EFFEXOR XR Reviews (VENLAFAXINE HYDROCHLORIDE)

Average Rating: 3.0 (2225 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

EFFEXOR XR  (VENLAFAXINE HYDROCHLORIDE):  Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 1997-10-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on EFFEXOR XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR EFFEXOR XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression/Mild Anxiety {35mg for the first 2 days} sleeplessness, jaw clenching, hyper activeness, restlessness and finally 3 days later a collapse! (faint). ------------------------------------------------- {10mg self-reduced dose for 2 months} often became easily muddled (dopey), an inability to keep to my diet hence slight weight gain, decreased apathy and reduced hesitation to act on my thoughts. Took half a 75mg pill for the first 2 days. It felt like i was on speed and then i suffered a collapse on the 3rd day. So Doc switched me to Celexa which i hated! Celexa felt like i was imploding and more depressed the longer i took it (for 2 and a half weeks). So i got an idea; to take Effexor again just in smaller doses, since it made me so energetic. Long story short, I've been reasonably happy with Effexor, my apathy reduced noticeably. The only down side is that i often would get muddled (like ask stupid questions and forget things easily). Doctor found out i was taking the Effexor outside of its capsule so told me to switch to a new brand, Pristiq, which he says is similar just in tablet form. F 29 2 months
about 10mg 1X day
5/19/2010
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 3  depression loss of appetite, occasional sleeplessness and nausea. I went through the worst HELL ever when I went 4 days w/o taking the medication because i was having a problem getting Rx refilled. The side effects were HORRIBLE: dizziness, extreme & endless nausea, headaches, major anxiety, uncontrollable crying episode...it was bad. When I finally got the Rx refilled, I felt like a druggie desperate for a quick fix--i NEEDED it just to take away the horrible side effects. I want to get off the medication because I don't feel like it's working anymore but my doctor says I'm at the highest dose possible for this drug so I should just stick with it. F 31 8 months
300 mg 1X day
5/21/2010
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 5  Anxiety Weight gain; especially belly fat. About 10 lbs over 1 year without changing my diet or exercise habits. I have been thin all my life - size 6. After reading other users internet blogs I realized that Effexor XR does cause weight gain in some persons. For anxiety it worked really well with no other side effects other than than the weight gain. F 40 1 years
37.5 1X day
6/7/2010
 4  depression and anxiety weight gain, some jitters, loss of libido If you are taking this drug and it works for you, stay on it. I weaned off of it and plunged into a horrible state the likes of which I had never experienced. The strange thing was, when I went back on it it did not work as well. I felt flat and couldn't laugh. Now I am trying Cymbalta, which I pray will work since this has been six months of Hell. F 44 2.5 years
150mg 1X day
6/11/2010
 3  Depresion & GAD more hyper /anxious -yet more energetic though..just tried cymbalta had alot of anxiety on that-now trying Effexor. Acne , hyper, insomnia, diarrhea , fogginess Anyone had any rash or increase acne? ???got this horrible ??acne rash behind my ear..looks like pimples but not? weird , got it after starting meds F 38 2 weeks
at 75 now 1X day
6/14/2010
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 5  Anxiety/Panic No side effects whatsoever I have been on Effexor XR twice before. Both times it significantly reduced my anxiety within a week. Going off Effexor wasn't that bad as long as you go off slowly. Recently I restarted taking Effexor XR due to a return of anxiety. It is working as it always has. Prior to restarting Effexor XR I tried both Lexapro and Zoloft. Both of those medications made me sick as a dog. I am so happy that I respond so well to Effexor XR. It makes me feel normal again. M 47 4 years
37.5 mg 2X day
6/19/2010
 3  depression/fibromyalgia Really helps with social anxiety and depression. Side effects are weight gain and horrible sweating. I really would not recommend starting though because when and if you want to go off of it, it is so awful to try...I felt suicidal, not typical at all for me...decided to stay on it to avoid withdrawal so PLEASE don't start. F 63 7 years
75 1X day
6/29/2010
 3  Depression/OCD Nausea, staring into space, delayed orgasm, increased anxiety at times Good for OCD and anxiety but really didn't help with depression so my pdoc switched me back to paxil with no taper. Even after taking for just 30 days the withdrawal was really significant. I felt like I was a having a really bad allergic reaction, but after resuming at 37.5 felt fine. M 38 30 days
75mg 1X day
7/2/2010
 1  Anxiety, depression Strange itchy rash on my skin-scared for life now.. swelling of legs and ankles, eventually entire body, bloating, constipation, loss of "caring".. no sex drive, insane sweating.. dizzyness, heart palpatations. These all occurred gradually as the dose was upp'd and when I complained to the dr's (three) they didnt know what to do and at first denied it was the effexor- eventually weaned me down- and all smptoms disappeared. Cost hundreds of dollars to find out this medicine was CRAP! F 36 1 years
150 MG 1X day
7/3/2010
 1  depression after missing 2 days of dosage (forgot to fill it): nausea, dizziness, MASSIVE headache, "brain surges", blurred vision, inability to concentrate. I went through this twice. The second time I began researching the drug online and seeing how so many others were having issues with it. I know you are suppose to come off the drug slowly, but by that time it was almost out of my system completely, so I just dealt with the side effects and felt completely different after a week. That week was hell, but to get off this drug was heaven. Don't take! Stick with the older drug combinations such as Wellbutrin & Zoloft. F 28 4 months
1X day
7/9/2010
 5  Depression For the first few months I had sexual side effects but they went away. Some weight gain The only drug that ever helped me. Others did not work or had bad effects. The "brain jitters" everyone talks about are very true when missing a dose. They are really no biggie, to me anyway. Over all my mood is good, I am much more productive generally. I tried the new generic version and it does not work the same. BEWARE. Even though it's cheaper, the wreth brand works different and much better. I am waiting to talk to my doctor as to why but this is in the literature. There is a difference in this generic. If you are starting out I would defently suggest the name brand to see if it helps. Once stable, then test out the generic for yourself. M 34 1 years
150 MG 1X day
7/11/2010
 1  Migraines Extremely tired...sleeping 15 hours a day sometimes. Migraines continued. Numb. I needed to get off this medication to do a sleep study. I got VERY ill. Within 2 days of going off 37.5 mg I was vomitting and had nausea. It has been 15 days and I still feel awful. Migraines, muscle aches, tired, gastrointeritis, bloated, dizzy, shocks, hard to concentrate, brain doesn't track, this has been a NIGHTMARE. My doctor did say that Paxil and Effexor do have many withdrawl effects...however, they should be gone by now and aren't. I do not want to start taking this drug again. This is scary..I am not able to work and get things done. F 49 7 years
300 1X day
7/16/2010
 5  for hot flashes! none I have only been on this for 2 wks but after one week my hot flashes stopped! This was wonderful since I just started having them 2 months ago and they were every 30 minutes! I feel happy and perfectly normal otherwise F 50 14 days
75 mg 1X day
7/23/2010
 4  Anxiety Side effects included increased sweating, permanently dilated pupils, nausea, teeth grinding/jaw clenching, increased heart rate (90 bpm) and increased blood pressure. The nausea and sweating subsided after the first month. Despite the side effects this drug really did help me to gain some balance in my life, I am now tapering off slowly with no real withdrawal syptoms. My main reason for coming off is that the drug tended to dull all of my emotions and I kind of want to feel things fully again. F 25 1 years
75mg 1X day
7/27/2010
 2  Depression Have just been switched to generic after taking brand name for 5 years, and have been very ill - feels like withdrawal, which is nightmarish. Generic has a problem - don't know if it doesn't release right, or what (since Effexor XR is extended release) - it has made me very ill - anyone else with this problem, please let your doctor and pharamacist know - please get the word out that there is a problem with this generic! F 40 5 years
75mg 1X day
7/30/2010
 2   shaking, withdrawal symptoms I have used brand named for many years. If I missed a dose in the early morning, withdrawal effects would not show up until late afternoon. With generic, withdrawal effects will show up by 10:30 in the morning. M 43 7 years
1X day
8/1/2010
 2  Anxiety/Depression There are no side effects from taking it -- but HORRENDOUS side effects from discontinuation. I've been trying to discontinue (slowly, by lowering dosage) for about 7 months now. The withdrawal is ridiculous. If I could go back and time and never take it I would in a heartbeat. M 25 7 years
150 1X day
8/10/2010
 5  depression F 59
300 mg 1X day
8/12/2010
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Patient History
 1  anxiety As far as I am concerned, this drug is poison. It made me nauseous, dry mouth with horrible taste (I even scheduled an additional teeth cleaning with my dentist.) When I tried to discontinue it, the nausea got worse. I also talked to a nurse at my doctor's office who said that she had a terrible time come off of it and had bad headaches too. I realize that this medication may work for some people. However, I don't EVER want to even look at the name of this again. It did me no good (how can you get less stressed if you walk around feeling sick to your stomach constantly?) I will NEVER go on this med or anything like it again. F 60 2 months
37.5 - 75 1X day
8/14/2010
 5  depression/PTSD frequent urination, weight loss, loss of appetite I have no desire to eat a large amount of food, which isn't a bad thing. It took about a week for me to feel a difference. I feel like myself again. I was really moody all the time before taking this drug. My depression went away almost completely. I no longer get really angry and it seems like I have a longer "fuse". My husband even noticed that I seemed more happy and complained less. This drug is wonderful. I take the generic version, however the doctor said that may be why I get pains in my stomach, so I am switching to the name brand in two weeks. F 30 3 weeks
75 MG 1X day
8/17/2010

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