TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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 DNA DAMAGING DRUGS

 Type: Rx Drug

  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  BC-Trip Neg-Stage 2A Joint and muscle pain, night sweats, fatigue, migraine. F 52 2 months
2X M
3/5/2013
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 3  Breast cancer Stage 3A I was just diagnosed last year MAY 2010. I can admit I am still alive but living in a body that feels like I am 90. I wake with such horrific pain I have to take my Morphine 30 mg instant release and 60 mg slow release. It takes about 1 hour to feel well enough to get out of bed, just to go to the couch, I can hardly stand for 5 minutes, I cannot climb stairs well, use handicapped parking areas to avoid walking so far, my legs feel like they are on fire. They pinch, burn, throb, ache, with pulsating pain and sometimes shooting pains. I can have a massage but as soon as I am finished they hurt equally to when it started. I have found a scalding hot bath helps until my morphine kicks in and takes the edge off enough to sleep. Since the taxol I have become an insomniac. I dont sleep well or at all with out the help of 2 sleeping aids. My arms up to my arm pits ache when things get really bad. Also I believe A/C first contributed for my hair loss but I am sure taxol didnt help because abou I too wish I would have known about these side effects. I noticed the extreme "I cant take it" kind of pain right after my 2nd dose of taxol, Where as A/C just made me feel like I had been hit by a bus and I was nautious the entire time. Those symptoms started the 2nd day after treatment and lasted until about day 10. Things were the very worse at about day 5 through 9. My quality of life is ruined. I used to work managing large hotels and was used to running around the building to manage things. I excercised regularly and lifted weights. I loved rollerblading and biking. My feet go numb after an hour of wearing shoes.I cannot keep up with my 3 year old. I am unable to work, not even able to depend on myself to wake up in time, since I dont sleep well, All I can say is without the morphine I am on, I would rather die than feel the extream intense pain I have when it isnt in my system. I have tried to go off of it many times but the pain is so horrific. I am looking for someone else like me, in my situation. I have tried ketamine infusions which they said will reset my nerve path but even that, which was helpful, did not work. HELP!!! F 31 2 months
2X M
12/13/2011
 3  Fallopian Tube Cancer Severe neuopathy in hands and feet/toes. Loss of taste, dry mouth, inflammed veins, complete hair loss, and nausea. Due to the level of my neuropathy, my doctor took me off of the Taxol after the 3rd treatment. After a few weeks, some of the symptoms did subside and my hair did actually begin to grow back(not that this was my main concern), after 6 weeks. Everybody is different, but I will say that the recovery period after each treatment without the Taxol was reduced by about a week. F 47 2 months
1X O
5/29/2011
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 2  Triple negative breast cancer Numbness/loss of sensation in fingers and toes; no sense of taste, so food seems disgusting; awful, bitter coating in throat; 3 days after treatment bone/muscle pain starts and lasts for 4-5 days. Worst in the hips, lower back, and knees, but also shoulder bone and ankles. I hobble around like a 90-year-old, just as many of the comments above mention! Did 4 rounds of A/C followed by 4 rounds of Taxol--the last round is later this week. My onc said that since I tolerated dose-dense A/C so well, Taxol would be a breeze. Well, it's different from A/C but I wouldn't call it a breeze. I sure hope that this was worthwhile, but I guess that only time can tell. F 49 2 months
2X M
3/15/2010
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 1  Breast Cancer I had a stage 2b breast cancer. Taxol resulted in an 8cm abscess in my lung. I had anemia. It was discussed on my second treatment if I should have a blood transfusion, and not have the second treatment at that time. I was given an injection of medication that was supposed to increase my red blood cells, and then given a taxol treatment directly after given the. I believe that this treatment resulted in the lung infection, for I had a low grade fever for several days following this treatment. Despite, complaints about feeling ill, treatments continued. Throughout the treatments I was developing pain in my feet and hands. I was told to take large quantities of vitamin B, which I tried. I developed peripheral neuropathy that continues to the present, 5 years after treatment ended. In fact, over time it got worse until finally I couldn't walk. I was told it wouldn't last but tests show I have no reflexes from my knees down. I finally was given neurontin, by a physiatrist, which w I think if I had a stage 4 breast cancer, I wouldn't be as angry about the resultant deterioration in my quality of life, and would have seen it as it as saving my life (many people have said "well it saved your life"). I know there were other ways to go, with regard to chemotherapy, which I only found out after the fact. I don't believe it was necessary for the stage of cancer I had, but would definitely not have felt that with a stage 4 cancer. I checked off dissatisfied but that was with regard to having a stage 2b breast cancer. I do understand that not everyone has these side effects, but for whatever reason I do, and thus the anger and frustration. F 62 2 months
6/6/2009
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 4  Stage 4 lung cancer Slight neuropathy and swelling of feet; slight tingling of fingertips; almost complete hair loss including all body hair. Side effects not suffered include nausea, intestinal problem, heart or kidney problems. I have had 20 injections (each lasting 2 hours) of Taxol in the last 26 weeks. I take 3 weeks in a row, skip a week, and then start another 3 weeks of injections. Currently I will be skipping 3 weeks (impending cataract surgery) and resuming weekly injections on June 13th. I have found that this skipping allows my body time to rebuild and not leave me completely drained and weak..The day of and the day after chemo are my coming down from the steroids days. Days 3 and 4 after chemo are generally my "don't do anything" and rest days. Days 5 and 6 are my "normal" and productive days. The latest CT scan shows that Taxol has reduced the cancer mass in my lung to one-third the size it was before Taxol. Prior to Taxol I was on Carboplatin every 3 weeks, however this chemo still allowed for the effusion to build up in my lung. Since starting on Taxol last November I have not had the need to have my lung drained of effusion (thoracentisis). As a comparison, between my diagnosis in June 2011 and my last thoracentisis in Nov 2011, a total of 11.3 liters of fluid at 7 different times were removed from my left lobe. M 66 26 weeks
180 MG 1X W
5/17/2012
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 1  Stage 3-A lung cancer Long term side effects I'm 8 years out. I still have terrible insomnia. Neuropathy in my hands & feet. Chronic fatigue. Small end nerve damage from head to toe.Unable to concentrate multi task confusion.Memory & time loss. Muscle & joint pain. Acne. PTSD. Depression. Headaches. I was never told about these side effects. Nor was I told they could be life long. I had neurological testing done in 2014. I was told I have Dementia caused by chemotherapy. The chemo cocktail I was given included Taxol Carboplantin Benadryl & other meds. Also did 6 wks of radiation 5 days a wk while doing chemotherapy at the same time. F 42 15 weeks
50
4/18/2018
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 1  Return of tumour Nauseous, constipation, breathless, fatigue, extreme tingling in feet and hands. Could not have hot shower as it seemed too hot for my skin. Hair loss, lost some control over bladder but this has returned. A dreadful chemo . Skin rash covering entire torso, under arms etc the rash changed the colour of my skin. 73 14 weeks
10/12/2019
 5  breast cancer fatigue I am on weekly taxol for twelve weeks, just finished my fourth. So far my only side effects are some fatigue after the decadron steroid wears off, and a little stomach acid so I avoid spicy foods. No hair loss yet, although I'm expecting it. No neuropathy or joint pain as others have described. No other side effects. I was on AC for four cycles before and it was horrible. Compared to that, this is a walk in the park! F 48 12 weeks
6/19/2009
 5  LB Mastectomy (After AC chemo x 4) As the cycles progressed - extreme fatigue (could never have imagined it happen to me, It overwhelmed me) Metallic taste in mouth (drove me insane) Finger and Toe nails affected (mainly index fingers and large toe nails) Brain Chemo My hair fell out almost immediately with the AC chemo, but with Taxol, the last of it fell out and then my eyelashes and eyebrows all fell out and my body hair followed suit. If it works, go for it! as much as I did not like the side effects of it, you manage to get through it. The recovery from the side effects after the 12 cycles has been fairly rapid for me. So I am delighted. F 60 12 weeks
80mg 1X day
8/31/2014
 5  IDCS Breast Cancer Continued form previous post:week 5: mouth sores for a couple of days. Very achy from the granix-. I never dip below 4 again so did not take additional shots for the rest of the chemo. Hair continues to fall out, but still cant notice. Week 6: severe itching/tingling of feet, mostly at night. Drives me crazy. Double my L-Glutamine to 1500 mg/2x day and it goes away. I stay on that for the next 11 weeks. Hair coming out more. Week 7: Noticeable difference in energy level. Days 3-5 tired. Hair continues to fall out. Nausea in middle of night which wakes me up, but lasts only a few minutes. Week 8: tired, hair falling out. Week 9-12: Tired. Hair really falling out. Weird cold sensation in my veins when I get the chemo, but not sure if from taxol or the premeds. I almost passed out week 11 so they stopped it for 30 min and waited until I felt better. Week 13.Felt the worst I did the entire time. Tired, low energy, with some nausea in the night that woke me up, but again short la #2 of @ post with week by week descriptions for Taxol F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  IDCS Breast Cancer, post lumpectomy I really wanted the week by week, so here is what it was like for me. This is a blow by blow but overall let me say that on a scale of 1-10 (10 being awful), even on the worst days I would give it a 4. I never missed a day of work, though I did go to bed earlier and sometimes slept in. At week 14 I did a fast, 1 week turn around trip to Africa, and though tired, actually felt mostly OK. Week 1: No side effects Week 2: mouth sores for about 3 days, the first day it felt like a burned my mouth (like after you eat a hot piece of pizza) The third was somewhat sore, like having a bunch of cold sores. Then it just went away on its own Only came back for a couple of other days around week 5. Also low white blood cell count (3) from a starting point of 14. They give me neupogen the day before next session (Week 3). It works (WBC 27) but really makes me feel achy in my bones for a day. Insurance will not cover, so they switch me to granix. Went for a 3 day 35mile backpacking trip aft Diagnosed at 48. Triple positive so had weekly taxol for 12 weeks starting 5 weeks post surgery to remove lump. Also taking Herceptin which I started first. Side effects worse than Herceptin alsone, but overall quite manageable. I worked the entire time, continued to exercise (but was more tired). F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 5  Stage IIA Breast Cancer After 4 treatments of AC, Taxol although isn't a walk in the park is easier. Side effects include bone aches days 3 - 5 usually starting in the afternoon. Fatigue. Bowel problems. Mucous in stool and stomach pain. No nausea. Nose bleeds. New side effect - rash on hands. Lost my hair during AC and seem to be losing more with the Taxol. Currently on 8th cycle of a 12 week low dose Taxol. Looking forward to having some energy again. F 51 12 weeks
10/26/2009
 5  mastectomy/breast ca tingeling feet/hands-slight black fingernails-tired feeling-red rash on face from decadron(spell)taken night before.. took the once per week dose..did not loose eyebrows like everyone said I would..hair started growing back fast..still tingeling in feet/hands after last dose last week F 54 12 weeks
8/13/2007
 4  Stage IIa Breast Cancer Taxol has, so far, been so much easier than A/C that I feel as if I have been given a second chance. I am between week 5 and 6 of weekly infusions and so far the worst side effect has been insomnia the night of the infusion and fatigue on day 3. This has been so much easier to take compared to the first chemo. F 41 12 weeks
100 mg 1X W
6/10/2012
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 4  Breast Cancer No noticeable effects until after 4th treatment-now up to 7th. Rash and swelling on both ankles, muscles hurt during exercise, accumulative effect fatigue. After A/C -four 3 weekly sessions- Taxol is not so bad. However, I believe that the side effects are accumulative and depend on the dosage as well as the capability of the individual's body to deal with the drug. Just hoping I won't have problems with my nails!!! F 61 12 weeks
80mg 1X W
11/27/2011
 4  breast ca Interesting comment about the Claritan as I take that daily for seasonal allergies, and living in FL we have been in high pollen for weeks. I just finished Taxol last week and did well; common symtpoms were fairly mild and manageable. For the person needing advice re: nail fungus...try Tea Tree oil daily to the affected nails. This was recommended to me by a podiatrist for common nail fungus (another prevalent condition in this warm, humid climate). Tea Tree oil has a pleasant, medicinal smell and the oil base probably helps nail growth also. I find the oil I get at a reputable health food store to be a much better quality than the cheaper brands tried from big chain stores...hope it works for you. F 54 12 weeks
1X W
3/18/2011
 4  Breat Cancer Just some stomach problems but nothing that was that big a deal. All hair gone...including eye brows and lashes. F 50 12 weeks
200 1X W
10/10/2011
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