WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression, anxiety, irritability constipation, frequent urination My doctor recently added Wellbutrin 150mg to my daily 200 mg of zoloft. I have been on it for two weeks and have noticed my mood is better, however I am becoming extremely constipated. I also had a bad headache for the first week but that went away. Frequent urination is a problem as well, I drink at least 64 oz. of water daily and am going to the bathroom on average once an hour. I would like to stay on the Wellbutrin but not sure if I can tolerate these side effects long term. F 44 2 weeks
10/12/2008
 5  depression none yet I just started my "generic" wellburtin xl today 75mg for 14days the 150mg 1xper day after that. Ive been on wellbutrin in the past but didnt take it long enough to see if it really works. I will post again after a few days F 34 1 days
10/9/2008
 3  SAD sight focus problems, no other side effects This is my first med and my first week on it (150mg). I feel almost no side effects and the med does not work for now. Dr said it'll start working in 2-3 weeks so I'm waiting. F 28 7 days
10/9/2008
 4  counter SSRI sexual side effects I tried SSRIs for anexiety and loved all the effects other than the loss of sex drive. I started Wellbutrin to offset this, but liked it enought to taper off the SSRIs entirely. Only side effects with Wellbutrin XL 300mg are slight, tolerable jitters and insomnia. Tried Effexor and it worked great at first then diminished over a few monts. Next was Lexapro, which works very well for mood and anexiety however the sexual side effects were intolerable. I simply had zero sex drive. So far I like the Buproprion. Don't be cheap and get the generic. The lower dose of the generic caused more side effects than double the dosage of the name brand. M 33 2 weeks
10/3/2008
 2  depression Muscle pain, swelling of extremities,pressure headace, neurological symptoms and muscle loss Wellbutrin was like a wonder drug for my depression until I increased my dose and experienced muscle pain and swelling as well as severe pressure type headache. My reaction seemed to trigger my illness. I had the swelling the pain and the muscle twitching. I was a vibrant young women and am now on disability and have significant muscle loss that Dr.'s can't explain as well as multiple sclerosis symptoms with a normal mri. The Dr.'s are baffled. I can't say for sure if wellbutrin caused this but the reaction seemed to trigger this. Please contact me if you have heard of anything like this or if anyone has sustained long term health effects as a result of wellbutrin use. F 32 2 years
9/30/2008
 4  SAD, depression slight tremors, memory problems There is a definate difference between name brand Wellbutrin XL and Buprion. I was taking buprion last year twice a day, generic form. This fall, I asked for name brand, and there is a definate difference. No headaches this time at all. Side effects don't seem have as bad as when I started out last year. My memory is bad, tremors and muscle twitching is the only bad side effects I have with this. Overall, pretty pleased with the XL so far. I'll give it a couple months and let you know more! F 43 3 weeks
9/29/2008
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 5  Depression shaky feeling, weight loss, libido increased tremendously This medicine greatly helped my depression. Feel like I can make it through the day in a good mood. One positive side effect: It's made my sex drive shoot throught the roof! Don't have a sexual partner right now. I Masterbate alot to ease the sexual tension GREAT DRUG! F 44 4 months
9/25/2008
 2  Increase sex drive Extreme social anxiety, tremors, insomnia & restlessness, increased urination, decreased sex drive, absolutely no apetite I took wellbutrin for 2 weeks to help increase sex drive from SSRI discontinuation. This drug did nothing but make me feel very paranoid, anxious and not hungry. I would only recommend this drug to people who can't have SSRI's or want to lose weight. If you suffer from any sort of anxiety, DO NOT TAKE THIS DRUG. M 21 2 weeks
9/24/2008
 3  depression insomnia, reckless behavior, extreme anger and hostility I took this drug few years ago for depression. I was on it for over 1.5 years. For the first couple of months I experienced insomnia and extreme hostility. Also, I would go shopping and spend a lot of money with out even thinking about it. Those side effects eventually went away and I was happy with the drug for over a year. I felt so good that I stopped taking it. I felt great for over a year on no medication. I eventually became depressed again and now I have been taking it for a few weeks. I am experiencing the exact same side effects this time around. I am just trying to get through it because I know that last time these effects disappeared after a period of time. It is hard though. I try to avoid people right now because I feel like a loose canon and I don't want to lose any friends during this phase. F 29 3 weeks
9/23/2008
 4  Depression Insomnia, loss of appetite, headaches, stomach pain, nausea, dizziness, nervousness, impatience, slowed thinking, forgetfullness I use 300mg of Wellbutrin and 300mg of Effexor. This does seem to be the perfect combination to beat back both the emotional and cognitive aspects of my depression. I would say that like most ADs it has a very dramatic lifting effect in the beginning which tapers off over time to a less noticeable and more manageable level.For example, the first few weeks saw me out of the bed at very early hours and compulsively doing housework. Now I just get a little lift in the morning that get me out of bed at a normal hour and I don't feel the need to be a workaholic all the time. I haven't had seriously negative thoughts for a long time, although occasionally I feel it isn't working as well as it should. However when I try to reduce the dosage of either drug, over time negative thoughts and slowed thinking takes over my mind gradually. I am happy with Wellbutrin, but i nearly gave up on it a couple times because of the bad side effects. But over a period of 6 months they gradually wore off. I do M 25 16 months
9/21/2008
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 3  Depression/Anxiety Restlessness, irritability, confusion, I can't seem to remember something I was just doing minutes ago, I feel like I am walking in a fog, and not quite all there. The insomnia is not as bad, went away after the first few days. Loss of appetite. Difficulty focusing and making simple decisions. Still having crying bouts. I have been on 150mg for exactly one week now. Can anyone out there please give me some encouragement with this drug. I have almost stopped it twice because of the side effects but since this is the 4th drug I have tried, I am pushing thru. Generally, I just feel out of it, spaced out, and not myself. Will this go away in time? I feel a little better I would say, since I am no longer crying all day, just at nights. Overall I have seen no improvement in the anxiety, but perhaps this too will improve with time. Anyone else have these feelings at first? and for those that did, did you stick it out and did it get better? I am at the point where I just really want to feel myself again, and have my life back. I have become really impatient and fearful of these medications since being on Paxil, Cipralex, Effexor, and now this one. I just really want it to work. Please feel free to email me. F 29 8 days
9/21/2008
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 5  Migraines and depression Weight Loss. Felt a little "high" at first but nothing too extreme. Weight loss at first but only about 15 pounds. I finally felt happy and I actually wanted to get up in the morning and do something. Didn't help migraines much but greatly improved my depression. Recently diagnosed with Fibromyalgia and tried to increase does to 450mg (up from 300mg) and it caused extreme anxiety and panic attacks so I decreased back to 300mg and I feel fine again. F 43 8 years
9/20/2008
 4  Depression Weight Loss, Tremors, Increased Heart Rate Wellbutrin XL 150 definitely does it's job of boosting your moods! In addition, it gives me the energy that I need to get through the day! I don't want to focus on all the bad side effects, because let's face it people, you're going to have side effects with ANY drug. Wellbutrin does speed the heart rate up, but use it to your advantage and get out and exercise! I'm a runner, so with me, it has leveled itself out over time. I lost 25 lbs off of Wellbutrin XL 150 in the first 6 months. It makes me not eat when I'm not hungry. I do however, have slight tremors in my hands, but it's nothing I can't live with! I have also tried the generic, and it is NOT the same. I went back into a state of depression in the 2 weeks I took the generic. I highly recommend Wellbutrin XL 150 but NOT the generic Buproprion. F 26 10 months
9/19/2008
 2  depression dry mouth, constipation, occassional agitation, muscle fatigue/pain, shortness of breath One symptom of my depression was frequently sleepiness, particularly in the afternoons, and the general feeling that I could never get enough sleep. Wellbutrin has helped in this respect, and given me more energy. I 've also lost almost twenty pounds, although this is not from loss of appetite (am as hungry as ever), but maybe because the alleviated depression has given me more energy and discipline to approach dieting. I plan to go off the medication soon, however, as three side-effects have become particularly troublesome. When I went up to 400 mg of Wellbutrin per day, I began getting constipated. I also experienced pronounced joint pain/muscle fatigue, and found myself frequently short of breath/easily winded. I should note that I am a vegetarian, and avid recreational cyclist, and constipation, muscle pain, and shortness of breath are problems I have ever experienced. I'm 47 years old, 6' 1", and weigh 174 lbs., so I'm in pretty good shape for my age. And I don't M 47 4 months
9/18/2008
 3  Depression Hair loss I have been on Wellbutrin XL for almost 2 months now. About 1 week after starting the Wellbutrin I experienced accelerated hair loss. My hair has been slowing thinning over the past 20 years, but it certainly got worse after starting Wellbutrin. I will stop taking the medication and hope my recently lost hair grows back. The benefits of Wellbutrin don't make up for the increased depression caused by this hair loss. I also experienced increased hair loss with Zoloft. I know the experts say that only a very small percentage of patients experience hair loss while taking Wellbutrin. In my opinion, people with normally thick hair won't notice if they're losing any hair. I think you have to lose about 50% of your hair before noticing any marked difference in thickness. It's people like me, who have thin hair to begin with, who notice the hair loss while on medication. F 41 2 months
9/13/2008
 2  GAD insomnia, disoriented I have been taking 40mg Celexa for about 3 years for anxiety, and just last week I added 150mg of Wellbutrin. So far, I can't say I really like it(I'm writing this at 3:00am). I'll still it out for a couple of weeks and then we'll see. F 40 4 days
8/30/2008
 5  depression began taking Wellbutrin XL on March 31, 2007 as a replacement for Lexapro which had made me gain 30 pounds in 2 yrs. The initial side effects were brain flashes from Lexapro withdrawal. The only Wellbutrin side effect was weight loss- about 3 lbs per week. Eventually, I lost 40 lbs in 3 months and then my weight stabilized. This has been a good side effect since it motivated me to return to regular exercise and better eating habits. Wellbutrin has been very good for me. It has greatly reduced my depression and anger. It also has enabled me to become more focused at work. I went from an under performer to an over performer. At my last review, my boss commented on the change and wondered why. I did not tell her it's Wellbutrin. My wife also knows that she does not have to worry about me becoming angry for irrational reasons. I recently tried a generic form of Wellbutrin XL manufactured by Anchen because the brand name was not available. I was quite apprehensive about doing so due to reports of generic wellbutrin being different than the brand. However, I cannot detect any difference in its effects. M 53 17 months
8/29/2008
 3  Depression Chest pain, anxiety, dry mouth, loss of appetite For the first week I Was put on wellbutrin xl 150mg a day and I felt better and had more energy and did not crave nicotine what so ever after the first week they put me right up to 300mg and the second day that night I had chest pain and anxiety, it is the next morning right now as I right this and i still have the chest pain(not as bad as last night). I went to the clinic last night and the doctor told me i had the classic symptoms of my dose being way too high for me so he put me back down to 150mg. I do think wellbutrin xl helps me just not at such a high dose lol F 26 9 days
8/25/2008
 4  Post partum depression Extreme weight loss, insomnia, racing heart I am soo thankful for Wellbutrin. I never got help for my post partum depression and five years later I went into a major depression. I lost a year of my life. 3 days after I started taking wellbutrin I started smiling again. i started exercising. Afgter a month I had lost forty pounds. i look like me again. For a whole year I thought about suicide everyday. I wasn't the wife and Mom that my family needed. My kids are more happy and my relationship with my husband has been rekindled. Just don't take this medication at night. I didn't sleep for a month before I figured out that was the cause. F 29 6 months
8/14/2008
 4  situational depression/anxitey hardly any side effects.. weight loss, dry mouth at the very beginning only I have been on it since February. The first few months, I had no appetite and did not crave anything sweet.. also had dry mouth. I was originally on 150 mg, then up'd to 300 mg, still with no side effects... I then started to feel better, so went back down to 150mg on my own.. (doc wasn't too happy). I then crashed and started to feel bad again, so went back up to 300mg. I have been back up on 300 mg for about 2 months now and feel good. My appetite is back, but i feel like i have not gained the 6 or 7 lbs back that i originally lost. I'm thinking it speeds up your metabolism or something, bc my eating is back to normal, but the weight hasn't come back.. Win, win, i guess... Last time i crashed, i wanted to be up'd to 450 but my doc would not do that.. I'm cruising on 300mg right now.. and feel good.. F 37 6 months
8/13/2008

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