LUPRON DEPOT-3 Reviews (LEUPROLIDE ACETATE)Average Rating: 2.6 (110 Ratings)Filter ResultsCompare LUPRON DEPOT-3 with similar:
Type: Rx Drug
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Results are sorted by Date from oldest to newest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on LUPRON DEPOT-3: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT-3 | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | Premenopausal breast cancer | Weight gain, loss of energy, dyspareunia, depression. | I have taken this for estrogen sensitive breast cancer - to put me into a premature artifical menopause, so that I can take the anti-hormonal medications usually given to postmenopausal women. Lupron is called Prostap in the UK, and the 3-month injection has the same effects as the once-a-month injection, but (obviously) with only one injection every three months. Am now back on the once-a-month injections, this time with fulvestrant (faslodex) instead of arimidex, which stopped working. If the fulvestrant works, I might go back on the once-every-3-months injections. Otherwise, I shall go off both and have to undergo chemotherapy. Side effects include weight gain (including middle-age spread), tiredness, dry hair (?), vaginal atrophy (dyspareunia), etc. plus, not surprisingly, depression. | F | 49 | 6 months | 11/6/2005 | 1 | endometriosis | extreme weight gain 40 lbs., headaches, mood swings, hot flashes, loss of sex drive, memory loss, fatigue, insomnia, vaginal dryness, vision problems | I would not recommend that anyone take this medication. My endo was only a stage 2. I would much rather deal with the pain than all the side effects. I have now been off the shot for three years and am still experiencing these side effects. My weight gain is the worst part to me. It has led me to have decreased self-confidence. I did not really begin to realize the weight gain until it was too late. I feel this medicine was the worst thing that has ever happened to me. I feel that my doctor could have given me a better option since my case was not severe. | F | 21 | 6 months | 1/2/2006 | 4 | Endometriosis-stage 3 | weight gain 35 lbs., headaches, mood swings, hot flashes, loss of sex drive, memory loss, fatigue, insomnia, vaginal dryness, vision problems | Depot Lupron was my only option other than having a hysterectomy to relieve the Endo pain and to also preserve my uterus. I haven't had children due to the Endo and my doctor hoped that if the Endo could be eradicated from my system that maybe I would have a chance to concieve. My doctor also said that at 43 I was about 10 years away from going through Menopause and going through it 'naturally' is better on a body then forcing it to go through it because of a hysterectomy. So with my doctor's reccommendation I went with the Depot Lupron. I received four injections;Aug 2004, Nov 2004, Jan 2005 and Apr 2005. In Jan 2005 my doctor put me on Progestin to relieve the severity of the HOT flashes that I was getting every-hour-on-the-hour, 24 hours a day, with each episode lasting approximately 15". I was miserable and extremely tired from a lack of quality sleep. By Dec 2004 my weight had started increasing and after starting the Progestin my weight rapidily increased. By April 2005 I ha | F | 43 | 8 months | 7/25/2006 | 3 | fibroids | Night sweats, Hot flashes, Chills, Brain fog and memory issues, Weight gain (inability to feel full), Joint Stiffness in morning, Back pain, Fatigue, Vaginal odor (showers don't help), Loss of sex drive, Vaginal discharge | I'm trying to keep my uterous. Will have surgery of some sort in Dec. I can't tell if the fibroid is shrinking, but I feel even more bloated and have bladder problems due to the fibroid size. I am very distrubed by my weight gain and my insatiable appetite. I will eat a meal, and still feel ravenous right after I'm done. This is very upsetting. I may have to join weight watchers again just to limit the damage. | F | 30 | 3 months | 8/9/2006 | 3 | endo/Fibroids | I am 32 and had myomectomy in order to preserve my Uterus, and was diagnosed of Endo aswell, I am on lupron since april till october, I have gained 9LBS, with Hot flashes 25 Hrs, bad mood swings, and still the doctor doesnt know if its has been eradicated or not. I guess this is the only best option to ssave my uterus. | F | 32 | 6 months | 9/2/2006 | 3 | endo/Fibroids | Hot flashes, Weight Gain, Mood Swings, | I am 32 and had myomectomy in order to preserve my Uterus, and was diagnosed of Endo aswell, I am on lupron since april till october, I have gained 9LBS, with Hot flashes 24 hrs, bad mood swings, and still the doctor doesnt know if its has been eradicated or not. I guess this is the only best option to ssave my uterus. | F | 32 | 6 months | 9/2/2006 | 1 | Endo pain | Severe insomnia, severe weight gain, severe hot flashes, muscle tenderness, joint pain, memory loss, mood swings, depression. | I feel that taking Lupron was the worst mistake I ever made because of what it did to my body. Every body reacts differently to drugs but for me my body doesn't look or feel the same and No doctor can give me a reason why. I feel like there definatly needs to be more research and stats done on Lupron. The Script Assist people made me feel like I was crazy for blaming my weight gain and muscular pain on the Lupron. I am still trying to figure out what exactly changed in my body from this drug. In todays world you really need to be your on advocate because nobody else will! | F | 31 | 6 months | 9/10/2006 | 1 | Large Fibroid, Non-Stop Bleeding | Completely lost sex drive, acne (never had it before), excessive tiredness | I am bleeding as much as ever and still experiencing severe clots. In addition to the severe anemia symptoms, I am now so tired most days I find it difficult to go about daily activities. I wish I had gone right for the hysterectomy and skipped this part of the treatment. | F | 36 | 30 days | 10/30/2006 | 1 | Undiagnosed but possible Endo | After one week of my injection, my pelvic pain became more severe than it ever has been, and leg and joint pain worsened. Research I have done since allowing my doctor to give me this injection tells me I should have never allowed it and won't be getting another one. | I was given another prescription for Norethindrone which is designed to help with the menopausal side effects of the injection. Why this is helping to back of the pelvic pain, I have no idea. (neither does my doctor) I have tried backing off on the dose since but the pain seems to come right back so I am staying on my dose of 10mg a day. The leg pain seems to come and go but I have had a few bouts that are enough to make me cry, and can't seem to find a way to help that. I have been taking a pain medication every night before bed to try to help this, but it is not something I can take during the day if I go to work. I have appointments set up with two other doctors in the next few months to find some help with this. Research suggests that the best way to resolve endo is to have laproscopic surgery to exise it and that is what I will be asking about with these new doctors. Good luck and God Bless to all who have agreed to try Lupron! | F | 41 | 5 weeks | 11/23/2006 | 1 | endometriosis | After recieving the first injection on Oct 9 2006 I had severe headaches for the for two weeks directly after the shot. I continued to have them not as bad as severe but still bad enough. Currently, it is six weeks after my shot. I have the hot flashes and some night sweats, as I expected, but I DID NOT expect this horrific joint pain. It is almost indesricebable. I am suppose to take another shot on Dec 31st but you can forget that buddy! I also learned after the shot the this is irreversable! By the way THIS IS NOT A CURE!!!!! It is only to TEMPORARILY stop the syptoms! My doctor should have been more informative about the possible serious side effects!!!!! Now I have to SUFFER for two-three more months. PLEASE BE CAUTIONED before taking this medicine. I don't believe that people who have taken this drug are being honest if they say this drug did'nt effect them. (WHETHER we react differently or not)Pray for me if you believe in prayer!! (I do) | F | 35 | 7 weeks | 11/23/2006 | 4 | Endometriosis | Hot Flashes, joint pain,severe mood swings, blurry vision, breakthrough bleeding, some crampng with the breakthrough bleedng | I took this in 2004 for 6 months and soon after I got pregnant with my daughter. I'm taking it again cause we want to get pregnant again but this time the side effects are worse. I'm not sure I can take them till march 07. Its a hard drug to be on and you have to expect major side effects. | F | 25 | 3 months | 12/5/2006 | 1 | Edometrosis | Horrible leg pain, hot flashes, weight gain (47 lbs) | It has been 10 years; I am still suffering!!! It destroyed my health; my body!!! DONT DO LUPRON!!!!! | F | 33 | 6 months | 12/11/2006 | 1 | Endometriosis | Severe joint pain, hot flashes, insomnia, fatigue, low-grade fever, low sex drive, weight gain (from 112 to about 122), stabbing headaches, muscle weakness, vision changes. | I started the Lupron injections six months after a failed laparoscopy to remove my endometriosis. For the first two injections I had the typical side effects of hot flashes, insomnia, fatigue, low-grade fever, and low sex drive. My third and final injection caused horrible joint pain that migrated around all of my joints aside for my spine and took a full year to ultimately dissipate. While taking the drug, I also had intermediate stabbing headaches that would come on in the back of my head, throbbing deeply and painfully with my heartbeat for a few minutes before disappearing. I have not had a recurrence of those headaches or the above symptoms per se. However, three years later, I now suffer easy tendon injury and flareups of joint pain as well as having multiple abnormally low hormone levels. I did ultimately decide on having a second laparoscopy where it was discovered that the majority of my pelvic pain was from a large ovarian cyst as well as multiple adhesions from my first surg | F | 30 | 9 months | 12/30/2006 | 1 | Endometriosis | Severe joint pain, hot flashes, insomnia, fatigue, low-grade fever, low sex drive, weight gain (from 112 to about 122), stabbing headaches, muscle weakness, vision changes. | I started the Lupron injections six months after a failed laparoscopy to remove my endometriosis. Other than the more common side effects during the first two shots, the third and final injection caused horrible joint pain that migrated around all of my joints aside for my spine and took a full year to ultimately dissipate. While taking the drug, I also had stabbing headaches that would come on in the back of my head, throbbing deeply and painfully with my heartbeat for a few minutes before disappearing. My endometriosis pain did come back after the Lupron stopped working. Now, three years later, I suffer easy tendon injuries and flareups of joint pain as well as having multiple abnormally low hormone levels. A second laparoscopy discovered that the majority of my pelvic pain was from a large ovarian cyst as well as multiple pelvic organ adhesions from my first surgery, with only a small amount of endometriosis visible. In the end, Lupron didn't help me at all. I strongly suggest tryi | F | 30 | 9 months | 12/30/2006 | 4 | endo/pelvic congestion | weight gain, headaches, severe hot flashes, mood swings,scaterbrained.. hard to stay focused | Although the side effects are less than pleasant it really has done wonders for me, I HAVE NOT HAD ANY cramping,heavy bleeding or pain I was dealing with on a daily basis. I was in constant pain before my injection. I do HIGHLY RECOMMEND THIS SHOT. I do already have kids but I would like to have one more I am not sure if I can get pregnant after the shot? Anyone have kids after the shot with out invetro or fertility drugs? | F | 29 | 3 days | 1/28/2007 | 1 | severe pelvic pain | i was given this injection 6 times. i would not reccomend this drug to anyone out there. At first when my obgyn gave me the injection i noticed hot flashes right away... my moods were so bad and my family was really fed up with my irribility, and constant rages. i felt like i had morning sickness all the time. my doctor told me that in time with this drug the side effects would go away. yeah right!!!!! my bones started to hurt after the 3rd injection..my doctor told me that this would go away too. well i have had my 6th injection last month and thank God i am done with this....my bones still ache so bad... i need painkillers, but since the injections my doctor does not believe me that i amin pain with this because he said this drug shrinks the uterus and my pain should be almost gone. thats a crock of crap. im miserable and wish i had some support.... | PLEASE RETHINK ABOUT THIS BEFORE TAKING THIS DRUG!!!!!!!!!1 | M | 33 | 6 days | 1/30/2007 | 1 | severe pelvic pain | I was given this injection 6 times. i would not reccomend this drug to anyone out there. At first when my obgyn gave me the injection i noticed hot flashes right away... my moods were so bad and my family was really fed up with my irribility, and constant rages. i felt like i had morning sickness all the time. my doctor told me that in time with this drug the side effects would go away. yeah right!!!!! my bones started to hurt after the 3rd injection..my doctor told me that this would go away too. well i have had my 6th injection last month and thank God i am done with this....my bones still ache so bad... i need painkillers, but since the injections my doctor does not believe me that i amin pain with this because he said this drug shrinks the uterus and my pain should be almost gone. thats a crock of crap. im miserable and wish i had some support.... | PLEASE RETHINK ABOUT THIS BEFORE TAKING THIS DRUG!!!!!!!!!1 | M | 33 | 6 months | 1/30/2007 | 1 | endometriosis | hot flashes, significant mood swings, weight gain, skin crawl | I took one full 6 month cycle of Lupron Depot. A year later I began another cycle after my hysterectomy. I quit taking the shots after the 2nd month.. I will NEVER take this medication again. The side effects were too severe! My personality completely changed while taking this drug. My doctor wants me to take the drug again because I am still in so much pain. I told her that I would rather endure the pain twice a month than take the medication. That is how bad I think the side effects are. I would really consider the side effects before taking this medication. Also, if you choose to take the medication, ask for the one month shot so you can quit if it is too hard on you. | F | 38 | 1 years | 2/10/2007 | 3 | Precocious Puberty-daughter | My daughter has been taking Lupron for about 6 months. She has always had weight issues because of the other medication that she is on for precocious puberty also. However in the last 6 months has gained 30 pounds. Has anyone else experienced severe weight gain? The medication has stopped her periods at age 9 and hopefully will be able to give her full adult height. | F | 36 | 6 days | 3/26/2007 | 4 | ENDOMETRIOSIS | HOT FLASHES MINIMAL MEMORY LOSS UPON FIRST SHOT-SLEEPLESS NIGHTS BUT WENT AWAY | I STILL HAVE PAIN BUT NOTHING LIKE BEFORE I STARTED THE MEDICATION I HAVE COMPLETED MY SIX MONTHS WILLING TO TAKE SHOT AGAIN MY DEPENDENCE ON GOD (PRAYING) FOR SUPPORT HAS HELPED ME THROUGH THE MOOD SWINGS.I WAS AT A POINT WHERE I WANTED TO STOP TAKING THE SHOT BECAUSE OF THE TERRIBLE HOT FLASHES IN THE FIRST TWO MONTHS THAT EASED I THINK AFTER THE THIRD SHOT. I HAVE READ OTHER COMMENTS, IT APPEARS THAT NOT EVERYONE HAVE THE SAME EFFECTS NO TWO PEOPLE ARE EXACTLY THE SAME OR HAVE THE SAME CHEMISTRY. | F | 39 | 6 months | 4/9/2007 |
LUPRON DEPOT-3 (LEUPROLIDE ACETATE): Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys). FDA Approval Date: 1997-03-07 (Sources: U.S. Centers for Medicare Services, FDA)