| Key to ratings for lupron: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine. |
| Rating | Reason | Side Effects | Comments | Sex | Age | Time Taken | Date Added | |
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| 4 | Prostate Cancer | Very sleepy and fatigued at different time periods of the day, especially after eating.Weight gain (32 pounds in 34 months), increased appitite, cold & hot flashes,some insomnia, irritable | Upon turning 50 my PSA WAS 53.6 and was diagnosed with stage 3 prostate cancer with a gleason score of 9. I recieved lupron and casodex for 34 months and 10 weeks of external beam radiation (imrt). My PSA went down to 0.02 and stayed there for about 6 to 8 months after the treatment stopped. After that it began to double avery 3 months at first, then after about 18 months it went from 6.4 to 15 in 6 weeks. I am now on both drugs again. Have been on them now for 6 weeks as of 11/16/09 and have not recieved the results of the blood test taken the other day. I am also trying MMS. Would like to find other choises as i am told my cancer is not cureable. | M | 50 | 34 months | 11/19/2009 | 5 | Fibroids | some hot flashes, but that's about it for me. | This gave me my life back! I went to ER with SEVERE abdominal pain and bleeding. I had sever anemia. I had to have blood transfusions it was so low. I was given the 3-month Lupron shot and after about 1 week my bleeding totally went away and the pain was gone. I was able to go on my scheduled Caribbean Cruise because of Lupron the next month. Without it I would have had to cancel it. This is temporary until I have my Fibroids removed. Moodiness and insomnia - I had these before I took Lupron. I highly recommend it, but realize that side effects are different for everyone. | F | 39 | 1 months | 11/18/2009 | 5 | Severe Endometreosis | None | I was put on Lupron for severe Endo as a last ditch effort before a hysterectomy. I received 3 injections and it has worked beautifully - no mood swings, no hot flashes, no night sweats..nothing and the pain, heavy bleeding and bowel/bladder problems that I had from the endo are completely gone. I was hesitant to take the drug from all the negative feedback but I have to say I experienced none of the issues that others have complained of. I would recommend it to anyone with a similar problem. | F | 49 | 3 months | 11/13/2009 | 1 | uterine fibroids | hot flashes, vaginal dryness, all the little things they warn you about. THE MOST IMPORTANT THING THEY DID NOT EMPHASIZE WAS RESULTANT OSTEOPOROSIS!!! Do not take this drug. It is poison to your body. Do your own research, find a doc who will work with you. If a doc suggests Lupron, for any reason, to any person, man or woman, run, run, run! The problems you will deal with later in life because of this poison, are far worse than the symptoms you are treating now with Lupron. If you have already received the injections, start taking calcium and vitamin D now and don't stop. Also, get a bone density scan done! Every two years if you are found to have osteoporosis. Good luck to all who have become Lupron Victims. | F | 49 | 3 months | 11/13/2009 | 4 | endometriosis | during treatment: constipation, hot flashes, acne, sleeplessness | Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice. When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days. It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain. Did anyone continue expe | F | 28 | 6 months | 11/12/2009 | 3 | ER positve Breast Cancer | I am taking Lupron as part of the Hormonal Treatement plan instead of taking Tamoxifin. Lupron as put me in "menopause" and enables me to take Arimedax for Post menopausal treatment. I have received the Lupron injections since 9/2005 and have no periods since. Would prefer not to be on this med as I am very concerned about the 'long-term' effects. | Pros: no periods, No Breast Cancer!! Cons: weight gain especially in the mid section, water retention, insomnia (very bad), joint aches, back ache, hot flashes, and real difficulty with an exacorbation of depression with irriatability, low mood, some mood swings, impatient. This has been the most difficult piece with this medication. You really have to weigh the pros and cons as it can become a quality of life issue. For me it is Lupron with Depression symptoms and knowing that it is not likely that my Breast CA will return or stopping the med and concern of a reoccurance. | F | 35 | 4.3 years | 11/12/2009 | 1 | endrometrios | It was the worst, I experience the worst side effects that any medicine should be allowed to have. Extreme mood swings, Intense hot flashes and night sweats frequently, extreme weight gain(15 lbs)within 2 months and still trying to lose it...hair loss and foggy mind. I went to my general practioner and he described Wellbuton to counteract the Lupron. I will deal with the pain when ever my cycle resumes. | M | 44 | 3 months | 11/12/2009 | 1 | endometriosis | debilitating bone/joint pain | Please use this drug with caution. My last injection was over a year ago, and my pain is still severe. I have seen three specialists and have undergone extensive testing. They have all reluctantly agreed that the Lupron is causing my pain. | F | 31 | 5 months | 11/12/2009 | 1 | prostate cancer spread to bones | My father had three injections and became very fatigues and depressed. He took his life a month and half after the last injection of Lupron. He had a heart condition also and was given the drug anyway. It has been shown to cause cardiac arrest. THe nurse practioner at Thomas Jefferson Urology in Philadelphia, PA said she saw my father was depressed and she continued to give him the injections. She was not supervised by an MD which is permitted in Pennsylvania. Before the shots, father was walking around Philly. After he was too tired and depressed to do anything. Nurse also gave him Casodex which combined with Lupron severely lowers testosterone levels. Dr. Sui-Long Yao of Cancer Institute of New Jersey did a study that shows Lupron doesn't increase lives of prostate cancer people and seriously damages the quality of their lives. The Los Angeles Times newspaper reported those receiving Lupron had a 17.4 percent death rate vs. those not receiving it of a 19.9 percent death rat | all of his teeth would have to be pulled because Zometa causes decay of the jaw bone. She said my father didn't want that to happen to him and she didn't refer my father to anyone else for chemotherapy when he asked if there was another course of treatment. She let him leave very depressed and tired from the Lupron and Casodex. The supervising doctor, Dr Goldman, of the nurse practioner, nurse Darlene Bewick,said to me he didn't know about my father's care because the nurse saw him. he didn't even know my Dad had bone cancer from the prostate. Do not take Lupron. It causes severe damages and has caused my father's death. Doctors keep giving the drug. Please email me: Cheryl. | M | 88 | 4 months | 11/8/2009 | 4 | Endometriosis | Hot flashes, real bad muscle aches, nausea, headaches, mood swings, fatigue. | I had an ovarian cyst removed in May 2009, when the doctor found some endometriosis. Started having real bad symptoms of the endo in August, got my first Lupron shot at the end of September and I just got my second shot four days ago. I saw my college's health services today because I thought I had the flu, I'm so achy and exhausted, but I don't have a fever or anything so I think they're likely symptoms of the lupron. I am on the pill that came with the shot, take that every morning and I think its better with that because I missed one once and I was MISERABLE. I think I've had "hot flashes", in the sense that I sweat more than usual and sometimes feel very warm, but nothing like older women I know who are actually going through natural menopause. I feel TERRIBLE today, but I guess body aches is better than being doubled over in severe abdominal pain every other day? | F | 20 | 1 months | 11/3/2009 | 4 | Lower Androgen level | mood swings, hot flashes, night sweats, headaches, nausea, light-headed, 1st month still got period | I took 2 one month injections to lower my androgen (testosterone) levels- it was high for me being a female. After 2 months it was lowered and I am supposed to check it again soon, so hopefully this works long-term. All of the symptoms were relatively mild and not all the time. However, I felt pretty weird and out of it the whole time. I did a lot of research online and there are a whole lot of horror stories, but it really wasn't that bad for me. I lived with someone else who took it for inducing menopause and she had more severe symptoms. She was also on 3-month doses and said they stayed in her system too long. If my levels continue to stay normal long-term, this was well worth it and I would do it again, but not for any extended period of time. | F | 23 | 2 months | 10/29/2009 | 4 | Fiboids | Hot flashes. Mood swings. Spotting at first and then no period at all. Mostly hot flashes. | I have a 17 cm fibroid. I am taking a 3 month injection to shrink the fibroid to Da Vinci operable size. PLEASE look into the Da Vinci surgery. The recovery time is 2 weeks and is much less invasive. Most doctors don't know how to do this surgery. Keep searching until you find one that does. | F | 34 | 6 weeks | 10/18/2009 | 1 | Uterine Fibroids | I started having hot flashes at the age of 32. Hot flashes, rapid weight gain, vision changes, acne, muscle and joint pain, extreme aggitation, heart palpitations, thoughts of causing others harm, short term memory loss, diagnosed with high blood pressure and arthritis, dizziness, shortness of breath, chest pains, looks like I am 5 months pregnant, and a daily migranes are all that come to mind at the moment. BUT I am sure the only reason I can't name more is because of the memory loss. | Poison to body and soul. The temporary relief is NOT worth the long term suffering caused by Lupron!! I suppose the only thing that may make this nightmare worth it is if you are trying to conceive or you are being treated for a terminal illness. I am praying for all of us and even those that have read all of these posted warning and unwisely allows your doctor to convince you to alter your life forever. I only had fibroids and now I feel like an 80 year old woman. My daughter wants to know why I don't play with her anymore. Every day I have to tell them to be quiet because mommy doesn't feel good today maybe tomorrow. The Devil is a lie, I am going to play with my girls again. In the name of Jesus!!!!!!!!!!! | F | 45 | 3 months | 10/12/2009 | 5 | Endometriosis | Joint Pain, weight gain, hot flashes | I was on Lupron in 2001 for my endo pain and i LOVED IT! My pain was gone and although the side effects weren't fun it was worth it. I had a son in 2004 and 2006. I started feeling endo pains last year and I talked to my doctor about another round of lupron. I just got my 1st 3 month shot this week and i am excited. Think about it - i got the shot in 2001 and started feeling pain again in 2008? Seven years of relief! Lupron is wonderful and I say try it! | F | 29 | 6 months | 10/9/2009 | 3 | Anomiosis and Stage 5 endo | I gained weight, always tired, horrible horrible mood swings, anxiety, depression, always crying, bruise easily, acne wich I have nver had in my life. | I am 21 years old I started the lupron injections five months ago because I have anomiosis amd endometriosis.I have been sick since i was eleven. I have had five surgeries nothing has helped so lupron was the last thing to try. I am on a low dose of it. I absolutly hate it. I thougt i was getting better but this month which is my 5th month is bad Im in costant pain. Im very emotional. I just feel so slow and depressed. Im only on it another month Im just wondering what happens when I go off. | F | 21 | 5 months | 10/9/2009 | 3 | ENDOMETRIOSIS-PCOS | MIGRAINE, JOINT PAIN, BLOATING | I have taken 1 3 month shot and due for my second. At first, my symptoms of endo were really bad if not worse then I have noticed in the last couple of weeks that the pelvic pain is gone but the joint pain and abdominal bloating are my biggest problems now. I had a couple of migraines the first month but none since then. over all I think Lupron has helped with my endo but I am now concerned about joint pain and the swelling of my tummy. I plan on seeking advice from an endocrinologist (not sure if I spelled that correctly) since I have PCOS as well. Also will be making an appointment to see a gastroenterologist to check out the bloating. | F | 35 | 3 months | 10/5/2009 | 1 | endometrosis/ pelvic pain | I only got the shot 5 days ago and i am experiencing many side effects. Hot flashes and cold sweats started the day after. I have been very dizzy i can get half way through straightening my hair and have to sit down. I have ate 1 can of chicken noodle soup,6 saltine crackers, and a half a sandwich in the last 5 days. I have also had a very very bad headache the last 5 days. I have missed two days of work this week because of how nausiated i have felt which started the day after the shot was givin. | This was only my first shot and i am already having so many problems with it. I dont think i am going to continue getting these injections because i am afraid the more i put into my body the worse it will get. | F | 20 | 5 days | 10/4/2009 | 1 | severe endometriosis | Debilitating joint and bone pain. After taking 1 three month injection of Lupron, I have since been diagnosed with Rheumatoid Arthritis and the blood disorder Polycythemia Vera within a year. It did stop my cycle for 6 months so I did have temporary relief from the endo. | I do not recommend this drug to anyone. Even with an add back. Especially anyone that already has a anti-inflammatory disorder or disease. I never experienced such adverse side effects from a medication until Lupron. Horrible. | F | 36 | 3 months | 10/2/2009 | 1 | endometriosis | Hair loss, memory loss, severe hot flashes | I will say that after I was off Lupron, I got preganant 5 months later. However, I would NOT recommend Lupron. This drug put me into early menopause the second I got off it. My docs have said that my body is actually 15yrs older than my age. I have very little short term memory, my hot flashes have never gone away and my last shot was 18 yrs ago. Now my daughter has started having hot flashes at the age of 14 and strongly believe it was because of the Lupron still in my system. I had endometriosis so bad that the doctors filmed my surgery and took it around the world for training classes. Ladies, get the hystorectomy!!! Yes, you'll feel better, still lose your hair and so on. If you have endo, don't keep the ovaries because the endo will still live. All the pain is gone except for the side effects of the Lupron. Several years ago there was a class action law suit againt the use of Lupron. You had to sign up for compensation however all the news regarding this just stopped being posted. I gave up and figured I got my daughter and will just deal with the worst of it the way I always have. If you can survive ENDOMETRIOSIS, you can survive anything! Can I hear an Amen?? | F | 46 | 6 months | 10/1/2009 | 5 | Endometriosis | Hot flashes, easily irritated, more emotional | I have to ask myself why I put off taking this drug for so long. My pain was so bad, I was miserable and my quality of life sucked. I rarely went out with friends and was no fun to be around because I was in constant pain. Within just a couple of weeks after the first shot everything changed. I feel great. I had forgotten how great it is to not deal with pain everyday. My doctor started me on the 30 day shot to ensure I could manage the side effects. I waited exactly 30 days to get the 2nd shot and 2 to 3 days before the shot I started to experience pain and other symptoms associated with my endometriosis. We opted to do the 3rd shot earlier and I experienced none of my previous problems. My doctor is only keeping me on a six month treatment and I can only hope that the medicine builds up and I get the years of relief that have been reported with this medicine. I can't imagine having to go back to the way I was before. I feel like a different person. I am able to go out and have fun with my frieds, I went on vacation, and get along better with my family. I consider it my miracle. | F | 31 | 60 days | 9/29/2009 | 5 | Endometriosis | I had experienced none of the side effects that was listed in the patient drug information. I guess the only side effect was pain relief!! | I have nothing bad to say about this drug other than I would like to take it more frequently. it has done wonders for my pain, and I would do it again if the doc said I could. I did it for nine months. has anyone ever done it longer? I LOVED it. | F | 32 | 9 months | 9/20/2009 | 4 | shrink fibroids before hysterectomy | minor headaches, weight gain, mild depression, fatigue, hair loss, hot flashes | lupron successfully reduced the size of my fibroids allowing my hysterectomy to be VLAH instead of abdominal. this has been fantastic - today is 6 days post surgery and i can walk 2-3 km comfortably, have 3 insignificant incisions, very little pain and could reasonably return to a desk job within another 7-14 days. being informed of the side effects is important to be able to manage through them. my doses were 1 shot/month for 3 months. last shot 2wks ago - hair loss just started - i lost hair post partem also likely related to hormonal swing so it makes sense. | 3 months | 9/20/2009 | 3 | Endo, Fibroids | Moodiness, weight gain, fatigue, depression, vaginal dryness (severe), decreased libido (significant), constant spotting, abdominal cramping | I started taking this medication about 3 weeks ago. Since then, I have been spotting/bleeding nonstop - this has been the worst side effect for me so far. Some days it is lighter than others. I am always tired and very irritable. I had very little symptoms in the first few days of receiving the injection. Thankfully, my doctor also prescribed aygestin to help with the hot flashes and it has worked exceptionally well. If you are considering taking this shot, I would recommend asking the doc to prescribe something in addition to combat them. I hate the way it makes me feel most of the time and I cannot wait for the next few months to go by so I can be finished with it. | F | 26 | 3 weeks | 9/10/2009 | 3 | Endometriosis | Hot flashes, night sweating, severe mood swings, depression. | I started taking Lupron two weeks after I had a laporatomy in December. I took six shots and told the doctor that i refused to take anymore. I was so moody and depressed that my husband was miserable, almost left me. I had to start taking Welbutrin for the mood swings after my second shot. All I did was cry. I took my last shot in May and did not get my first period since the surgery till August. AFter the period, I am having to take birth control non stop till I decide when I want to start having children. I would recommend the shots to anyone, but be sure you have a doctor that is very open with you and be there to answer your questions if you have one. If I had a question or problem, my doctor or his assistant always called me back and I did alot of research before I took the first shot. Also, I got some advice from some friends who had been on the shot and kinda knew what to look for. The only problem I am having now is that my legs and ankles started to swell in July. My left leg/foot is swelling worse than my right. I have been checked for several different things and nothing has been found. I am starting to wonder if it is a side effect for quitting the Lupron. If anyone has ever had this same problem after the last shot, please let me know. | F | 28 | 6 months | 9/10/2009 | 3 | Excessive Bleeding/Pain | Hair loss, lots of it. migraines, decrease libido, vag. dryness, | I havent had hot flashes yet, however, Ive only been taking this for one month. I still have grave concerns over what happens after the completion of this medication. And i really hope I still have hair left after this is all over with. Other than that I still think its working well. | F | 37 | 1 months | 9/8/2009 | 1 | endometriosis | Hot flashes, Lots of hot flashes, brain-fog, severe moodiness, Extreme forgetfulness, Weight loss, | At the time was taking it -and up to a year later, I would have recommended Depo Lupron. It helped with the pain of endo. for the 1st time in my life I wasn't doubled-over in pain, and could be active! But the side effects still continue and the pain comes back. 7 years later: I'm VERY forgetfull/ memory problems, to the point it's cost me friendships and jobs. I suffer Joint pain, insomnia, occasional hot flashes, became very sensitive to chemicals and stimulants (such as caffeine, medications, food additives) With such complicated, long-term side effects and not being able to find a doctor who will look into what happened to me as a result of luron, the desperation now is worse than just the pain of endo. (plus pain/endo back too) I strongly warn against Depo Lupron!! If anyone has had similar problems with MEMORY and other long-term side affects please e-mail me with what's helped or info on Doctors who have looked into this. Thanks | F | 25 | 6 months | 9/8/2009 | 4 | endometriosis, ovarian cysts | hot flashes, depression, weight gain | Have LOVED not having a period for a few months. I've been virtually pain free! I don't know how long it will last once I'm off the drug but for now it's great. I've had 2 injections and hot flashes were the worst within the first couple of weeks after each one. But I have to say it's been worth it. The weight gain sucks, so I'm hoping to lose the 8-10 pounds over the next few months. I've been moodier than normal, but I learned to sort of "feel" when a bad mood swing was coming so I could take a few deep breaths or find another way to deal with it. In hindsight, maybe add-back therapy would have been good, but I didn't want to take any other medicine. I'm hoping this drug will buy me a chance to conceive. Aren't hot flashes and 10 pounds worth that? | F | 32 | 4 months | 9/6/2009 | 3 | PCOS, Endo and Ovarian Cysts | Hot Flashes, Cold Flashes, Joint Pain, Fatique, and headaches | I have only been on this for about 2 weeks and i am having so much pain in my back. The first week I was bed bound for 4 days. I got my period so bad I was going threw a pad an hour it was horrable. I am hoping that the side effects start to settle. The doctor tells me that the first two weeks things get worse then your body evens out and things start to get better. I hope he is right. I was trying everything else not wanting to have this injection knowing all the side effects and my response to meds. well that time came the doctor said you have tried everything we need to do the injection now. I went for the first 3 months being a month at a time incase my body didnt respond well. then the last 3 months would be one injection. well I had the first on on 08/19/09 and I got a hot flash with in an hour of getting the thing. I will keep on trucking in hopes that the side effects settle and this will help. I can have my period 3-4 times a month and they can be very very pain full. My wishfull out come on all this will be they find some way to make me healthy. Am I wishing to high? | F | 23 | 6 months | 9/1/2009 | 5 | Endo | Hot flashes, Insomnia, Fatigue, Mood Swings | When I got the Lupron shot, I was not informed of all the side effects. It was not until after I found this website that I learned about how much it would truly effect me. Lupron has changed my everyday life, I have hot flashes, cant sleep AT ALL, I am constantly worn out, and mood swings like I have never experienced before in my life! Even though I have so many things hindering my everyday life, THE PAIN HAS STOPPED! Which makes it all worth it to me. I went to my family doctor and explained I was on the shot and he put me on Cymbalta (which helps a ton!). I would recommend this treatment, just make sure you are prepared to deal with the side effects. | F | 20 | 5 months | 8/29/2009 | 1 | pre-op for endo/pcos | hot flashes,migranes, hungry constantly, pain in my back, get angry easily(not at all like me), I feel horrible and i have not slept in 2 weeks | I am scared. My ob said she would do 3 injections of this drug before hysterectomy. I went for first inj. saw a different dr. who said 6 months is better. After the inj. I was told about the side effects!!!! She gave me horm. replacement and told me to put off surgery. Which sounded like a good idea at the time. I am now miserable!!! I have hot flashes constantly, i don't sleep, physically and emotionally exhausted, I have horrible migranes and then headaches with pain for days!!I have pain everywhere, legs,back, my hands and wrists are swollen all the time, I am bleeding, sex is painfull(has been even before inj)but is now worse, I was losing my hair on my head but that has gotten worse, my acne is out of control, I sweat so much that I am getting rashes everywhere. I am scared and dont know what to do. I just wanted to stop living with pain and I feel that the cure was worse than the disease. I just want it to be over. The doctors alway tell me "we are going to take the wait and see approach" I want to scream at them and tell them this is all ruining my life and you want to wait and see. I don't know what to do. | M | 30 | 21 days | 8/27/2009 | 2 | Endometriosis | severe depression, extreme fatigue, cramping, heavy bleeding | So the first month has not been so great. I am extremely tired, but can't sleep. My period just showed up one day with such extreme cramping and pain that I could not even stand up..granted, not much different than before. Which is why I will continue to take the injections. I have had a laporoscopy already. Having 4 children, I would like to just have a hysterectomy, but the docs refuse to do it. My biggest thing is this...I HATE my husband. And I love my husband, so I really don't want to hate him. I just can't help it. Lupron is obviously causing some pretty severe mood swings. Hopefully I can get it under control before it causes a divorce! Email me if you are having problems too and care to talk about it :( | F | 29 | 1 months | 8/24/2009 | 5 | endometriosis and severe bleeding | The month after the first injection was bad, and I had a lot of weakness, mainly because it lengthened my period. But after the second shot, the side effects were very minimal, limited mainly to hot flashes, which are now almost non-existent. | I read the comments on this page the night before my first injection, and I cried. I almost didn't go through with it, but I am SO GLAD that I did. Lupron has been an absolute God-send. Most of the horrible side effects listed on this page are what I got when I took birth control, so I was terrified to try something else. But it has helped me SO much, and I have regained my life. I recently went from the 1 month shot to the 3 month, and my problems without Lupron are so severe, that I am taking it for ten months instead of the normal six. I'm so thankful to have it. | F | 21 | 6 months | 8/22/2009 | 4 | Fibroids | Some muscle and joint stiffness and soreness, and intermittent night hot flashes. Pain, swelling and inflammation from fibroids GONE, completely after 1.5 weeks. Noticeable fibroid shrinkage. Some insomnia as a result of the hot flashes at night after first month. Muscle and joint soreness which was helped by daily exercise. Muscle and joint side effects decreased after month 1. Hot flashes helped greatly by Estroven. | Side effects were minor compared to the pain relief from the fibroid shrinkage and slow down of heavy menstrual cycles. Huge improvement in my fibroid related symptoms. Over the counter Estroven supplement greatly helpful for night sweats. I did not get add back therapy from my doctor, but I suspect this would work more effectively than over the counter subsitutes. I was very nervous to take this medicine, but it worked! I was shocked to discover how exhausted I had been from the constant heavy periods, inflammation and pain from the fibroids. It resolves any questions in my mind regarding my planned hysterectomy later this year - it is absolutely necessary. My multiple fibroids had grown to the size of a 6 month pregnancy prior to taking the lupron. I will not hesitate to take my second 3 month dose of lupron. | F | 41 | 3 months | 8/17/2009 | 5 | Endo Stage IV | Hot flashes, sleeplessness, weight loss | Had laparoscopy. A lot of small chocolate cysts, adhesions and scar tissue removed. I'm on Lupron for 4 to 6 months then moving to IVF. I've had 3 injections so far. Overall, I feel better than ever. I'm almost nervous to go off of it. | F | 35 | 3 months | 8/12/2009 | 2 | breast cancer(male) | tired, no libido, some night sweating, no energy, weight gain | Was on this medication after chemo ... broke out in hives and had terrible joint pain ... Dr. took me off for 6 mo. and now we have started it back ... once an month shot ... tiredness is back and joint ache is back ... no hives as of yet... some vision related issues foggy, with some slight diziness | M | 59 | 30 days | 8/11/2009 | 5 | Fibroids and Menorrhagia | Hot Flashes(sometimes severe), Mild Joint Pain, Brain Fog (the most anoying side effect for me), Mild Acne, and I'm a bit quicker to get angry | Wow - been an interesting ride - last posted after my 2nd shot - I am the woman who was bleeding to death because of fibroids - I have had my 4th now and my fibroids shrinking so rapidly that my OBGYN thinks she can control my bleading with nothing more than Yaz after I'm done with the 6 shots. One note - after my 3rd shot I had a week where I ached all over like a really bad flu - but other than that I've had not problems that would stop me from finishing this series of shots. The brian fog is bothersome, but it comes and goes and I am still maintaining a 4.0 in my master's classes - I just have to work a bit harder at it now. So, I don't know about endo or trying to get pregant, but I can tell you that, for me, Lupron did what I was promised and I am very glad I'm taking it. Will post again at the end of this series. | F | 47 | 4 months | 8/10/2009 | 4 | Endometriosis stage IV | Decreased Sexual Desire, Hot Flashes, Aches and Pains, Tender Breasts | My endo was discovered in 2004 and I have had lupron on and off for the last 5 years. The total time I have used lupron is around 2.5 years. I have been put back on it and the gyno has told me that I can continue to use it until decide to have children. I prefer lupron to my periods but I am becoming concerned about the long term use of the drug. A few weeks ago I noticed that my left breast nipple is very swollen/tender and my mom is concerned. In the short term, lupron may be a good pain reliever but I am concerned that the lack of hormones could be causing other problems. | F | 23 | 3 times | 8/10/2009 | 3 | Stage IV Endometriosis | Increase in migraines, joint pain, but no other side effects other than being cold for the first time in awhile! | So far, I love it. It has helped level my mood, controls my hot flashes that I started getting after my Laparotomy, and I don't have to deal with my period now for a while. UNFORTUNATELY, the pelvic pains have not gone away, and the ovarian cysts are starting to come back less than 3 months after having them surgically removed. | F | 25 | 2 months | 8/9/2009 | 3 | Stage IV Endometriosis | So far so good. I was told side effects may not start until second injection. | I have stage IV endo that has caused lots of physiological issues such as multiple blood filled cysts, a blocked fallopian tube, colon issues, and pain everyday when I wake up. I started going through the process of getting it removed so my husband and I can hopefully have a baby. I had a laparoscopic procedure but since endo bleeds so much and the issues with my colon and the endo growth, the dr. could only clean up one side. I'm on lupron for 5 months to slow the growth so he can hopefully clean up the other side and we can get pregnant. I've been scared to death to take this for years but I had my first injection 2 weeks ago and everything is going fine so far. I'm actually having cold flashes... kinda odd! I still have mild endo pain but I'll take that over some of the things I've read about on here any day. | F | 28 | 2 weeks | 8/1/2009 | 4 | Fibroids causing anemia | Some hot flashes. A little fatigue, complete loss of sex drive. a little foggy in the head. Weight gain maybe - not sure?? | I was freaking out after the dr. prescribed this for me. Begrudgingly I took the shot. I have 2 submucosal fibroids which are about an inch around. The worst side effect I experience is the fogginess. I search and search for the right word and it never comes. The pros far outweigh the cons - this drug has turned me around to prepare for myomectomy. I was bleeding so heavily before lupron that I had to receive a transfusion. I was in and out of the ER. Long story short - I have since switched drs. New dr will do myomectomy and hysteroscopy (yeah!) Old dr. wanted to "try out" different birth control pills which do not work because fibroids have more estrogen receptors than normal uterine tissue and they feed off of those pills and just grow and grow. I am off of bcp's, and on my 2nd injection - the bleeding has stopped completely. It took a few weeks for that to happen. After the first shot, you should get a period within about a week. Mine lasted for about 4 days, tapered off to nothing. NO MORE BLEEDING!!! The reason for this is your uterus is shedding all of the extra stuff that has built up. I just had the 2nd shot last week and my stomach is now flat and I have no more fibroid pressure. I literally feel like my uterus (which was enlarged) is smaller. I really think the key is to exercise every day, take your iron, calcium and daily vitamin and REALLY watch what you eat. Yes, it is a lot of work, but I have not gained an ounce, in fact I have los | F | 35 | 6 weeks | 7/29/2009 | 2 | Firbroid and heavy bleeding | Extreme joint & muscle pain, hot flashes, nausea, big mood swings and fatigue. | Did NOT shrink my fibroid which is the reason I was put on it...did eventually stop periods in the 3rd month. Still need surgery after all the side effects. | 42 | 3 months | 7/24/2009 | 3 | ovarian cyst and endo | hot flashes, depression, anxiety, night sweats and bad acne break outs | i wasnt very excited to start on lupron because my mom suffered from endo and cysts so she warned me about all the crazy side effects. This is a very powerful lil shot! | F | 22 | 3 months | 7/23/2009 | 4 | Endo and ovarian cysts | With lupron I have night sweats, joint pain and depression... other than that i am doing AMAZING!! | I was so scared to start Lupron because of all the negative things i have read about it. But for me I am not dealing with anything i cant handle. if it gives me a chance to try and have a baby before a hysterectomy is needed then i will gladly take whatever symptoms. The only things that really sucks is the joint pain and stiffness... but i try and do more stretching to help. | F | 22 | 2 months | 7/19/2009 | 3 | prostate cancer | hot flashes, loss of libedo, fatigue, liver enzymes ( ALT, AST doubled tho I was also on simvastin. Am now working to see if it is the simvastin or the lupron that is involved | Exercise definitely helps. I had 3 mo lupron, then combined with 42 radiation treatments; will be on lupron 1 year at least. Side effects are manageable, PSA now (6 wks after radiation) ay 0.04. | M | 72 | 7 days | 7/19/2009 | 4 | Severe Endometriosis | Hot flashes, some moodiness, decrease in sex drive, weight gain, some acne | I have been on the medication for over one month and feel great. I have gained some weight (about 3-5 lbs) and have some acne (but this may be a result of getting off of the birth control pills since I've always had bad skin). I have some hot flashes. I was so scared to take this medication after reading some patients' comments, but I truly feel fine. Hopefully this will one day give me an opportunity to have babies. HIGHLY recommnend asking your physician for add back therapy. I truly believe the pill I take once a day is the reason why my side effects are not as bad as some of the ones being experienced by others. | F | 27 | 1 months | 7/13/2009 | 1 | Endo | severe side effects such as severe mood swings, hair loss, and loss od sex drive. | F | 27 | 5 months | 7/12/2009 | 4 | Fibroids, heavy bleeding | Hot flashes, pressure in my head, depression, menstrual cramps, sweating, increased sex drive, vaginal dryness, forgetfulness | I never had menstrual cramps before until I took this medicine. Sometimes I would be in intense pain, which would last for about 10 minutes. I haven't had a cycle for the last 2 1/2 months, which is good cause I had them twice a month before Lupron. The pressure in my head and dizzyness was almost unbearable, but has gone a way. I'm in my third month and some of the side effects are starting to ware off. I'm glad I took the medicine despite the side effects since it gave me a three month break from my heavy twice a month cycle. Hopefully I won't need surgery after the three months is up... | F | 27 | 3 months | 7/8/2009 | 1 | Huge Cervical Fibroid | Non-stop migraine headache from time of injection, continual bleeding/spotting, acute constipation, severe acne, severe increase in bulk symptoms, joint pain, forgetfulness, foggy-brained, severe mood swings (extreme anger/suicidal depression - NOT KIDDING), itchy skin, hot flashes, loss of maternal instinct (DID NOT SHRINK MY FIBROID - Don't let your GYN dupe you! Cost/Benefit analysis? Just say NO.) | DO NOT TAKE THIS DRUG. | F | 31 | 4 weeks | 7/7/2009 | 5 | Precocious Puberty | Has nearly stopped precocious puberty side effects. | My 10-year-old daughter has had Lupron injections for 23 months now. (She was cocaine exposed in-utero, which we believe is the primary cause of the precocious puberty.) Her dosage has increased 3 times over the 2 years. Her developing breasts disappeared, her extreme mood swings are dramatically reduced, PMS symptoms gone, migraines gone, she's gained 5 inches in height, and her bone age is now nearly her real age (not 50% older). On the other end of the spectrum, I'm just finishing menopause (no Lupron) a little younger than the average woman, and am experiencing much of the symptoms many women who hate the Lupron are experiencing. Huge hormone changes can be a nightmare, whether drug or nature induced. | F | 10 | 2 years | 6/29/2009 | 1 | Endo | Feeling out of it,Dizzy, Headaches, joint aches, depression, moody, acne.. did I say depression?? | I am going back to my painful cycles, these side effects are worse to me because they are constant, not 2 weeks out of the month.. | F | 28 | 1 months | 6/22/2009 | 5 | Endomitriosis | No side effects. I felt great the entire time. | I felt great when I was on Lupron. I didn't have to worry about pain, cycles, or blood. I would suggest the add back therapy to help even out the hormones. | F | 21 | 12 months | 6/19/2009 | 4 | reduce estrogen for more growth | HOT FLASHES!!! | im very pleased with this medicine. without lupron my adult height would have been 4'5 but thanks to lupron i am now 4'11.75 which is taller than i could have ever hoped for. the hot flashes were a pain but it was worth it. | F | 15 | 2.5 years | 6/17/2009 | 3 | prostate cancer | Hot flashes, major memory loss, severe depression, anger, breast development, lethargy, no motivation to work | I trust my doctor that it's the right treatment, but I hate the side effects and can't wait for the treatment to be over. I've been taking it for 2 years; 3 years to go. I've had radiation and brachytherapy. At diagnosis, my PSA was 25 and my Gleason score was 9. PSA now 0.03. | M | 58 | 2 years | 6/15/2009 | 3 | endo | hot flashes,night sweats, mood swings, hair loss, memory loss, headaches, joint/muscle pain, loss of sexual interest, extreme vaginal dryness. | My last injection was May 1 (total of 6). I am still experiencing almost all of the side effects mentioned. It has been a long, hard 6 months, but not totally unmanageable. If it reduces my endo enough to allow for pregnancy, then it was worth it. | F | 32 | 6 months | 6/15/2009 | 5 | Stage IV endo | very mild hot flashes but those didn't start until the 2nd month. Slight decrease in sex drive. First month I was more tired than normal and had some headaches but both went away. | I was so nervous about taking Lupron and I avoided it at all costs because of what I read of other people's experiences. What I've learned is that you have to rely on your doctor and don't assume you'll have a terrible time with it. Some people do but that doesn't necessarily mean you will. I am a professional classical singer and I was worried about what it would do to me vocally and I've been fine. I'm also a triathlete and I was terrified of weight gain and joint pain but neither one have been a problem. The pain from the endo is GONE and that's worth so much to me. I have it everywhere - on my colon, small intestines, in my left ovary, you name it. The pain was making my energy worse than the Lupron. I told my husband that if I could stay on it I would. After my 3rd shot next week, I'll have one to go. Do your research on the drug and find a doctor you trust. | F | 36 | 2 months | 6/11/2009 | 4 | endometriosis - severe pain | some moodiness, swollen breasts but that's subsided, fatigue, a few hot flashes | I have every intention of continuing my Lupron treatment. It is definitely working. I'm 44 and my first shot put me into immediate medical menopause. . .yeah! I have a few endo twinges but that's about it. This medication is a God send for me. | F | 44 | 1 months | 6/10/2009 | 5 | Fibroids and Menorrhagia | A couple of mild hot flashes, and some moodiness (a bit quicker to cry at a sad movie, but nothing severe) I also have a bit of joint pain, but I'm not sure if this is directly related to the shot or is because I've been getting up and walking more since I'm not as horribly anemic. | I was terrified of starting this treatment because of all the negative reports I keep seeting, but I am so glad I did. Before lupron I was bleeding to death with 18 out of 28 day menstral cycles. Since I started lupron, I've only had one cycle, and it was mild compaired to what I used to have to deal with. I will come back and post again if I have start to have problems, for for now, this has been a life-saver. | F | 47 | 2 months | 5/29/2009 | 4 | Severe Endometriosis | I have gained weight and I hate it but I have no periods which I love. I am slowly but surely getting my sex drive back. My breast are huge but beautiful. :-) Seriously, I've been on Lupron for about 2 years. I had a serious talk with my GYN regarding how long I can be on this medication and what alternatives that I have. You see I have BiPolar I and a Seizure Disorder so a Dr. is not treating just one issue he/she is treating a co-morbidities. Before when I was not on the Lupron and I was on my cycle there were a couple of times or more than a few times than a few times I went into a manic state so the Lupron right now is giving me a repreve. Right now a hysterectomy is not an option. | I've been doing pretty well for the last two years all things considered. I don't want to stay on Lupron forever but I don't want to go back to having my cycle either which turned me into my manic state which in one case landed me in the psych ward because of my bipolar and endo combined. So you see each person is different and you can only do what's best for you. :-) | F | 36 | 2 years | 5/29/2009 | 5 | Severe Endo and Tumor in uterus | I have NOT had a horrible experience with Lupron, I was so scared by all the info on here about all the side effects. I have just started my 7th month of treatment, I am doing 1 year of 3 month injectons. First few weeks were rough but everything was fine after that. I have a few hotflashes when I get the shots but they go away. I do have a lot of nightsweats, usually 2 or 3 a night, I also have lost my libido, thank god for some helpers in that area! I also take the add back and when I forget for a few days...you dont want to be around to see what happens! I did have a lot of joint pain for the first month, I could barely walk up the stairs. I started taking 1 tylenol arthritis for it and I am totally fine now. Some of the crummier side effects are the loss of sex drive and the vaginal dryness, and the weight gain. I just feel like Im a lardo all the time. But I am very happy I have taken this drug! Everyone reacts different, please talk to you Dr. and get all the details before sayi | My Dr. found a very large mass in my uterus and when he went in to take it out he also found that I had severe Endo. He wanted to do a hysterctomy right then, thank god my husband told him no way! ( we do not have children yet)after the Laproscope I started the Lupron Depot to help with the endo and to shrink the tumor so they can take it out. | F | 29 | 7 months | 5/27/2009 | 1 | OVARIAN CYSTS | Gnawing bone/joint pain, osteoporosis, osteoarthritis in all paired joint, neuropathy, blood disorder, autoimmune disorder | I wouldn't recommend this drug to my worst enemy. If you would like this drug taken off the market or at least its use limited, please go to: WWW.Petitions2congress Letters will be sent to your Congressmen and President Obama | F | 38 | 2 months | 5/27/2009 | 1 | Endo | Weight gain, could not control emotions, persistant bleeding, loss of memory, Severe bone and muscle pain, pituity gland shut down, within one year of last injection diagnosed with autoimmune disorder | Please, do yourself a favor, don't take this drug no matter how wonderful you think your GYN is. Taking this was the worst thing I could have done to myself. 4 years later and I still have problems brought on by this drug. Please, don't be fooled by your GYN like I was!! Two, 3 month injections.. | F | 44 | 6 months | 5/18/2009 | 2 | endo | constant headaches,dizzy,very tired,acne and depression | i feel awful. i want this to be over. i have had 2 surgeries and my only other option was to get a hysterectomy!i'm supposed to to stay on the shot for 9 months but i don't know if i can last that long! why me??? | F | 34 | 4 months | 5/15/2009 | 5 | Stage III Endometriosis | I had some hot flashing and night sweats, but it was sooo worth it! I was so scared to go on Lupron b/c of all of the horror stories I hear, but it was awesome. I am also very sensitive to hormones and can barely tolerate the moodiness from birth control. Lupron was actually better from me than birth control. I experienced less moodiness. I can't say enough good about this drug. Don't let people scare you. Everyone is different, but as a rule in general, people that are getting along with a medication aren't going to take the time to review it on the website. Go for it! | F | 28 | 6 months | 5/14/2009 | 3 | Stage 4 Endo | Hot flashes, night sweats, mood swings, anxiety, depression, edema | As my doctor warned my husband after I had lap surgery, Lupron can cause mood swings bad enough to cause a divorce in a seemingly happy marriage... THIS IS COMPLETELY TRUE. The mood swings I have are so sudden and drastic, it's like being a different person for 6 months. I neither recommend or caution against this medication, but you have to be prepared for what is to come! Please email me if you are experiencing these same problems, I would love to correspond with someone who understands! | F | 27 | 3 months | 5/13/2009 | 3 | endometriosis | hot flashes & weight gain, no periods. Uncontrollable appetite. | Pain was relieved somewhat after a few weeks. Hot flashes were almost unbearable. My last shot was two months ago and the hot flashes are now gone and the pain is back. I'm hopeful that the 10 pounds goes away soon as well but I'm not holding my breath. | F | 32 | 2 months | 5/13/2009 | 3 | Endometriosis | Long-term side effects after treatment had worn off. Lupron did what it was supposed to, I got all of the expected side effects which were bearable. But the week the Lupron should have been out of my body, I got severe symptoms that have lasted almost a year. | The side effects while I was on Lupron were really not that bad because I had read up on it and knew what to expect. The add-back therapy with it helped tremendously! The only thing that affected my life significantly was short-term memory loss and now a whole list of symptoms that seem to have been caused by the treatment. If anyone has had long lasting anxiety, depression, palpitations, dizziness, fainting,etc. after finishing treatment PLEASE e-mail me. It has to be from this shot. | F | 22 | 7 months | 5/7/2009 | 4 | Stage IV Endometriosis | Hot Flashes, Insomnia, weight gain in the belly - but not bad at all considering the mess I was in before. | I feel women should really do their homework and decide what is best for YOU. The side effects for me are really not bad at all and considering I had a 5 hour surgery to remove huge ovarian cysts and had such horrible endometriosis they had to remove my appendix and I had a 9 day stay in the hospital....follow up ultrasounds have shown that the Lupron has been effective in the treatment so I am thankful!! :) | F | 36 | 3 months | 5/5/2009 | 4 | Endometriosis, Polycystic Ovaries | Muscle & join pain, memory loss | Definitely worth it. I was in severe pain to the point of vomiting and peeing my pants before I tried Lupron. | F | 27 | 6 months | 5/4/2009 | 4 | Endometriosis/Fertility | Muscle aches in my legs after injection(goes away after a day or so) hot flashes, night sweats and minor headaches. | I just had my second shot (getting them monthly) and side effects are mild. After the 1st shot the pain was much worse but it lasted only about three weeks. Now everything is great, no pain no weight gain. I do recommed drinking a lot of water and also exercise on regualr baises. If you take care of yourself and eat healthy I firmly believe that will help reduce the side effects of deppression and wieght gain. I'm actually loosing weight!! | F | 30 | 2 months | 5/4/2009 | 4 | Prostate Cancer/surg/rad/ | frequent hot flashes followed by cold flashes. Extreme fatigue, body ache legs and back, depresses or down. Tend to be emotional. Increased appetite -gained 16 pounds.Stomach often feels bloated when empty. Some stomach ache. Short term memory loss mostly since the shots. | I took three shots in 08 three months apart. Last was Oct. My PSA has stayed down to .002 ever since the first shot. Last test last month. I have had prostate surgery, 4 years later 37 radiation shots, but 4 years later it came back. The Lupron has controlled the cancer to this point. I will put up with the side effects for it benefits. I had a knee replacement 90 days ago and that pain is also involved. | M | 72 | 13 months | 5/1/2009 | 4 | Prostate cancer | Fatigue, loss of libido, intense feeling of warmth in extremities | My PSA level was 25 (Gleason scores of 7 and 8) three months ago. A CT scan and MRI showed lymph and bone lesions in the pelvic region. After extensive consultation with my oncologist, he prescribed Lupron to shrink the prostate and shut down testosterone production. The side effects are tolerable, just annoying, and the PSA level has dropped from 25 to 3 in a month. It is also necessary to have a baseline bone scan to monitor calcium loss and other possible chronic issues, which will mandate frequent (perhaps even monthly once the Lupron treatment ceases) blood analysis and inconvenience. After 8 months on Lupron, no further androgen ablation therapy will be used until PSA levels begin to rise again. My oncologists stresses the importance of trying to maintain as normal a life as is possible, with deliberate efforts to exercise and stay active. I no longer have to take ten Ibuprofen tablets a day to relieve the stinging lesion pain enough to sleep at night. My oncologist suggests that, while he sees no additional benefit at the present time, there are other possible treatments, including radiation and chemotherapy, that may be tried if and when the Lupron no longer adequately suppresses testosterone production. I find it quite possible to continue my daily activities with a minimum of inconvenience. I plan to participate in a clinical trial designed to determine if the administration of dutasteride (Avodart)after 8 months will lessen the need for Lupron. | M | 67 | 5 weeks | 4/30/2009 | 1 | Endometriosis | nausea, depression, cramping, severe hot flashes. others i can't think of. horrible stuff. | I did Lupron for 1 month back in December and am still suffering from occasional hot flashes. The one thing that made me stop after only one shot was the severe depression I experienced about 2-3 weeks into it. I had been diagnosised with PTSD about a year prior to this, but was on the verge of being admitted into the psych ward because of the severe depression and would not recommend this to anyone who has any history of depression at all. It has been a few months but I ruined about 4 bra's due to the excessive sweating from the hot flashes. I would rather take the pain than go through that ever again. | F | 27 | 30 days | 4/29/2009 | 4 | endometriomas | hot flashes, insomnia, decreased pain | After reading different reviews I was terrified to start Lupron as so many people had such negative things to say. Fortunately my experience was positive. My endometriomas shrank significantly and as a result I did not require surgery. My pain also decreased. Staying well hydrated helped to reduce the hot flashes. I would definitely recommend trying Lupon before agreeing to any surgery. | F | 35 | 6 months | 4/25/2009 | 2 | Endometriosis | EXREME, EXTREME Nausea-been to ER 3 times for it (Zoloft did not help me nor did Reglan) Vomiting; Insomnia; restlesness is excessive in legs and throughout; backache | If anyone around the same age is going through what I am, please e-mail me. Support is needed and will be provided to you,too!!! It has been 11-12 days since my laproscopy and lupron shot! I am only 18 years old!ONLY 18. Had to take a year off of University. My life has been turned upside down, man. I hope I find relief soon, but this is kiling me, man. This shot is just so bad. its symptoms I mean. I have had my first period which were PAINFUL as heck! | F | 18 | 12 days | 4/22/2009 | 1 | Severe bleeding and cramping | I started having petit mal seizures and then had a gran mal seizure and was hospitalized. | Do not take it! | F | 30 | 2 months | 4/22/2009 | 1 | Post surgery endometriosis | hot flashes, moodiness, cold sweets, depression | I was given a lupron injection after having a laproscopic surgery to remove the endo. While in surgery it was discovered that I was having a tubal pregnancy and my left fallopian tube was removed. I was told after the procedure that because of the surprise tubal ligation, all the endometriosis was not removed being I had been under anestesia for 3 1/2 hours and they feared greater consequences if they didn't wrap things up. I was given the lupron without my consent (you know you sing the waver saying that the doctor can do what it must to treat you) anyway, I was told the purpose of the injection was clear up the rest of the endo that was not removed. My doctor told me that "she was amazed that I tolerated the pain of both the endo and tubal pregnancy so well, and was surprised I was able to walk." After receiving the first injection which was supposed to be re-administered after 3 months I experienced severe hot flashes, horrible cold night sweats, extreme moodiness and dispression. Even with the side effects I had decided to continue on the path my doctor had chosen for me and receive my second (and last injection) when I arrived at the doctors office for my injection, my doctor had left the practice. That was in August. I have since still experience severe endo pain. I have had a hard time finding a doctor that I trusted. Finally found a nurse practitioner who ran all kinds of test (blood, ultrasound, CT) and decided that the best route for me would be to go back | F | 25 | 3 months | 4/22/2009 | 4 | Endo | I posted on 01/27....pain at the injection site, sore muscles, hot flashes, headaches/migraines, moodiness, loss of libido, some joint pain and soreness, short-term memory loss and inability to focus, depression/anxiety (altho i have a history of both) and dry skin | I posted on 01/27....My side-effects have greatly diminished since I first began Lupron and so has my endo-pain. Before, my hot flashes and mood swings were nearly constant and unbearable and my side-effects were interfering with my professional and personal lives. I have been on Lupron now for about 4 months and have another 3 months to go before re-evaluating my endo/pain. I have *almost* no pain and my hubby and I can be "intimate" again - I'm not so afraid of the pain anymore that i can live my life normally. The only effects I'm still experiencing are ocasional hot flashes, occasional moodiness, headaches and lessened libido (altho it's much better than when I first started the treatment). At this point I am going to follow-thru and hopefully will not need to get surgery!! I would recommend anyone looking to begin this treatment to research it carefully and ask lots of questions. I would also recommend getting a pregnancy test before your first injection - I was not given one (!!!) and spent several months very very concerned....I am hoping Lupron works and lasts, and that when my hubby and I are ready I will be able to have children! | F | 20 | 4.5 months | 4/7/2009 | 4 | Surrogate Mother | I have done 3 shots.... I have had hot flashes, belly ache, loss of appetite.. (not a bad thing).. Some mild mood swings.. | F | 31 | 30 days | 4/5/2009 | 4 | Endometriosis | Hot flashes (mostly at night), very weepy but your doctor can give you medicine if you are this way, as well as medicine for the hot flashes. If you aren't into taking prescription medicine for your moods there is an over the counter medicine from wal*mart or wherever. It is called 5-HTP and it is an erb that curbs appetite and promotes positive mood. | Prepare yourself for the worst and you probably won't be disappointed. :) I wasn't upset with the overall of the drug but I was fairly warned about the symptoms so. | F | 19 | 6 months | 4/5/2009 | 4 | Uterine Fibroids - 3 12 cm diam | Mild, not unpleasant hot flashes. Significant weight gain. | I took the medication for 10 months: 7 one-month doses, and one three-month dose. The hot flashes were very insignificant. The best part was absolutely no migraines and PMS and just feeling "better" overall. I did gain a significant amount of weight (23 pounds) but was reassured by my endocrinologist that this will go away once the medicine is out of my system. I will be getting a TAH in May. | F | 32 | 10 months | 4/3/2009 | 5 | Shrink Uterine Fibroid pre-surgery | mild fatigue, mild headaches | I took the 1x/month shot of lupron for 4 months to shrink my very large fibroid tumor (~15-16cm) in the hopes of having laparoscopic surgery. The lupron shrunk my tumor enough to remove it laparoscopically (yay!). Turns out it was 12 cm after being shrunk! When I first saw this page before I started the lupron I was terrified. I was afraid of hot flashes and (since I have a history of hormone migraines) I was concerned I’d have a 4 month migraine. After the first shot I felt great, but a week later I ended up with a moderate migraine that lasted 5 days. I felt fine for the rest of the month other than being a little more tired than usual. I did have a mild 2-4 day migraine in months 2 and 3, but not the last month. However, after the 1st month, I could feel that it was shrinking my tumor and I had less discomfort and pain from the fibroid. One very important thing that I should mention is that my doctor also had me taking a low dose of progestin (2.5mg of Aygestin) to prevent hot flashes. I only had one incident of night sweats, so it worked. He says this is key and there is no reason for women to suffer by not having add-back therapy. Not to discount any of the experiences on this site, but wanted to let prospective lupron patients know that your experience may not be as bad as others, especially with the aygestin. ASK YOUR DOCTOR about taking progestin. | F | 38 | 4 months | 4/2/2009 | 3 | IVF | No Side Effects Yet | I am only on my forth day of Lupron 10 units a day. I have no side effects yet. Wondering when they will come. | F | 33 | 4 days | 3/31/2009 | 3 | endometriosis | weight gain (15lbs), acne, horrible and unpredictable mood swings, hot flashes that still persist even though i have been off lupron for 3.5 years, extreme nausea (used zofran with some relief), vaginal dryness, hair thinning. | F | 25 | 6 months | 3/25/2009 | 3 | endo/infertility/fibroids/cysts | frequent headaches, swollen hands (rings are tight), WEIGHT GAIN!! of at least 12 pounds, some mood swings | Just got my fourth injection today. Gained another 3 pounds for a total of 12. No period since my first injection in Dec.2008. That's been nice. Bloating/swelling in hands are worse each month. Some ovarian pain couple of days each month. I can't decide if it's all worth it. I feel pretty yucky every day (physically). The verdict is still out! | F | 34 | 4 months | 3/23/2009 | 1 | infertility | Horrible drug. Reproductive endocrinologist prescribed as part of IVF treatment. 3 months AFTER completing 1 IVF cycle with LUPRON: still have not managed to lose the 10 pounds I gained on LUPRON, although have severely restricted calorie intake, (I have never had problems losing weight in the past before LUPRON) still have some tingling in my feet and aching in knees after crouching for a while ( I never experienced this before taking LUPRON ), Condition of my hair is scraggly and poor since LUPRON, Periods for past 3 months since taking LUPRON have been on abnormal 38-day-cycle (I am normally on a 30 day cycle), I had heart palpitations right after I discontinued LUPRON | If you value your health and your sanity, DO NOT TAKE LUPRON Its effects may NEVER wear off, and if they do wear off, it takes MONTHS for it to wear off LUPRON IS NOT NOT NOT FDA-APPROVED FOR INFERTILITY!! | F | 43 | 11 days | 3/22/2009 | 3 | Endometriosis | Very achy all over, swollen joints (cannot even wear wedding ring), acne, mood swings, tiredness, bone and muscle pain, no periods | I had my first injection a month ago, and I am going in for my second this Friday. I really hope all of this eases up, because these symptoms are affecting my ability to work. | F | 25 | 4 months | 3/18/2009 | 4 | endo | slight mood swings, pain from lower back down to knees, FATIGUE | i had taken the 1-month shot for 6 months a few yrs. ago with GREAT results(minimal side effects). but am currently on the 3-month shot and experiencing more problems(coincidence?). i wasn't on add back therapy the first time either. i have had a "cycle" every other week so far and it's terrible. the pain from the side effects is definitely better than the pain from my endometriosis, and i recommend it to anyone in the same situation. | F | 29 | 2.5 months | 3/15/2009 | 3 | Excessive bleeding during periods | I am a 36 year old woman who has excessive bleeding during my periods..Lupron was given to me as a way of decreasing my bleeding, therefore preventing more anemia. I was given my one and only lupron shot in October 08 and to return in 3 months for follow up...have not returned yet. Since then, I have been having severe hot flashes, nausea, headaches, which are more than usual....BUT NO BLEEDING/PERIOD. Yes, it has helped with my period, but definitely has affected my day to day with other symptoms. Lupron not so bad for me, cause I am use to managing symptoms...but I do feel "sick" than normal. | I would highly recommend everyone to read other ratings about Lupron...cause I really made a decision based on my excessive bleeding at the time. Put it like this, if you have never had a hot flash...be prepared, once on Lupron. Now I can be more sensitive to women going through menopause...and I'm only 36. | F | 5 months | 3/12/2009 | 4 | Endometriosis | Hot/cold flashes, face swelling, acne and face blemishes, lower and upper back pain, pain in the shoulders and neck, nausea, irritability, headaches and now migraines, memory loss and short term memory, and mood swings | w/in the 1st mo I had really bad hot flashes, I tried to manage my body temp by wearing tube socks and short sleeve shirts. (sounds funny, but it worked for me esp. thru the winter season. I would have my fan on at my desk which also prevented me from sweating up a storm.) I had cramping the 1st 2 mos which have now subsided (thank god! b/c before then life was miserable. I couldn't do anything w/o being in pain which included walking,sitting, standing, etc. I got so stressed out I was depressed) Glad to hear I wasn't the only one out there dealing w/the same condition. I had my period the 2nd mo and during the 3rd mo I noticed my face swelled up and now I have acne. I got really bad lower back pain and then it moved up to my shoulders and neck. My headaches have gotten worse to the pt where I am getting migraines. Anyone else getting migraines? I have to take a separate med for my migraines so some of my side effects might be a result of this. The Dr. sd my headaches will only get wor | F | 28 | 6 months | 3/9/2009 | 3 | endo | migranes, back pain, shortness of breath, weight gain, mood swings,breast changes,joint pain | F | 15 | 8 months | 3/9/2009 | 4 | endometriosis (severe) with crohn's | Extreme heat flashes, constant one after another, dizziness, nausea, horrible muscle cramping and muscle spasms in back and legs, insomnia, depression, crying spells, anxiety, bone and joint pain, urinary pain, itchiness, fatigue, "flu-like" feeling, some migranes, intolerance to heat and cold, vision changes, memory loss especially the first 3-5 days s/p injection. | I would get faint, extremely nauseated right after injection, I would have to sit in the OB/GYN's office for an extra 30 min. to an hour to ensure I wouldn't pass out while driving home. Has anyone experienced this? | F | 28 | 3 months | 3/4/2009 | 2 | ER/PR positive breast cancer. | Hot flashes, night sweats, painful joints, weight gain | I couldn't take Tamoxiphen after I completed my chemo and radiation. My only option were the Lupron shots every 3 months for 5 years. I am now a year off the shots and I still have lingering issues from the shots. Still have the hot flashes, night sweats, mood swings, and my joints are a wreck. I've gained about 35 lbs in the past 5 years and am having a great deal of trouble taking any weight off. I wish there had been another option for me. | F | 45 | 5 years | 3/3/2009 | 3 | endo | extremely frequent hot flashes (like 1 every 15 to 20 minutes) | It's only been one month and the hot flashes are ridiculous!! But, I guess it's better than the horrible pain I was in from the endo. I just really hope it's all worth it at the end of the 6 month treatment!! Any suggestions for the hot flashes? please email me if so!! I already have a fan on my desk at work, but it just doesn't kick the hot flashes! | F | 31 | 1 months | 3/2/2009 | 1 | Frozen Transfer Fertility cycle | Weight gain of 10 lbs in 10 days, massive bloating, dizzyness, exhaustion, swelling of face, asthma symptoms, extreme mood swings, crying for no reason, depressiom | Used at beginning of frozen cycle, not sure WHY when it's known to cause birth defects, you would think a drug like that would not be used right before an embryo transfer. I pray this works because I can't go through this again | F | 37 | 10 days | 2/25/2009 | 5 | endometriosis | Loss of appetite(which actually is an added benefit!) | F | 40 | 2 weeks | 2/23/2009 | 5 | Severe endometriosis | Maybe a hotflash or two, but nothing serious | I was terrified and put off doing the shot for about 4 months b/c of reading ratings such as the ones on here. I realized that the typical person posting on these is the extreme situation of having a negative experience. My experience has been fantastic. I have lost 8 lbs (much needed) since being on the shot. I have had energy and been able to work out. I hope this will help with our venture in having a baby! | F | 30 | 75 days | 2/21/2009 | 1 | Endometriosis | hot flashes,mood swings,dizziness,nausea,aches & pains in legs,headaches & insomnia | I have only been on it for one week, I had the 1 month injection and can't wait to be done with this drug.I rather have my painful cycle than feel the way I do....AWFUL | F | 32 | 2/21/2009 | 3 | endometriosis | headaches, leg and back aches, some joint pain in knees and hips, hotflashes, mood swings | I have been on Lupron for almost 2 months and I am now starting to get aches and pains. at the beginning of the treatment I just got headaches and some hotflashes and mood swings but now almost 2 months in the aches and pains in my legs and back are killing me (although a pain reliever seems to help). My doctor says it isn't from Lupron but I have never had this problem before and it seems that I am not the only one with this pain while on Lupron. As far as the endometriosis pain that has subsided although a lot of pain went after I had a lap done to remove the larger masses. | F | 26 | 2 months | 2/18/2009 | 5 | Very heavy long bleeding cycles | No issues here | F | 40 | 5 days | 2/17/2009 | 1 | prostate cancer | Inability to perspire with resultant intolereance to heat; bone and joint pain; memory loss. I could not remember names of my friends or pets or even what year it was. | I will never mess with my hormones again, no matter what. | M | 64 | 5 months | 2/16/2009 |
| Key to
ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine. |
