LUPRON DEPOT-3 Reviews (LEUPROLIDE ACETATE)Average Rating: 2.6 (110 Ratings)Filter ResultsCompare LUPRON DEPOT-3 with similar:
Type: Rx Drug
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Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first). Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on LUPRON DEPOT-3: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT-3 | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | Endometriosis | Bleeding, temperature changes | I have had only great results from the 3 month Lupron shot I received. I did get a lengthy 2 week period of bleeding, and then the extra pain about 3 weeks after the shot was administered, but since then feel better than ever. My mood has actually improved. I used to be hot all the time, and now am more on the cold side and feel regulated. I am taking add-back therapy so that may be a helper. I am due for my second 3 monh shot at the end of the month, and am hoping that the results stay the same! | F | 3 | 1X day | 3/10/2011 | 4 | Catamenial Endometriosis - Pneumo | F | 37 | 1X M | 3/4/2014 Patient History | 3 | fibroids/endo | I took the first Lupron shot 11/06.When the first shot was given I felt a sense of calmness during the fist month. Afterwards I experienced endless cramping,skin crawls on forehead and face,headaches,mood-swings,loss of sex drive.Just before the second shot I was told that the fibroids had gotten smaller. They were 3 cen. and had shrunken to about 1 cen. After the second shot (2/07) I experienced the same calmness after the shot.Afterwards periods of mild depression,I gained 15 pounds , vaginitis from extremely dry vagina,I'm totally exhaulsted on a daily basis,now I'm starting to experience pain in my knees.I would not recommend this treatment for anyone for any reason. Although the fibroids are shrinking, the the side-effects are unhealthy. | F | 40 | | 5/4/2007 | 1 | PROSTATE CANCER | In 2007 I had a radical prostatectomy. In 2009 my PSA went up. Dr recommended Lupron depot. Did not inform me of possible side effects. Now I have no muscle strength, very poor endurance, hot flashes, very poor sleep, memory loss, very poor concentration, irritability, bouts of extreme depression, vision changes, and PAIN in legs. | When I went back to Dr he said my PSA was lower and would not need another injection. Stated I would never take another injection. This medicine has destroyed my life. I have been a paraplegic for 23 years. My life has gone from being independent to depending on others. I cannot make transfer into my car so now will have to buy van with lift. The pain in my legs seems to be bone pain mainly is in my left femur which has had no feeling for 20+ years. Due to the muscle weakness I have fallen and fractured two bones in calf. Dislocated a finger and suffered a torn rotator cuff and head trauma. THIS MEDICINE SHOULD NEVER BE GIVEN TO A PARAPLEGIC WITHOUT AN EXPLANATION OF POSSIBLE SIDE EFFECTS! I was given the shot Sept 1, 2009 and went to my 40th class reunion on Nov 21, 2009 and barely remember any of it. | M | 59 | 1 times ? 1X O | 7/16/2010 | 1 | Endometriosis | Hot flashes and night sweats so bad, I showered 3 + times per day. Terrible Mood swings, horrible agitation, anxiety, crying spells, nightmares, insomnia. so busy dealing with the misery of the side effects, I have no clue if he helped | F | 44 | 1 times | 9/12/2015 | 5 | Endometriosis and ovarian cysts | After I was diagnosed with level 4 endometriosis, my pain was so bad I could barley get out of bed most days I would just lay there and cry from the pain, I had a laparoscopy to remove lesions, I was told it would help me be pain free for years, 8 weeks after my first surgery my pain was back and worse then ever, my doctor recommended hysterectomy and an oophorectomy (since I already had children and was unable to have anymore anyway) I was pain free for awhile after my surgery and when my pain came back I wasn't sure if I was imagining the pain or if I could still really have endometriosis... I had another surgery and still did that's when my doctor recommended me on this shot since it won't seem to go away. I was fairly skinny 105 lbs and in great shape, after I took this shot I started packing on the pounds, was extremely moody, I had terrible hot flashes, night sweats so bad I would have to shower in the middle of the night, and I was either starving or could go days without eating. When I started my second round of lupron after another surgery my symptoms were a 100 times worse I started getting really bad insomnia and nightmares I maybe slept between 1 & 3 hours a night. This is the last time I will take this shot I would rather live with the debilitating pain then have the side effects from this shot. | F | 22 | 9 times 3.75 mg | 8/11/2014 | 4 | endometriosis | constipation, 5 lb weight gain the 1st week which disappeared after the 2nd week. | I feel good on Lupron so far. I have more energy and no lasting side effects but I'm only on my 1st month. I was worried to go on it after hearing all the horror stories but also realize that many women only come on the site to vent. I wanted others to know that it can help some people feel better and is not only a nightmare drug. | F | 40 | 1 days 3.75 1X M | 2/15/2011 | 1 | Endometriosis | This injection I had as one single to help shrink my womb, to prepare myself for a full hysterectomy. Immediately the site of the injection rose into a large lump on my arm. Was told not worry about it. About 2 weeks later things started creeping on me. Weakness in legs, severe lumbar back pain, painful soles of the feet, fatigue. Five years on I've ended up in a wheelchair, pain and weakness and depression has destroyed my life. I worked as a care assistant for years. I miss my job and this has turned not just my life upside down, but my families also. Really think and get every last bit of information before having this injection. | F | 45 | 1 days 1 shot 1X day | 9/17/2020 | 4 | to shrink very large fibroid | I have experinced mood swings the first month and hot flashes and insomnia have been ongoing. | I have not had any awful side affects from this drug. reading comments from sites made me nervous to try it, but my doctor said this was the only way to shrink my very large fibroid (17cm) If I do not take this drug to shrink this I will probably lose my uterus and cervix because of where the fibroid is. I have been taking lupron for three months and the worst side effects have been hot flashes and insomnia. I did have terrible mood swings for the first month though. However I have not experienced awful things. I would love to have a child someday and am trusting this drug to shrink this based on my doctors recomendation that this is our only hope. | F | 35 | 3 days | 7/31/2007 | 4 | endo/pelvic congestion | weight gain, headaches, severe hot flashes, mood swings,scaterbrained.. hard to stay focused | Although the side effects are less than pleasant it really has done wonders for me, I HAVE NOT HAD ANY cramping,heavy bleeding or pain I was dealing with on a daily basis. I was in constant pain before my injection. I do HIGHLY RECOMMEND THIS SHOT. I do already have kids but I would like to have one more I am not sure if I can get pregnant after the shot? Anyone have kids after the shot with out invetro or fertility drugs? | F | 29 | 3 days | 1/28/2007 | 1 | Endometriosis | Pain, and crazy mood swings. | I had the 1 month injection given to me 2 days ago due to supposed endometriosis, aka pain that wad only getting worse, periods getting heavier and more painful, and experiencing painful intercourse for nearly a year. I just had my 2nd child 3 months ago, was on the pill, which only made my mood and periods worse. Finally an ob recommended I try this instead of "different positions and more lube and throw some Mrotin in the mix for the pain." first of all, due to a stomach condition I can't even take motrin and right now I am in so much pain, and I have been alternating between pure rage and complete hopelessness...not to mention yesterday I had the first migraine I've had in years, and fluid retention...and yet they won't do another surgery. I've already had one ovary removed due to a lot of good sized cysts, and have 2 beautiful children(and 2 miscarriages), and am so Done with dealing with this...I am feeling very lied to by the ob and would never wish this hell on anyone except maybe a serial killer or something. Please tell me it gets better or at least some advise on what to do... | F | 23 | 3 days 3.5 1X M | 8/24/2011 | 3 | Precocious Puberty-daughter | My daughter has been taking Lupron for about 6 months. She has always had weight issues because of the other medication that she is on for precocious puberty also. However in the last 6 months has gained 30 pounds. Has anyone else experienced severe weight gain? The medication has stopped her periods at age 9 and hopefully will be able to give her full adult height. | F | 36 | 6 days | 3/26/2007 | 1 | severe pelvic pain | i was given this injection 6 times. i would not reccomend this drug to anyone out there. At first when my obgyn gave me the injection i noticed hot flashes right away... my moods were so bad and my family was really fed up with my irribility, and constant rages. i felt like i had morning sickness all the time. my doctor told me that in time with this drug the side effects would go away. yeah right!!!!! my bones started to hurt after the 3rd injection..my doctor told me that this would go away too. well i have had my 6th injection last month and thank God i am done with this....my bones still ache so bad... i need painkillers, but since the injections my doctor does not believe me that i amin pain with this because he said this drug shrinks the uterus and my pain should be almost gone. thats a crock of crap. im miserable and wish i had some support.... | PLEASE RETHINK ABOUT THIS BEFORE TAKING THIS DRUG!!!!!!!!!1 | M | 33 | 6 days | 1/30/2007 | 1 | wife with endometriosis | hot flashes, constant bleeding, head aches, pain, mood swings, depression. | my wife has endometriosis. this was the second time she had this treatment. She got a new doctor, she gave her a 3 months dose, in one shot! She has been worst, and she is constantly bleeding off and on. Right now she is in the hospital because of the bleeding and the pain. This treatment should be your last option. | F | 37 | 7 days | 11/4/2008 | 1 | Endometrosis/pelvic pain | All the standard (hot flashed, decreased sex drive, mental, 30lb+ weight gain) but the joint pain was the worst. 6 months off the meds before I had a medically triggered period and the joint pain only got worse. 5 years of infertility treatments, I no longer have a period and they don't know why, but think this med played a role. A year after discontinuing I was diagnosed with Rheumatoid Arthritis and every dr. thinks this medication triggered this disease. My RA is VERY sensitive to changes in estrogen levels--there is a belief RA has an estrogen link as it is more common in women. I now have 2 other auto immune diseases and have seen more than 20 dr's over 6 years at Duke, UTSW, Baylor and Northwestern. They all agree that this med did something to my system. If you have any auto immune disease in your family, do not take it!!!!! | F | 28 | 9 days | 3/11/2008 | 3 | Large Fibroid 10.5cm,in uterus/cerv | Wake up with Headache, stiff back n ribs, flu like symptoms, feel extra tried, BUT NO mood swings or hot flushes yet. | Abdomen increased in size after 1 week and was very uncomfortable, peeing every hour. By week 2, some decrease in abdomen but bleeding around normal period time. Treatment is to shrink fibroid prior to surgery, currently abdominal hysterectomy booked for July, desperately want to avoid surgery or want option for sub total not total hysterectomy. Tried Marina for six months prior but fibroid continued to grow. Hope this works as out of options. | F | 50 | 14 days 11.25mg 1X O | 4/22/2013 | 1 | Large Fibroid, Non-Stop Bleeding | Completely lost sex drive, acne (never had it before), excessive tiredness | I am bleeding as much as ever and still experiencing severe clots. In addition to the severe anemia symptoms, I am now so tired most days I find it difficult to go about daily activities. I wish I had gone right for the hysterectomy and skipped this part of the treatment. | F | 36 | 30 days | 10/30/2006 | 4 | Endometriosis | fatigue, weight loss, unexplained crying spells, night sweats/chills | I have had two months of shots, the normal side effects, and it is well worth it. The pain from the endometriosis had taken over my life and I was hospitalized twice. I had constant pain. Please know this is a personal decision and can change your life for the better ! I also do add back therapy and would highly recommend it. | F | 42 | 60 days | 7/3/2009 | 1 | Endomitriosis andOvarian Cysts and | When I received the 1st shot my pelvic pain went away I had hot flashes but did not realize that I was having so mucm body pain by the end of the second shot I can barely move from the pain I lost 30 pounds feel like a truck ran over me and had to take so many meds for Insomnia depression anxiety voice change and joint muscleuar pain and a feeling of complete mood swings and missery. I feel apathy and can not concentrate also the shot gave me memmory loss. I will not get another injection ever in my life again. Sure it took the pelvic pain away but I am afraid that I will suffer for a long time from the body pain. | I will never take it again. The reason I took it is that the doctor needed to see how I would do with the shot to prove that I have endometriosis. She was afraid to operate on me because I was on pain killers from the cyst and fibroids. The doctors that I saw 5 in total all said that cysts do not cause pain the only doctor who said that that cysts cause pain was the Emergency room Doctor I had to go there several times and he said that many women have severe pain due to Cysts, that I know for sure. I have spoken to many women and they all said that they knew someone or they themselves had one and they had severe pain. Now what? I wonder if anyone knows when will my body stop hurting? I hope to spread awarenwss that ovarian cysts are very painfull and that you should have them removed because the shot is not worth it. This is the worst I have ever felt in my entire life. Does anyone know what I can do to get this out of my system? And how long will my body hurt? | F | 47 | 60 days | 5/2/2007 | 4 | Prostate Cancer | I have been on Lupron Depot 3 for 4 months, I had prostectomy July 2007, The only side effects I have had from Lupron are hot flashes and lower back ache. both of which are tollerable, | I was very wary at having Lupron injection , I read alot of the comments on this site plus many other sites, But I must admit I really have not had any major side effects from this drug, I feel it is everyones choice as to whether you have this drug injected, Everyone reacts differently to all chemicals , I feel the positives out weigh the negatives with this drug, I suggest people should use their own discretion in decisions, Not to just take what others have to say, We are all indaviduals and God gave us the ability to think for ourselves, Use that ability in every way possible to fight what ever cancer or disease you may have. I attend a support group each month, I have found it a great way to learn, It also allows you to be able to speak about your experiances regarding Lupron , Radiation ECT. I can only speak of my experiance with this drug, Maybe it works better for males than females, But I feel one never knows unless you try it, But please dont believe all the negatives you re | M | 59 | 120 days | 4/14/2008 |
LUPRON DEPOT-3 (LEUPROLIDE ACETATE): Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys). FDA Approval Date: 1997-03-07 (Sources: U.S. Centers for Medicare Services, FDA)