WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression and anxiety Weight gain, constipation, insomnia. Wellbutrin SR (150mg, twice daily) worked great for the first year and in combination with 10 mg. Pamelor in the evening. However, despite working out like crazy, I gained about 20 lbs. The cravings are impossible. I got off the Pamelor 6 months ago and the insomnia returned, but the weight stayed on. I then weaned of the Wellbutrin and my insomnia and constipation went away, AS DID MY SEX DRIVE, but the weight INCREASED FURTHER. Despite all this, my depression and anxiety did not return, but I am feeling irritable and annoyed. I think all ADs should be avoided unless somebody is suicidal or very severely depressed. Doctors prescribe these things much to quickly. If depression/anxiety are bad then go on the stuff for 6 months to a year, but combine with very, very serious physical conditioning, mental stimulation (i.e. something mentally challenging), and 'forced socializing'. After 6 months get off and just stick with physical conditioning. In the long run, this stuff screws M 43 18 months
11/13/2008
 3  mild depression, mood swings Days 4 & 5, no side effects. But on day 6 I was very constipated. I counteracted it with a laxative. Have had a headache and upset stomach for the last couple of days. F 43
150mg 1X day
1/13/2011
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Patient History
 2  Panic Attacks My Doctor prescribed Wellbutrin for "panic attacks"...turned out I had Arrythmia which needed to be corrected by an ablation procedure. Wellbutrin caused many side effects and did not help my arrythmia. I would caution those who think they have panic attacks that it may be arrythmia which is completly different although the symptoms are the same... M 43 1 months
8/4/2006
 2  Depression, snappiness, inattention Insomnia, angina (chest pain), tachycardia (increased pulse), weird heart sensations I took 100 mg once a day for about 2 weeks. On the plus side, I concentrated and worked way better than without it. On the minus side, I couldn't sleep without a benzodiazepine, and had problems with my heart: rapid pulse, chest pain, and weird heart sensations. Have your heart checked with an echocardiogram (not EKG which is junk) before starting this medication. If your heart, like mine, isn't strong, don't take it because it will mess up your heart. Also start at the lowest dosage and once a day only, and increase, if need be, after 1-2 weeks. M 43 2 weeks
3/24/2007
 2  depression clenched jaw, insomnia, racing heart (all went away eventually) Continual effects were ringing ears, weighloss, crying, EXTREME ANGER/RAGE I could deal with all the side effects except for the RAGE. I've lost relationships with friends, family members and boyfriends because of my uncontrollable anger. Luckily I've never hurt anyone. I no longer take wellbutrin (or the generic, been on both and symptoms are the same). I've gained back about 15 pounds but I'd rather be heavy than ANGRY and possibly in jail for hurting someone. I've wasted thousands and thousands of dollars, and destroyed relationships with really great people because I thought (and THEY thought) I was CRAZY. If you decide to take wellbutrin or bupropion, please be very very careful! If the anger and rage is out of character for you, don't let your doctor tell you that you just need more therapy: it's the DRUG not YOU. F 43 4 years
5/22/2007
 2  Clinical depression Light headed, brain fog, headache in my eyes and fatigue. Maybe i should give it more time. 43 2 weeks
100mg 2 X
11/18/2015
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 1  Severe depression At first I was so down that I was happy for any pill to do ANYTHING to help me. But I noticed after a few weeks that I was still depressed, although less so. I figured I'd wait a few more months. Well after 8 months of taking it, I can tell you now that I have never been so angry and raging in all my life. I thought it was me. I did not think it was the pill. I nearly lost my relationship as a result of the Wellbutrin's effect on me. After doing research and speaking to my doctor, I found out that Wellbutrin is known to cause irritability and in some cases intense feelings of anger and extreme RAGE. I mean the kind of RAGE where you feel like something has totally gripped you during the time you're raging. I now am off Wellbutrin and am on Lexapro. I would not suggest Wellbutrin if you're prone to any kind of irritability. I also could not sleep b/c of the medicine. For months now my sleep has been interrupted and it was very hard getting to sleep. Doctors won't tell you about the RAGI If you want to quit smoking, then it's a good fix for that but not for really severe depression. I took Wellbutrin in two separate time periods and the RAGING and crying fits happened all the time. F 43 8 months
7/11/2007
 1  chronic fatigue, anxiety, irritable out of control, restless, heart racing, anxiety Wow! I have been on several anti-depressants trying to minimize fatigue, anxiety and irritability. I had only tried this for a week, but could simply not take it another day. I, too, felt like I was losing my mind. Especially at night, my heart was racing, my body felt jumpy and I was so restless that I could not go to sleep. Also, I felt very, very irritable- even more than before and very anxious. I wished I had never tried this drug!! F 43 7 days
6/13/2007
 1  Depression Seizure (grand mal) I started off 100 mg daily for 3 days, 100mg 2x day for 3 days, 150 mg in a.m. and 100 mg in p.m. x 3days, 150 mg x 2 day....on the 5th day of 300 mg I had a grand mal seizure at 9pm. Luckily I wans't driving but on a dinner cruise. I bit the side of my tongue as well as urinated all over myself. My bf said it lasted about 40 seconds. My CT scan at hospital was normal. However I just had an EEG test yesterday and the neuro said it showed abnormalities on left side of brain. I have to go back in a couple of weeks to retake it as well as a MRI. I'm so scared of having another one! Anyone else out there this happen to? My last dosage was Saturday 12pm. Prior to wellbutrin I took effexor for a couple of weeks and I broke out with itchy bumps so I had to stop taking that. Prozac and Celexa didnt do anything for me. F 43 2 weeks
150 2X day
8/4/2011
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 1  Depression Rage, anger, some difficulty sleeping, vivid dreams Incredible long-lasting orgasms.....better alertness then Lexapro, able to function well on 3-4 hrs sleep. Didn't do much to stop hunger. M 43 14 days
125 1X day
7/17/2012
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 1  anxiety Taken with 1mg. Klonopin. Metallic taste in mouth, sensitive gums, attempted suicide (stopped taking after waking up in hospital after overdose - had 4 drinks night before)After I came home from hospital, Husband and daughter stated they didn't like the was I was for the past 30 days, they could not explain it, stated I acted weird/funny. I went to Dr. for Anxiety... After seeing her yesterday(3days after hospital release), she even went over my records and repeated that she wrote "Very upbeat" - so why was I put on a antidepressant?? Now she states I probably have Type II Bipolar & wants me to take something else!! Very Leary.... F 43 45 days
150mg 1X day
5/18/2010
 1  depression emotionally removed , lack of sympathy/empathy, decreased appetite, twitches, facial muscle spasms, SEIZUERE ... Not sure if this medication actually helped more than it hurt. I functioned but, as a mom, I dont think the price to my family is worth it. Compassion and empathy sort of fall by the wayside..If a dose is missed, lethargy sets in quickly..so meds have to be taken on schedule... Ultimately I took all 400 mg at one dose , instead of spreeadung it out over the morning and wound up hospitolized from severe seizure.. woke up on a friends couch to ems, w bleeding mouth from biting it and my tongue, memory loss, unable to id the year or president or my friend by name or otherwise..very scary.. hospitolized for 2 days..very foggy for days, and muscle cramps.. seizures are no fun. stopped immediately F 43 6 months
400mg 1X day
5/19/2010
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 5  Anxiety, depression weight loss, some shakiness, some insomnia I had packed on weight while taking Paxil and Zoloft, but I'm smaller now than I have been in years(size 5-7). I don't need to sleep as much as I used to although I still feel tired sometimes. F 42 8 months
7/30/2001
 5  Anxiety depression This has worked great for me and solved anxiety as well as depression. Lost a few pounds. Side effects only lasted first few months. The XL 300mg gave me anxiety could not tolerate it. 150mg SR am and afternoon work great. Will be long term user of this. Tried others Effexor felt so off and confused. Celexa good but gained 20lbs F 42 4 years
150mg x2
1/10/2013
 5  depression, anxiety a common swelling of jaw leading to biting inside of mouth (ouch!), slight agitation, dry eyes, increased urination, occasional insomnia if i also have caffeine. Many of the side effects that I had when I first took wellbutrin SR (appetite reduction, shaky hands, intensely dry eyes, dry mouth, stomach upset, skin problems) were completely 100% GONE suddenly after 12 months of taking this med. I don't quite know why it took so long to adjust, but there are reports of side effects fading after many months, so don't ever rule that out. Also, we all have to always consider that it might be the illness that is giving us various side effects (intense stress does crazy things to the body). Often we just need a lot of time to let our bodies adjust, and we may have to make other adjustments ourselves, such as changing diet, exercise, etc. I have more or less chronic anxiety, but it comes with yearly or so bouts of mild-moderate depression. 100SR is enough to eliminate the depression as well as more severe feelings of anxiety within a week or two. I also get panic attacks periodically, and believe it or not, wellbutrin SR completely eliminates these, which proves that you don't necessarily need a sedating med or SSRI to manage panic problems. I highly recommend to try to start w/ a LOW DOSE at first, such as 100 SR ONCE a day, not twice, and then move up to 150 SR once a day if needed. Some of the more common side FX on this board go away with reduced dose. For me, even the difference between 1 x per day or 100 SR and 150 SR is a very big difference & I often cannot tolerate the 150 SRs. I have also tried the XL version, which has much fewer side FX, but the extended release keeps me up nights, so that is out for now. I have taken this med on an off for the last 8 years and it is very helpful. There seems to b F 42 9 months
3/25/2007
 5  Depression/Anxiety attacks/insomnia Other than a bit of constipation, dry mouth, and nervousness for the first few days, no negative side effects. I have noticed that I'm less timid about speaking my mind and when I feel the "fight or flight" urge, I'm much more likely to fight. I don't consider this a negative side effect. Positive sexual side-effects. Since the age of 14 I've always been slightly depressed (on and off). After a series of disappointments and several huge life changes, my system became overwhelmed and I eneded up in a deep depression for about 3-4 years. About a year ago my Dr. prescribed 25 mg. of Pamelor every evening (and Xanax as needed). It significantly improved the depression, somewhat improved the insomnia, and the anxiety subsided somewhat. But I still didn't feel on top of things, my energy and motivation were a bit down, and I had gained 10-15 because of a greatly increased appetite. So overall, Pamelor was very good, but not great. My Dr. gave me 150 mg Wellbutrin SR to take every morning, in addition to the 25 mg Pamelor every evening. What a great drug!! I don't just feel on top of things, I feel better than I ever have. I feel like there is nothing that I can't deal with or get past. My confidence is soaring. It wasn't really too much of a problem before, but these days I want more sex and bet M 42 2 months
3/28/2007
 5  Depression side of bipolar feel revved up, shaky hands, nasty taste in mouth all the time, caffeine is too much now and puts me into anxiety mode, take a klonepin now and again when the energy from the Wellbutrin is too much Lifted my depression within days, actually could feel it working. More energy and impulse to do things, sleeping nice and regularly in spite of extra energy. I take my second dose of 150mg at 4:30pm which helps. I've used this over the years and it is my good old standby. Different side effects each time but nothing bad enough to stop. The nasty bitter taste is kind of a drag though--that's a new one for me. My suggestion, once you feel better for a month or so, taper off this drug. Don't take it for years! F 42 23 days
6/1/2007
 5  Depression/ADD A little sleeplessness in beginning, but then virtually none I love Wellbutrin. A nice side-effect is also that it reduces food cravings. Works great for ADD. Without it, i lose focus. My mom was on it briefly and couldn't tolerate it, unfortunately. Made her constipated. One drug I want to caution people about is CYMBALTA. It works great for depression, but there are side effects you should look into before going on it, AND IT'S A NIGHTMARE TO GET OFF OF!!!!!! Please look up comments on Cymbalta before considering it. Best wishes for mental health to us all. F 42 14 years
3/19/2009
 4  depression Short term memory loss The only side effect I have noticed in the last few years is memory loss. My dosage is 300mg SR daily. At first I chocked it up to stress but the memory loss has gotten worse. This seems to only have effected my short term memory. I forget things that have happened only moments ago. Like this morning in the shower, couldn't remember if I had washed my hair or yesterday on several occassions I was told things or handed something but couldn't remember. A few months ago while driving down the road I forgot what city I was in. This was a horrible feeling. Now this is a daily occurance for me and yes, it concerns me greatly. This is a catch 22 for me. The wellbutrin has helped me deal with life and enjoy it much more but now my short term memory failure is bother me greatly! Not sure what I will do about this but for now I am staying on the wellbutrin because I don't wont to go back to where I was. 42 9 years
2/1/2009
 4  smoking tinitus late at night - constipation (which means eating less) - not being able to peak like i did when exercising before the drug. early onset of menses. i stopped smoking months ago - but was all nicotined out with patches, gum, and lozenges. it's helped with the nicotine cravings but hasn't squashed them. hopefully - i don't get the rash. not as much sleep but still being cogent and coherent the next day. the 'euphoric' feelings of day 3-5 is long gone. F 42 15 days
2/14/2006

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