There are 304 ratings for the drug: MIRAPEX in the Askapatient database.

Key to ratings for mirapex: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken		Date Added
				F  M
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2	RLS	At first, I had no side effects. Until reading this forum, I thought I was coming down with Parkinson's because I have a chronic shake! I don't drink or smoke and eat well, healthy life style. Now I shake, I have chronic headaches, very vivid and wierd dreams, disoriented, heavy night sweats and a vague feeling of being disassociated. I've gained weight and it only helps my RLS a little. I think I'll go off of it and just exercise my RLS away, gotta be better than walking around like a shakey old lady.	I usually only take 1/2 of .25 mgs, still have many side effects. Tired of the shaking and headaches.	F	52	6 months		2/3/2010 Email
5	Sleep Behavior Disorder	Possible weight gain.....I take a lot of other meds also:-(	Has really helped, along with klonipin, to keep me from acting out my dreams. Consequently I now get a good nights sleep.	F	52	5 months		1/28/2010 Email
3	RLS	Try taking Tonic Water or Quinine pills instead, I do not want the weight gain or the nightmares within 5 mins of FIBNA::Y drifting off to sleep!!!		F	50	1 days		1/20/2010
5	RLS	Some numbness on the bottom of my feet, between the 2-5 toe, but nothing inhibiting any activity. I found that when sitting on an airplane, if the rls started kicking in, I could take a mirapex, and within 20-30 minutes the symptoms were gone. It was a great help since walking around in flight isn't an easy task. It was only after taking mirapex that I was able to get a restful period of sleep at night...after about 15 years of complaining to doctors. My RLS started as I was going through menopause. That wasn't a surprise, because during both my pregnancies, I also had RLS symptoms that would go away as soon as I delivered. Of course, nobody called it RLS at the time...they just looked perplexed when I described the symptoms, and tied my feet with strips of fabric! for relief.	In August, 2008, I had to start a very aggressive cancer chemotherapy program, and the mirapex seemed to lose its ability to control the rls. I had to find other medicines to control it during that time.	F	68	6 years		1/18/2010
4	RLS	None	Wake more rested.	F	56	9 years		1/10/2010
3	Parkinson's Disease	Extreme weight gain 40+; sleeplessness; compulsive eating (espec. in middle of night); compulsive computer use; compulsive shopping; restlessness - need to be active; tired all the time, but can't rest; all of these behaviors are totally new to me - I don't like having these feelings.	I take mirapex in conjunction with stalevo and it has controlled the tremor associated with PD. I hate the side effects, but continue to take it because I don't want the tremor to return. I wish there were a natural alternative.	F	61	4 years		1/5/2010 Email
2	PLMD severe	Worked to help with sleep....but the side effects make it unacceptable. I have gained 30 pounds/ have obsessive need to keep busy....can't relax...edgy...irritable....am going to MD this week. This drug helped my PLMD, but has made me feel like someone I don't recognize.	Have been off/on Mirapex several times over the past ten years. Have reduced my dosage to 1mg. I could almost accept the obsessive cravings for sweets and the accompanying weight gain; can no longer accept the personality changes.....edginess....irritability....compulsive shopping/computer use etc.	F	63	8 years		1/2/2010 Email
1	RLS	Woke up groggy with the worst sinus congestion I have ever experienced; horrible headache and neckache; weakness in limbs; nausea.	This scared the heck out of me - I only took a very small doseage because I am so tired of RLS symptoms. I did feel, for the first time in years, my body totally relax and the RLS vanished - NOT WORTH IT! When I woke up, the side effects started. Thank God I found this website - I'm just now coming out of it - the half life time is about 12 hours for someone my age. I'm on my way to the health food store to see if there are any natural ways to help control RLS.	F	64	1 days		12/28/2009 Email
5	RLS	Very vivid dreams, but would not classify them as nightmares.	This drug has been wonderful for me. I now am able to cut the .25 mg doses in half, and combined with alcohol (which is probably not a great idea, but I'm a drinker) I always get a good nights sleep and no rls symptoms.	M	60	8 years		12/15/2009 Email
5	RLS	Before taking Mirapex, I never remembered dreams. Now, not only do I remember dreams, they are very detailed and vivid. In addition, I've had nasal congestion since starting the drug.	Mirapex has completely resolved my RLS symptoms. However, I do have to take it regularly (at the exact same time every night and at least 2 hours before going to bed) for the RLS symptoms to not occur.	F	23	3 months		12/4/2009
1	RLS	compulsive gambling! started mirapex on lowest dose it worked great but had to increase to 1mg. after about a yr. Then the gambling started and became gradualy uncontrolable. I have to try to overcome this terrible compulsion, I have a drs. appt. but not for another 2 weeks, I pray he can give me something else to relive the rls as it is the most miserable pain I'v ever experienced. I also have dizzeness, nausa, slight memory problems. But the gambling is running my life. Ican't deal with the self louthing as well as the finacial devistation after a binge (for lacke of a better word) I saw the warning this med causes but thought gambling,thats crazy. Take the warnings serious.	DO NOT START THIS DRUG!!!!!!!	F	57	2 days		11/18/2009 Email
1	Parkinsons	Compulsive drive towards non-typical behavior which seems to circumvent rational oversight and sense of responsibility. As a result, my wife is now considering divorce.	I would like to communicate with someone who has also experienced this compulsive drive to understand if your experience is similar to mine in the sense of how much conscious control we have or does it circumvent \ bypass the normal thought mechanisms. Your help could help me save my marriage so thank you in advance.	M	53	4 years		11/16/2009 Email
1	RLS	Severe weight gain 50+ excessive sleepiness during day, incontinence	Worked for the RLS but didn't figure out the problems I experienced were from the medication until I did research on the Web. I would never take this again.	F	53	1.5 years		11/12/2009
1	Brief User--Beware		Mirapex is a dopamine agonist. Dopamine is the neurochemical in your brain that , when hyperaroused, can cause OCD in people, exacerbate OCD in others (like myself), and cause rapid mood swings due to its short half-life. Dopamine is not a chemical of pleasure per se. It is actually a chemical in our brains that is used to reinforce positive experiences by hitting a high (as during orgasm) and then dropping to a low (after sex). By the up and down sudden rise and fall in dopamine, a person becomes "addicted" to the experience. That is why an orgasm is so addictive. Same with cigarettes and caffeine. I was fortunate in that Zoloft was making me dull after two years on it for depression. I took Requip in tiny amounts and it got me hooked on a new hobby (dopamine rise and fall)--World War II. I took Seroquel at night, which dampens dopamine a bit, and thus was able to adjust dose to finally allow my hobby to become part of my life without triggering OCD. Higher amounts of Requip brought back OCD--which comes from too much active dopamine. So, dopamine "rise and falls" are how we get hooked on things.	F	45	1 days		11/11/2009
3	restless legs	sleepiness, tired	I've tried every drug on the market, & mirapex costs more money, but doesn't do the job any better.	F	82	400 days		11/10/2009
3	RLS	Severe weight gain; memory deficits including short term memory and word retrieval issues. Attention deficit. Looking for any better alternatives. Any suggestions?	Wow! After reading this, I am definitely going to my doctor to get off this drug. I have been on it for 3 or 4 years. I have had terrible weight gain of over 35 pounds which I never would have attributed to Mirapex. I always weighed between 110-125 pounds which is good for my height but now weigh 160. It helped tremendously for the restless leg symptoms and when I forget a dose I cannot sleep well as the symptoms are worse then before I started. Also, I have terrible short term memory and word retrieval issues which after reading this forum, I'm beginning to wonder if it is the Mirapex. I also have trouble finishing anything and feel almost ADHD over the past few years. All of these symptoms have been only since taking this medicine.	F	49	4 years		10/19/2009
3	Re-Boost SSRI effect	The usual stuff at first: Sleepiness, followed by suicidal thoughts probably due to panicky feelings. Then I get hyper. Mood definitely stabilizes. It's just the jitteriness of the med that makes me feel uncomfortable.	Requip never made me feel jumpy like Mirapex does. I only use Requip a few days every couple of years to boost my Zoloft's response.	F	45			10/17/2009
1	RLS	paranioa.confusion,mental changes,sucidal thoughts,halluciations	i only took mirapex for five months and i had these symptoms and i almost killed myself because of the hallucanations and i cut my left wrist.luckly i did not die so if there is anyone with a story like mine please email me	F	33	5 months		10/15/2009 Email
4	Fibro symptoms, aches	Nausea, diarrhea, slight dizziness, difficulty sleeping, night sweats	I am on 0.75m of Mirapex or Fibro symptoms and have noticed both good and bad side effects. One the one hand, I have increased mental clarity and my energy levels are back up to where they were two years ago before I started getting sick. On the other hand, I have been waking up at night restless and sweaty. Two weeks ago I started to have diarrhea every day. Two days ago I started to experience the most intense nausea of my life. I have decided to stay at 0.75m and not increase to a full 1.0m At this point, the good outweighs the bad. I feel like my energy and personality are back for the first time in years.	F	28	3 weeks		9/25/2009
2	Fibro pain, RLS, mild muscle twitch	I started taking 0.25mg Mirapex(Pramipexole)Aug.21/09 (16 days ago). Prescribed dosage 3x per day. After two doses had tolerable level nausea. I did notice while on this meds. morning stiffness was definetely decreased that I was able to get up out of bed and get going after 20 mins. when it usually takes me 1 hr. After 7 days, I started to suspect strange reactions to Mirapex (e.g. increased pain from Fibromyalgia, headaches, waking up about 4x at night and then going back to sleep). Decided to keep taking meds 3x per day and tracked side-effects after each dose. I found that 4 hours after I take each dose my Fibro pain would increase to a Level 6 pain out of 10 Levels (pain pretty intense I would sometimes have to add 10mg Baclofen--muscle relaxant); the pain would stay intense for 2 hours then go away without any muscle relaxant. I believe this phenomina of increase pain/decrease pain is called on-off syndrome. I have never experienced this on-off side-effect from any other me	I noticed that Mirapex DID stop the muscle twitches that I had in my theighs and arms occuring approx. 8-10x per day. I have decided that I have given Mirapex a fair two-week trial period and really struggled with the side-effects hoping they would go away, however Mirapex has not worked for me. I found this website 11 days after I started taking Mirapex and kept in mind other people's comments. I was looking out for did I have this or that side-effects as another person. This website has been very helpful and comforting for me on my journey with this medication. --Andrea L.	F	46	16 days		9/8/2009
2	rls	Took .125 pill first night. What had previously been aching left calf suddenly all joints in body were impacted. Was awake every 15 minutes. Finally at 5am fell asleep. Had itchy chest. Doctor said cut back to 1/2 pill which I did for 2 weeks with no effect good or bad. Doctor is mad that I stoppped taking. Essentially said get out of office nothing more I can do for you	I recently started on Lipitor. We are questioning whether interaction of two caused strange reaction	M	62	1 days		8/22/2009
1		RLS	My husband has been on mirapex for about 12 years. He has uncontrollable actions. From fishing for hours,golfing, spending hours playing unline poker(morning, noon, night), shopping online, playing poker twice a week in our community, and now started driving 50 miles to a casino. What ever he does, he does it to the extreme and coversup and lies about the time he fill his addiction. The doctors just keep increasing his dosage. He falls asleep without warning, lies, mentally and verbally abusive, He can't just rest, he has to be filling one of his addictions. He now takes two or three 1.5 mg day. Along with 0.5 mg Clonazepam and prozac. (He just stopped the clonazepem, after a recent eppisode where he couldn't even talk.)It is distroying a 39 year marrage. HOW does he get off this terrible drug.	M	57	12 years		8/13/2009
3	RLS	Extreme nauseousness, insomnia, weight loss, uncontrollable shaking especially at night (though doesn't feel similar to RLS symptoms), loss of apatite, fatigue, numbness increased smoking, increased energy, better self-esteem and confidence, greatly lowered my neurotic depression though I am not taking this medication to treat my depression.	I've been taking Mirapex for over two weeks now. Started off at .125 for the first 5 days and then increased to .25 for the following 5 and then after that, .5 twice a day which only lasted a day due to the onset of the extreme side effects. My dosage is now lowered to .5 once a day a few hours before bed. Though not as extreme as taking the .5 twice a day, the side effects still persist. This medication has helped to GREATLY reduce my symptoms of RLS however, I am having concerns about the long term effects of taking this drug and am considering asking my doctor to lower my dosage back to .25.	F	25	16 days		8/6/2009
1	Parkinson's	Serious impulse control problems, hypersexuality, depression, craved risk and walking zombie sleepiness. Went from happily married to affairs, 800 sex chat lines, pornography and "massage therapists". Could no longer drive due to sleepiness. Lowering dosage and gradually stopping mitigated all symptoms.	While on this medication I almost completely destroyed my marriage and family. I was out of control. I became manic about sex. I am a respectable gentleman who had never even considered any of this in life. Now I not only have to deal with Parkinson's, I must repair a destroyed marriage and regain the of respect of my family and friends. I'm not young, I need and want my family and friends intact. The impulsive odd decisons I made in my business were costly. I am working hard to repair those problems. I am fortunate I did not harm anyone while driving with the sudden sleepiness. I fell asleep at the wheel many times. Mirapex is a frightening drug. Be careful and be very aware. The symptoms start gradually and you rationalize them away.	M	63	11 months		7/23/2009
3	RLS	Weight gain, increased sexual desires, RAGE, falling asleep while driving, aches and pains, RAGE, obsessed with death although not suicidal, confusion, RAGE, overall addictive behavior, tremers, balance issues, pain, and did I mention RAGE. My RLS is fine though. (.75 nightly)	Tried to quit cold turkey and spent two days flopping like a fish. The RLS came on like a f***ing bullet train over my entire body. However, even though I was so tired, the aches were gone. I'm back on it now and back to being a psycho. AND WHAT ARE YOU LOOKIN AT!!! Sorry, I just do that from time to time. The RLS is fine though.	M	39	10 years		7/22/2009
2	RLS	Use extreme caution . This medicine when I first took it worked like a miracle but over time I began needing more and more and more. Move over viagra... mirapex has me wanting sex all the time. However, I feel anxious for sex and can't get enough. I have a one track mind and that is when will my husband get home and we will have sex for HOURS and still I'll still want more. Other side effects include falling asleep at the wheel and this happens every single time. I have a huge craving for ice... I must have it even if it's zero degrees outside I will be chewing away on ice. I sometimes get nausea if I take too much. I also have memory issues as well as concentration problems. You have heard that sound of fingernails scratching a chalkboard and before mirapex it was irritating but now it literally causes my entire body to flip out. Explosive type anger. My tolerance level is almost non-existence. I can't sit still anymore. Always feel very fatigued but I think that is also due to my fib	KEEP AWAY FROM THIS MEDICINE...	F	48	3 years		7/18/2009 Email
1	Parkinsons	swollen splotchy red aching legs, insomnia, sleep attacks during the day even while driving,compulsive shopping,huge weight gain	I didn't realize that I should watch out for these symptoms and that they were caused by Mirapex. complained to many doctors about symptoms and only now got told (after many years of complaints)that Mirapex could be the problem. It is hell getting off of it, even slowly. after being on it for a long time. God help me get off of it. WOnder what will go away and what will stay because of the drug use for such a long time. For awhile I was even on 2 pills 3 times a day. The nightmares are horrific and truly real feeling. I have a tingling hand now nearly all of the time. Is that also from Mirapex?	F	56	8 years		7/15/2009 Email
2	movement disorder (unsure which one	(ERECTIONS, BONERS, WOODIES) popping up like crazy all the time. Didn't do shit for the stiffness and freezing but made me a horny SOB. This stuff is better than viagra in that department. I've had better success with cannabis(mixed with peanut butter between 2 crackers and baked). It relieves my stiffness and pain and lasts through the next day too!	Skip this crap and try cannabis(baked and ingested) for movement disorders, RLS and other neuro problems! It works better than opioid painkillers and muscle relaxers combined!	M	29	2 days		7/9/2009
1	RLS	Extreme Nausea, Chronic Headaches, Bizarre behavior, Compulsive behavior (started smoking flavored cigars and had to smoke them-- could not "not smoke them", Selfsihness, Change in mood, Change in demeanor, Change in personality, Anorexia, Anger, Sleep Disorders, Compulsive shopping, compulsion to drink, sompulsion to smoke and other addicitve behaviors	DANGER! DO NOT TAKE THIS DRUG UNLESS YOU ABSOLUTELY HAVE TO!!! My wife had moderate RLS and the doctor gave her a prescription of .50 mg. She has been taking it for 9 months every day once a day and she lost 35 lbs that she didnt have to lose-- she was already very thin. Her personality changed to being angry and down-- no patience with me or kids, etc. I watched helplessly as the woman I love and adore changed into somone I did not know. She started smoking flavored cigars and I have alergies to smoke, and cant stand the tast smell, etc. She would not even consider giving them up. I left. With some good advice from a friend I came back and asked some pre-thought-out questions to try and get to the bottom of it. MIRAPEX! This all started when she started taking mirapex for her legs? I was baffled. This drug nearly cost me my family, my wife and has cost me in other ways as well. She is coming off of it now and experiencing bad side effects (dreams, seeing things, pain, etc). DANGER! STAY AWAY FROM THIS DRUG!!	F	30	9 days		7/9/2009
5	Parkinson's Disease	Increased sexual desire. Odd behaviors of OCD and voyeurism. Manic behaviors with increased breathing, sweating, like on Speed. Can not sit still. Increased food consumption with junk food and drinks. Then within 3-4 hours drop like a lead balloon. Freezing and angry mood.	This drug is great for PD patients who experience freezing up and feel immobile. The side effects are horrendous and will cause tension, fighting, and inability to be aware that one's behaviors are bizzare.	M	58	1 years		6/30/2009
5	no			M	28			6/10/2009
1	Parkinson's Disease	Memory loss, headaches, increased feeling or tiredness, need to sleep more often and longer hours, increased desire to eat and at abnormal hours (middle of the night).	I am writing this on behalf of my Mother. She is 66 years old and began taking Mirapex for less than two months. Her first dosage was .125mg 3x's a day. Then increased to .25mg 3x's a day. Since beginning the .25mg dosage she has experienced memory loss (forgetting days of the week and dates), headaches, and feeling extremely tired.	F	66	45 days		6/7/2009 Email
1	parkinsons	my grandfather has parkinsons right now and he has been on mirapex for 8 years and he recently came off of it for various reasons. He is now experiencing panic attacks and has worse health issues. I would never recommend this drug to anyone. I have watched him become progressively worse and it is awful.		M	73	8 years		5/29/2009
2	rls	I've been having ankle and feet swelling beyond belief. My heels and ankles hurt on and off to the point that somtimes I can't even walk. I've gained about 14 pounds in about 5 months of using the drug. My face and wrists are very swollen as well. Not sure what to do but I know I'm waaaaay too young for these side effects. I've been having suicidal thoughts a lot lately as well. I know I would never act on these, but it's very disturbing.	Starting taking 6 months ago for rls. It was a life saver helping instantly once I was able to overcome the nausea. It works very well, however,the side effects are now affecting my quality of life and I'm finding I have to take the drug now early in the evening for it to take effect by the time I go to bed. This causes me to be very tired in the evening and has caused a lot of problems for me and my husband concerning intamacy. Like I said, I'm waaaay too young to have these issues. Don't know what to do. My rls is so severe that I have to take something.	F	36	6 days		5/24/2009
1	RLS, PLMD	I took Mirapex for several years and during that time my weight went up to over 270 pounds. I went off Mirapex for a year because I could not afford it and lost all the excess weight. Went back on it 2 months ago and have gained 15+ pounds. I didn't realize the Mirapex was the cause of my prior severe weight gain. The doctor never discussed it as a cause. After going back on and the sudden weight gain I did my own research and have since discovered this problem. I have a Dr appointment next week. I am discontinuing. Would rather use Vicodin!		F	47	4 years		5/19/2009
3	RLS	Worked on my RLS, which was a great releif after more than 30 years suffering and nothing else helping. Found had to take it 3-4 hrs before bed to take effect. Was not told of any side effects until started to wonder what was going on. Started out on .125 and had to increase to .375. Side effects kicked in at .25mg. Side effects include legs hurting upon awakening, muscle cramps that effect my walking, feet hurting all the time and MAJOR mood swings, OVER HEIGHTENED SEX DRIVE, desire for kinky/overt acts with wife, but find myself thinking about other woman all the time (never cheat and wouldn't), desire to pickup drinking and tabacco use that I have been 15 years without. Anger issues that I have alway controlled, depression/manic episodes, OCD type activities, suicidal thoughts.	Found this site and working on getting off Mirapex now!!!! Was wondering why my life was unraveling (I am a professional in the fire service and stable person) and getting worse the past 6 months (increased the dose to .375 6 months ago). Wife does not understand what is going on, even though I have asked her to read this site. Marriage may be on the rocks and not savable after 33 years, even if I get off because of my uncontrolled sex drive towards her and way I have treated her. This is NOT WHO I AM! Very frusterated right now. But hope is on the way now that I know what is causing it.	M	49	3 years		5/6/2009
2	RLS	I started this medication (mirapex) 2 days ago at night as told by my doctor to do. I have slept for 48 hours! I can sleep during the day any time I want. I have not had the RLS pains in my legs for some time but a sleep study showed that I was suffering from restless limb movement. Therefore I am tired throughout the day. Because I am on a lot of meds including heavy pain meds I no longer felt the pains and suffering from my legs at night.	I had no idea it would knock me out so much. My husband is very upset over this side effect. I have decided not to take anymore until I talk with the DR. which will be another 48 hours.	F	57	2 days		4/25/2009
1	Severe RLS	Chronic headache, diarrhoea, nausea and unable to get out of bed for over a week until I stopped the tablet	Within two days of taking the smallest dose of Mirapexin, I was confined to bed feeling more ill than ever in my life. I thought my head was going to burst, one sip of water gave me chronic diarrhoea and the nausea was unbearable. Never again.	F	56	10 days		4/13/2009 Email
1	fibromyalgia	weight gain, sleeploss, memory loss,obsessive/compulsive behavior,falling asleep during the day	When I first started taking mirapex I was happy with the increased energy. My dose was gradualy increased to 6mg at night. Over time my behavior became worse and I realised I had to stop taking the medication. I quit gradually with my Drs. orders. I have since had several bouts of severe depression and am still in the last one with strong suicidal thoughts/intents to the extent that mental mealth professionals are trying to get me hospitalised.	M	64	7 years		3/30/2009
4	rls	none		M	73	3 years		3/29/2009
1	PD	My husband (73) has had PD for 15 years. The neurologist prescribed Mirapex. It was the worse thing the doctor could have prescribed. He became a sexual monster.	The longer my husband was on Mirapex the worse the symtons became. He became very sexual aggressive and I feared for my life as he started raping me several times during the night. I could tell that he did not know what he was doing as his eyes were blank. It also made him confused and forgetfull. He could not remember what he did to me. After the medication stopped he was like a new person. When he took the medication he would have freezing spells and had many falls. He no longer shakes and walks much better no more freezing spells and he is much happier and alert. He also sleeps much better during the night.	M	73	3 years		3/29/2009
5	rls	slight fatigue during the day	take 0,25 mg at bedtime, additional 0,25 on long flights, and when I have to sit for hours. my life is almost manageable now compared to hopeless fatigue before. It works better for me than ropinirole (requip). I wonder about all the compulsive disorder comments byother users, if these were latent and the drug acts like a release.	M	52	6 months		3/27/2009 Email
1	Bipolar Illness	Extreme Nausea and weakness. Started by second dose. Stopped it was so bad. Mild OCD-like symptoms which have stayed. Certainly not worth the bother as it removed all quality of life that might be gained had it worked.		M	45	3 days		3/24/2009
1	RLS	3 lbs/month weight gain, shifted but not relieved pain in my legs, very vivid dreams. The .25 mg dosage is no longer effective. But I'm 9 lbs heavier and feel deceived by the doctor at the sleep clinic who should have clearly explained this common side effect.	I am so angry with Dr. Wright at the Minnesota Sleep Clinic who didn't warn me of the weight gain side effect. My RLS symptoms were so mild. Now I have to deal with this massive weight gain and the self esteem problems that go with it.	F	47	4 months		3/23/2009
4	RLS	NONE	VERY EXPENSIVE!!!	F	61	1 years		3/18/2009 Email
5	RLS	None whatsoever	has been completely effective from virtually the first day	M	73	10 years		2/25/2009
3	RLS, PLMD	Nausea, Weight Gain, Compulsive Behaviors, Exaggerated Movements, Sleep Attacks	Helped legs for a while. At higher dose, side effects worsened. Developed wild flailing movements that happened when not all the way asleep. Reducing dose helped all side effects except sick feeling in pit of stomach and daytime sleepiness. Do not stop abruptly! I did and it caused neurological problems. Wean off like it says.	F	58	4 years		2/23/2009
2	Severe RLS	Constantly hungry, most severe reaction after 2 years on drug is severe muscle cramps, feel like muscles in legs and feet are caught in vice for hours. Diagnosed with polyneuropathy.	Stopped the RLS syndrome, was a miracle, but now I am in so much pain from the polyneuropathy and muscle pain. I am not diabetic, no other cause for these symptoms can be found. I don't know how I will live with the RLS pain without this drug. Double edged sword.	F	60	2 years		2/17/2009
3	Parkinson's	I was diagnosed with Parkinson's disease in 2003. Started on Mirapex after one year. I became a compulsive gambler and gained about forty pounds. I have trouble sleeping all night and tend to eat while awake. I fall asleep during the day and have fallen asleep while driving resulting in several minor accidents. I've also had many close calls. The medication helps with my symptons but not sure its worth it. I will ask neurologist about other medications.		M	56	6 years		2/16/2009
3	Severe RLS	Weight gain of 20+ pounds in less than 1 year, bizarre sexual desires, very graphic dreams all night (i.e. animal mutilations, dreams that I am having sex with dogs, bloody horror movie type nightmares) - if taken too late (not given time to take effect) it actually caused me to be in a dream, wake up, and go right back to the dream - so that means my REM pretty much lasts all night. Obsessive buying - spent over $800 on sewing patterns and fabric I have never sewn, and scrapbooking supplies never used either. eBay mania. Muscle aches and pains, eye twitching, bad short-term memory problems (not good when you are a 911 dispatcher - I fear for my career	I began having RLS during my first pregnanacy in 1985, by 1988 I could not sleep at all and by that time had a second child who (now it is clear) also had RLS. I was diagnosed after a sleep study in 1995 after I had woken up cooking my bicycle helment on the stove, and constant suicidal thinking because of severe sleep deprivation. I was put on Sinemet which stopped working by 1997, I found out about Permax on the internet and asked to be put on that which worked, but was taken off the market in 2007. I drove sometimes up to an hour away to deplete pharmacies of their remaining supplies until I could no longer get it. I tried Requip and it didn't work for me. I started with one .25mg Mirapex (the Veterans Affairs pharmacies don't carry it because of the nightmares) now, 8 months later, I take six tablets. I have no choice. For me the relief from RLS outweighs all the hell of the drug -- that's how bad my RLS is to me.	F	45	8 months		2/4/2009 Email
1	RLS	OCD type behaviors, selfishness,Money mangement and overall personal worth diminished,Approx 40 lbs weoight gain in 4 mos,Massive appetite for sugar products,over all personality change, suicidal at times, depression, anxiety and loss of energy	Since on the drug wife has become very self absorbed and irrational,started compulsive shopping for items of no use,Began online chatting with strangers,Drove our company into bankrupcy,suicidal at times,very bizarre behavior which is unlike her since taking mirapex,Doesnt seem to have priorities in line like childrens welfare, house cleaning etc.Sometimes goes 2 days without showering,She also takes MS contin (morphine) for back pain in conjunction with this drug,	F	36	4 months		1/29/2009 Email
2	Parkinson's Disease	Anxiety, slight OCD	I am in the early stages of PD and was prescribed Mirapexin 3 months ago(0.36 Mg 3 times daily) because the PD was affecting my ability to work. I am a bass player and my right hand was not functioning properly. When I first started taking Mirapexin I thought it was a wonderful drug, my ability to play my instrument was improved 100%, however this only lasted a couple of weeks and I now have co-ordination problems again. I have never been a particularly anxious person, but for the last couple of months wake up in the morning feeling extremly anxious, not about anything in particular, just a general feeling of dread. I am considering asking the Doc if there is anything else he could prescribe for the PD because 1) Mirapexin does not seem to relieve my symptoms and 2) I cannot carry on with this awful anxiety.	M	59	3 months		1/22/2009
1	RLS	Nausea, diarrhea, lightheadness/fainting spells, headache, sweat and chills.	I've suffered from RLS for about 10 years. My doctor gave me a prescription of Vicodin to take--1 or 1/2 tablet before sleep to help with the symptoms--and a prescription of Mirapex. The vicodin has been working for, but I'm not too thrilled about taking codeine every night. So I tried Mirapex one time and believe me, I will never take it again. I felt as if I had been poisoned, and had all the symptoms of poisoning. I had alternate sweating and chills, diarrhea. I fainted twice when I got up to use the bathroom, and I threw up continuously for about 10 hours. Aside from the physical, I was very agitated and nervous. I did not have food poisoning because nothing I ate was different from what my family ate. I have never been so sick in my entire life. It was a horrible, horrible experience. If you have had side effects like mine, you are not alone.	F	29	1 days		1/18/2009
4	Full body nerve pain and fatigue	Unfortunate increase in spending for my favorite pastime, designing and selling jewelery. Manic behavior; force myself to go to bed at 3:30AM. Weight gain due to being awake 20 hours a day. Family mad at me all the time, would rather bead and shop than keep house and cook (go figure)	Taking it over 2 years, can't stand to quit due to return of intolerable fatique (too tired to breathe...head injury as a child) Would like to hear from anyone learning how to deal with changes in their personality. I enjoy the creative part of my brain being more productive but in this economy I need to sell more of what I produce in order to pay for the urge to design all the time...which, of course, requires supplies. I feel so much better that even 4 or 5 hours of sleep, which causes a different, common kind of fatique, is not enough to get me to go off of it. I could, it is not adictive in the usual sense.	F	63	900 days		1/16/2009 Email
5	rls	None that I can identify	I can finally sleep, am on lowest dose and take about 2 hours before bed....been on for 5 months and at last I am sleeping...after 12 years of struggling....does not work as well if one has alcohol in the evening or at dinner...but I am only concerned that after awhile the dose will have to be increased...I started by cutting pill in half and now need the whole pill.....	F	68	5 months		1/12/2009 Email
4	rls	none noted		F	56	3 days		1/6/2009
1	Restless Legs Sydrome	I started taking this drug in August 2004 weighing 140 lbs (5'8"). It worked miracles for my RLS symptoms. I experienced some augmentation, but was willing to live with it. By April 2004 I weighed 148 lbs, but didn't think to attribute the gain to Mirapex. By January 2006 I weiged 160 and in January 2007 173 lbs. That's a 33 lb gain in 2 1/2 years. I work out a lot and watch my weight, but still it's extremely hard to lose the weight. I have also had weird "spells" that neurologists think are partial seizures, but I think these are not seizures but altered consciousness from Mirapex. I also have developed a terrible short-term memory. I have a Ph.D. in philosophy. I've written three books and I'm very accomplished, so I couldn't understand how all this is happening to me. Now I think it's the Mirapex. The only other drug I take is synthroid, but only for the past few months.	I'd like to find some good alternatives to deal with the symptoms of RLS. Next I'll explore acupuncture.	F	48	4.5 years		1/5/2009
4	RLS & PLMD	I experienced absolutely no negative side effects from taking this medication.	I am currently taking .25 mg/day in the early evening of Mirapex. When I first started taking Mirapex, the first week was phenominal. All RLS / PLMD symptoms disappeared immediately, and I never slept so well in my life. However, like most RLS / PLMD medications, over time they tend to lose their strength, and it seems as if the RLS / PLMD symptoms find a way around the medication. I have currently been taking Mirapex for 6 months. Although it still does provide me with the benefit of lessening my symptoms and the rate of occurrence, my RLS and PLMD has found a way to fight through the medication. I have gone from no symtoms of RLS at the beginning of taking Mirapex to about 4 episodes per week now while still on Mirapex. It isn't the solution drug, but in my opinion, it does have a benefit.	M	38	6 months		12/15/2008 Email
2	PLMD	clinically documented constipation, severe unrelenting temper tantrums, OCD type behavior, sensory issues, difficult to wake up in morning, possible visual hallucinations	It was definitely causing terrible tantrums over trivial things, i.e. her pants didn't fit right or we were out of peanut butter. She had a terrifying hallucination this morning even though she has been off of it for a week. I could not take this drug myself, but have no memory of the time in which I took it. I definitely do not recommend this drug for people with mood disorders, either potential or diagnosed.	F	7	21 days		12/7/2008 Email
2		Severe weight gain, compulsive eating, twitching, fragmented sleep, waking up after several hours of sleep, nearly impossible to drive during the day	works ok for the restless leg, but I am now pushing 300 pounds, and can't seem to stop eating.	F	34	2 years		11/24/2008 Email
3	p.d	sleepless nights get stressed easy short tempered		F	60	7 months		11/15/2008
1	RLS	RLS	After the second night of taking Mirapex, my legs quit aching and I thought it was a miracle drug. Around the 3rd month, I developed a sudden extreme pain in my kbee, It felt like a knife had stabbed my knee. I cyt the dosage in half, and the pain stopped as suddenly as it has started. A week later, the pain was back with a vengenance, I no longer take the Mirapex, but my knee pain remains. Sometimes it is so bad I just want to scream. I no longer sleep at night- the pain keeps waking me up. The last couple of weeks I have had to move from the bed to the recliner halfway through the night to extend my leg to relieve the pain, My husband just rolls his eyes when I tell him I know the Mirapex caused these problems. I know in my heart that the nedication is to blame	F	52	3 days		11/14/2008 Email
1	RSL	Have taken for two months. Have gained 5 pounds due to complusive eating due to being constantly hunger; have very vivid dreams that seem real when I wake up. Very disturbing. I stopped taking the drug yesterday. Will write back in a month to report how my legs are doing.		F	59	60 days		11/9/2008
1	RLS	Mirapex initially worked, but overtime it exasperated my symptoms of RLS, thus my dosage was gradually increased over 10 years along w/the severity of the RLS symptoms. While on Mirapex, I had increased & chronic headaches, weight gain, edema, OCD, manic-depressive disorders, memory loss, unable to stay on task, impaired normal thought process and reasonable decision making process, restricted learning capabilities, obsessive spending on Ebay, and poor behavioral habits. I am convinced that while on Mirapex this drug cost me friendships, job promotions, respect in the workplace, and reduced my quality of life to a point of wanting to take it. This drug almost cost me my job and a very loving family, thank God I did not.	After learning of the side effects associated w/ Mirapex, I stopped using this drug. Initially my RLS symptoms were extreme & server, after about 4 weeks, these symptoms subsided and now my RLS symptoms or very minimal and controllable. The side effects that I was experiencing have drastically subsided or gone completely. It is my hopes that this drug will be taken off the market, and for no one else to have to endure this fate.	M	49	10 years		10/29/2008
1	RLS	I was saddled with headaches, foggy brain, and weight gain, while the Mirapex did not help my RLS. Upon quitting use, my headaches are gone, my head is clear, and I am once again losing weight!		M	48	4 months		10/24/2008 Email
1	Fibromyalgia	I started having severe twitching/spasming of legs & arms. At night, I would just be falling asleep and my whole body would spasm and wake me up. I also became obsessed with a game that was on my cellphone. I became paranoid and I had bizarre, vivid dreams.	It has been 3 - 4 years since I took Mirapex and I still have the twitching going on - though not as severely. Once I got off the drug, the desire to play games on my phone vanished. (I have never been a video game player.) This is a scary drug that impacts cognition. I'm amazed it is still on the market.	F	55	30 days		10/14/2008 Email
1	parkinsons	At first, it worked well, I could sign my name again and the tremors stopped. However, I had nausea, vomiting and fatigue, which I hoped would clear up in time. Instead, these symptoms intensified over the next 5 months. I was also experiencing increase depression and anxiety. I was napping 3 times a day and still sleeping all night. The first day I went off, I had amazing energy, no upset stomach and could eat chocolate again. The second day off, I did have some withdraw symptoms, like muscles aches and fatigue. These past. For me Miraplex goes on my list of evil drugs, along with Effextor.	For weeks my husband told me the problems were due to the Miraplex. I couldn't believe him. I think the drug clouded my thinking ability.	F	49	6 months		9/29/2008
3	Fibromyalgia	I talked to my Doctor about taking Mirapex after reading up on the pro's and con's of the drug. I wanted to get off soma and ANSID's that don't agree well with me. I am on a low dose right now. Since the first day I started the drug I have a very hard time falling and staying alseep. my eyelids twitch and wake up with an upset stomace. I haven't had wieght gain this far. I hope it stays that way. My PCP recommeded Lyrica and I didn't want to go on it for that reason. I do how ever believe I am getting a bladder infection. and do have a racing heart through out the day. I have been sweating. For the most part I rather be on this then other alternitives ask me in a month to see if i still feel this way. I don't want to increase the drug anymore, but I rather not be in pain. i am currently in school for medical assisting and I do also find it hard to get my words out since i began this drug, it's not bad enough to upset my GPA to much this far. But... i will let you know if i find it do		F	23	3 weeks		9/28/2008 Email
5	RLS	At first, some nausea and vivid dreams, dopiness after it kicks in (which is good because I can sleep!). Twice at the beginning, I suddenly almost fell asleep driving. That scared me but passed quickly.	Hugely effective. I used to wake up once an hour all night, now only once or twice. It worries me that after a month, I had to triple my dosage--suddenly when it wore off, my restless legs were 100x worse than ever before, could hardly sit down, arms just like RLS too. Is there a rebound effect? Will I need to keep increasing the dosage as I get used to it?	F	47	60 days		9/18/2008
1	restless leg syndrome	I vomited after about two hours and the medicine did absolutely nothing for my restless legs. I have severe RLS. It occurs every time I lie down. Klonopin has not worked and the only meds that have worked are Hydrocodone. I'm about to try Requip.		F	51	1 days		9/18/2008 Email
2	RLS	Relieved the RLS but started making me jittery at night, as if I'd had an entire pot of coffee before bed. Also had "hot flashes" during the day. Interfered with my sleep worse than the RLS did. For about a day it was ideal between relief from RLS and any of the side effects but after the third day of the higher dose in the sample pack I had to stop. Starter dose didn't do anything. Will be trying Requip next.	If the side effects weren't so bad, I'd stay on it but the main reason I need the relief is the RLS interfering with sleep. Daytime RLS symptoms are tolerable for now.	M	44	7 days		9/16/2008
5	restless legs	unsure since I am taking other medications such a blood pressure.Tremblings?/overall weakness?		M				9/13/2008 Email
1	Parkinson's	This drug causes compulsive sexual behavior. Twice it has cost me time in jail! Under un-watchward physician care and mostly from the use of this drug that was prescribed to me my my doctors. It has cost me two felony charges and 9 months in jail! It has cost me a small fortune, and my life has been nearly ruined. I can't recommend its use. Avoid it!	I feel that the company has been more than negligent in not warning the public or physicians properly of its dire effects on people, especially with a high suceptability to the adverse effects of oral medications. I was prescribed this drug twice by doctors(neurologists-so called), and twice in a very short time unbeknownst to me I began behaving in compulsive sexual way hughly untypical of myself. I ended up breaking the law and spent time in jail and lost virturally all I owned! I was living in a place where there were few people whom knew me well enough to properly detect that something was very wrong and that and inept "doctoring" and the very compounded effects of a very dangerous drug, -specifically MYRAPEX- I found myself in jail and a having become so compulsive in my behavior from the side effects of this drug that I became criminal in my lifesyle and mental state of mind. This drug is dangerous. The makers of MIRAPEX owe me big time! They taken no steps to comp	M	52	2 times		9/13/2008 Email
1	parkinson's disease	It started off slowly, but my neurologist warned me that it could happen. I experienced severe hypersexuality, Manic depressive behavior, OCD, gambling, overeating, sex phone calls, paranoia .... My life is turned upside down. Things got so bad I considered committing suicide. I drank and smoked pot to try and feel better, but it only made things worse. If you are young and taking this drug for Parkinsons ( I took 8mg a day.) STOP NOW. It almost cost me my life, my wife, my family and my job.		M	50	8 years		9/13/2008
2	RLS	Insomnia, running thoughts, brain fog	This medication was very effective for the RLS but at the price of insomnia. Expiriencing 1-2 hours of sleep a night, running thoughts all night, morning fog and difficulty concentrating. I was hopeful the side effects would lessen once I was used to the medicine but it only got worse.	M	42	10 days		9/11/2008
2	RLS	Very dizzy all day long. Just need to turn my head. Weight gain 20+ lbs in 3 months. Forgetfullness. Depression. Muscle aches.	I thought that the dizziness was my only side effect and it drove me crazy all day long. Everytime I turned my head I could feel my eyeballs bouncing back and forth. My husband didn't want me to drive anymore which was an issue with me. But I had also been gaining weight very quickly but thought it was from a depression medication I was taking. But I still continued to gain after stoping that drug as well. I have also been very forgetful to the point that I felt like I was losing my mind. Had some very embarrasing situations where I couldn't hide my memory loss. I have been having muscle aches as well and Im not sure if its from the drug or not but have a hard time getting out of bed in the morning or when sitting for a while. I feel so much older than I am. I have chosen to stop the Mirapex to see if I lose the side effects. It didn't help all that much anyway so the side effects arn't worth it to me.	F	42	3 months		9/9/2008
5	RLS	I have had no side effects from this medication.	Mirapex has been a life saver. I previously took Requip which worked for about 6 months, then my physician gave me Mirapex... I am taking half of the .125 mg in the evening. It takes a couple of hours to start working but my legs are relaxed which ables me to get to sleep.	F	53	3 months		9/8/2008
5	Severe RLS	Nausea, I was able to fall asleep quickly but was WIDE awake w/i a few hours. I became so sleep deprived that it started to effect everything,joint pain, sinus congestion, some depression.I have beentaking this med 2007.I have gained 52 lbsMy Dr. set me up for a sleep study that states that i breath just fine,But my heart range is 52 up to123. and that i sit up quite a few times an hour. I probaly woul'nt had to do th sleep study if I knew about all of reactions. I too am starting to gamble. I have neverbefore	I does a great job of controlling my severe RLS	F	44	2 years		9/8/2008
2	RLS	Had trouble sleeping, felt bloated all the time, constipated, headaches and it didn’t help the burning, tingling pain at all. Took .25 for 7 days then increased to 2 pills at night. Have not had more side effects but still have the ones listed above. And yet still no relief.	I just am glad I didnt have some of the really bad side effects that I read about on this site.	F	45	10 days		9/7/2008
5	Tremors	Impulse Control	Worked a wonder on my familiar tremor... however I became very obsessive compulsive.	M	32	4 months		8/31/2008
5	Restless Legs Syndrome	None that I can directly attribute to Mirapex	It is sad to read all the negative reactions, because Mirapex has been nothing short of a miracle for me. I have very severe RLS, (everyday, many times during the day/night, causing sleeplessness every night, most of the night). I take .125 mg (the minimum dosage), at about 8 p.m. and it continues to be effective, taking about 2 hours to "kick in." When I am going somewhere requiring me to sit (concert, movie, etc.), I take it about an hour before the event so that I know I will be able to sit through most of it.	F	60	5 years		8/23/2008
4	Restless Legs	Pain in legs and feet, Obsessive Thoughts, Obsessive eating, extreme lethargy, morning hangover, Sleep is all I think about.	Completely stopped severe RLS symptoms, complete lethargy not worth it though.	M	39	30 days		8/15/2008
4	Parkinson's,Dystonia,RLS	Mirapex works well for my symptoms -tremors,dystonia,stiffness,etc. My main complaint is the weight gain of 35lbs in 2 years. If I sit down, I am ready to fall asleep, but at night, I am wide awake. I generally sleep from 3am to 7am. I tend to be foggy, but it may be sleep deprevation. I make sure to take it with food. I don't eat much during the day, but binge after midnight. I also am compulsive about computer-games/research and shopping at Thrift stores. I have managed to fill up most of my horizontal surfaces with vintage pottery. It works well for me, but I may have to switch drugs due to the weight gain.	Works great for me.	F	56	3 years		8/15/2008
1	Restless legs	Hives, itching, poor sleep, but the worst thing was the deep depression with paralyzing sadness and a feeling that my heart was breaking.	I am so glad I figured out that it was the Mirapex causing my depression. I was almost ready to go back on Effexor when I decided to just stop the Mirapex instead. I felt better in one day and, after two day off of it, I feel fantastic. I still have the RLS, although it has gotten better as I get my ferritin level up. In the case of Mirapex for RLS, the medicine is worse than the disease. At least with RLS, once I get to sleep, I sleep well. With Mirapex, you wake feeling like you haven't really slept, which might be what causes the depression. Lack of sleep shrinks the amygdala, the part of the brain that processes emotion, and small amygdalas are linked with depression.	F	51	5 weeks		8/9/2008
3	RLS	Have been taking Mirapex for approx. 2 years. I thought I was crazy until I read these comments and I see so many similarities. I have severe muscle pain and weakness, the sensation of something brushing against my arms and legs, tapping my teeth, constantly moving my toes,neck pain, inability to sleep, nausea, increased interest in shopping although not excessive.	It has definitely helped the RLS but I am going to find an alternative treatment.	F	60	2 years		7/31/2008
1	Parkinson's disease	Manic behavior, compulsive gambling, binge eating, swollen legs and feet, insomenia--this drug has ruined many, many lives. Be very careful!	I know of a doctor, several attorneys, a nun, ministers, bankers, policemen--all of whom have had their lives ruined by this drug and the manic, compulsive behavior it causes. It is time for Boehrilnger Ingleheim to do the right thing by these people whose lives have been devastated. These people's suffering has spared someone else from enduring the hell that Miarpex can cause. Beware! I never thought it could happen to me, but it did. Remember that this is a medicine that affects your brain!	M	61	5 years		7/27/2008
3	RLS	Anxiety, lethargic, low energy especially in the AM,paranoia, a need to go back to bed after being up in the AM for an extra 20-30 minutes,memory loss, weight loss, dry mouth,ankle & hands swelling, lower motivation. AM hangovers.	The side affects took time to develop and became much worse the second year. My sleep has become deeper and slightly longer, 5.5 to 6 hours. Minimal S/S of restless legs in the evening. Falling asleep early in the evening.	M	70	2 years		7/19/2008 Email
2	restless leg syndrome	intense, weird dreams; increase in anxiety, morning 'hangover', constipation, profuse perspiration and night sweats	It certainly fixed the itchy-twitchies in my legs but the dreams were disturbing. I take a low dose of Zoloft for pre-menstrual dysphoria and this drug seemed to work against the beneficial anti-anxiety properties of the Zoloft. All in all I'd rather have itchy legs - will try homeopathic remedies, up the iron intake. This drug just made me feel too weird!	F	48	15 days		7/14/2008
3	RLS	Has radically altered my sleep patterns. Before taking Mirapex my lifelong sleep pattern was difficulty falling asleep (often 2-3 hours), but then sleeping through the night afterwards. On Mirapex, I can fall asleep very quickly at night (as well as during church, in meetings, watching TV or in Movie Theatre), but generally wake up at 3-4am and can't go back to sleep. Have also had a lot of sticky phlegm in throat that stated about the same time as starting mirapex, that contributes to snoring and waking frequently at times. Have also seemed to have struggled more with some compulsive behaviors (primarily eating) that may be related.	Mostly controls RLS symptoms.	M	45	18 months		7/10/2008
3	RLS	Nausea, sleeplessness	I'm taking .125 (I think) as needed. It does knock down the twitching, although not completely. The nausea the next day ruins it for me though. Since I don't take it regularly (perhaps once a month or even less), I don't suffer from the other side effects mentioned.	M	45	2 years		7/7/2008
5	Parkinson's Disease	Vivid dreams, occasional brain fog	I have had Parkinson's Disease for 7 years. Including DBS, Mirapex (1 mg. 3 x day) is the first drug that has stopped the tremor and given me back a mostly "normal" life. I take it in combination with Amantadine. I was shocked to read the reports in this column. My experience has been positive.	F	60	1 days		6/28/2008
5		Nasal stuffiness withing 30 minutes of taking it. Sleepyiness after taking it, plus need to sleep about 2-3 hours extra a night. Possibly loss of focus during the day.	It has truly been a miracle for me. It has given me my life back. I had severe RLS for 25 years and suffered about 12-15 hours a day.	F	44	12 months		6/27/2008
5	RLS	Insomnia	I had terrible pain and discomfort every night from RLS, I would even have leg shaking during the day. Mirapex has been a wonder drug for me. I tried both Mirapex and Requip and I found Mirapex to be much more effective.	F	43	6 months		6/20/2008
1	Parkinson's Disease	Taken by my 88 year old father. Developed insomnia - awakening at 3:00am, compulsive eating - upset his diabetes control, compulsive repetitive behaviors, severe swelling in feet and ankles, hallucinations and irrational behavior.	This was a nightmare!!!! He never did work up to a maximum dose, his symptoms and behavior got so bizarre, we insisted the neurologist wean him off this drug. He is still recovering from the damage done by three months of Mirapex!	M	88	90 days		6/13/2008
4	RLS	Slight upset stomach mid morning, taking medication around 9 pm. I understand others began clenching teeth at night. I am also aware that I am doing that. The bad taste in my mouth also occurs. I really don't like any of these side effects, but the bad taste in my mouth bothers me mosts.	I have been experiencing lots of forgetfullness to the point that I could no longer cover it up. It was affecting having coffee with friends, remember lunch dates, appoints, etc. It became clear that I could be experiencing sleep deprevation. As a result my doctor and I explored the idea that I had RLS. I couldn't watch late night TV I would begin to move my legs as they felt like I was experiencing "growing pains" as I did when young. Turns out that I had not been experiencing REM sleep. I have not dreamed in years. I was up multiple times during the night thinking that I must have heard a noise that woke me but it was angst in my legs that nearly kept me awake all night. Not wonder I could not function during the day, or rather remember most of what I should. I was sleep deprived. Now I sleep more that 4 hours at a time and I actual have dreams. Dreams are a good thing. It means that you are getting the REM sleep you need to survive, although I am not an expert,	F	52	4 months		6/5/2008
4	parkinsons	hallucinations,		M	56	4 months		5/30/2008
3	RLS	Gained 60 pounds since taking Mirapex March of 2007, COMPULSIVE shopper, I owe $20,000 in credit card payments, binge eating, addicted to chocolate, severe sores and rashes on my arms for over a year, haven't slept an entire night, I wake up every few hours, tired all of the time.	The requip that I had been taking for RLS hadn't worked anymore, so my Dr. put me on Mirapex and it was right after I begain the drug that my arms starting breaking out. I walk around on the hottest of hottest days in jackets and anything long sleeved because I'm so embarrassed ofmy arms. DOES ANYONE KNOW OF ANY OTHER MEDICATION FOR RLS THAT WOULD WORK, I'M DESPARATE. THANK YOU. RESTLESS IN SARASOTA	M	55	15 months		5/26/2008 Email
1	severe rls	tics in eyelid lasting about 3 weeks. Ongoing tearfulness and unexpected crying at work. spending spree can not emphasis the problems this side effect has on daily living. Eating benge cant figure out why I am eating and have wieght gain and water retention. Hypersexuality (controlled but exessive for this patient and unwanted due to unmarried status) too much flirting.No gambling but other problems are similar to gambling and risk taking. Calming effect translated into lack of concern for daily routines such as bill paying and work requirements.	I sleep much better. I quit some of my activities(reduce stress) and will discontinue its use immediately.	F	46	4 months		5/24/2008 Email
3	RLS & Parkinsons	I have most of the side effects mentioned: Constipation, overwhelming sadness, binge eating weight gain, headaches ( Migrane) agitation, teeth clenches, awake after 4 hours sleep, severe edema, drowsey abour 45 _ 60 minutes after taking meds, memory loss, joint stiffness, increase in tremors, shortness of breath, clumsey, toe cramps, drooling, light headedness, feeling "wired", fidgity all the time, can't "settle" down, severe emotional hypersensitivity and crying spells daily, obsessive compulsive, gambling issues.	I have been on Mirapex for about 8 years, very low dose at first for RLS, then diagnosed with Parkinsons and dose increased. Moved to Nevada and doctor didn't know what to do with me and INCREASED MY DOSAGE. I now take 12 mg a day....plus 8 mg of artain a day. Just last week ( May 9) went back to original doctor with the above list of issues ( I thought I'd had a stroke) and he was shocked that I am taking the dosage that I am. He is slowly taking it down and hopefully most or all of my side effects will leave also. I do have to say that it has greatly helped my RLS, don't know about the PD, since now all is masked with side effects. I don't recomend it to anyone, and yet, I feel I have some relief from RLS.		58	8 years		5/11/2008 Email
1	RLS	I am writing on the behalf of my mother whom has nearly lost her mind because of this drug.It is very dangerous! Unaware of what she was doing my mother became an Obsessive Compulsive Gambler.She has lost over $500,000 in the last year.It wasn't until the money was gone and she was off her medication did she relize what she had done.By then it was too late.Now my mother owes the IRS a lot of money and they don't want to here about what Myrapex did or did not do.She has lost her home and probably most of her children.What make this even harder is that my dad died for the money that she gambled away.	I have not heard of this medicine causing this side effect until my mothers Rhumetologist told her what it was doing to her. He noticed the changes in her from the moment she started taking it and he discontinued the medicine.The OCD brought on by this drug does not appear to effect people with Parkinsons Disease as it does those whom take it for RLS. I wish everyone the best and I hope your story does not end like ours.May God be with you.	F	39	1 days		4/29/2008 Email

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Average rating for drug: 3.0. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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