ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  to stop smoking HIVES!!!!!, crazy dreams, constipation, insomnia, serious indigestion and a feeling of not being able to swallow, vertigo do not take this drug...go cold turkey! after 3 weeks i broke out in hives..it started with itching on the palms of my hands and on the bottoms of my feet, now i am trying benadryl just to calm the hives so i can go back to work F 39 3 weeks
1/13/2005
 1  quit smoking Took Zyban in 2007 and it did wonders! This time around things are NOT going so well. I am completely paranoid (I think someone is trying to break into my home, watch me in the shower) I have a massive short fuse temper and I’m depressed. I did some research this evening and have noticed that most people who are using this for the second time have issues. I’m going off this right away I can’t live like this, I have never been like this. Do not take it!!!! My husband took it for 7 days and felt like self harming himself, this stuff is BAD NEWS!!!! F 28 3 weeks
1 pill 1X day
1/28/2012
Email
 1  to stop smoking paranoid aggressive anxious lack of sleep weird thoughts of harming others This drug nearly cost me my relationship, its totally not safe, the side effect i feel if I have continued would have proberbly ended up with myself being locked up for hurting someone, seriously not good, I have never been an aggressive person and normally see the best in people, but this drug is terrible, M 43 3 weeks
150 mg 2X day
1/5/2012
 1  Quit smoking Ringing in the ears (Tinnitus). An extremely stiff neck (needed a massage to release tension). My face felt like it was sun burnt and skin peeled off. Hives on my neck and shoulders. De-personolised feeling....agitated, very depressed. Aching feet. Insomnia, nightmares...the list goes on!! On the positive side I think that taking the Zyban suppresed my cravings for a ciggie, and I felt ok for about the first 3 or 4 days, then I stepped up the dose to 2 x 150mg per day after a week, this is when the side effects really kicked in. I thought maybe it was just me reacting to this drug, but obviously not!! I stopped taking the Zyban after 3 weeks, as I felt so bad....this should be a happy time having kicked a 40 year habit, but I felt worse than before I quit. The good news is I have been ciggie free for a month now, and slowly feeling better in myself. I read on the net that it takes a week or more for the drug to clear itself from the body once stopped. I would be reluctant to recommend taking Zyban. M 55 3 weeks
150mg 2X day
7/28/2011
Email
 1  Smoking Cessation Difficulty breathing, kept trying to take a deep breath but was unable to. Tightness in the chest, Constipation, Vivid dreams, Insomnia, gas, indigestion. This is my third time on Zyban. It works to give up smoking, but I really can't cope with the side effects. Rather go cold turkey. Slight 'fits' and heart palputations. I do not recommend Zyban. M 3 weeks
4/6/2006
 1  Anxiety My doctor put me onto Zyban as the escitalopram that I had been of for 6 years seemed to be not working. I was gaining weight and struggling to lose it. I started zyban 3 weeks ago. I stopped my escitalopram tapering it off in 4 days and adding zyban in once a day at first then two a day. The first week I noticed I wasn't as hungry and had Wicked dry mouth..so i was drinking lots of water..doesnt sound so bad does it. By the second week..i started having panic attacks..started to lose my personality..and became depressed. I lost 7 kgs in 3 weeks The third week..this past week...has quite literally been a nightmare. I had derealisation..feeling like you are in a world that isn't real...and it was scary. I couldn't sleep..when I did I had vivid dreams. I went to my dr 5 times in the 3 weeks and she was adamant this drug was the right one for me..i just had to ride the side effects out. The day after a drs visit I called the ambulance. I felt like i was going to pass out..probably from lack of food.. or pure fear. I went to the dr again the next day (yep should probably have a mug with my name on it by now) and she said to keep taking lorazepam to squash the side effects and assured me again..this too shall pass. That night ( last night) I hit rock bottom. I felt like i was a burden to my family. I would never hurt myself im too scared of dying..but i just felt like a massive burden and a complete mess. I emailed the drs and told them to ring me immediately in the morning. F 29 3 weeks
300mg 2X day
8/5/2020
Email
 5  to stop smoking i had a few side effects but not any major problems. Headache, insomnia and dizziness when i stood up. I was also a bit angry but that was probably nicotene withdrawl. The first three days on zyban were the worst. The first two days i felt really pissed off and bitchy and then the third day i felt really high and then the rest of the time i was on it, i felt normal. Wasnt tripping out or anything. It made me feel like i wanted something but i didnt know what it was. I think it was my body wanting the nicotene but my mind was like no i dont feel like that. Sounds weird but it worked! I really think it depends on the person with all these side effects. You just don't know until you try. Would you rather the chance of some side effects or die of cancer? I have quit now, and i used to smoke a pack a day and I thought nothing would help me stop. F 22 2 weeks
1/19/2006
 5  quit smoking feeling like im drunk all the time! loads of energy that drives my husband mad! i cant sit still, but the werse side effect of all is not getting a wink of sleep at all for the past 4 days ive been up all night whatching tv cos there nothing i can do... i feel charged buzzing round the house even after not sleeping its as if ive been on (drugs) this is my second week and im on the 2 pills a day and i have to say they are working a treat i dont have any desire to look at or smoke a ciggie im feeling better in the way im breathing, my skin looks great, i dont stink and the best thing of all my kids give me a propper kiss goodnight now (im no longer getting just the cheak) F 23 2 weeks
3/21/2007
 5  Stop Smoking minor joint pain, waking up every 2 hours, vivid dreams. I have taken anti-depressants for 4 years- celexa, effexor, paxil. I do not recomment this for depression. Paxil worked great for me for depression. Zyban has greatly reduced urge to smoke, but has had no anti-depressant effects. If anything, Zyban has made me feel more depressed and anxious. HOwever, I am keeping in mind it's only a matter of time. i do not have to take this forever, and the side effects outway the toxicity of smoking. F 25 2 weeks
11/18/2006
 5  Depression lost 5 pounds so far. Not interested in food or wine (unusual for me LOL) day 4 a little light headed - felt high. Kinda nice. Not sleepy all the time like I was on citopam. Lots of energy. Feel Happy. I have tried Prozax, zoloft, effexor, celexa, couldn't stand the side effects. Zyban is a different animal...really working for me...AND I've lost a little weight! a nice bonus to having life and personality back. Works for me. F 49 2 weeks
150 mg 2X day
8/17/2012
 5  to stop smoking Most annoying side effect is my mouth feels constantly strange. This happened 24 hours after taking dug, on day 12 now have bowel problems, stomach upset, anxiety, muscle soreness nothing Major but I dont plan to be on this drug any longer than I need to. This is a remarkable drug with exceptional power I feel uneasy about being involved with. I physically could not continue smoking up to my quit date I had to stop sooner and I didn't want to as I felt i would fail if I was stressed before my quit date. (You know when you normally cut down and are a basket case before you even give up)But I have stopped with next to no problems, It isn't easy but it isn't completely horrific like cold turkey. I know I have stopped smoking now forever and that has never been the case on other occasions when I have tried to quit. Not happy about the drug but the ends justify the means! F 30 2 weeks
3/6/2006
 5  stop smoking first few days dry mouth, couldn't sleep but I have a sleep disorder, anyway -- I didn't gain any weight, in fact I've been losing weight and right now I'm feeling positively anorexic, which is a little bit scarey NO sexual side-effects whatsoever. I honestly couldn't believe that it would work this well (combined with the patch). The first couple of days were hell but then I was almost euphoric. Extremely great mood but not so good now. Either way, the drug does what it's supposed to do F 44 2 weeks
2/12/2005
 5  Quit Smoking None. I was able to quit smoking within 10 days of taking the pill. Sometimes I have cravings but they are few and far between. Once when I thought that I wouldn't be able to get my prescription filled before work I freaked out and felt cravings coming on, don't know if it was just in my head. Works so far. Good luck! F 23 2 weeks
5/31/2005
 5  Quit Smoking Side effects are pretty bad. Really loud ringing in my ears and I'm totally confused and in a haize... what a nightmare before finals. I can say that I have completely quit smoking!! and sleeping (taking unisom for that.. left the smokes for a temporary pill popping habit.. but i'm in a pretty good mood, eh?) I can be around people who smoke and it doesn't bother me a bit. I won't be able to take this stuff the full 7 weeks like recommended because my head is really screwed up on it. Really bad!!! I feel weird to say the least... but I've tried to quit smoking 20-30 times in every other way possible and have been unable until now. For that, it's worth it all!! I need to make sure I never have to do this again!! F 29 2 weeks
12/11/2004
 5  To quit smoking Slight tiredness I have smoked for nearly 25 years now and zyban really helped me quit, very happy M 40 2 weeks
9/7/2007
Email
 4  stop smoking Have any other diabetics out there experienced this weird episode while having a hypo & taking zyban? My blood sugar was low & there was lots of noise and stress going on, when my thoughts literally siezed up,spiralling into chaos and i could not speak properly or ask for help. It was terrifying. I was fully aware that i had gone insane & could not think straight. It was so unbearable I wanted to be taken to hospital & be knocked out till it wore off. I was trying to ask for that but could only slurr "hospital"!!It lasted aprox. 20 mins. Ive had diabetes for 30 years & never "lost it" while having a hypo, Ive now had 2 of these episodes with low B S levels on the zyban. Have quit the fags though! YAY!!!! F 40 2 weeks
9/10/2007
 4  quit smoking Vivid, weird dreams, irritability and hostility/anger/agitation, sleep interruptions, strange thoughts, though not psychotic or destructive (disturbing because I can't control them), sadness (though this may be from missing cigarettes) This is my second time with Zyban (first time, 15 years ago). A 1.5-to-2-pack-a-day guy, I'm down to from 4 to 8 only at night. The pleasure receptors shut down, cigs taste weird, satisfaction and craving all but gone, yet I fear that I still won't totally stop while taking a very strong mind drug. I'll give it another week. Don't like the strange thoughts and the vivid dreams, although they have not been too unpleasant yet. M 54 2 weeks
3/6/2008
Email
 4  To quit smoking Insomnia, happyness i.e it's an anti-depressant M 33 2 weeks
1/18/2003
 4  Never touch a cigarette again! spaced out,hard to sleep,more energy than usual,mood swings ive been taking zyban for 2 wks, the leaflet said to quit after a week i smoked my lungs off in that 1st week i am now down to two smokes a day i used to smoke 1.5 packs a day im 21. I am confident i will break the habbit in days to come. M 21 2 weeks
2/26/2008
 4  smoking cesstation Mild headache just kicking in and some nausea. On day 13 I had blurred vision but it passed. Vivid dreams but sleep relatively OK. From day 3 was happy to throw away cigarettes after 27 years of smoking! Hoping side effects don't get worse but will tough it out for a couple more weeks because I desperately want to be and remain a non-smoker - a few weeks of side effects seem small price compared to side effects of smoking or the drama of going cold turkey. That said I have been fearful of developing the depression/spacey side effects and if I do I would stop immediately (rather die happy with lung cancer!) F 41 2 weeks
2X day
1/13/2011

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