If I miss a dose, I feel completely hopeless. It is the closest I've ever came to suicide. If I miss a dose, I feel completely hopeless. It is the closest I've ever came to suicide. F 54 6 years
50 mg 1X day
3/23/2022
 1  depression/anxiety While taking the drug it seemed OK. It definitely was not a cure all and recently I have been switching my approach to more counseling and weaning myself off of all meds. The weaning from Pristiq has been TERRIBLE. I have had extreme dizziness, memory loss, sensitivity to light, extreme irritability and anxiety. I was told by my MD that it caused the low blood pressure and light headedness that caused my to lose conscienceness and wreck my car. I advise extreme caution tapering off of this drug. I have not found many medical professionals who prescribe Pristiq. The Cleveland Clinic advised me that they do not prescribe it. I do not recommend this anti-depressant. I've been on many of them and have never experienced the side effects when stopping any of the others like I have Pristiq. I think it is a very dangerous drug. F 31 6 years
100 1X day
4/3/2012
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 5  Depression None. Great medicine for me. I would recommend it to anyone depressed to try even though it is pricey. F 61 5 years
50mg
2/29/2016
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 5  Depression Wanting to sing and dance. F 46 5 years
50mg.
4/26/2014
 5  cyclothymia (mild mood swings) Head rushes when getting up. Went away after 2wks. Life saver. THE MAGIC PILL for me at 50mg. I went up to 100mg one time, and did not like it at that dose it made me feel cloudy. F 46 5 years
50 1X day
4/28/2014
Email
 5  anxiety/depression/panic disorder at the beginning had nausea and flu like symptoms.brain zaps,insomnia Once the initial side effects wore off, it made me a new person. I became more tolerant and happy in my life. Midway I felt it had decreased in its effectiveness doc upped it to 100mg and I had severe reaction that landed me in the ER. went back to 50 mg and all went back to perfect. I take it at around 3 am and it puts me in a deep sleep with vivid dreams but wake up feeling ok. F 50 5 years
50mg 1X day
9/28/2014
  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

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