TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  breast cancer I experienced severe myalgias & neuralgias while on the drug, plus neuropathy in hands and feet. The neuropathy in my feet is still there to a lesser degree after 5 years. I have experienced a loss of cartilage at my great toe and foot joints - something the orthopedic MD says he does not frequently see in "someone like me." It is extremely painful and there is really not much you can do about it, except surgery to fuse the toe. I am concerned that the cartilage damage has been caused by the Taxol and that other joints will be affected. Has anyone else experienced this???? F 8 weeks
11/30/2005
 3  Breast cancer Stage 3A I was just diagnosed last year MAY 2010. I can admit I am still alive but living in a body that feels like I am 90. I wake with such horrific pain I have to take my Morphine 30 mg instant release and 60 mg slow release. It takes about 1 hour to feel well enough to get out of bed, just to go to the couch, I can hardly stand for 5 minutes, I cannot climb stairs well, use handicapped parking areas to avoid walking so far, my legs feel like they are on fire. They pinch, burn, throb, ache, with pulsating pain and sometimes shooting pains. I can have a massage but as soon as I am finished they hurt equally to when it started. I have found a scalding hot bath helps until my morphine kicks in and takes the edge off enough to sleep. Since the taxol I have become an insomniac. I dont sleep well or at all with out the help of 2 sleeping aids. My arms up to my arm pits ache when things get really bad. Also I believe A/C first contributed for my hair loss but I am sure taxol didnt help because abou I too wish I would have known about these side effects. I noticed the extreme "I cant take it" kind of pain right after my 2nd dose of taxol, Where as A/C just made me feel like I had been hit by a bus and I was nautious the entire time. Those symptoms started the 2nd day after treatment and lasted until about day 10. Things were the very worse at about day 5 through 9. My quality of life is ruined. I used to work managing large hotels and was used to running around the building to manage things. I excercised regularly and lifted weights. I loved rollerblading and biking. My feet go numb after an hour of wearing shoes.I cannot keep up with my 3 year old. I am unable to work, not even able to depend on myself to wake up in time, since I dont sleep well, All I can say is without the morphine I am on, I would rather die than feel the extream intense pain I have when it isnt in my system. I have tried to go off of it many times but the pain is so horrific. I am looking for someone else like me, in my situation. I have tried ketamine infusions which they said will reset my nerve path but even that, which was helpful, did not work. HELP!!! F 31 2 months
2X M
12/13/2011
 4  Triple Negative Breast Cancer Some fatigue on days 3-5 post treatment. Some joint pain in shoulders. My hair thinned out significantly, although I didn't lose it completely. I ended up shaving it off anyway since my insurance paid for a wig. I just had my 9th treatment (3 more to go) and I have been getting headaches now for the past couple of weeks. Today's was the worst yet. Hoping they subside soon. I haven't had any major issues with Taxol. My chemo experience thus far has been better than I anticipated. I begin FEC in 3 weeks and I'm hoping it goes as smoothly as the Taxol has gone. F 35 12 weeks
1X W
4/15/2010
 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 4  Stge 3 G3 Triple negative breast CA Joint pain in legs, arms & lower back, numb fingers and feet. I received this treatment after 8 weeks of AC which was a non-stop nausea ride & lost all my hair. I would take Taxol over that anyday. No motion sickness or nausea. I've worked full-time (office) while getting both treatments & I'm alive. Yay! F 37 8 weeks
1X W
9/29/2010
 4  breast cancer/neoadjuvant I'm tired on days 2,3 and a little on 4 after weekly treatment. I do work 40 hours a week and have a 1 1/2 year old. Other than fatigue I have a couple of days of body aches. Although I'm tired, I still need to take something to help me sleep through the night. I have 7 more weeks to go and my tumor has shrunk in half after 5 weeks. I take Advil for aches. No neuropathy so far. My hair started coming out and I cut it real short. I don't know yet if I'm going to lose it all on Taxol. I will on my next regimine. Oh well. F 37 5 weeks
3/6/2008
 5  Triple negative breast cancer Severe joint pain/stiffness in fingers knees and hips and shoulders.mild tingling to bott of feet. Crazy hot flashes. Occasional headaches. I received 12 weekly rounds of taxol.i had to stop carboplatin after 4 doses due to severe neutropenia F 39 3 months
6/16/2016
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 5  MD Anderson I am in my 9th week of Taxol treatments and have not experienced any major side effects. (oh, except for my hair thinning out) i take my treatments on Saturday mornings so I have the weekend to rest. I still work full time in upper management. Everyone responds differently to treatment. F 40 9 weeks
1X W
2/22/2011
 4  Breast cancer after Hodgkin's Disea This is my 2nd time with chemo, much worse this time, especially during & after Taxol, lots of pain in back, knees, feet, hands & shoulders, feels like severe arthritis, can barely walk worried I may need a wheel chair soon to get around, walking helps, but when I stop walking, I get stiff and pain returns Kind of regret taking Taxol because my quality of life has diminished, I no longer enjoy going out or shopping because I am in so much pain. I see 90yr olds who walk better than I do. My worse fear is that it is only going to get worse as I age, will try any medication to alleviate pain, Lyrica didn't help. F 40 6 days
12/22/2007
 4  Breast Cancer My only side effects has been bad breakouts on my face and head which has cleared tremendously after my MO prescribed a cream (for my face) and antibiotics for the breakout on my head (folliculitis). Other than that my energy level has been the same. No neuropathy or tiredness. F 40 7 weeks
80 MG
4/20/2016
Email
 3  stage 2 breast cancer Put on after severe neuropathy caused by taxitere. Neuropathy continued to affect my feet but gone in hands. Lost 17 finger/toe nails. Extreme fatigue but continued to work from home office all but day of treatment due to time. Cracked corners of mouth, gooey mouth or cotton mouth. 2 weeks after last treatment extreme leg/joint pain and edema in legs. Still unable to do many things with my hands; buttoning, picking things up, holding onto things w/o dropping. Loss of balance, difficulty walking. Hoping these subside quickly. F 40 9 weeks
4/3/2012
Email
 3  Stage 3 BC Much easier than AC. Initially, seemed like a walk in the park. After a few weekly treatments, joint pain, extreme fatigue, mild nausea, neuropathy, acne from steroids, memory impairment. My hair grew back while on Taxol! F 40 12 weeks
1X W
11/25/2010
 4  Stage IIa Breast Cancer Taxol has, so far, been so much easier than A/C that I feel as if I have been given a second chance. I am between week 5 and 6 of weekly infusions and so far the worst side effect has been insomnia the night of the infusion and fatigue on day 3. This has been so much easier to take compared to the first chemo. F 41 12 weeks
100 mg 1X W
6/10/2012
Email
 4  bc Numbness/tingling in toes and fingers; also experienced some pain in joints. Lost any and all remaining hair (eyebrows, eyelashes, nose, arms, etc.) But worth it to save my life. Had four rounds of A/C and four rounds of Taxol. Finished last taxol treatment two weeks ago; tingling hasn't gotten worse but it hasn't gotten better either. I walk everyday which helps immensely. Also take B6 supplement as suggested by my oncologist. Also noticed that a foot massage at night helps me sleep without interruption. F 42 2 months
8/3/2007
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 1  Stage 3-A lung cancer Long term side effects I'm 8 years out. I still have terrible insomnia. Neuropathy in my hands & feet. Chronic fatigue. Small end nerve damage from head to toe.Unable to concentrate multi task confusion.Memory & time loss. Muscle & joint pain. Acne. PTSD. Depression. Headaches. I was never told about these side effects. Nor was I told they could be life long. I had neurological testing done in 2014. I was told I have Dementia caused by chemotherapy. The chemo cocktail I was given included Taxol Carboplantin Benadryl & other meds. Also did 6 wks of radiation 5 days a wk while doing chemotherapy at the same time. F 42 15 weeks
50
4/18/2018
Email
 1  Breast Cancer Taxol was horrific. This was my second primary breast cancer so I couldn't use Adriamycin again. From the very first treatment I could barely walk. Began treatment in May 06 and finished in August. I thought my symptoms would get better when I finished, but it only got worse. I have always been active and now have to struggle to walk or even move on some days. I am 43 and I walk like my grandmother. Feet, hips, shoulders and hands hurt terribly. F 43 4 months
4/2/2007
 5  Metastatic breast cancer Fatigue was the only important one; one day mostly in bed for each weekly cycle. My hair fell out, but who cares? None of the nausea/vomiting I've experienced with other chemo drugs. No peripheral neuropathy. Only very mild and occasional joint pain. I had 16 weekly doses of Taxol over about 6 months; 3 weeks on 1 week off with a long break over Christmas due to going on holiday rather than medical considerations. Having weekly doses seems to reduce the side-effects without reducing the efficacy (there is scientific evidence for this, not just my opinion). It was palliative in intent, and it has worked ie my various tumours have shrunk in size. F 44 6 months
3/12/2007
 4  ovarian the main side effects I have had is being somewhat tired and weak feeling, food tastes and dehydration the first few days after treatment. I received 8 cycles in 2005 and now am near the end of 6 cycles. I have experienced no neuropathy during or after either of these cycles. And taxol has decreased my CA125 down to normal each time. My doctors are amazed at how well my body is handling treatments. Frankly, I am too. F 44 4 months
2/27/2007
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 3  stage 1 breast cancer I got taxol weekly, and this reduced some of the side effects but I have nothing to compare it to in order to say "yes weekly is better". I would start feeling sick the day after i got it, and this sick feeling would last about 5 days, and then I would recover day 6 and 7, and then it was time for the next dose. I got severe fatigue that felt like a horrible flu, very serious weakness, digestion problems, acid reflux, diarrhea, lost menstrual cycles after 4 weeks, some mild tinging in toes and hands. Some itching. At the end, serious muscle and joint stiffness - that felt weird and annoying. A lot of taste distortion and lack of appetite sometimes. The very last two weeks, I also got nauseous, but did not take medication for this because of side FX... though later tried ativan and this worked. I also had a few nails that became loose on toes and fingers; one toenail turned purple. Red counts down but not white count. Hair loss and some body hair loss (legs) of course an I am about 4 months passed Taxol. It took me 2 full weeks to feel ... well, i cannot say better, but I would say "not sick", but there were other side effects that lingered until now -- fatigue being the worst one. the mild neuropathy only lasted a few weeks after completion but it showed up again in tiny spurts later - dr said this is part of the healing, and now I am OK in the respect. I still have acid reflux but this could be due to the herceptin that i still take. I also still had joint stiffness though it is improving. But this does not stop me from working out, i just feel creaky and stiff. *I got acupuncture every week during treatment and still get it*, and this has been proven to improve immune system and neuropathy. This could be why i did well in this respect. All in all, taxol felt like a very strange and awful virus. It was very hard to deal, with but it was worth it to know that it reduces chance of recurrence. I cannot say I am 'satisfied' because I w F 44 12 weeks
12/11/2008
 1  Breast Cancer I finished chemo six months ago, and I have had lingering side-effects from Taxol that make me regret having taken it for primary bc. I have very bad pain in all my joints (especially shoulders, elbows, knees, back). I also have a great deal of muscle pain in my arms and legs. I am 44 years old and I walk like a ninety-year-old. It is very hard for me to get around. My immune system is shot too: I have on-going shingles, sore throats, and mouth sores. No one told me my quality of life would diminish so severely. Question your doctor about future quality of life issues before you begin Taxol. F 44 4 times
9/25/2005
  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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