There are 1748 ratings for the drug: CYMBALTA in the Askapatient database.

Key to ratings for cymbalta: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken and Dosage		Date Added
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4	Depression, Anxiety	Weight gain, nausea, fatigue, feeling very hot & sweating profusely, constipation, headaches, thinning hair	I tried Cymbalta as I had heard that it was weight neutral and I had gained a lot of weight on Prozac, Lexapro & Effexor. It has really helped with the depression and anxiety but am now finding that I feel 'flat' emotionally and am having more side effects. Find it very difficult to lose weight even on a low calorie eating plan. Intense sugar/salt cravings. Weird dreams. I want to go off the medication but my psychiatrist doesn't agree. The weight gain and exhaustion are more than I can take but I am so afraid of landing in a deep depression and becoming suicidal again.	F	59	3 years 90 1X D		8/31/2010 Email
4	Anxiety	Excessive sweating, tired during day, weight gain of almost 13 lbs.	Cymbalta helped my anxiety almost immediately and I am much calmer now. Sweating is really a problem though along with weight gain. Considering going off meds.	F	47	4 months 60mg 1X D		8/29/2010
5	Depression, anxiety, insomnia	First few months dramatic decrease in sex drive and ability to have orgasm and ejaculation. Worked like a truth drug telling people exactly what I thought about them and everything else but very calmly and to the point. Increased desire to consume alcohol.	No other side effects and the sex drive/performance issues leveled out to normal after a few months. The blatant honesty side effect was surprising at work, home, and with friends but was liberating for me personally. Way more social and easily engaged in conversation with friends and total strangers. Discontinuing this drug has been a big challenge for the past month. This is the worst side effect of all since life was really good while I was taking it.	M	47	1.5 years 30 mg 1X D		8/28/2010
3	Depression - extremely suicidal	Inabailty to orgasm, insomnia, migraine headaches, jaw clenching, feeling 'wired' and speedy.	I found the drug very effective at lifting my mood and removing depression. I also found it made me feel more empathetic and connected to people, something i had not felt for a very long time. I found that once the initial start up dose of 30mg was increased to 60 mg, I suffered from migraines for a period of time. Eventually these went away. Also i found it very difficult to orgasm. This actually became worse the longer I was on the medication, and in some ways the only way to have orgasm was to stop taking the medication for a day, then wait till the next day to have orgasm. I also began to find it really hard to sleep, and also felt too racy and speedy. I have recently stopped taking cymbalta - even though the +ve on mood and disposition were very good, I found not being able to orgasm, sleep etc were making me want to stop taking the drug. Since stopping, I definately am struggling again with mood, and disposition... I may try another type of anti_depressant... I'm not sure yet though.	M	35	5 days 60 1X D		8/28/2010 Email
4	Depression	Constipation, vivid dreams and restless sleep patterns	Overall this med helped me with my energy levels and fatigue. I know longer feel tired in the afternoons, I no longer cry at the drop of a hat and I feel alert and focused. Prior to taking this, I was a trembling, sappy mess who could not think about holding a job. Now I am on my second interview thanks to Cymbalta	F	44	40 days 60 1X D		8/27/2010
3	GAO	Nausea, dry mouth, loss of appetite	Has already started helping with my anxiety. Involved in very stressful situation last night and felt very calm throughout. I weighed myself and have already lost one pound in just 2 days from loss of appetite. It's the weekend though, so I'm concerned about the nausea during work hours.	M	39	3 days 30 1X D		8/22/2010 Email
3	Neuropathy pain & depression	Increased depression, lethargy, fatigue, sugar cravings, night sweats	Initially, I felt that my depression worsened- even though my nerve pain lessened. It has been a difficult summer so I questioned how much of it was the medication vs. situational depression. It is always important to look at the big picture and not jump to conclusions about what may/may not be a side effect. I was strongly encouraged to try to ride out the side effects, as a nurse, I know that these improve or disappate in time. The night sweats decreased, the fatigue continues- but I also work night shift and wonder if I am just getting burnt out. I initially started with 60mg, but intended to titrate off the medication, so I slowly reduced my doseage to 30mg- where I currently remain. I am feeling better and am beginning to feel like perhaps I should continue and see how things go. I also am on Wellbutrin for depression. I am not sexually active, but think if George Clooney showed up... I might not care much. I strongly encourage anyone trying this medication to not go off it without talking with your doctor about how to do so safely. Also, please give it a chance to work, there will likely be side effects to most medications you try- but your body needs a chance to adapt to it and this can take 2-4 wks. As I said, I am stablizing- it has helped my nerve pain, I am using the Neurontin I was on only once daily now for trigeminal nerve pain from a crushing blow. For now, my plan is to give it another month and see how I feel. If there is any weight gain wh	F	41	30 days 30mg 1X D		8/22/2010
5		Dry Mouth: Tolerable. Loose Stool: Also tolerable. Decreased Appetite: Tolerable and Grateful!	It's Day 4. I didn't realize I had GAD. I thought BEING ANXIOUS WAS NORMAL. In the past year, I've lost a family member, gotten engaged, moved to fiancee, lost two friendships, and have had two family members in the hospital 4 over 25 days with major medical life threatening problems. I have been to 7 doctor appts since April certain I have "a condition". My thoughts, every day, were centered around "when they find a diagnosis.." That thought process led to Sweating, Acting Out, and Severe TMJ with Bruxism. My Doctor prescribed Cymbalta for day and Xanax for night to deal with the teeth clenching. I already feel NORMAL. I can sit and focus on my job. I can now sit and focus on what family and friends are saying. My mind is quiet. AGAIN, I DIDN'T KNOW I HAD ANXIETY UNTIL I TOOK THIS CYMBALTA. I just thought I was a TYPE A, High Strung, Colorful Character. ALL I CAN SAY IS ...WHAT A RELIEF... Doc gave me 60mg for the next week. I am going to call him and tell him 30mg is just fine. GIVE IT A CHANCE.	F	43	4 days 30mg 1X D		8/21/2010 Email
4	fibromayalgia	runny nose,hot flashes, extreme sweating ,weight loss,gas,dry mouth,vaginal irritation,ejaculation problems	i went on cymbalta five weeks ago as a tryout.my doctor gave it to me to take together with amitripyline at nights.after the second dosage i felt a relief.the horrible pain was gone.my mind could focus properly,i felt energetic. i was happy. by the end of week number one i began to have dry mouth and i got an infection in my vagina.the doctor took me off it ,but the withdrawal was so bad with so much pain that he put me back on it.right now i am five weeks in and my life is a living hell. i am always thirsty,have a bad taste in my mouth ,sweating all the time, passing gas all over the place, i have had some weight loss, loss of appetite and my sex life is suffering. i also have internal body heat.i want to be free of this drug but it helped so well with the pain,and i don't want it back. withdrawal symtoms are worst. please if Dr.says cymbalta to you say no.it is like a satan.	F	26	5 weeks 60 mg 1X D		8/20/2010 Email
4	Depression/Fibromyalgia	Dry mouth, fatigue, dizziness and nausea for the first week	I'm very sensitive to medications and originally reacted very badly to a 30MG dose of Cymbalta. When I was switched to the smallest dose possible, I did much better. The physical side effects were the worst the first two weeks, but psychologically I felt a change from day one. It's not a miracle worker and does not take away all my pain, especially on a low dose, but it helps me mentally balance so that I can focus on healing and managing my pain. Forgetting a dose does have side effects like nausea and dizziness and a major brain fog, even on the lowest dose - don't forget doses and wean yourself off slowly if you're trying to quit! :)	F	20	6 months 20 MG 1X D		8/20/2010
3	Anxiety/Eating Disorder	Reduced anxiety, some weight loss, memory loss, confusion, nausea, decreased appetite	I told my doctor that I would not take anything that was linked to weight gain, and that i would do my own research to find out. After reading Cymbalta and no connection to weight gain I agreed to take it. At first I was happy with it. It has significantly reduced my anxiety to a level where I can now function, however after reading everyone elses comments, I'm begining to wonder whether my recent weight gain could be attributed to this drug. Overall, its done what it has meant to for me; reduced my crippling anxiety	F	26	4 weeks 60 1X D		8/19/2010 Email
1	Fibromyalgia/Back Pain	Excessive sweating/Hair thinning/Insomnia	I called Eli Lilly about the hair thinning since it is not listed as a side effect. Also, reported to the FDA. All online now, only takes a few minutes and includes prepaid postage. I am so tired of drugs that I try helping me with pain but then have such horrible side effects! The FDA needs to hear about it. Eli Lily stated that they don't have to report anything under 5%. Anyone else having hair loss problems as a side effect should also call the company and report it to the FDA.	F	48	4 months 40mg 1X D		8/19/2010
4	anxiety	dry mouth, sleepiness	started to not work as well after 4 years	M	52	4 years 90 1X D		8/18/2010
1	Severe depression	Four broken teeth due to grinding/clamping of my jaw. In June 2010 I suffered a detached retina and have very little vision in my right eye. Only now that i am starting to feel better have I realised that this drug may be responsilble for these side effects. now suffering from stomach cramps, constant nausea and insomnia whilst trying to come off this horrid drug.		F	44	18 months 60MG 1X D		8/17/2010
5	nueropathy after chemo; depession	constipation but helped w/ additional fiber; some weight gain	This drug helped the severe leg and muscle pain immediately! I was depressed and overwhelmed during my cancer treatments, and the 2nd round of chemo caused pain that prevented sleep - or any real rest. I feel so much better now, sleep easily, can focus at work,am happy and able to deal with my situation. Comparing how I feel now to a year ago is night & day. And, the weight gain is probably because I enjoy eating again. It's been amazing!	F	61	11 months 60mg 1X D		8/15/2010
4	Depression Fibromyalgia	at start dry mouth& metallic taste; started clinching jaws which causes headache, tooth and gum pain & neck pain.	The dry mouth is very insignificant compared to depression. For those people who do not understand why anyone would take these drugs with all the side effects YOU HAVE NEVER SUFFERED REAL DEPRESSION. It is necessary to find one with fewest side effects and everyone is different. What can you live with?? I am assuming the Cymbalta is the cause of the clinching. I had the same thing with Lexapro along with some other things.	M	68	2 months 1X D		8/15/2010
1	Chronic Pain	HAIR LOSS STARTED UP AFTER 5 MONTHS AND HAS BECOME A MAJOR PROBLEM. OTHER SYMPTOMS HAVE GOTTEN WORSE: SUGAR CRAVINGS, EXCESSIVE SWEATING, JITTERY/ANXIOUS	This drug worked wonders for my pain from Fibromyalgia and chronic pain that occured after surgery. It lifted my depressiona and make me a happier person-for 5 months. Then major side effects started occuring as stated. Also, the anxiety is now interfering with my life. Scared to come off of it because of the prior pain yet cannot handle these side effects. Every time I put my hand through my hair, I have a hand full of hair to throw out. Finding my hair everywhere. That is also very scary.	F	56	6 months 30mg 1X D		8/14/2010
4	Depression	Bad breath, Weight loss, Feel drauzy, Increased sexual lust, Cold sweats		F	24	2 months 30 1X D		8/13/2010
1	depression anxiety	Horrible sweating,feelings of tremendous heat.Numb and prickling hands,horrible taste in mouth.Feeling sick-headachy and nauseous all the time.Heart racing.Pounding all over.Can't sleep.Strange feelings that I can't describe.Mental confusion and loss of memory.	Cymbalta does control anxiety a lot,and depression to a very small extent,but I can't keep taking this drug due to awful side effects.	F	60	3 months 20-30mg 1X D		8/12/2010 Email
5	severe refractory depression	weight loss, anorexigenic, dry mouth (most notable the first few days), "speedy" feeling (dissipated after two days)	This medication literally saved my life. I've battled with PPD and major depression since first getting pregnant 4 years ago, which took a sharp turn for the worse within weeks after giving birth. I've tried every SSRI and SNRI on the market, with no (or negative) results. I finally gave up the search for an anti-depressant almost 2 years ago, and dealt with the resulting problems as they presented. I confessed to our family physician that I was experience severe bouts of anger (I went so far as to throw a lit cigarette at my husband the day before because he wouldn't "leave me alone) and I've never experienced anger like that before -- I am the most passive, peaceful person on the planet. My physician suggested depression, at which I baulked -- I figured it was anxiety, or stress, or just "life catching up with me." My physician smiled and told me to give it a try; at the very least, he said, it would help curb my anxiety and reduce the incidence of my panic attacks, something I've dealth with, unmedicated, since I was 8 years old. I took the prescription, but decided not to fill it. My husband, who is vehemently opposed to "mind-altering" medications, was the one who finally prompted me to try Cymbalta when he came across the prescription four days later. I was very hesitant, but I figured I'd take it once to appease him and be done with it. I took my first pill just before we went to bed that night, and within an hour, I noticed the first po	F	26	2 weeks 60 MG 1X D		8/11/2010 Email
2	Depression	Heart racing, vivid dreams and/or nightmares every single night, total loss of interest in sex, difficulty concentrating/focusing, weight gain/impossible to lose weight, and my head feels strange - hard to describe like sort of light-headedness. Also, tiredness and lack of motivation.	I was on lexapro for years and it worked just great - I am switching back. Cymbalta didn't even relieve my depression symptoms fully and I am not increasing my dosage because the side effects bother me.	F	36	4 months 30 MG 1X D		8/11/2010
5	Major Depression, PMDD, Anxiety	First Month: Insomnia, Constipation, Nausea, Exhaustion, Severe Withdrawal with missed dose. Side effects have relented a bit into the second month. This drug is horrible at first, but you HAVE to stick with it. I know it's hard.	You CANNOT miss a dose or you will be sicker than you've ever been in withdrawal. I can't even begin to describe how awful it is. Constipation was really bad in first month, now it comes and goes. I've increased my fiber through my diet -lots of fresh fruit and veggies, that seems to help. Nausea is pretty much gone, and my sleep pattern seems to be normalizing now. For the first few weeks I was on it I had intense dreams, some of them unpleasant. If I was able to finally get to sleep, the sleep was not good. That has also subsided. This drug has saved my life. After 2 months I am feeling mentally normal again. I am slowly getting my life back from severe depression. This is a hard drug to stick with, I was REALLY sick at first. It really does get better. Just DON'T miss a dose. 24 hours after missing a dose the withdrawal is really intense and you are really sick until about 3 hours after you take a dose. I've suffered with PMDD for years, and I always know when I am about to start when the PMDD starts up. I can get so depressed right before my period that I would be downright suicidal, cry uncontrollably, have passive aggressive tendencies, and that is gone. This month I did not even know I was about to start! I don't know how I will ever get off this drug when the time comes, because of the withdrawals. For now it has drastically changed my life for the better, so I will just have to cross that bridge when I get there.	F	33	60 days 30 mg 1X D		8/10/2010
3	Anxiety/ Minor Depression	In the beginning, felt very tired, yawning all the time, drymouth, dizziness and some eyesight blurriness primarily at night when driving. Now, i have been gaining weight (coming up on 10lbs in the last 2-3 months) and my diet and exercise routine has not changed. And it seems like the meds are not working like they use to.	My doctor has pretty much said to ride it out and see if the symptoms continue. I just refilled yet another prescription but after this month is up, I will probably look into something else. My anxiety is milder than before, but I've been taking an additional anxiety med to take the last bit edge off to a tolerable level. And my depression is about the same as it was in the very beginning.	F	28	7 months 60MG 1X D		8/10/2010
3	Depression, Anxiety	Hair loss, Weight Gain, Severe tiredness / exhaustion	At first this medication worked really well for depression and anxiety. Then I gained 20 pounds, had insatiable sugar cravings and I increasingly overslept. The tiredness is what is finally compelling me to get off this medication (although the weight gain is also contributing to this). I can't stand to sleep any more. I have spent most of the past year in bed. I am sleeping away my thirties. The sleeping and the weight gain are making me more depressed then I already was. Also I feel emotionally flat on Cymbalta. I haven't cried in over a year. I don't think I could if I wanted to. In short, I really needed this medication when I started taking it. Now that I've stabilized the side effects outweigh any benefits.	F	32	1 years 60 MG 1X D		8/9/2010
1	Pain	Slept continually night and day for 4 days. 2 hrs after taking Cymbalta I started to tremble and shake.	4 days was not enough to see any pain moderation and no drug is worth being giving up life and being confined to bed.	F	63	4 days 30mg 1X D		8/9/2010 Email
2	depersonalization and depression	Sleep disturbances (both insomnia and drowsiness). Feeling medicated and numb. More of that good old sexual dysfuntion and complete loss of libido!	I tried this medication hoping it would be effective since I had good results for a time on Effexor (which of course is also an SNRI). Unfortunately it wasn't a good fit for me at all. More side effects than with any other antidepressant (and I've been on a slew of them).	M	42	6 weeks 60 1X D		8/6/2010
3	major depression, severe anxiety	So far I feel kind of high and it seems like I can feel my brain if that makes sense. I am not sleepy at all - I feel wide awake. I have some nausea and loss of appetite.	I was very surprised to feel so much from the very first dose. I am glad to feel anything because that means I dont have to wait 30 days for it to do what it is supposed to do. I am only on day 3 but went looking for feedback on what other people feel taking this medicine. It looks like it affects everyone differently from what I'm reading here. I'm hoping to experience the 'weight loss' side effect. Not liking the sound of constipation or hair loss though. I'm glad to know what to look for based on everyone's experiences blogged here. I have been on SSRI's before but never an SNRI. I think this medicine is making it easier to concentrate.	F	34	3 days 30 1X D		8/5/2010
2	Mild anxiety	I'd say it had a mild effect on my anxiety; thoughts still mostly there, but butterflies not. MANY mild side effects: 1) Libido actually increased a bit, probably due to lower anxiety about things, though orgasms more elusive. Didn't bother me too much; usually had one "the next time" 2) Constipation, controllable with Fibercon. 3) Insomnia, despite taking first in AM. 4) Slightly blurred distance vision 4) Pretty sure my thinking isn't quite as reliable 5) Weight gain already. Given all the above, for only marginal benefit, I'm stopping.		M	46	3 months 60 1X D		8/2/2010
2	Back pain and sciatica	Major anxiety, shaking, very tense (especially neck muscles), a little nausea		M	49	7 days 30 mg 1X D		8/2/2010
2	Mastecomy Pain Syndrome, Neuropathy	Horrible Sweating, Memory Loss, Confusion, Loss of Libido, 10# Weight Gain	Cymbalta has helped my pain. It has also helped me get to the point of being in a better mood, having energy and being able to exercise. This has been huge for me. If only they could develop these pain drugs without the horrible side effects. I am now at the point of having to decide to stay with it or try to go off of it because the side effects I listed are wearing me down. I just don't want that terrible pain back.	F	51	8 months 20mg 1XD 1X D		8/2/2010
5	depression ocd	little tired, slow weight Gain.	I was on concerta for ADD when a counselor recommended Cymbalta. This med has really helped with my mood swings, my anxiety, and every other negative aspect of my personality. I am a little concerned about the weight gain but it may be due to the discontinuance of the Concerta.	M	43	15 days 60 mg 1X D		8/1/2010
4	Bipolar Depression	Jaw clenching,	I was hospitalized at Four Winds for three weeks for depression. They put me on cymbalta. It has definitely helped tremendously with depression. I am grateful for this medication.	M	20	3 months 60 mg 1X D		8/1/2010 Email
1	depression	35 lb weight gain, stomach upset almost since day one of taking it, no sex drive, blurred vision, dizziness, etc.	Decided to stop taking cymbalta and the withdrawals are HORRIBLE! I will never take this drug again and I will tell everyone who will listen to me not to take it. It is truly evil!!	F	52	2 years 60mg 1X D		8/1/2010
5	Neuralgia, Myofascial Pain Syndrome	nausea	Cymbalta is a wonder drug for me. I feel so much better on it, happier, able to do activities I'd given up on. The only side effect was nausea, but that was mitigated when I changed to taking it at night. I was on nortriptyline before which only took care of the shingles post herpetic neuralgia, but didn't touch the sacroiliac joints nerve pain that came up after a 3 level lumbar fusion, both are permanent nerve damage. The Cymbalta took care of both excruciating types of nerve pain. I also have myofascial fascial pain syndrome with trigger points in all major muscle groups. The Cymbalta hasn't touched the major trigger point problems but it has resolved the smaller triggerpoints and fascial pain such as on my ribs and chest. I still have the bad dry mouth that we thought was from the nortriptyline. But with the dry eyes and skin dryness, we are beginning to think that's sjogren's syndrome.	F	56	5 months 30 1X D		7/31/2010 Email
1	depression	i feel high, my vision is blurred, i can't think or concentrate, i am always sleepy, but can't really sleep, dilated pupils, glassy eyes, diarrhea but sandy looking, sudden heat and pins on my back and head when I'm nervous. i bad taste in my mouth, dry mouth, constantly drinking though, and finally i have absolutly no appetite, even when i do eat it tastes like chemicals.	this has been horrible! i wake up at all times in the night and then i can't get back to bed and then i wake up really early take a shower and then suddenly tired so i have to go back to sleep, and even after that sleep i have to take another one later in the day. the sleeping has been a vicious cycle. so i stopped taking this medication as of today, and i am so happy that i will not have to experience this any more.	F	19	5 days 20 mg 1X D		7/31/2010
2	depression/anxiety	sadness,nauseau		M	38	3 months 60 1X D		7/29/2010
5	depression and pain from accident	no bad ones, this was wonderful, except for cost	I had to go off Cymbalta due to the expense. I have been off for 2 weeks and still have weepy, angry moments and the pain has returned. I hope I will be able to get help from something cheaper.	F	63	3 years 60 1X D		7/28/2010
1	I wasn't. I don't take drugs	I don't see why all these healthy young people are on these dangerous drugs. Do you believe all the TV pitches about drugs? Are you that dumb? Being a little depressed or "down" is part of life. Find distractions, excercise, visit friends, do anything, but stay away from drugs. They will make you worse, not better. Our country is over prescribed on useless meds. Break away! Think for yourself!! Don't just pop a pill and think it will make things better.	Sucks big time, but so do other drugs.	F	67	0 days 0 1X D		7/28/2010
2	anxiety	nausea,weight loss, sweating regularly (like hot flashes, but more frequent and uncomfortable), inability to have an orgasm	It was given to me to help with chronic back pain and anxiety. I do not like the feelings I am having. Feel a little zombie like, sweating (I normally did not) and do like the sexual side effects.	F	54	3 weeks 30/then 60 1X D		7/25/2010
1	depression/fibro	loss of interest in everything, NO libido, WEIGHT GAIN(even though they say only 1% of people gain weight. If I forget to take, I get "brain zaps".	I am tired of feeling like a fat zombie, no emotions either way, I am in the process of "withdrawing" from the medicine. I have read and have been told I will feel much better in a few weeks and like a "New" person	F	44	3 years 60 1X D		7/20/2010
4		Dizziness, lethargy, zero libido, nausea, massive weight gain, memory loss and impairment.	Whilst this drug helped me to begin with I feel that the longer I am on it the worse I am becoming in regards to my memory, lethargy, libido and now anger is also becoming an issue. I have gained some serious weight with this medication and this is leading to deeper depression and embarrassment, I would not advise this medication as a long term solution but rather a short term helper.	F	35	15 months 60mg 1X D		7/19/2010 Email
4	anxiety/moderate long term depressi	Headache and slightly hungover feeling if I forget to take it.	Took zoloft for 10 years, when that stopped working, I tried Lexapro and then Effexor. Neither of which made a dent in my depression. Cymbalta slowly pulled me out of the darkness and I've developed a sex drive for the first time in 15 years. I am so very thankful that it works for me and believe that if you are on the edge of giving up, it is definitely worth trying.	F	37	1 years 100 1X D		7/19/2010 Email
4	Moderate Depression, Severe Anxiety	Night sweats, constipation, taking longer to climax during sexual intercourse	I am glad that I started Cymbalta before I came to this site. I have only been on Cymbalta for 10 days but I am already starting to feel so much better...I've gone years and years being depressed, sometimes severe sometimes moderately. The disheartening thing is that the people who are most likely to post on sites like this are the few that have had bad side effects. However, remember that everyone is different and out of ALL those taking this medication only 20-30% end up with severe side effects if any at all. Every person physiologically is different and processes meds such as Cymbalta differently. There is a balance...there are many who are taking this medication and have not had any side effects at all and even the ones that have, it has been worth the side effects. I am hoping that my experience with this med continues and that it gets more effective as time goes on.	M	32	10 days 60 1X D		7/18/2010
5	depression and anxiety	initially, had stomach pains and some tiredness. some sexual side effects, constipation.	this is my second pass at cymbalta. the first time, the side effects were more severe and included brain zaps and a feeling of being amped up. now, after being on it for 4 months, this second time is so much better. i don't have any of the brain zaps anymore and i don't get tired or to amped up. i take it in the early evening as i find this works best for my system. i have had two long lasting side effects. the first is constipation. i now take benefiber three times a day and this really helps out tremendously. just with each meal. benefiber comes in "to go" packages so it's easy when i go traveling or eat out. the second side effect is the sexual one. although i do have the desire and can achieve an erection, it is difficult for me to orgasm. i used to be able to do it easily but now, it takes real effort and all the planets have to be aligned, if you catch my drift. also, the amount of semen that comes out has diminished. i try to reach orgasm, but if i don't, i am not discouraged, and maybe that is the cymbalta working to not make me depressed, i'm not sure. PLEASE, if you are a male and have had similar experiences, please contact me, i'd like to discuss this with someone who has the same side effects as me and find out possible solutions, etc. overall, i really do like cymbalta and don't see myself getting off of it any time soon.	M	41	3 months 30mg 1X D		7/16/2010 Email
3	Major depression	I get brain buzzes, headaches, and cannot sleep. Major Depression has been helped but still have anxiety and panic attacks and days when I feel just simply not motivated. Not sure on this one		M	42	6 months 120 1X D		7/13/2010
3	depression/anxiety	stomach pain, loose stools/diarrhea	This medication helped my depression somewhat but the constant upset stomach has been too much for me.	F	30	120 days 60 1X D		7/12/2010
3	depression	at first none felt great after approx i week got this foggy feeling, always tired, have a not care to do any thing attitude	this is my second time on this first time quit cold turkey not to may problems other than those silly brain zaps. this will be my second and last time taking after one day i feel 100% better hopefully tommorw will be the same	M	43	30 days 30mg 1X D		7/10/2010 Email
4	Major Depression	Initially; dizziness, brain zaps, weight loss, nausea. These dissipated after a couple of months. Now I have night sweats and my body temperature has increased. My weight has stablised and I am seven pounds heavier than I used to be, but I have a decreased appetite. As others have said, the withdrawals happen very quickly - I get pins and needles in my face and tongue (how bizzarre!) within hours of missing a dose.	I have found that this has helped my depression and anxiety very much. I no longer have suicidal thoughts (which i had lived with for fifteen years), I no longer am extremely anxious and negative. It has not helped my hypersomnia - I can still sleep for up to 14 hours a day. Am looking at changing my meds (I also take a small dose of Lamictal every day) as I am very unmotivated and slightly depressed at the moment but I think t could be to do with my life circumstances which aren't great right now.	F	34	2.5 years 60 1X D		7/7/2010
4	depression/fatigue due to MS	Daytime sleepiness. Primary Care Physician suggested taking it at night. I began taking Cymbalta late in the afternoon and there seems to be improvement.	I have MS and the fatigue/depression for the past year have been at times almost unbearable. Neurologist didn't seem to care about my quality of life. I finally was able to get my primary care doctor to prescribe Cymbalta.	F	68	18 days 60 mg 1X D		7/2/2010 Email
2	Fibromyalgia	INITIAL: Nausea, constipation, diarrhea, dry mouth, dizziness MONTH TWO: All of the above PLUS,headache, decreased libido, back pain, night sweats, hot flashes, flushing, heartburn, insomnia, constant yawning, blurred vision. MONTH THREE: All of the above,PLUS, profuse sweating, stiff neck, joint stiffness, weight gain (10 lbs. in 6 weeks), difficulty passing urine, extreme itching, difficulty reaching orgasm, cold sores, pins & needles in hands and feet. WITHDRAWAL SYMPTOMS: All of the above,PLUS,restless legs, chills, crying, fatigue & restlessness at the same time, eyes aching & itching, heart palpitations, multiple intense violent nightmares throughout the night, feeling drugged or hung over, flu-like symptoms, extreme flatulence, difficulty swallowing, difficulty concentrating or focusing, extreme thirst, pressure in the head, shortness of breath, itching & ringing in ears, loss of balance.	Initial side effects were worth living with because my pain had decreased substantially. As time went on the side effects increased & became worse. Then i developed an itch in my breast that became so intense it began to blister. I experienced 3 weeks of hell going thru tests (mammogram, ultrasound, MRI & biopsy) to confirm it wasn't inflammatory breast cancer. I finally made the connection when reading another patient's comments with the same symptoms. I have been weaning off this drug over 3 weeks and still feel horrible. I wish I had found this site earlier. I would never have taken this terrible drug.	F	52	3 months 60 MG 1X D		6/28/2010 Email
5	Severe Depression	Dry skin, dry/cracked lips, hair loss decreased libido with difficult climax.	I was falling deep into depression and was suicidal after a separation and immediately noticed a change within the first few hours after taking my first dose. This medication not only gave me my life back but showed me what I had been missing my whole life. I have several food allergies and many of them affect my mood. I was very unsure at first but now I realize it was the best thing I could have done at the time. without it i could have hurt myself or someone else. Be very careful with taking doses regularly because the side affects are severe. I was unable to take mine for days and was very frightened (something very wrong)the whole time without it especially when trying to sleep. This is a powerful drug and not for everyone but in my case it worked like a miracle. My family is in health care and I was raised learning about medicine. My feelings are that this drug is a double sided sword. The side affects can be controlled if you are careful and smart. If you will be gone TAKE EXTRA WITH YOU and have more just in case you run out. My lips were dry for a year after taking it. Sometimes less is better I have read.	M	32	6 months 25mg /50 2X D		6/27/2010
4	Depression & nerve pain	Constipation and bloating, trying to deal with this because I don't want to stop taking it. Big problem is feeling like I have an earache all the time..	Been on Cymbalta for approx. 6 months. Really helpful with depression, but I have had the bloating etc that everyone talks about. Trying to deal with that. Weight gain, which I hate!! Has anyone had the feeling like you have an earache all the time?? This is driving me nuts.	F	61	6 months 30mg 1X D		6/25/2010
4	Anxiety, Depression	At first dry mouth, then weight gain. Some difficulty paying attention to things, but that might just be my personality.	I went on after suffering from severe panic attacks for 2 months. I took it for 18 months and had a huge reduction in the panic attacks. I'm about to work my way off of it, with the help of a doctor.	F	26	18 months 60 1X D		6/24/2010
1	Neck and Shoulder Pain/Depression	This is a comment for Dr. Abby @ http://www.justanswer.com/questions/2f5t9-can-cymbalta-cause-increased-ast-and-alt-i-have-been-on-60-mg. Your not a very good Dr. The effect of all medicines that are to be taken for a lengthy period should measured. I didn't have elevated liver enzymes until I took Cymbalta and my liver enzymes sky rocketed and then I had a world record tieing gallstone. After stopping and having surgery my enzymes went back down. Started it again to see what would happen because I suspected my Dr. was as ignorant as your are. Guess what, the liver enzymes sky rocketed and I even ended up in the hospital with rapid heart rate, high blood pressure and chest pain. Anyways, you need to get a clue and stop working for Drug companies pushing drugs that cause health problems. Dr.'s like you should be sued. You are negligent. Next, you'll say that I shouldn't drink. Guess what ignorant Dr. I don't drink. Cymbalta sucks and so do you as a Dr. In addition, bad Dr.'s like t		M	33	1 years 60 1X D		6/24/2010 Email History
2	chronic depression	insomnia, severe headache, hyperactivity	Noticed a change after first dose. Increased energy and motivation. Decrease in anxiety and obsessive worrying. Great in this respect, exactly what I was looking for. However, insomnia was a huge problem. Slept about two or three hours a night at most. Became extremely physically tired, but could not fall asleep. Severe headache that would not go away with over the counter meds. If not for the insomnia and headache, I feel Cymbalta would have been very beneficial to me. Very disappointing. I was directed by my doctor to stop taking it, and was prescribed something else. The headache and insomnia stopped within a day or so after I stopped taking it. I did not have any problems with withdrawal, probably due to immediately starting another med.	F	46	4 days 30 mg 1X D		6/22/2010 Email
3	Depression/Anxiety/Social Anxiety	At first, dizzy, nausia, night sweats,insomnia,creepy (for lack of a better term) feeling, decreased sex drive. All but the night sweats, insomnia and decreased sex drive went away pretty early on, within the first month. The side effects of skipped doses are aweful. Feels like pins and needles in my feet and dizzy even when missing only one dose.	I take 60mg in the am, 30 mg in the pm. Have had a total lifestyle change since I first started taking it, divorced, kids away at college, better diet, regular exercise, but the depression and anxiety is back big time with a new symptom, freaky dreams, and cymbalta isn't helping anymore. I want to change meds but I am terrified of the effects of even cutting the dosage down. I don't want to increase it because I am almost at the max daily dose (120mg) as it is. I would have never started taking it if I had known of the lasting side effects and the effects of coming off it.	F	45	4 years 60/30 mg 2X D		6/20/2010 Email
1	Anxiety	Jittery--my hands are shaky. I feel like a zombie. Detached. Talk monotone. No expression-flat effect. No Anxiety but cannot feel anything. --Numb-- Sleeping alot-10 hours.	I am not going to take this anymore b/c I don't want to be a zombie and cannot be for job. I have moderate fluctuating anxiety. I think this is for more severe anxiety.	F	38	2 days 30 mg 1X D		6/20/2010
5	Chronic pain, anxiety	Night sweats, insomnia, constipation	After suffering from several herniated discs in my neck and spending over a year living on narcotic pain relievers, I began suffering from anxiety. My doc prescribed Cymbalta and told me it would also help with the chronic pain. At first the only side effect I had was the night sweats. I had surgery for the discs and wanted off the Cymbalta because I was no longer on the pain meds. My doctor advised against it but I weaned myself off anyway. Did not have any problems weaning myself off although I had run out at an earlier point and had a severe anxiety attack. I weaned myself off very slowly. Night sweats and insomnia disappeared but my neck pain returned within days. I had lost my insurance and could no longer affford the Cymbalta but I was able to get assistance through LilyCares and made the decision to go back on the Cymbalta for the pain. It is worth the side effects to me. I have found that taking fiber helps with the constipation although I take double the suggested dose. Have not found anything to help with the night sweats. I have tried several things to help with the insomnia but no luck so far. I am considering cutting my Cymbalta back to every other day to see how that works.	M	42	1.5 years 60mg 1X D		6/19/2010 Email
4	Depression	I was fine on Cymbalta and it worked for the depression but then recently after 4 years I discovered and my doctor agreed that it was producing severe constipation and then gastroinstestinal issues. When weaned off cymbalta to see if the side effects would stop and didnt these past two months I mentally crashed and so I am back on it but at the 30mg and I don't want to go higher this is a happy medium for me. Cymbalta is very expensive also and most insurances wont pay for it. I had to go thru LillyCares.com to get assistance to cover it. In addition to taking the Cymbalta again, I discovered and my doctor agrees with me taking 1 probiotic, 1 stool softner, 1 colon cleanse tablet, and digestive enzymes when eating per day immensely helps my digestive disorder and severe constipation I developed while being on Cymbalta. I don't know how long it would take for Cymbalta to leave my system after being on it so long but the digestive issues are a done deal now and since my wedding is 2 mont		F	44	4 years 60mg 1X D		6/17/2010 Email
5	Premature Ovarian Failure	None the first time around. 4 yrs later - and 7 hours ago. 1st dose at 30mg. Belching and a very gurggly stomach. A little sleepy, too.	5 years ago I began to rage. I was angry, agressive, ready for and looking for a fight. I oozed hate. Severe night sweats, severe daily hot flashes, crazy 2 week + migraines, drastic mood swings. If I wasn't pissed, I was crying. No in between. I was diagnoised with POF (early menopause). I was given 60mg of Cymbalta by my Nurse Prac. B/c she wanted me to start slow, I was advised to take one every OTHER day for two weeks then one a day. One every other worked so well, I was scared to mess with it. No night sweats, no hot flashes, no rage, no mood swings, no hate, just me, myself and I. It was THE MIRACLE PILL. I took it for a year, every other day with absolutely no side effects and then quit. Cold turkey without any withdrawl symptoms. So I'm kinda shocked to see how everyone here has had such a hard time getting off it. Now I'm on it for anxiety and depression. Today was my first 30mg dose in 4 yrs and Dr. wants me to take it every day. I have suffered from severe optical migraines since I was 10 years old. I'm pretty good at medicating before pain, but I'm a little hopeful here as I didn't know it was also a treatment for migraine suffers. Will keep you posted. (O:	F	41	12 months 30 mg 1X O		6/16/2010 Email
3	Neuropathy	Acute loss of interest in sex, inability to reach climax - no sensitivity, mild constipation, dry mouth, uncontrollable yawning	Seems to help some with neuropathy, although it doesn't completely ease the pain and burning sensation. The first time I tried it, I got very nauseated and stopped taking it, but decided months later to take it with food and didn't have that problem again. Will probably stop taking it and go back to neurontin because of sexual side effects.	M	65	3 weeks 30 mg 1X D		6/16/2010
3	Anxiety & Depression	Euphoria, decrease anxiety, stable & calm mood, increase in confidence, loss of short-term memory.	I would rank this higher, but it absolutely affected my memory & it is still not quite what it used to be. Also, when I was weaning off of it, it made me feel SO SICK and miserable. DON'T MISS A DOSE OR YOU WILL FEEL IT, and I was only on the minimum dosage! I must say, though, it did help me at a time when I really needed it! I'm not on anything now and I feel fine.	F	27	2 years 20 mg 1X D		6/13/2010
2	Dysthymia	This has been no cake walk. The side effects that this medication has should make the manufacturer (Lilly) blush with shame. Anyone prescribing it should be required to take it for a minimum of six months. Each capsule has many SIDE dishes that have meant, SLEEPINESS, LACKING MOTIVATION, INSOMNIA, VIVID DREAMS OF A GARISH NATURE, EXCESSIVE SWEATING, ANTISOCIAL TENDENCIES, IRRITABILITY, DRY MOUTH, MEDICINE BREATH, WEIGHT GAIN, SERIOUS MENTAL MISTAKES WHEN DRIVING, CONFUSION, and others that I don't remember at the moment.	With all of the nastiness that this horrible drug represents I have attempted to come off of it twice only to come back on to it because of brain popping severity that one could only connect to as being in HELL!!! This garbage should be administered with a RED FLAG. In order to fall asleep I require additional drugs including TRAZODONE and TEMAZAPAM to help enhance sleep. I am now HOOKED on TEMAZAPAM as I am on the Cymbalta. My next order of business is to once again come off Cymbalta and hopefully the Trazodone and Temazapam later on. I will pull the devil capsules apart and take some of the time release grains out. I will carefully log each week as I do this to mark my progress and side affects. I expect this will take many months. What a shame (or is a SHAM!). If I have any problems with this I will ask for a new Dr. since the one I have now does not care what he prescribes. I notice that most people who complain about this bastard drug do not comment on what they will then take once they get off of it. This is a good indication of how the side effects of this garbage tops everything else. This almost smacks of a class action lawsuit against Lilly for their poisoning us. I feel that strongly about this!	M	49	5 years 60 1X D		6/12/2010 Email
5	Diabetic Neuropathy Pain	No bad side effects at all!!	This drug has helped the pain, helped improve my mood, and also aids in helping me to sleep.	F	50	21 days 30mg 1X D		6/11/2010
3	anxiety/depression	anxiety, drowsiness, insomnia, chills, loss of appetite, sweating, cloudiness, memory loss	Over the last 6 months I've experienced the separation of my parents after 38 years, life-threatening surgery for my mother, first death of a family member and extreme job dissatisfaction. The collection of these events have made me pretty depressed and anxious. My relationship with my fiance has really taken a blow as a result of these occurences. I began seeing a therapist a couple months ago, but I wasn't feeling the effectiveness. I decided to reach out to my physician for information regarding medication treatment. He prescribed Cymbalta, which I've been on for the last 4 days. It's been pretty horrible, thus far. I've been anxious at times, paranoid, very drowsie, sleeping for no more than 3 hours per night, loss of appetite, sweating, very cloudy thinking, forgetfulness. I'm toughing it out for another couple days, in hopes that my symptoms improve. Wish me luck!	M	28	4 days 30 MG 1X D		6/11/2010
4	severe anxiety, mild depression	First few days had major insomnia, which continues, but not as severe, and I've always had sleep issues to begin with. A little nausea here and there, extreme loss of appetite.	I used to take Zoloft which emotionally worked great, but packed on 8lbs in just 3 months from it. After 1 month of taking Cymbalta 7 of the 8lbs are gone! I don't feel as "mellow" just yet as I did on the Zoloft, I still have major bouts of irritation and frustration, but it's slowly getting better. I plan to continue taking it, as I'm really happy with it so far.	F	32	4 weeks 60mg 1X D		6/10/2010
4	Depression (Dysthymia) , Anxiety	Decrease in libido (not totally gone), ejaculation takes longer, morning nausea/loss of appetite, constipation, more frequent urination, excessive yawning (first two weeks), penile discharge (first week), jittery/high energy (first week), weight loss.	-I also take 200 MG of Provigil twice a day for Narcolepsy. -For the first two weeks I took clonazepam for the anxiety until the Cymbalta kicked in. - So far it has worked great for me and the side effects have not become severe enough to cause an issue. I was somewhat hyper/ talkative the first week (a major shift from being extremely quiet, removed, and antisocial), but that was mostly with family members. If I eat much of anything in the morning while I still have the mild nausea I will get diarrhea, otherwise I have had some mild constipation but that usually only makes me take a little longer in the bathroom so I moved some books in there for reading (reading has always been difficult because of the lack of interest, and excessive daytime sleepiness that would cause me to fall asleep repeatedly and become disoriented). My general level of anxiety has dropped quite a bit. I still recognize some of the thoughts and feelings I had before, but they no longer keep me from being able to do things as simple as taking a walk and it is much easier to communicate. My motivation level has increased a large amount and allowed me to actually have interest in creating art (an interesting/nice feeling for someone who has gone to a Fine Arts college for the last 3 years) and in life in general. I have gained a good amount of energy throughout the day and am actually sleeping better (which is still "fragmented sleep"). - I'm going to keep watching things.	M	21	1 months 60 MG 1X D		6/10/2010 Email
3	Fibromyalgia	Weight gain, constipation, and EXCESSIVE SWEATING!! I am sweating 24/7 and I hate it!	It seems to help somewhat with the muscle pain from the fibromyalgia but I'm wondering if a lower dose would eliminate some of the sweating. I can't keep the temperature any lower than I alreaady do.	F	54	6 months 30 mg 3X D		6/10/2010 Email
1	depression/anxiety	achiness, tiredness, restlessness, blurry vision, tingling in arms, legs and hands, increased anxiety, high blood pressure, belching, heartburn, loss of appetite, strange taste in mouth, alternating hot and cold spells, headaches, loss of feeling during sex	I have only taken cymbalta twice and am going to stop now before my symptoms get worse. I feel a lot worse than I did before taking it. I constantly feel as if I am on the verge of a panic attack, I feel like sleeping all day, but have difficulty sleeping for more than 1 hour at a time even during the night. I have aches and pains as if I have the flu.	F	33	2 days 30 MG 1X D		6/9/2010
1	depression	Short-term it helped my depression (6 mos). Then the dose was increased to 60mg and I began to experience panic and anxiety attacks to a much bigger extent. Heart palps, blood pressure and respiratory rise, anger, irritablity, inability to reason or function normally. Had to resign my job because of side effects. Withdrawl symptoms were so bad. (Headaches, insomnia, dizziness, nausea, emotional, easily irritated). Began to decrease amount of Cymbalta slowly by taking capsules apart and removing 5-10 beads on a weekly basis. It is taking forever.	I do not recommend this drug for anyone.	F	21	2 years 30-60mg 1X D		6/8/2010 Email
4	Fibromyalgia	For the first week, i had some nausea, loss of appetite & extreme constipation. After the first week, all but the constipation went away; however, I found a cure for that!	Don't let the harsh comments on here scare you--just remember, everyone is different. I've only been on it 5 weeks & it has helped my fibro pain; hoping the longer I'm on it, the more it will help. I never thought I was officially "depressed" but the pain did get me down & made me think negative thoughts. Since I've been on the medication, my spirits seem to be uplifted & I'm just happier in general. The cure for the constipation? Mineral Oil. Get a bottle & take 2TBS @ bedtime like every other day. You will be amazed at the results!	F	41	5 weeks 30 mg 1X D		6/6/2010 Email
4	Anxiety / Depression	First 3 days - Shivers, spacey, bad breath, numbness, diarrhoea, nausea, excessive yawning, loss of appetite, tremor, frequently needing to urinate. After week & now - All above reduced. Loss of appetite and excessive yawning?, reduced libido.	Long term deterioration of Job opportunities and work challenges caused and increase in my anxiety/depression. 3 days on 30 MG and then onto 60MG. Most side effects disapeared after 3 days. Cymbalta has definitely removed the "lack of interest" or "negativity and anxiety that was building in me. I now have more motivation in going about my daily activities and feel "normal again". Although one annoying side effect has been the feeling of tired/excessive yawning. I wonder if its a common side effect of Anxiety drugs? Was on Effexor previously (5 years ago) and didn't notice the yawning side effect but it did cause high blood pressure problems and Weight gain. Therefore, I am happy with Cymbalta benefits and will continue to use it to bridge me through this phase and not intending to stay on it for too long.	F	33	1 months 60 MG 1X D		6/5/2010
4	Anxiety/Depression/Panic Attacks	Muscle Twitches/Spasms	I feel so much better now- I used to get anxiety/panic attacks anywhere from 5-10 times a week ever since before I was diagnosed at 11 years old. In my life I have had 2 suicide attempts (the last one was about 14 years ago). My anxiety manifests itself in fits of anger, tears or total introversion. It has also come through as mild OCD compulsions: locking my car 7 or 8 times, dusting Everything every single night for about 2 hours, folding and refolding clothes etc. Since I started taking it, within about 2 weeks I noticed a difference. When I explained to my husband after a month that I could not take it anymore because it was too expensive, he INSISTED that I stay on it. HE said that he and my boys noticed a dramatic difference and that they hoped it stayed that way. So- I am back on and I feel better than I have in many many year....	F	32	2 months 20 1X D		6/4/2010
5	nerve pain from ruptured disc -neck	none that were significant	i'd been on assorted pain meds for the nerve pain from a ruptured disc in my neck. the nerve pain made me feel jumpy and irritable and uncomfortable. after i started cymbalta, the pain stopped. i didn't realize how significant the improvement was until i didn't refill immediately after i'd been on it several months. it was amazing the difference. perhaps those with bad reactions start with too high dosage initially? i know 30 mg is low, but it made a huge difference to my life.	F	50	2 years 30 mg 1X D		6/3/2010
4	corneal neuralgia	constipation, dry mouth, dizziness, sweating, loss of sex drive and ability to have orgasm, inability to tolerate heat. First few weeks I had very bad nausea.	Several times in the past 5 years I have forgotten to take it before bed. The next day I start feeling "weird" in the AM. As the day progresses I develop severe anxiety, dizziness, instability. I usually figure out that I forgot it but it takes several hours to start feeling normal again. Sometimes I feel confused or that I'm not completely "here" but that may be due to other meds.	F	40	5 years 60 mg 1X D		6/3/2010
1	depression	diarrhea BIG time if I did not take w/big meal, slight nausea, extreme tiredness, dialated pupils, blurry vision	I did not like this medication, too many negative side effects and no positive, could not keep up w/ my 3 yr old, and worse didnt want to play w/her any more, just felt like a zombie w/ diarrhea, yuck!	F	30	2 weeks 60 MG 1X D		6/3/2010
4	Anxiety and depression	Nausea,dizzyness,weight gain, heart burn, loss of Sexual appetite.	Its been a great experience. Of course we all know what we were without meds and what we are now is such a difference. I do feel more normal on meds, not as paranoid and I dont get uptight with the kids anymore. Im way more chilled. But I have a shocking memory now, Im warm alot - eg I dont wear alot of clothes in winter, and every morning I am nauseas. I hate the fact that Im not interested in sex anymore as I have been sexually active my whole life. Mind you I was also self sabotaging too. I just linked my weight gain to meds, and I realised recently my anxiety prob caused me to be super skinny. Whilst I like my new round curves, its a bit startling after 35 years of being skinny. When I startedon Cymbalta, I got heart burn for 3-4 days, and then nothing up until a week ago and now severe heart burn. I have only run out twice and those days were a nightmare. Dizzyness, nausea and other symptoms others were talking about. So I might go back to my doctor and see if I can go down to 30mg and see if the sex drive pics up and the weight gain and heartburn slows down. But yes, as mentioned before - not the best drug to run out of! YIKES. I used to take cypramol, and when I ran out of that, I didnt notice any side effects like Cymbalta. But it wasnt as good.	F	40	356 days 60mg 1X D		6/2/2010 Email
4	Depression	Initially; Restless Legs, yawning, inability to concentrate; tired during day. All subsided after 2 weeks. Longterm; Decreased Libido, not entirely gone. Difficulty reaching orgasm. Hair loss! Getting worse as time wears on.	Incredible difference in my Depression and Anxiety levels. Able to function normally and partake in activities that would have caused tremendous anxiety for me. Depression has subsided but not totally gone. Definitely give this drug time to work. First few days were ROUGH. But the libido and hair loss i can't live with forever..	F	40	7 months 60MG 1X D		5/26/2010
4	Bi-Polar, Anxiety, Psychosis	Dry mouth, sleepiness (for the first few days), couldn't orgasm the first week	I still tend to get dry mouth from time to time but I can tolerate it. I'm not sure exactly what it does to me since I started Neurontin at the same time. It does help with my mood but not the anxiety.	F	24	6 months 60 2X D		5/26/2010 Email
2	Depression	Deep-end mania.	For the first 3 weeks, life was getting a lot easier and I started to hope that I was going to come out of that long tunnel of depression. But at about 4 weeks, I became fascinated with geology and I could not stop picking up rocks. My pockets were full of rocks everyday. I would take time off work to collect. It took me a full 12 weeks to fully realize how delusional I had become (as opposed to moderately depressed but not delusional, before taking Cymbalta.) Hm, what else, yes...I was also missing meetings! My career was at an all time low! I kept getting fired. (But I was happy, well sort of.) If you have the time and inclination to become an artist however, this may be the drug for you. It really works great on depression. I also got incredibly fascinated with digital photography. I was extremely prolific. I loved what my senses were bringing me. I've got kids though and if I kept taking Cymbalta, I'ld be living in my van by now and not paying child support.	M	47	3 months 100 MG 1X D		5/25/2010
1	Depression/Anxiety	So "high" I got on my own nerves. After 2 weeks the "high" wore off and I was left in worse shape emotionally than before I started Cymbalta. Completely ruined my sex life even after coming off the medication.	I have been off this medication for 6 months now and I still have absolutely no desire to have sex at all. If your doctor reccomends Cymbalta for treatment of any condition you should run away. Quickly if you can!!	M	32	6 weeks 30mg 1X D		5/25/2010 Email
4	Anxiety	First 2 weeks on 30mg(dizzy, loss of appetite, sleepiness, nausea) 2 weeks on 60mg(HR 120bpm, heart palps, increased pupil size, increased BP, sweating, increase breathing), 2 years later (no libido, constantly tired, no motivation)	This med really has helped with my anxiety. I started out on 30 for 2 weeks then upped to 60. Had the aforementioned side effects and was brought back to 30. I have taken this for 2 years and have had no problems with anxiety. Unfortunately if I miss a dose I have the "light switch" problem as others have mentioned. It really does feel like lights are going off in my head and I get a severe headache, nausea, dizziness, and sleeplessness. Also, my libido has decreased to ZERO and it's awful. At my age you would never think this should be a problem. I'm calling my Dr. today to find out what we can do about this.	F	25	2 years 30mg 1X D		5/24/2010
2	Depression after my husband died	Didn't seem to help my depression - although I was somewhat more organized and directed. Feeling very tired, which has continued through the months of taking Cymbalta. Think I'll discontinue, under my doctor's supervision. Good luck. Hope it works for you.		F	71	1X D		5/24/2010
4	Depression and anxiety	At first, very spacey, dizzy, jittery and tired - it was somewhat difficult to function at first, but now most side effects are gone except sexual side effects (there's some dulling, but my libido is not totally gone).	I was skeptical that it was doing anything at first, but after 10 - 14 days on the right dose, Cymbalta really helped with my depression and anxiety. I'm glad I hung in there; it's a life saver. I would give it a few weeks before giving up.	F	42	30 days 60 1X D		5/22/2010
1	Depression and anxiety	Dizziness and vision problems - trouble focusing eyes, seeing tracers, strange pupils; one bigger than the other at times. Fatigue. Loss of appetite. Trouble concentrating. Jumpy.	The side effects are pretty bad. Especially the vision issues. The side effects are causing more anxiety, when I'm taking the drug to reduce it. Now I'm just constantly worrying about how I feel and if it's doing damage. I'm not able or motivated to do anything, since all I can think about is how messed up I feel and how hard it is to focus on anything and the strain of seeing straight is a constant distraction. I feel worse than I did before going on the drug.	F	34	4 days 60 mg 1X D		5/22/2010
3	Anxiety and depresseion	Dry mouth	Helped with depression but not with anxiety. I take clonozapam 2x day to help with anxiety & panic. Get panic attacks when going out of the house sometimes and migraines when under stress.	F	68	8 months 120mg/day 1X D		5/21/2010
4	Depression, Bipolar	I took Cymbalta for several years with few side effects. Unfortunately, I had to go off of it for 7 months due to a lack of insurance. I just started taking it again and the usual side effects are waning, with the exception of a horrible headache that won't seem to subside. I wake up with it in the morning and if I miss a dose of advil/motrin it comes right back during the day. Is this common?		F	38	2 weeks 60mg 1X D		5/19/2010 Email
4	Fibromyalgia/myofascial pain: back	Chills, very dry mouth, anorgasmia (inhibited orgasm). Fatigue that wore off after one week.	Only drug (tried 6-8 prescription meds) that has controlled upper back pain rt. myofascial pain (muscles). Has reduced my pain meds from 8-12 + 1-2 narcotics a day to just the Cymbalta and 1-2 OTC meds. Hoping side effects decrease with extended use.	F	52	3 weeks 60 mg 1X D		5/19/2010
4	Depression & Anxiety	Dizziness, inability to have eyes focus properly, headache. I only experienced these when quitting Cymbalta. If you are having any of this problems described above have your doctor increase or decrease in smaller increments. DO NOT EVER QUIT TAKING COLD TURKEY! Regardless of your reasons, you need to speak with your doctor about "weening" your system off of Cymbalta, as with all SSRIs.	I love it. I took Zoloft on and off for 12 years, and found I have fewer negative reactions to Cymbalta. I do not have climax or intimacey difficulties now.	F	29	2.5 years 90 1X D		5/19/2010
3	FM/CFD/fibromyositis/dystonia	hallucinations, loss of appetite, night sweats, night terrors, horrible after taste, etc... Eventually subsided. (Thank God!)	Doctors haven't really figured out what type of pain disorder I have. However, Cymbalta has been helpful. At first, it was a NIGHTMARE! Getting used to it was difficult. I stopped taking this medicine 4 times, when my doctor told me I had to take for at least three months in order to effectively rule it out as ineffective. Took it for a while, and it proved to be helpful. Last time I visited Johns Hopkins, the dr. decided to increase from 60 mg to 120. Now that I'm used it, the side effects have subsided.	M	30	1.5 years 60 mg 2X D		5/19/2010 Email
1	nerve pain	This is my second day i am using the CYMBALTA. My doctor didn't say about Nausea.So i was thinking i had bad food that why i am getting Nausea.Today i have read all the side effects. i am getting most of those(Nausea,Drowsiness,Vomiting, Yawning).	I hate CYMBALTA.	M	30	1 days 60 1X D		5/18/2010
1	anxiety	Chills, Extreme cold, loss of appetite, nausea, fatigue, drowsiness, dizziness, emotional numbness, racing heart, heart palpitations, panic attacks, vomiting, tight chest, difficulty breathing	My doctor put me on cymbalta for general anxiety while moving/changing jobs. She had given me the 50mg samples but on day 2, I had to call the doctors office. The first day I was extremely cold (I was freezing while wearing a sweatshirt on a 85 degree day), felt sick to my stomach, and couldn't eat anything. All I could do was sleep and shiver. The second day I was still cold, couldn't eat, but the nausea turned into vomiting. What really sacred me was that my heart started racing & fluttering. This sparked a panic attack & something that felt like an asthma attack. I'd started Cymbalta at 7am Monday morning and by 3pm Tuesday I was on the phone with the doctor who lowered my dose to the smallest possible. Then I took a 10mg pill and STILL had chills, loss of appetite, extreme drowsiness, and a racing heart. Overall, Cymbalta gave me way more to worry about than it ever helped.	F	24	3 days 10mg 1X D		5/18/2010
3	fibromyalgia/chronic pain	severe fatigue and lack of ambition	I switched from Zoloft to Cymbalta because the Zoloft didn't seem to be working anymore. Also Cymbalta has been aproved for fibromyalgia. I also have a pain pump dripping in my spinal fluid (fentanyl).I have experience severe fatigue and lack of ambition. I sleep constantly and don't want to do anything. I am going to stick with it because my doctor says I need to give it a good try. Maybe I need to switch from taking it in the am to pm. I would love to hear from someone who had a lot of symptoms that went away and is happy with the drug. Also, I have found a solution to constipation. Citricel an orange juice daily. You have to take it daily and sometime more, but it works for me.	F	61	10 days 60mg 1X D		5/15/2010 Email
3	Depression	As I posted before, when I first began taking it, i loved it. It immediately helped (I even began keeping a journal of my experience with it), and after reading some of the posts here, I attributed that to a placebo effect. It even helped me sleep better and I actually enjoyed the vivid dreams. In any case, after about a week and a half, I didn't feel all that great anymore. Still okay, but not great. Weird, because this is about the time when these types of pills are supposed to START to work. Anyway, it is the only pill of this type that I have stuck with, because I actually felt better with it (at first). By the time I visited my doc on the 7th of this month, I just felt 'eeeengh' (oh, and I had gained weight). He has now placed me on 60mg, and when I asked him for something for weight loss, said that these pills actually help lose weight. So, I have been on 60MG for almost a week, and feel just okay - nothing like when I first started taking it. Will stick with it a wh	Will continue to give it a chance.	F	32	6 weeks 60MG 1X D		5/15/2010 Email History
4	depression anxiety	side effects were a little tough at first but i was told you have to stick through it to see if it works. it takes weeks to get full benefits .	i am now able to function day to day. still dont feel good all the time but it put a big dent in my problems IF YOU RATE THIS DRUG WITHOUT GIVING IT THE PROPER TIME TO WORK THEN YOU DID LISTEN TO YOUR DOCTER IF YOUR NOT WILLING TO COMMIT TO THE WEEKS IT TAKES DONT WASTE YOUR TIME AND DONT POST HERE THAT YOU TRIED IT FOR 3 DAYS AND IT DIDNT WORK!!!! i do understand that these drugs do effect people differently and have considered this before my statement here. thanks...paul	M	46	6 months 60mg 1X D		5/12/2010 Email
2	depression and fibromyalgia	sleepiness, constipation, lack of appetite, weight loss, insomnia	I have found in begining this drug seemed fantastic and even lost a little weight; but then with doctor forgetting to renew my prescriptons, the nightmares started. In just the past year and a half, t times I have been forced to cut back to point of not having any medications for a month or two and then to go back on' it has been a nightmare, got to point of losing weight, not being able to eat, insomina, worsened depression, panic attacks and agoraphobia just to name a few. even though they eventually got my medicatons on track and take them like I am suppose to they no longer work for me; and terrified in going off them as symptoms were terrible; both physical and mental effects to where spent most of my days under covers in bed, and struggle to even go out when I need to, etc. If I had known all the side effects in taking and then being forced to go off, I would have never started this medication. If you have a choice, I would suggest that you not start unless you plan on taking it forever and your doctor will make sure you have it to continue to take.	F	62	4 years 30 3X D		5/12/2010 Email
1	Fibromyalgia	anxiousness, very "high" feeling, could not concentrate, weight loss, no appetite, extreme sweating all day and night, runny nose, could not focus, come vision problems,	The only good thing I experienced was weight loss. Taking this medication was like taking a street drug. Very Very bad medicine for me. It might work wonders for depression for some people.	M	40	40 days 30mg 1X D		5/12/2010
1	herniated discs- nerve pain	POISON!!!!! Sick from day one, stopped a wk ago and still sick! a wk later!!!nausea, runs, flu like, sea sick feelings, dizzy, no appetite. This drug ruined my birthday, mothers' day as I've been home bound for over a wk now. I'll take my chronic pain anyday over this drug! no more meds for me! stopped my one a day hydrocodone now too! I've never believed in meds and deal pretty well with 5 herniations and fusions w/o meds, meds don't cure, they are just a "band aide" - no more of their "trials" on me! if one gets this sick in only 3 days, what is this drug doing long term to our brain?????	Poison- nausea, runs, headache, dizzy, no appetite, horrid withdrawals!!!!	F	54	3 days 30 mg 1X D		5/9/2010
5	CFS/FM	Excessive drowsiness the first 10 days. Spent most of that time sleeping. No drowsiness now. Dry mouth, slight dizziness on occasion.	This medication has been a Godsend. I was diagnosed with CFS in 1995 which has morphed to FM. CFS/FM robbed me of life. I was always hesitant to commit to anything, not knowing how I was going to feel or how the activity would affect me. Though the FM pain was gone, the first 10 days on this medication was rough. I was so incredibly drowsy, sleeping most of that time. The day I had planned to call the doc to tell him I couldn't handle the trade off, I felt a little bit better so I held off on making the call. I am so glad I did. Within a few days I had my life back. I've pushed this drug to the limit by spending the last two weeks in the yard doing much neglected landscaping (moving rock & dirt, planting plants, etc.) without the typical crash and burn affects. Normally an hour or two of this type of activity would wipe me out for 2-3 days. The AZ heat normally wipes me out as well. I have also noticed that my joints don't pop like rice krispies anymore and my mood is much improved. I never realized just how much my mood was affected by my pain. I'm smiling, joking, loving and laughing again. My family and I are amazed at my energy level now. I understand this medication is not for everyone. In fact many of the comments here almost discouraged me from continuing it, after researching the drowsiness I was experiencing at that time. I'm so glad I didn't stop due to others experience. I'm living again. I'm gonna make up for some lost time now.	F	44	1 months 60 1X D		5/8/2010 Email
3	Nerve pain	Excessive yawning w/weird after affect where my ears are plugged for several minutes. VERY sleepy & have no energy. Getting up & moving in the morning is difficult. I shut my door at work & take several naps each day.	Dr. originally started me on 30mg. Pain in foot lessened a bit, but not much. 2 weeks later he upped me to 60mg. Pain has significantly reduced but this is when the sleepiness & lack of energy kicked in. I thought maybe it was because I was taking it so late at night (10 - 11pm) & then having to get up at 6am, so last night I took it at 8:30pm & feel much better than previously. I've only taken one short nap at work so far today & my yawns have been normal. Must admit most of the negative comments on here have scared me. I'm blessed that my Dr. did warn me about stopping cold turkey & to let him know if I want to stop & he'll wean me off. He also told me the co-pay for Cymbalta is expensive. So far he has just given me samples (he gave me a 'script yesterday). We'll see how it goes.	F	39	1 months 60mg 1X D		5/5/2010

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Average rating for drug: 2.9. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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