SERZONE Reviews (NEFAZODONE HYDROCHLORIDE)Average Rating: 3.5 (164 Ratings)Filter ResultsCompare SERZONE with similar:
Type: Brand name discontinued; available as generic
|
Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SERZONE: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SERZONE | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | Anxiety, depression | My dose is currently about 125 mg at night. Blurred Vision: I'm 56 have had to use reading glasses since I was 46, but with this drug, my far sightedness, which used to be excellent, is blurry now. Mornings, I'm sort of foggy and confused. I feel clearer in a few hours. I've lost 10 pounds, but that's probably because I'm also tapering off from Paxil, which has to go very, very slowly, due to the withdrawal symptoms. | On the plus side, unexpectedly, my sex drive is coming back! It's been away since about 1990, when I started taking SSRI's. My mood is good and there is no rumination. Getting to sleep is easy but staying asleep for more 3-4 hours is not possible. Then I take about 1/8 of an Ambien, which works for me. Anti-depressants that have worked for me in the past are Prozac, Celexa and Lexapro; although I've tried many others. | F | 56 | 2 months | 5/29/2008 | 1 | Anxiety | Worst headache ever! | I never get Headaches. But after my first dose of Serzone I got the worst pounding migraine headache ever. I was literally on my bed in a ball crying. It's the worst drug I've ever taken! I stopped taking Serzone immediately. | M | 39 | 1 days | 4/5/2008 | 1 | depression | My first symptoms were plugged ears which later changed to tinnitus which lasted for 5 years after I discontinued the drug. I took this drug for 2 years and spent the 2nd year trying to get off of it. Serzone is difficult to stop taking as it causes muscle pain with withdrawal. Seven years later, I have no lasting side effects. | You should wean off this drug very slowly. | F | 49 | 2 years | 2/21/2008 | 1 | depression | This drug was removed from the market in Canada because it causes liver failure. I know someone who died from ingesting this drug. Acupuncture is an incredibly effective treatment for depression without the associated severe risks of antidepressants, and has the added benefit of improving one's overall appearance. And acupuncture works after the first treatment. | F | 29 | 3 months | 2/17/2008 | 1 | treatment-resistant depression | grogginess, blurred vision, delayed reaction time, general fatigue, worsening depression, self-harm urges | For two weeks (during which I had a particularly nasty illness), I took 50 mg each morning and evening. For the next month, I took 100 mg each morning and evening. At this point, I was experiencing few to no side effects, and no discernible intended effects. After about a month of this, (on January 12th) I was directed to increase the dose to 100 mg each morning and 200 mg each evening, and all hell broke loose. For the last two weeks, I was experiencing a lot of the side effects that I remember from trazodone (grogginess, blurred vision, delayed reaction time, general fatigue), along with an extreme worsening of my depression, including feelings of uselessness and urges to hurt myself. | F | 27 | 2 months | 1/22/2008 | 3 | Depression and Anxiety | I was on a dose of 600 milligrams for a while and became more depressed and anxious than ever. I switched doctors and the new doctor dropped me down to 450 milligrams. That worked fine for a long time and I didn't really have any side effects except for occasional anxiety and depression. I started cognitive therapy and over the course of two years tapered completely off the Serzone. I have felt fine in the two months that I have been off it. I have one month prescription handy just in case. I would consider taking it again if necessary. | F | 53 | 7 years | 12/5/2007 | 5 | bipolar, anxiety, depression | No side effects compared to the other antidepressants I have taken. | I have tried Zoloft, Paxil, Cymbalta I have also tried seraquol and abilify. And none of them worked. Or they gave me such bad side effects that I was hospitalized. I am currently on 1800 mg of Neurontin, 600 mg seazone, and 300 mg wellbutrin and I have never felt better. No fogginess, no sexual dysfunction, no panic. | F | 39 | 8 years | 11/28/2007 | 2 | depression, anxiety, dissociation | Weird visual "trails" when I was really tired, or when I didn't get enough sleep, or when I was particularly anxious. Mostly this was when I coupled the med with a benzo for anxiety, though it could sometimes cause the visual disturbances on its own. They were really scary until I figured them out. I stopped taking the medication because I worried about what it was doing to my liver. | Can cause serious liver problems. Isn't even approved in many countries. I had my liver functions tested often, and eventually decided to go off of this because of the liver dangers. My psychiatrist disagreed with me, but the risk wasn't worth it to me. | F | 30 | 1.5 years | 10/13/2007 | 4 | Bipolar Depression | Drowsiness, nausea | Helped greatly with anxiety which accompanied my BP II depression, allowed me to function at a better level for many years. It did not help the depression so much, but it did not cause sexual side effects like most other medicenes, so that was a huge plus. It became unavailable to me in April of 2005 so I quiut using it and have not been able to find a replacement. When I found a generic Nefazodone, it did not seem to work again and became severely drowsy to the point of making it not feasible to take the drug anymore. | M | 30 | 9 years | 10/10/2007 | 4 | severe depression | Took it only a couple of weeks because I became concerned about the possibility of liver problems. During that time, though, I slept well and felt less anxious. If I took a klonopin at betime also, though, the next day I would be ravenous and could not stop thinking of food. Dr. warned me that Nefadezone would enhance klonopin's effects and I should reduce it. Other anti- depressants have not worked for me, but I am not willing to rish liver failure and some of the other problems I have read about even if they are rare. | F | 54 | 14 days | 8/7/2007 | 1 | Depression and anxiety | Weight loss, insomnia, dizziness in head 30 mins after taking dosage each morning. | This was the least effective of the anti-depressants I have been on. I stuck with it for awhile because it did not affect my libido. However, I did not realise at first it was keeping me awake at night which in effect made it difficult to focus. during the day I also lost too much weight on it. Friends thought I looked gaunt and unwell. I also picked up every cold or flu that was going around while being on this. It is no longer available in Australia. I felt that it only marginally lifted my depression. AVOID ANJD LOOK FOR SOMETHING ELSE | M | 40 | 2 years | 7/6/2007 | 5 | depression | I took Serzone for several years and now take Nefazodone. I have had great results with it, libido back, weight loss, sleep well. I make sure to take it after eating as it caused nausea on an empty stomach. I currently take 200 mg. after breakfast and 200 mg. before bed with no food as I get no nausea then. I have experienced loose stools since taking these drugs and now have early morning diarrhea (starts at 6:00 a.m.) 2-3 times - quite severe. This has gotten worse over the past six months or so and causes me to feel rather "wiped-out" for a while in the morning. Are other people experiencing this after long-time use of Nefazodone? I previously took Paxil and experienced weight gain after a while and sexual disfunction all the time. | The grading of 5 does not reflect my intestinal problems. | F | 63 | 5 years | 6/14/2007 | 5 | major depressive and panic attacks | My side effects were sleepiness and nausea at night but the side effects were well worth it to me. | I too had tried everything on the market and nothing worked like serzone. for the first time in my life i stopped feeling suicidal and I stopped crying every day. My panic attacks went away until recently. I have to transition to another med becuase I have plateau at this med. I am now transitioning onto trazadone and so far its working well not as good as the nefazadone but better than alot of the other stuff I've tried. I was devastated to find out it wasn't covering me anymore, for the last twelve years, it has been a God send for me. Sorry others had a bad experience with it, it just goes to show how chemically different we all are. | F | 31 | 12 years | 4/14/2007 | 5 | Severe Anxiety & Depression | After unmanageable side effects on Paxil, Effexor, Zoloft and a 60 lb weight gain and body tremors from a trycyclic, Doxepin, the side effects for Serzone were non-existent by comparison. The weight gain literally dropped off when I switched to Serzone. | I have been on this drug since its' debut on the market (1995?)and all liver function tests return normal. It has allowed me to live a fairly normal, high functioning life. It is now available under the generic name, Nefazodone. I take 150mg per day which is below the originally suggested 300-600. I think now that 200mg is considered a high dose. I would like to get off the drug but am concerned about the return of symptoms and not being able to function and how much time it might take to get balanced again on a new anti-depressant. I am also afraid of staying on a drug that has been pulled from the shelves in other countries and is only available in USA as a generic. It has been the only drug that has worked and there is no other drug out there that is chemically structured in the same way. So, I feel stuck in between the proverbial rock and a hard place. Has anyone that had good success with Serzone found the same success with switching to any other anti-depressants (e.g.,Cy | F | 48 | 12 years | 4/11/2007 | 5 | Major Depressive Disorder | None! Great drug for me. Now mixed with Depakote with no problems. | Works like a dream for me. I'm up to 600 dose with no issues what-so-ever. No more crying spells or suicidal thoughts. No sexual side effects. For me a great drug. | M | 50 | 2 years | 4/11/2007 | 5 | | 4/3/2007 | 5 | Beacause I used to take it. | Nothing I can't handle. It's a nice feeling to be back on something that makes me happy and is very easy to control. | I was on Serzone about 6 yrs ago, then I discontinued because of the scare. Honestly I thought Serzone was off the market... I recently got back on it and I feel great. I was previously on Lamictal and Ambien, but those meds have nothing on Serzone. Serzone cured my depression, anxiety, bi-polar, sleep disorders, etc. I feel happy and sexy again! By the way, this is a very good drug for people that may have done acid or extacy back in the day. If you're anything like me, SSRI's are a BAD trip!!! Serzone is perfect! | M | 29 | 6 months | 3/21/2007 | 1 | depression | numbing of emotions initially, then panic attacks, sleep paraylsis, eventually became delusional, started having simple and complex partial temporal lobe seizures, then became psychotic as dosage was upped. Dr was also giving me Xanax for the panic, which may have contributed, as they should NOT be taken together. Dr didn't listen, just kept changing my diagnosis (from depression, to bipolar, to schizo, etc) raising dose and adding more meds (depakote and neurontin, then lamictal), very irresponsible of him, and shame on me for not trusting my instincts | Was horrible for me, the out of body experiences during seizures were bizarre, the psychotic episode was long lasting and ruined my life, lost my husband, my son, all my friends, horrible drug for me. Had never had any psychotic episodes, seizures or panic attacks prior to using this drug, and none since. will never use any ssri, snri's again, haven't been the same since-irritable, much less patient and just traumatized by what happened. | F | 34 | 9 months | 3/20/2007 | 1 | Major Depression w/Anxiety | Paranoia, irrational thoughts, extreme insomnia (72+ hours without sleep), auditory hallucinations. Thoughts of suicide (even though I had no thoughts of this prior to taking this med.) | This medication made me go right from the frying pan into the fire. I wanted to stop this medication on the 2nd day but was advised by doctor to give it more time to work. On the 10th day after not sleeping for 3 days straight, I was taken to hospital by my friends when I began to seriously talk about suicide. Hospital immediately stopped Serzone, switched me to Prozac and Trazodone which worked far better in my case. I fear this medication could have killed me if not for my friends foresight in taking me to hospital. I have also met 3 other people since then that had very similar encounters as mine while taking Serzone. Personally, I would NOT recommend this medication under ANY circumstances. Fortunately it is no longer prescribed in my country. | M | 25 | 10 days | 3/19/2007 | 2 | depression/anxiety | none | didnt help much, very tiny bit | M | 20 | 4 years | 3/9/2007 |