Drug Ratings for CLOZARILAverage Rating: 2.8 (52 Ratings)
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Results are sorted by Date Rating Was Added Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 |
Charts & graphs: Reviews Summary for CLOZARIL | Top 10 Adverse Effects (reported to FDA)
| RATING | REASON | SIDE EFFECTS FOR CLOZARIL | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 1 | Hearing voices | It was horrible, it droves me crazy. In and out of institute 30 times. I got tardive dyskinesia. I was misdiagnoses badly. Psychiatrist love gives medications to people with out observation correctly. I had drooling, sleeping too much, diabetes, swelling ankle, couldn't walk, causes heart problem, high blood pressure, very obesity, zombie, paranoia, anxiety, high white cell count and in so much pains. I end up 38 pills a day. I got off all medications and I am back to normal except I got Tardive Dyskinesia. I am fight with that disease which had no cure. I am not on any medications now. I am suffering daily. | I end up 38 pills a day. It had way too many side effect. I wouldn't recommend to offer that kinds of medications ever again to anyone especially to women. | F | 49 | 14 years 450 1X D | 3/31/2017 | 2 | Schizoaffective Disorder | Genitals shrinking, spaced out, hard to think, drooling and sweating when sleeping, apathy, craving drugs to feel good, unsociable, weight gain, vivid dreams | I hate this med, but im forced to take against my will. I have monthly blood tests and physical reviews by the doctor. | M | 22 | 6 months 350mg n | 3/27/2017 | 3 | Drug induced psychosis | Bed wetting 3x. Drowsiness. Weight gain - up to 110kg now 64kg. Anxiety. Depression. Embarrassment. | I was a drug addict from a very young teenager and constantly in trouble. I completed year 9 barely and attempted suicide at 15 with a dose of paracetamol at just about 63000mg. I was very infatuated with drugs, alcohol and my family life was unstable. I was molested as a child by my father 1 time I remember and again by him at 14. I was also raped in a caravan park at that age by a 37 year old man while looking for drugs and alcohol. This shaped me for the next few years into somebody I wouldn't recognise or want to today. I was introduced onto cloz* at 19 and I was and still am compliant. I have done a short tertiary course at university for 8 months, am part time employed as a support worker with a traineeship and hope to do a bachelor of nursing with hopes to work in an emergency department. However I am not getting support because of my achievements and how normal** I appear to be. I have moved forward with my life and grown into a mature responsible adult but I am suffering from anxiety attacks and moderate depression because I guess my past bothers me. I am embarrassed by it. I would like to try another medication. I do not want to be a mental health outpatient for the rest of my life because I haven't had my life yet. I am very driven and I am not where I want to be yet however I am slowly working towards being something I am proud of. I am getting frustrated because I pick up my prescription after a 3 minute chat to the lovely employees at mental health but I am not | F | 24 | 4 years 100MG | 3/12/2017 | 5 | Schizophrenia | Very tired after about an hour after I take it. I get real hungry after about 20 minutes. Problems with dizziness. I need more sleep than before. But it has been the best drug I have had. | Scared of what will happen if the blood work says I can't take it anymore, because this has been the only drug that has worked for my. I have been told I am a difficult case. And with this drug I haven't been hospitalized a little over two years. | F | 45 | 4 years 400mg | 1/27/2017 | 5 | Schizophrenia | Very tired after about an hour after I take it. I get real hungry after about 20 minutes. Problems with dizziness. I need more sleep than before. But it has been the best drug I have had. | Scared of what will happen if the blood work says I can't take it anymore, because this has been the only drug that has worked for my. I have been told I am a difficult case. And with this drug I haven't been hospitalized a little over two years. | F | 45 | 4 years 400mg | 1/27/2017 | 4 | Schizoaffective Disorder | Extreme drowsiness 1 hour after taking 300mg at bedtime. Very hard to get out of bed with only 6-8 hours of sleep due to the clozapine still in my system. If I have up to 10-12 hours, I wake up okay and feel normal. | Do not take huge dosage during the day. You may become very drowsy or even faint. Overall, I noticed a positive change in my behavior, thinking, and outlook on life. I feel stable. | M | 27 | 3 years 300 MG 1X D | 1/5/2017 | 3 | Cause I am afraid of suicide | It is hard to go stool but only saver to refrain from committing suiside. Good sleep with 0.5 mg rivotril. | M | 66 | 1 days 100. Mg | 10/18/2016 | 3 | phycosis | Tired weight gain memory problems | Don't like it | M | 29 | 1 months 300 mg | 8/31/2016 | 1 | schizophrenia | People say this is the best antipsychotic. I've been on it 3 times at different doses and it did nothing for me. The drooling at night was horrible. I definitely have treatment reaistant schizophrenia which clozaril is used for but nope was the same as the other drugs that didn't work. Disappointed... | M | 30 | 3 times 900 | 5/7/2016 | 4 | Bipolar 1 | Drooling droziness hard to wake up in morning. | It's the only medication that stopped the psychosis and helped the voices. Not totally but helped a lot. I'm now able to work and go to school. I'm able to concentrate its was a mirical drug for me. | M | 21 | 2 years 375 | 2/6/2016 | 5 | schizoaffective disorder | Puts me to sleep at night. Drooling while sleeping. Very hungry at night. | Only medicine that helps me fall asleep. | M | 35 | 6 years 200 MG | 1/25/2016 | 1 | Borderline Personality Disorder | Sedation, Weight Gain, Apathy, Paranoia | I took this medicine for 6 years. During this time, I felt absolutely dead to the world, and miserable. I gained 30 pounds and got scar tissue from the blood draws. I was forced to stay on this medication for far too long, and I cannot think of one positive thing to say about it. I have been off of it for about a year now, and I feel infinitely better. The withdrawal is absolutely terrible (severe headache, -extreme- insomnia, nausea, ect.) but it is definitely worth going through to stop taking the medicine! | F | 13 | 6 years 300MG 2X D | 1/14/2016 | 5 | Schizophrenia psychosis | Will knock you out for a while and weight gain | Only antipsychotic that helped me it works | M | 35 | 2 years 100 | 11/27/2015 | 5 | Suicidal | Sleepyness | This was the last resort for me, my doctor tried recently to take me off it, but I went through withdrawl, my body hurt and my mind was all over the place so we had to put me back on it .when I amoved on the drug I function better and am in more control of my own actions. | F | 30 | 12 years 1X D | 11/22/2015 | 2 | schizophrenia | sedation,panic attacks,drooling | F | 33 | 4 months 250mg 2X D | 8/30/2015 | 4 | schizoaffective/bipolar disorder | The worse one is tiredness;drooling;bed wetting. | It takes about 3/4 hours to "come too" in the morning. | M | 66 | 250mg 1X D | 8/24/2015 | 4 | Paranoid Schizophrenia | Drooling, a need to eat approximately an hour after taking drug in order to sleep, weight gain, sleep for 10-14 hours a night. | It hasn't gotten rid of the voices entirely but it has allowed me to have relationships with people and trust others to an extent. It has improved my life a great deal. I used to be unable to go out due to extreme paranoia about others. The drug has certainly helped in that regard. | M | 33 | 10 days 200MG | 7/22/2015 | 3 | Psychosis NOS | Drooling, bedwetting (got dose lowered and it stopped) Extreme drowsiness. | Paliperidone had no effect so they put me on it. Definitely helped with the psychosis but i hate the sleepiness so much. I mean sleeping 10-16 hours of the day. If i force myself up early im foggy and fall asleep by 630pm. I think im particularly sensitive to this because im on a really low dose so it may be better for others. I hope i can actually come off it in a year or two. | F | 22 | 1 years 1X D | 5/31/2015 | 5 | To control schizophrenia | Drooling. Seizures. The night you take it feel crappy and for awhile in the morning | Less suicidal. Helps to get along with others | M | 22 | 1 years 550 mg | 5/14/2015 | 1 | paranoia | drooling, knocked me the F out | Doctors swear this is the best antipsychotic. It's a big ball of crap. My paranoia and hallucinations were worse. And the drooling was like I waked up with my bed sheets in urine. | M | 25 | 2 years 600mg | 3/15/2015 | 2 | Schizophrenia | Clumsiness, lack of energy, tired and sleep too long. Seriouse memory loss, increased appetite, especially about an hour after taking it. After taking dose I can't leave home because I'm so extremely doped up. Siriosis, druling. (especially during night) | Before taking this medication, I would have considered myself to be your average Joe. Not only do I have a mental illness but I also feel mentally challenged. I'll just say that, taking this drug is NOT helping me find any kind of job because of its side affects and it's literally making me ill. | F | 41 | 1 years 1X D | 2/26/2015 | 1 | psychosis due to family tragedy | I turned into an ignorant drooling zombie but did everything in my power to defend the drug no matter what anyone said to me. | Don't take this drug. It destroyed my relationship with my partner. It was only after finally getting off this that I woke up and realized what I had been like. | F | 39 | 3 years 20 | 12/22/2014 | 1 | Phsychzophrenia | Major weight gain | Don't go on it especially if you don't want major weight problems something else like abilify which is also a second generation a typical medicine can be suggested instead and will work just as well | F | 30 | 2 years 275 1X D | 10/8/2014 | 1 | Paranoid Schizophrenia | M | 47 | 250 MG 1X D | 9/25/2014 History | 2 | Schizophrenia | Intense sleepiness till mid-day, after a few years this side-effect went. Drooling on my pillow at night. became obese on this drug. My muscles are ineffective on clozapine. Expect my gait to be different to others. have become pre-diabetic because of clozapine. | I don't want to be on this drug but have difficulty getting off this. Would like to say to anyone who is obese or fat on any drug, particularly this one, to ask their doctor to take a diabetes test. | M | 37 | 13 years 125mgs 1X D | 6/17/2014 | 1 | Schizophrenia.....& Psychosis..... | It is killing me slowly! I don't even know who I am anymore! I'm so unhappy but a fake smile always fools my doctors and other family members...I've lost all my friends! I shut myself out from the rest of the world. I will end my life soon... death is better than suffering like this for the rest of my life I just hate what this meds have done too me! Even thou I'm now only on 250mg reduced from the high amounts I was taking when I 1st started it. Much love to others whom suffer or feel like the way I do. Keep strong God knows what we are going threw never let others bring you down in life even if its family members...that's happened in my case... | M | 24 | 2 years 250mg | 5/26/2014 | 1 | They HATE you! | DEATH. NEVER voluntarily start taking this drug. Seroquel is better one. Lots of side-effects. | M | 34 | 1 days | 3/18/2014 | 5 | Bipolar 1 | Drooling (worse in first few years), weight gain, craving for sweets especially after a dose at night, sedation that lasts way into the next day, too much time on the couch watching bad TV. | Great drug for treating my terrible depression (suicidal thoughts) and for somewhat stabilising my rapid cycling. Hasn't fixed everything but I wouldn't like to think where I would be without it. At a time when I had run out of options it was a wonder drug for me. | F | 40 | 6 years 250mg 1X D | 9/19/2013 | 3 | Schizoaffective Disorder - Bipolar | Nighttime drooling, carb cravings, sedation | I had to switch to Clozaril after developing Tardive Dyskinesia on another anti-psychotic. I find my mood to be much better on it, and I have no hallucinations. I take the bulk of it at night, and I am really tired after an hour for about 3 hours, and then I am fine. Sometimes I fight going to bed, and have experienced hallucinations a few times when I did. | F | 54 | 9 months 150mg 2X D | 8/31/2013 | 1 | psychoses | Doctors are in ' love ' with clozaril at the moment coz it has been known since the 1950's. So ofcourse it is the most "studied" antipsychotic. I know someone on clozaril who drools during the day time and docs couldnt care less. But hey, what can they do about it? You have to be admitted in a psych ward to start on this. If you dont like clozaril youre in shit coz docs rarely take someone off it. Meant to be a miracle drug. Keep in mind EVERYONE IS DIFFERENT. Pretty arrogant claiming this will wipe out psychoses. Was a sugar pill for me. | M | 31 | 9 months 400 | 5/21/2013 | 4 | Bipolar disorder/insomnia | drooling, extreme tiredness that lasts well into the day | I am always leery about a drug that requires weekly, then monthly blood tests, but I will say that it is the only thing that has been able to put me to sleep for more than 2 hours. I have tried at least 30 different meds and none of them worked as well as clozapine. I've been taking it for almost 2 years now. | F | 36 | 100 MG 1X D | 5/3/2013 | 1 | Bipolar 1 - Schizoaffective | Drooling, sleeping for 24+ hours straight. | My daughter taxes Clorzaril and we were very hopeful but no difference in her life than any other drug she tried. Zyprexa, lithium, lamictal, haldol, seroquel etc. She is busy focusing on the voices in her head and doesn't talk much but this has been the ONLY drug she has asked and demanded to stop taking. She hates it but can't tell me why. It does make her sleep alot however and crave sweets. Doc cut her back to 400 mg and added 80 mg of Latuda and also kept her on seroquel in combination. | F | 24 | 5 months 650 1X D | 4/28/2013 | 1 | Schizophrenia | I took this drug because i had no choice. I was in a high secure hospital and quickly realised i had to jump through ihoops if i wanted to get out of there. I had to tell them what they wanted to hear and take the meds. All i wanted was to be my spiritual self. Theres no such thing as mental illness its a state of mind, albeit one that can be difficult, i did not want my soul destroyed by digital machines and chemicals and bullshit psychology. I hope we make spiritual progress for the sake of our future generations. They should not have to be tortured for having a spirit. This drug clozaril will destroy a part of you. It will damage your physical self just as much as your spiritual. Its like being connected to a machine. You feel good at first, silence and peace. But once you come off it, you realise how they are stopping you from being your true self. I realise i was a zombie for 5 years. These people do not want you to think for yourself. What is more dangerous. Being dead inside. I | Dont take it. Its the exact chemical opposite of ecstasy. After i have been off this drug for a while i start to get my natural thoughts back. But I cant sleep without it | M | 30 | 6 years 400 1X D | 4/6/2013 | 5 | Schizophrenia/Psychosis | Some drooling | Finally, after testing various other medications such as, Seroquel, Zyprexa, Abilify, and and Risperdal. All of these medications didn't help me stop hallucinating(audial). Clozaril, after about a week I was fine and living a normal life again. It's a hassle having to do all the bloodworks, but for me this has been a miracle drug. So it made the bloodworks worth it. After 1 year it is only required once a month(the blood tests). I am free of hallucinations and more focused then any of the other meds I was taking. I give this medication a 5. | M | 29 | 1 years 225 MG 2X D | 3/19/2013 | 1 | Paranoia | Clozaril was taken off the market in the 1960's as a result of deaths from Agranulocytosis. Now patients are tested for this. Plus have to have an ECG at least every 6 months. | M | 19 | 10 months 300 | 12/20/2012 | 1 | Schizophrenia | Drooling, drooling This is more sedating than seroquel. Clozaril is the most sedating antipsychotic. Clozaril has the more weight gain than zyprexa. | Like the comments before: UR bed when u wake up in the morning will be full of saliva. Yuck! The only way to stop salivating is to tell ur doc to take u off it. I can't get off this stuff keep relapsing and guess what? Doctors put me straight back on it again. My life is a misery and zyprexa actually worked better for me. | M | 2 years 600 1X D | 11/8/2012 | 2 | Schizophrenia | Drooling, knocked out straight after taking it | This is meant to be the 'Gold standard' the 'Best' antipsychotic. Did NOT do much for me. PLZ remember everyone responds differently to medication. The thing doctors rarely mention is that Clozaril is one of the hardest drugs to discontinue if you don't like the side effects. It can cause 'rebound psychoses' at its worst. Basically your psychoses can sky rocket off the universe by trying to get off this medication even if your doctor takes you off it slowly. Once on Clozapine you might be on it for the rest of your life coz of what is mentioned above. This can be a miracle drug for some people but for me my paranoia and hallucinations were NOT stopped and were actually worse. I hated the drooling which as far as I know can NOT be stopped by anything. Missing more than 2 doses in a row can make you have a relapse which happened to me. On the up side. This is the only antipsychotic that does NOT cause TD(tardive dyskinesia). If your doing fine on something else don't bother changing hoping for a cure coz at the moment there is NONE. | M | 11 months 500 1X D | 11/6/2012 | 5 | Schizophrenia | Extreme sedation, lethargy in the morning, excessive salivating, desire to eat sweets that is impossible to resist, heart races, panic attacks | Yes, there are a lot of terrible side effects. Yes, the blood draws are an inconvenience. But clozapine has controlled my schizophrenia better than any med I've been on before (been on lots of antipsychotics) | F | 19 | 1.5 years 200 mg 1X D | 4/11/2012 | 1 | Light schizophrenia | My son took it for 6 years and his worse of now-totally a vegatable.dont take this drug,its DANGEROUS! | M | 19 | 1 days 400mg | 4/3/2012 | 1 | sluggish schizophrenia | THIS IS DEADLY KILLER DRUG. THIS IS SIMPLY USED TO KILL IN MENTAL HEALTH INSTITUTIONS. IT JUST KILLS YOU. PERIOD. Outside (prison) hospitals this drug is almost never used because it is simply a KILLER drug. It is 100% unethical to use this drug. YOU DIE. | M | 30 | 1 days 1X D | 10/10/2011 | 5 | Schizoaffective/Schizophrenia | Drooling at night and Drowsiness and increased appetite | Clozaril has made me normal. I have no more symptoms of schizophrenia. I am very happy that I was put on this medication and I plan to stay on it. It is worth the trouble of the weekly blood draws. | F | 23 | 6 weeks 200 mg 1X D | 3/23/2011 | 1 | depression/bipolar II | Extremely sedating--I slept 12-14 hours out of every 24. Increased appetite. I lost my personality and became like a zombie. | I did not realize what clozaril was doing to me until I stopped taking it and the sedation wore off. Then I could see that the two years I spent on clozaril were two years that I spent as a zombie laying on the couch. I wish I had not taken this drug. | F | 41 | 2 years 200mg 1X D | 6/10/2010 | 1 | self-injury, bpd | drooling, EXTREME weight gain (in institution and not eating much too), drowsiness, not remembering events, bed-wetting, 100% zoned out, taken off because my white blood cell count dropped | this is the most EVIL med I have ever taken. My doc wanted to put me back on it saying that, "my white blood cell count didn't drop too far" last time I was on it. Doctors are currently in love with this med, it works for some, but event they have quite bad side effects from what I know. | F | 25 | 4 months | 1/11/2010 | 5 | Schizophrenia | Drooling, Sedation, Seizures | I have to take a seizure medication with Clozaril because my seizure threshold is low. Actually, if I take any antipsychotic I have to take an anticonvulsant, so it's not just Clozaril, it's just that I have to take a higher dose on Clozaril. Ah, for the drooling, you can take (sublingually) the eye drops that they give you at the eye doctor to dilate your pupils. It stops the drooling. I take a couple drops under each side of my tongue before bed and I don't drool at night...nice. My doctor taught me that one. When I went to fill my prescription for the eye drops, I had to explain it to the pharmacist...lol. I don't get too much sedation, I mostly sleep it off, as I take the med at night. I've tried all the meds and this is the best one. It even helps the negative symptoms, which are mostly what remained for me with the other meds. I had a lot of problem with "connecting" to people, which affected my ability to form relationships with people and my interactions with people. Clozaril helps a lot with that so I can relate to other people and "connect." It is hard to explain, but it definitely helps me feel human. For me this has been a great medication. | F | 37 | 6 years | 11/8/2009 | 1 | bipolar | gross medicine | doctors say this medicine is the best, thats a big lie and rumor. This antipsychotic did nothing for me. Most patients grow out of there bipolar or schizophrenia by the time they turn 30 years old anyway. | M | 29 | 2 years | 10/9/2009 | 1 | SCHIZOPHRENIA | This drug is the worst just terrible. | Impossible to take side effects are deadly. | M | 29 | 3 months | 7/30/2009 | 5 | schyzophrenia | drooling 1st 2years, constipation,eating sweets in the night,makes sleepy, hard to function in the morning | excellent,wonderful, saved my mind | F | 32 | 10 years | 12/28/2008 | 5 | schizophrenia | The First year or so, alot of drooling, very tired. Major weigt gain. Id rather be ovedrweight than psychotic. | great efffects though from the voices. Been on it since 1992. Been on them all. This is the best. No more voices. | M | 44 | 16 years | 12/17/2008 | 5 | bipolar depression | super-intense weight gain via surge in appetite 45 mins-1hr later,bed wetting,extremely sedating,and drooling | The ONLY reason I gave this med a 5 is because it is the only med in the universe that will put me to sleep.NOTHING else works.I do hate this drug for the side effects,especially the bedwetting and drooling.But what can I do?I need it for survival. The mandatory bloodwork is a major inconveinence and pain in the rump.The 2 good things about it are:no sexual side effects,and good for anxiety. | M | 12 years | 12/13/2008 | 5 | Schizoaffective disorder | weight gain, night sweating | LOVE this drug. It made me normal, for the first time. I can do housework, I can work, I have a happy relationship with my family. | F | 30 | 9 months | 7/23/2007 | 4 | Bipolar rapid, Psychosis, aggressio | none, except knocks you out like a rock | prev on everything without success. currently Clozaril (cloment) with tegretol and epilim. brought down aggression and severe psychotic episodes from 4-6 p/week, to only once every 2 weeks or so. Currently on 75mg p/d. | M | 32 | 2 years | 4/3/2007 | 5 | psychosis | sedation, weight gain, memory problems | works great on positive psychosis symptoms | F | 23 | 1 years | 7/17/2004 |
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