TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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 Type: Rx Drug

  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Stage 4 lung cancer Slight neuropathy and swelling of feet; slight tingling of fingertips; almost complete hair loss including all body hair. Side effects not suffered include nausea, intestinal problem, heart or kidney problems. I have had 20 injections (each lasting 2 hours) of Taxol in the last 26 weeks. I take 3 weeks in a row, skip a week, and then start another 3 weeks of injections. Currently I will be skipping 3 weeks (impending cataract surgery) and resuming weekly injections on June 13th. I have found that this skipping allows my body time to rebuild and not leave me completely drained and weak..The day of and the day after chemo are my coming down from the steroids days. Days 3 and 4 after chemo are generally my "don't do anything" and rest days. Days 5 and 6 are my "normal" and productive days. The latest CT scan shows that Taxol has reduced the cancer mass in my lung to one-third the size it was before Taxol. Prior to Taxol I was on Carboplatin every 3 weeks, however this chemo still allowed for the effusion to build up in my lung. Since starting on Taxol last November I have not had the need to have my lung drained of effusion (thoracentisis). As a comparison, between my diagnosis in June 2011 and my last thoracentisis in Nov 2011, a total of 11.3 liters of fluid at 7 different times were removed from my left lobe. M 66 26 weeks
180 MG 1X W
5/17/2012
Email
 3  Adv Metastatic BC stage 3C grade 3 I was treated in May 2006 first with A/C and after no affect 6 weekly doses of TAXOL. I had lost my hair from A/C treatments but after taxol I lost ALL my body hair. The neuropathy began my second treatment which was done while I had shingles. I know I am alive today because of this drug but I hate that for so long Doctors have not taken the long term effects of Chemo drugs especially taxol seriously. After almost 6 years I continue to walk like an 80 year old. My fatigue is severe, I have constant bone pain in both my lower legs, numbness, burning, aching, and shooting pains in my feet and hands. I am a single mom, a middle school teacher, and I haven't been able to work a full year since treatment. I have to take pain medications to work and it is depressing not to be the active strong person I was before treatment. I am thankful to be alive, yes, but please give us the information, care, and belief following treatment as well. I want to live happy not be in horrible psn and a burden to my kids. My older two live at home because of this and I hate that this has changed their lives as well!. F 50 6 weeks
max dose
4/10/2012
Email
 3  stage 2 breast cancer Put on after severe neuropathy caused by taxitere. Neuropathy continued to affect my feet but gone in hands. Lost 17 finger/toe nails. Extreme fatigue but continued to work from home office all but day of treatment due to time. Cracked corners of mouth, gooey mouth or cotton mouth. 2 weeks after last treatment extreme leg/joint pain and edema in legs. Still unable to do many things with my hands; buttoning, picking things up, holding onto things w/o dropping. Loss of balance, difficulty walking. Hoping these subside quickly. F 40 9 weeks
4/3/2012
Email
 3  Breast cancer Stage 3A I was just diagnosed last year MAY 2010. I can admit I am still alive but living in a body that feels like I am 90. I wake with such horrific pain I have to take my Morphine 30 mg instant release and 60 mg slow release. It takes about 1 hour to feel well enough to get out of bed, just to go to the couch, I can hardly stand for 5 minutes, I cannot climb stairs well, use handicapped parking areas to avoid walking so far, my legs feel like they are on fire. They pinch, burn, throb, ache, with pulsating pain and sometimes shooting pains. I can have a massage but as soon as I am finished they hurt equally to when it started. I have found a scalding hot bath helps until my morphine kicks in and takes the edge off enough to sleep. Since the taxol I have become an insomniac. I dont sleep well or at all with out the help of 2 sleeping aids. My arms up to my arm pits ache when things get really bad. Also I believe A/C first contributed for my hair loss but I am sure taxol didnt help because abou I too wish I would have known about these side effects. I noticed the extreme "I cant take it" kind of pain right after my 2nd dose of taxol, Where as A/C just made me feel like I had been hit by a bus and I was nautious the entire time. Those symptoms started the 2nd day after treatment and lasted until about day 10. Things were the very worse at about day 5 through 9. My quality of life is ruined. I used to work managing large hotels and was used to running around the building to manage things. I excercised regularly and lifted weights. I loved rollerblading and biking. My feet go numb after an hour of wearing shoes.I cannot keep up with my 3 year old. I am unable to work, not even able to depend on myself to wake up in time, since I dont sleep well, All I can say is without the morphine I am on, I would rather die than feel the extream intense pain I have when it isnt in my system. I have tried to go off of it many times but the pain is so horrific. I am looking for someone else like me, in my situation. I have tried ketamine infusions which they said will reset my nerve path but even that, which was helpful, did not work. HELP!!! F 31 2 months
2X M
12/13/2011
 4  Breast Cancer No noticeable effects until after 4th treatment-now up to 7th. Rash and swelling on both ankles, muscles hurt during exercise, accumulative effect fatigue. After A/C -four 3 weekly sessions- Taxol is not so bad. However, I believe that the side effects are accumulative and depend on the dosage as well as the capability of the individual's body to deal with the drug. Just hoping I won't have problems with my nails!!! F 61 12 weeks
80mg 1X W
11/27/2011
 4  BREAST CANCER nose bleeding, thick mucus and coughing, very cold hands and feet on the 3rd day of Taxol chemo, tingle in toes and fingers, finger nails is busy lifting Im very happy... Much better than the RED DEVIL... its a piece of cake after that...no pains in joints and my hair is growing.. F 59 9 weeks
50MG 1X W
11/8/2011
 4  Breat Cancer Just some stomach problems but nothing that was that big a deal. All hair gone...including eye brows and lashes. F 50 12 weeks
200 1X W
10/10/2011
Email
 3  stage IIIA breast cancer peripheral neuropathy after 8 treatments, severe joint and bone pain, felt like I was 90 years old (I'm 53). Much easier than AC but long term effects more pronounced. My doctor didn't have any answers for the long lasting joint pain but it DID disappear about 18 months after last dose. Previously had trouble getting out of a chair, felt stiff and sore, but after walking a few steps it would improve. I didn't think it would ever go away but happy to say there is light at the end of the tunnel! Still occurs once in awhile after a long day at work or exercise. No recurrences (yet) in 2 years so hopefully it was worth it. F 53 12 weeks
1X W
10/5/2011
 3  breast cancer stage 1 numbness in left toes after my 11th treatment. Also very tired by the third and fourth day and didn't bounce back till day 5 for the next treatment on day 8. Hair growing back on taxol AC was tough to take, taxol was easier in alot of ways until the numbness set in on left toes by the last treatment. Hopefully it will fade over time. Otherwise, besides crashing from the steroids 36 hours later it was a breeze. I am still tired from all the AC/Taxol treatments. total of 22 weeks. WHEW!!!!!!! Looking forward to radiation (10 minutes vs. 2 hours) F 50 12 weeks
124 1X W
8/11/2011
Email
 4  BC-Stage 1a Definite bone and muscle pain from the waist down. Tingling in fingers and feet. Usually subsides within 4 to 5 days. Loss of eyelashes and eyebrows as well as other body hair including facial and pubic(hair was already gone from AC). Bad taste in mouth. I have one more treatment to go and the Taxol is definitely harder than the AC but I am going to make it through! I have had my treatments on Thursday, shot of Nuelasta on Friday and taken the weekend to recover, returning to work on Monday after 7 treatments so far. F 47 8 weeks
2X M
7/26/2011
Email
 3  Fallopian Tube Cancer Severe neuopathy in hands and feet/toes. Loss of taste, dry mouth, inflammed veins, complete hair loss, and nausea. Due to the level of my neuropathy, my doctor took me off of the Taxol after the 3rd treatment. After a few weeks, some of the symptoms did subside and my hair did actually begin to grow back(not that this was my main concern), after 6 weeks. Everybody is different, but I will say that the recovery period after each treatment without the Taxol was reduced by about a week. F 47 2 months
1X O
5/29/2011
Email
 5  stage I grade 3 triple negative BC intermittent very mild neuropathy, some stumbling, but not too bad. a little fatigue, but not too bad. After the Epirubicin and Cytoxan, the Taxol is wonderful I think the pre-meds are the primary cause of my tiredness and malaise for a day or two after the treatment. my WBC and RBC counts are low, but staying constant I am ravenous due to the dexamethasone pre-med, but try to eat lots of proteins to keep my blood counts up. I take a couple tablespoons of blackstrap molasses every day, and I'm convinced that that is helping with the blood counts. F 49 6 weeks
12 weeks 1X W
5/15/2011
Email
 4  breast ca Interesting comment about the Claritan as I take that daily for seasonal allergies, and living in FL we have been in high pollen for weeks. I just finished Taxol last week and did well; common symtpoms were fairly mild and manageable. For the person needing advice re: nail fungus...try Tea Tree oil daily to the affected nails. This was recommended to me by a podiatrist for common nail fungus (another prevalent condition in this warm, humid climate). Tea Tree oil has a pleasant, medicinal smell and the oil base probably helps nail growth also. I find the oil I get at a reputable health food store to be a much better quality than the cheaper brands tried from big chain stores...hope it works for you. F 54 12 weeks
1X W
3/18/2011
 5  MD Anderson I am in my 9th week of Taxol treatments and have not experienced any major side effects. (oh, except for my hair thinning out) i take my treatments on Saturday mornings so I have the weekend to rest. I still work full time in upper management. Everyone responds differently to treatment. F 40 9 weeks
1X W
2/22/2011
 2  Stage 2 - Triple Neg -Breast Cancer Peripheral Neuropathy set in following the first Taxol treatment, hands first then feet. I lost all skin on my hands, numb at the tips, sharp electric shock feeling when I touch things. Side affects got worse following each treatment. Lost toe nails after second treatment and big toes hurt, finger nails are now purple and they say the finger nails will probably fall off too. The pain is intolerable at times, especially at night. After a few weeks it has gotten a little easier to walk, hands are arthritic feeling, ankles hurt - I just hurt all over and I feel 90 years old instead of my usual active and happy self. Not sure if it was worth it yet as I had chemo first, with surgery to follow. I cherish my quality of life over length and this is far more severe side affects than I was told to expect with only 4 treatments. They gave me pain meds the first few weeks, but now suggest the symptoms should be subsiding and I should use natural remedies and buck up and it will go away in Chemo is poison for some and medicine for others and doctors are not sure how anyone will react for sure. More research is needed to find a cure, but in the meantime more emphasis should be spent on treating the side effects and not just the cancer. Side affects are real and most often pushed off onto the aides and nurses to treat and unless you get a really qualified nurse, this can be emotionally and physically very difficult. F 51 7 days
2X M
2/20/2011
 4  Stage IIB Breast Cancer The main difference between Taxol and my A/C chemo treatments is the pain in my bones and my abdominal distress. Of course I have fatigue, complete hair loss, eyebrows and eyelash loss, weight loss of 40 lbs because everything tastes horrible, and sometimes I just get sick and tired of being sick and tired! I was told by one of my chemo nurses to take Claritin after chemo and IT WORKED really well! I have very strong pain medicine that doesn't even work, but the Claritin (just one pill) helps with the pain. I also take 3,0000 mg of L-Carnitine - 1,0000 mg 3X a day and have not experienced any tingling or numbness...yet anyway. I hope this helps someone feel better. I still have five more treatments to go. I am a middle school teacher and could not work at all with A/C chemo treatments - 4 rounds after a double masectomy and 38 lymph nodes removed. I went back to work 3 days a week on Taxol. I am tired and in a bit of pain, but I'm praying to be cured and cancer free after all this. I also have 33 radiation treatments to look forward to. I think you just have to try to stay positive and remember you are not alone in this fight. I wear a shirt that says, "Fight Like a Girl!" Would be happy to correspond with anyone who needs a friend to talk to. F 51 7 times
30 mg 1X W
2/10/2011
Email
 3  Grade 2 invasive ductal carcinoma Very severe pains in the legs started three days after the first dose was given. Lasted three days. No painkillers seemed to work and it was awful. Also got peripheral neuropathy (numbness) of all toes and fingertips, plus slight nosebleeds and gum soreness but all manageable. F 52 1 days
? 2X M
1/14/2011
 3  Stage 4 Met. Breast Cancer, Her2+ Been on some sort of Chemo, radiation or Cyberkife since 2004! Started out after surgery in2004 AC+T 4 rounds each. Stopped after round 3 of Taxol, feet, arms and legs one giant blister. Went on to many other types of chemo, Navelbine,Tykeb,Arimidex,Taxertere,Herceptin. Different combos sometimes. Presently on Toxol and Herceptin and I'm in remission for the forth time. Had kidney stones removed 2 months ago. Itching, lack of sleep, joint pain, not being able to eat, radiation burned my esophagus.Lost 50+ lbs.past 6 months.Working one day every 6 weeks having problems with my cell counts(RB&WB) getting shots of Neupogen. But Im still here and plan to go to my 40th reunion in July 2011. Seems to work well with Herceptin. Did nothing for me with AC. F 57
1X W
12/8/2010
 3  Stage 3 BC Much easier than AC. Initially, seemed like a walk in the park. After a few weekly treatments, joint pain, extreme fatigue, mild nausea, neuropathy, acne from steroids, memory impairment. My hair grew back while on Taxol! F 40 12 weeks
1X W
11/25/2010
 3  Stage 1 breast cancer Extreme fatigue - I was unable to work, read a book or, most days, even watch TV, muscle pain - especially in legs, complete hair loss midway through treatment, eventually toenails turned blue and split, premature menopause for 16 months after treatment, diarrhea, acid reflux, tinging feet and hands (neuropathy) that lasted a few weeks post treatment, but I id well with this side effect as it was only mild and went away very quickly when I was done with chemo. The last two weeks of treatment, I also got serious nausea. The fatigue was so bad by then that I could not drive a car for more than 10 minutes. It took about 3-6 months to begin to feel myself again. I also took this med with weekly herceptin, so it is not possible to precisely know which medication caused which symptom. But I am two and one half years past treatment, and I feel 95% recovered. Not fully regained my energy - yet. This medicine obviously affects people VERY differently, as working during treatment would have been a complete impossibility. F 45 12 weeks
unsure 1X W
11/7/2010

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