ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)Average Rating: 3.3 (1668 Ratings)Filter ResultsCompare ZOLOFT with similar:
Type: Rx Drug
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More on ZOLOFT: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR ZOLOFT | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | Depression | Weight gain , dry mouth, poor sleeping, very forgetful,tired, lethargic | F | 52 | 25 years 100mg 1X day | 8/13/2021 | 5 | PTSD & Fibromyalgia | Weight gain | Zoloft literally saved my life from what I called "daymares" from PTSD. The flashbacks were so horrible that they made me worry about my sanity. They immediately disappeared and I've been able to control them if they try to pop up. As a side benefit, it dropped my fibromyalgia pain down at least 70 percent. Huge, huge deal. When I try to stop Zoloft, the fibro pain comes roaring in like a freight train. I wish it would diminish my libido significantly ... at my age .... | F | 72 | 22 years .50 1X day | 5/26/2019 | 4 | bipolar II | Increase mania: raging, lack of patience and sensitivity, body clenching, and hyperactivity (which sometimes works in my favor). This drug also causes less or no sex drive (boo) and wieght loss (yeah). | This med. really works to alleviate depession. I'm on a mood stabilizer (lamictal) along with the zoloft to give me a little kick to alleviete my depression. However with it comes increased mania. So, while I may not be depressed, I'm rageful and insensitive a lot of the time! | F | 45 | 20 years | 2/8/2009 | 4 | Obsessive Compulsive Disorder | I started on 200mg/day. Effective for OCD also eliminated anxiety. Had brain zaps and Restless Leg syndrome that affected the whole body causing a constant need to flex and move muscles. Had Muscle pain also, diagnosed as Fibromyalgia, I suspect that the muscle pain was a zoloft side effect. Decreased to 25mg for the past 5 years. Less effective for OCD, some obsessive thoughts break through but can be tolerated. Anxiety is back but mild enough to ignore. Side effects much better. Restless leg syndrome only occurs at night, and not every night. I can sit quietly and knit for long periods of time. No brain Zaps, muscle pain much less. 25mg gives me a tolerable balance of treatment and side effects. | It's been impossible for me to stop this drug. I can decrease it slowly but when I get down to half of a 25mg pill I can't seem to get lower. I've tried shaving off tiny bits of the pill over 2 week intervals but my body seems hyper sensitive to the decreases. I get a recurrence of OCD and anxiety, with the addition of anger, depression paranoia and irrational thinking that make me impossible to live with. The symptoms are worse than they ever were before I ever took Zoloft. Once I decided to simply stop it at the 12mg point and tough it out. I ended up in the hospital-- a psychotic episode. Worse than anything I ever had before Zoloft. | F | 60 | 18 years 25 mg 1X day | 6/18/2010 | 3 | Depression/anxiety | Restless legs Flatulence Decreased sex drive | Hard to tell what being on Zoloft prevented - would still sometimes get very down while on it. Felt more 'myself' after weaning off. One interesting point: 'night terrors', which I've had since childhood, are kept away when on Zoloft, but return when off it. | M | 53 | 17 years 100mg 1X day | 11/15/2011 | 3 | Severe Major Depression | Initially felt like I was on speed. Went manic, then crashed, and kept cycling. Had some sweats for a day. Makes me mildly flat. | I used to take it for depression but the depression was cured by antibiotics meant for a sinus infection. Zoloft did nothing for depression as long as I ate certain foods. I now take it for OCD and panic attacks. It is so-so for either of them. | F | 57 | 17 years 200 1X day | 1/15/2022 | 5 | Anxiety & OCD | First 4-6 weeks: Mild jaw clenching, harder to fall asleep. Dissipated after 4-6 weeks with no side effects. | This has been a life saver for me. In fact, it always works so well for me that I go off of it after 6-9 months because I feel so normal. I tend to get anxiety and OCD if going through a big stressor in life or in the winter time due to seasonal affective disorder. | F | 42 | 16 years 50mg 1X day | 5/22/2017 | 5 | depression & debilitating anxiety | Short term (1st 3 mos) gastrointestinal issues, weight gain with dose increases & "Discontinuation Syndrome" with fast decreases. Benzo tranquilizers seem to change the effective dose. I've taken 100 to 400mg. I think the high dose tolerance is due to the tranq. Reducing the tranq feels like increasing the Zoloft. Increasing the tranq feels like decreasing the Zoloft. | The drug changed my life for the better. It was literally a cure for debilitating anxiety, obsessive worry and social phobia. BUT dose changes have to be managed CAREFULLY! The discontinuation syndrome lasted almost a year before I was forced to go back on & reduce properly. I've learned how to manage my dose without any ill effect using adjustments of 12.5mg (break a 25 tablet) every 2 weeks. The drug is fantastic, but improper fluctuations in dose can cause serious! mood issues. Do your homework or call your dr. before changing your dosage. | F | 42 | 16 years | 4/14/2008 | 4 | Depression | Nausea if I dont take it with food, dry mouth, tiredness and bad dreams | I have tried many antidepressents and the only one that seems to work is zoloft. I have tried to go off antidepressants 3-4 times and always came back to zoloft. | F | 35 | 16 years | 7/1/2009 | 4 | OCD, Anxiety & Major Depression | I had no negative side-effects and loved Seratraline. It has helped me a lot more than earlier meds. However, I have tried to taper and quit several times and CAN'T. I become dizzy, nauseus and can't function; feel as though I'm poisoned. One tiny dose makes all that badness go away in less than 30 minutes! So, yeah, I know I'm an addict... TODAY I'd like to know if my recent muscular twitches are related to this medicine. | My belief is that once a person is on a med like this, his/her chemistry is changed, and, s/he can't "revert to the earlier version" of his/herself, so to speak. One is forever changed and cannot function as expected without the drug. | F | 51 | 16 years 100mg 1X day | 5/23/2012 | 3 | Depression | At first I went into mild mania. It was enjoyable, but I would crash into depression after several days. Doc added Seroquel as a mood stabilizer and the cycling stopped. I felt very hyper for four months as it was very stimulating | I had horrible depression because I was eating foods that would give me depression. As long as I avoided the foods I was okay, One day I had a severe sinus infection. Two courses of antibiotics must have killed enough bad gut bacteria. After the antibiotics I was able to eat whatever I wanted. The horrible depression left. I still take it for OCD, but Zoloft seems to be marginally effective for OCD. . | F | 56 | 16 years 150 1X day | 4/6/2021 | 5 | Depression/Anxiety | Initially I had insomnia. For 3-5 days or so but it was so worth it. | Since my ovarian failure I can't function without it. Within 2 weeks I found relief. It makes me feel like a normal person instead of being constantly tortured by my emotions. Since I am not constantly overwhelmed by pointless unexplained anxiety and depression I am able to think things through and just live. :) | F | 43 | 15 years 100 1X day | 12/11/2015 | 5 | Depression | fatigue | Did wonders for sexlife. poo poo gets stiff again would recommend to anyone that is depressed. Thank you too much. | M | 55 | 15 years 100mg 1X day | 9/5/2012 | 5 | Depression | None whatsoever, except more and more confidence that my chronic depression will never return. | I seem to have been born depressed. Unhappy, often suicidal throughout childhood and adolescence. Anti-depressants became available when I was in my twenties, and I was on and off them for years. The older types worked up to a point, but there was always an underlying feeling that depression would emerge, and sometimes it did. But since Zoloft, I've been able to live without that fear. It's totally changed my life. A wonderful drug. | F | 68 | 15 years 150 1X day | 10/13/2010 | 5 | depression | none | F | 38 | 15 years | 10/11/2007 | 4 | Depression/Anxiety | WEIGHT GAIN!!!!! HOLY COW!!! allot of weight gain. The other nasty side effect is if you forget to take it. You will end up with a light headed feeling and what I call "trailers' meaning that it takes your eyes a second to catch up with your focus. | M | 36 | 15 years | 9/26/2005 | 4 | Anxiety, Panic Attacks, Bi-Polar II | Not many, slightly reduced libido. | It really helped me get through some bad times in my life. I've been taking it every single day (in the AM), for over 15 yrs. No major issues to report. It seems to work well, especially when I first started taking it (takes ~ a few weeks to take effect). | M | 40 | 15 years 100mg 1X day | 6/6/2010 | 4 | depression related to health issues | difficulty reacing orgasm, weight gain | i've been taking zoloft for over 15 years and yes it works although the generic does not seem to work as well. as long as i do not exceed 100 mg, the above side effects are minimal. i've tried many other antidepressants over the years but had too many side effects and always came back to zoloft. | F | 55 | 15 years | 4/12/2008 | 5 | fibromylia | some dizziness, | creates unreasonable sense of ephoria at times when you normally shouldn't be that happy | F | 59 | 14 years | 7/14/2008 | 5 | Bipolar w/ Severe Depression | I've taken it so long-- 14 yrs--- that today I cannot name any undesirable side-effects. In the very first years, there was difficulty in achieving orgasm, but no ED at all. I remember the first four days on the drug were weird: I felt jittery and a little elated, rather like the opening to a hallucinogenic drug. But that subsided very soon. As everyone knows, you have to give the drug about a month before you decide you might cycle off it; people who decide after a week that "it's not for them" are really not using the drug correctly. I will say that withdrawal from Zoloft (or any SSRI) is a very unpleasant experience: severe mental confusion, and objects in your peripheral vision seem to dance about, wheel and lurch unexpectedly (not unlike the "tracers" of LSD). You seem to "miss" seconds of time. Crying bouts resume at the slightest provocation (Ask my family about the time I started crying over the breakfast tabl | I tell people that Zoloft gives me a Floor. A floor under my feet beneath which I shall not sink. This means that I'll still have good days and bad, but I know i have the security of an emotional "floor" beneath my feet. Before this medicine, I could sink...and sink... and sink into depression, seemingly without end. The biggest gift of Zoloft, I'd say, is that it allows me to *think*; those of us severely depressed know that, even worse than the dysthymia, is the inability to read printed matter... you'll read and re-read the same paragraph over and over again! Now I can think and read, and that's everything. They say the effects of Zoloft are smooth and constant, based on blood levels, but damned if I don't find myself feeling a little more cheerful/alert every day, an hour after popping my pills. | M | 50 | 14 years 200mg 1X day | 1/6/2014 |
ZOLOFT (SERTRALINE HYDROCHLORIDE): Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)