| Rating | Reason | Side Effects | Comments | Sex | Age | Time Taken
and Dosage | | Date Added |
  | | | | F M | | | | |
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| 4 | Fibroids | Joint pain, and slightmemory loss. I get a heavy period a few days after each shot. Semi heavy | I was scared to try this medicine after I read this site, but I am on my 3rd shot ans have very minor symptoms. Joint pain is probably the worst. I have had one hot flash (so far) and memory loss slightly. I thought that I was going to hate this drug, but so far it has not been as bad as a I thought, I get my next ultrasound in about a week so I will know than if the fibroids shrunk. Oh my hair is falling out but not in clumps, just falling out a lot easier than before. I find it everywhere now. | F | 32 | 3 months
1X M | | 8/29/2010
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1 | endometriosis | nausa,vomiting,stomach pain,diaherra,anxiety,insomnia,weight loss | I have done only 1 injection of lupron 11.22 It lasts in your system for 12 weeks. It has been 10 weeks and I just started to eat again. This has been the worst experience ever. I was sick and I mean sick for this whole time. I ended up in er once being totally dehydrated. I could not eat at all. I was either throwing up or had diaherra. I was put on axiety meds to help also. I lost at total of 15lbs. I am not going to take the 2nd dose. | F | 32 | 12 weeks
11.25 1X O | | 8/29/2010
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| 3 | Endometriosis | I had horrible hot flashes and night sweats. Nausea and headaches.I was tired a lot of the time. I felt that my side pain decreased a little bit but around the time of my menstrual cycle each month, I had pain again. I do think it helped. This is my last month on it so Im a bit nervous to see what happens when I am no longer on it. | | F | 20 | 6 months
1X M | | 8/27/2010
| 4 | stage 4 endometriosis | decreased libido, hot flashes, mininal depression | I was TERRIFIED to start the Depo Lupron injections after reading the horror stories posted by patients on internet sites. I began the drug, once a month for 6 months. I can honestly say that I am EXTREMELY sensitive to meds, and, I feel great! I have decreased libido, but, my husband is VERY sensitive to the fact that I'm on a medication that is causing this! Hot flashes DO happen, but, NOTHING unbearable. I am on an antidepressant anyway for generalized anxiety, and, I had to increase my dose VERY slightly. As far as the weight gain --- there has been NONE of that for me. As a matter of fact, I may have lost weight slightly. Please take it from me that this med is NOTHING to be scared of! It is worth the 6 months of treatment! | F | 29 | 3 months
1X M | | 8/26/2010
| 5 | Stage IV endometriosis | None | I was scared to death to get this injection after hearing nothing but horror stories about this drug. I got the three-month injection from my doctor, so there was no turning back with this if I started having bad side effects. I've had no real side effects so far and it's been 12 weeks since my injection. My doctor did put me on add-back therapy with Premarin and I'm sure that's helped reduce any side effects. It has definitely helped my pain from the endo. I wouldn't say it got rid of it 100%, but it's such a drastic improvement. I'm really glad I got the injection. | F | 33 | 3 months
1X O | | 8/24/2010
| 1 | endometriosis | I went crazy ended up in a mental hospital lost my memory Could'nt walk properly had extreme nightsweats/mares I lost my children gained 60 lbs I had no idea what was happening | Please if anyone knows how to get a class action suit going email me at veronicagrayson64@cox.com | F | 45 | 12 months
1X M | | 8/22/2010
| 3 | Fibroids, 13 cm, 5cm, numerous smal | Into 3rd week, period started with more clots than usual, night and day sweats, tingling and numbness in hands and legs, swelling and soreness of feet, some slight pressure in chest. | Third time in 2 1/2 years taking the 3 month injection to stop periods and shrink fibroids. Very little shrinkage of fibroids, stopped period for one month with the first injection, and less bleeding for two months with the second injection. Have had numerous blood transfusions, one time hemoglobin was at 4.2, frightening. Trying to stop period after last transfusion and infusion of iron, so hemoglobin/hematocrit will build over 10.5 in order to have hysterectomy and stop vicious cycle of transfusions, periods, transfusions, periods, etc. | F | 57 | 2.5 years
3 month 1X O | | 8/20/2010
| 4 | Fibroids | Night sweats....in general just hot at night | I have been on Lupron about two weeks. And I haven't had any real negative side effects. Well nothing that I thought was ruining my life as one poster said. But I am keeping an eye out to anything out of the ordinary | F | 33 | 2 weeks
3 month 1X O | | 8/17/2010
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| 3 | Prostate Cancer | fatigue, debilitating hot sweats, hot flashes, loss of concentration, depression, liver dysfunction, weight gain (10 lbs), complete lack of libido, moodiness, lack of enthusiasm, blood sugar swings, sleeplessness | I am very worried about the drug long term effects. It has been over six months since my last injection and the side effects seem to be getting worse rather than better. I will not continue using the drug. My PSA has been greatly reduced but the doctor cannot tell me if it was from a successful, 40 session radiation regimen or the drug. This lack of knowledge of how the drug works and how long it side effects will last (or the magnitude of the effects) leads me to recommend other options. | M | 59 | 9 months
6 month 1X O | | 8/17/2010
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| 3 | Prostate Cancer | Hot Flashes, Cold flashes, weight gain, fatigue, complete loss of libido, Nausea, Depression, Moodiness, Mental degradation (Not Mentally acute) | I had the robotically assisted Laproscopic Prostatechtomy at the end of July 2009, PSA count at 6 weeks out was .55, at 3 months .65, and at 6 months 1.1, so a 8 week course of radiation with Lupron injections was recommended. After 1 month on Lupron the PSA count dropped to Zero, I'm still waiting for the next test, but I cannot stand being on this drug much longer. The moodiness, hot flashes, fatigue, and weight gain are ridiculous. Use this if you must, because it does work, and will extend your life while you work for a cure. But as soon as I can I'm getting of of this stuff. | M | 52 | 5 months
1X O | | 8/12/2010
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| 3 | 11 cm fibroid | | Was initially scared to take Lupron after reading the side effects. In 3rd week of first shot and it hasnt been too bad. I've lost some weight (about 6-7 pounds) from nasuea/vomiting and get night sweats and have some trouble sleeping through the night. But I can tell that the fibroid has shrank some because there isnt as much pressure on my bladder and kidneys. I got my period about 10 days ago and only bled for 2-3 days but have had constant fluid leakage since then. Possibly from the fibroid shrinking. It definatley hasnt been the nightmare I expected it to be but it hasnt been a joyride either. | F | 30 | 3 weeks
3.75 1X M | | 8/4/2010
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| 4 | Stage 4 Endometriosis | I am 25 and I Have had 4 Laperoscopys and with the last one the doctor told me I had Stage 4 endo. He said this was my last opption in getting preggo before i needed to to invetro. I was Realy nervous about taking lupron after reading all of the side effects. On top of being nervouse my Health insurance didnt pay a penny. It was 2500$ a shot here in the US so i Ordered it from Canada for 800$. My doctor told me that the side effects would be the same as menopause. So i was prepaired for hot flashes, night sweats, and Weight Gain. But the Only Side effects I had were the Hot Flashes and Night sweats. I acctually lost 30lbs by just eating a little healthier than normal. I was already a little over weight and didnt want to gain any more. I love Lupron, I love not Having a Period. It got rid of all my Pain and now im just hoping to get preggo!!! | I took 1 Shot every Three months for Six Months | F | 25 | 6 months
11.25 2X O | | 8/2/2010
| 1 | endometriosis | I have been currently diagnosed with endometriosis and was recently given this drug. I freaked out when my stomach went numb as well as my left arm and leg. The doctor couldn't believe the side affect but it has occured. I thought I would try the dose again and see what happens and now I am numb again!!! I will never take this drug again. I would rather have my pain then deal with numbness and tingly sensation in my arm and leg. | | F | 34 | 2 months
30 mg 1X M | | 8/2/2010
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| 1 | Endo | | | F | 44 |
11.25 1X D | | 7/31/2010
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History | 3 | Endometriosis | HEADACHES, night sweats, severe fatigue, mood swings (but only a few severe so far), achy, less of a sex drive than usual. Some nausea too but I think that's just from the endo. The headaches and fatigue are definitely the worst. | I get my 2nd of 6 shots next week. I hope I survive 6 months of this. But it'll be worth it in the end. I'm also taking Aygestin to help with the side effects so I can't imagine what it would be like without it. | F | 27 | 1 months
1X M | | 7/30/2010
| 3 | endometriosis | After having severe pelvic pain and cramping since February of this year, my doctor and I decided to go through with a laparoscopy which I had about 8 days ago, my doctor was able to get most of the endometriosis but not all of it so she suggested Lupron. My aunt is an OB/GYN and suggested that surgery + Lupron is the best way to go. I have an appt tomorrow to start, I have read so much about all the side effects and possible problems with it. Out of everything that I have read nothing says when you start feeling the side effect i.e. 1st day or 1 week later? anybody have any input? I will also post again and let people know how my experience goes. My ultimate goal in this whole process is obvious pain relief but also hopefully I will be able to have kids since I am only 24 yrs old. | | F | 24 | 6 months
1X M | | 7/28/2010
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| 3 | Egg Donor | I am experiencing spotting and some minor menstrual-like cramps and bloating. I'm not sure if the cramps/spotting are due to Lupron, or to Reclipsen, which is a birth control pill I also have to take. I have noticed spotting consistently for the past 3 months with Reclipsen but the Lupron did seem to make the spotting heavier, almost more like a light period.
I do not get migraines normally so I haven't experienced anything like that on this medication.
The side effects are a little uncomfortable but I'm still able to go about my day as normal. So far it seems like a tolerable level of mild discomfort to help someone have a baby.
I have not noticed anything major and I expected the bloating, which is more of a "feeling" of bloating than anything physically visible. I have a healthy diet and exercise routine generally. I also eat a low sodium diet which I think helps reduce the bloating. | I am an otherwise healthy, fertile egg donor taking Lupron to stimulate egg production and coordinate my cycle with a surrogate mother. I rated it a "3" because I'm not taking it for my own medical/fertility reasons, but to help another couple. | F | 28 | 5 days
10 Units 1X D | | 7/27/2010
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| 4 | Fibroid | None | I took my first shot a week ago, I haven't had any side effects at all, will update in 4 weeks more. I'm taking the dosage to try to shrunk a large fibroid for surgery. | F | 29 | 7 days
11.25 X 3 1X M | | 7/18/2010
| 1 | Severe Endometriosis | Depression, dryness, severe mood swings, acne, weight gain, insomnia, nervousness, anxiety, loss of sexual interest, dry mouth, hot flashes | I had a laparoscopy last year, and they found that I'm covered in endo. I had to diagnose myself with endo, after YEARS of complaining to doctors. They didn't remove any of it, except what they thought was causing pain with intercourse, and recommended that I take Lupron for a year, and then have a full hysterectomy. The first month shot was crazy, I had a hard time performing at work (still do), but I agreed to two more 3 month shots after that. I was hoping to stop my period until we could decide to have kids or not. I am extremely active, and do crossfit workouts 4 times a week, so I shouldn't be looking like I'm pregnant. My stomach is getting bigger and bigger! I've never been overweight before in my life. I'm never going to take this shot again, I don't care how bad my periods are. Between the first one month shot and the second 3 month shot, my doctor's assistant didn't order the shots on time, and I had my period for 2 months straight! Also a huge piece of light pink flesh came out of me, the size of three fingers together. I called my doctor, and they just giggled, and suggested that, "all kinds of crazy things come out of vaginas". I've been to several doctors, and they all suggest this drug. I feel like the doctors just don't really care about endo, and this is a catch-all treatment. Why would you want to make your brain believe you are in menopause? There is something seriously wrong with this hard core solution. | F | 35 | 7 months
3month sho 1X O | | 7/15/2010
| 1 | endometriosis | nausa,vomiting,diarrhea,chills,stomach cramps,anxiety, not hungry at all. | I have been on this medication for 3 weeks now and it has been an horrible experience. I have been so sick.At this moment I'm making myself eat. I am supposed to get another shot in 3 months and I will not be getting it. | F | 32 | 3 weeks
11.25 1X O | | 7/14/2010
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| 3 | Fibroids | Forgetfullness, loss of appetite, tired, daily spotting, sleeplessness, weight gain (10 lbs), emotional fits, a quick period every 3 weeks, mood swings | I felt the need to comment on this drug. I took this for 3 months, and unfortunately did not have any shrinkage of my fibroids. I will be getting a myomectomy in a little bit. The most profound side effect was a very intense period about 2 weeks after I had my initial injection. I thought I was going to die... Otherwise, most of my physical symptoms weren't bad. My emotional state was not good, mood swings certainly present, and marked emotional times happened every few weeks. Also, I noticed my general heart rate/pulse went down. Just a strange drug. | F | 30 | 3 months
3 month 1X M | | 7/12/2010
| 4 | endometriosis | nothing for now | i had my first shot a week ago and i have been doing fine, side effect might be to small to notice. i ll keep you updated in 4 weeks. | F | 27 | 6 months
11mg 1X O | | 7/11/2010
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| 5 | Endometriosis | I was very emotional and angry for the first 1-3 weeks. I was menstruating when I received my first shot and then had another, very persistent period with heavy flow about 1.5 weeks later that lasted for about 8-10 days. I have gained a few pounds, but I think that is a result of emotional eating the first month. | I was terrified to take this drug after reading what other people said about their experiences with it. I actually delayed taking it for two months as I hashed it out with my OBGYN. In the end, I trusted her that the side effects are minimal and that the benefits are great. As my hormones fluctuated the first few weeks I did have an additional period and very emotional mood swings (but this was expected). By the end of the first month I can say that I feel great! I just received my second shot. I am pain free, period free and am so glad that I decided to go with Lupron. And no...I don't work for the drug company, I'm a teacher. Please contact me if you want to know more about my experience. | F | 32 | 2 months
3.75mg 1X M | | 6/23/2010
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| 5 | severe Endrometriosis | 1st month: headaches, drowsiness, fatigue. 2nd-4th month: weight gain, moodiness, spotting, short period of heavy bleeding | After having a Lap, still had Endro, so my Dr recommended Lupron. Like everyone else, I read the horror stories about the drug, and was terrified to take it. I knew it was my only chance at being able to have kids one day, so I agreed to take it for 6 months. I have had a 1 month injection and a 3 month injection (which made it nice that I didn't have to go every month for an injection) I've read alot that after a month, girls have had bad side effects and quit Lupron. Well, the 1st month is when your body is getting used to it, and it's probably the worst month. I haven't had any hot flashes or night sweats. The biggest side effect has been moodiness. After taking it, I got depressed and was very edgy. So my Dr put me on Wellbutron, an anti-depressant. I didn't like the thought of being on it, but it's made such a difference, and now I've never been happier! I had very severe cramping and pains for many years, and I've had absolutely NO pain since I've been on this drug, for the exception of one cramp about the 2nd month in. There was a month that I didn't have much sex drive, and dryness has been an issue. I've had light spotting, and my 3rd (and now my 4th) month into it, I had a week of heavy bleeding. I found out from my Dr that "breakthrough bleeding" can be a side effect from this drug. I did gain 20 pounds. I hate it, but most will go away once I'm off the drug. Not everyone has the same side effects, but overall, I'm extremely happy that I went through with | F | 23 | 4 months
1X AN | | 6/22/2010
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| 1 | Supposed Endometriosis | Too many to describe | I can write a book on the HORRIBLE things this did to my body and almost 5 years later, I'm still suffering! Any chemical that alters the function of your pituitary gland (the master gland that controls everything, can't be good!!! | F | 44 | 6 months
1X M | | 6/22/2010
| 5 | Endometriosis | Hot flashes, night sweats!!!! | Lupron saved my life! I was diagnosed last Sept'09 with Endometriosis. My cyst was 14cm in diameter! After surgery we tried to get pregnant w/out success. My periods were awful, I was in so much pain that I was doubled over. The pain was so bad I cried myself to sleep. After months of trying and having severe pain during my period I went back to my doctor to find out the endometriosis was back, this time it was 11cm in diameter. My doctor suggested Lupron, I had no idea what the drug was all about or how it would affect me. I was willing to try anything at this point. I've been on Lupron for 3 months now and have experienced a huge difference. I feel like I have my life back. The pain is GONE. I have hot flashes all the time, which is annoying but it's worth it. The night sweats are constant, I've also noticed a big difference in my sleep patterns. I would normally wake up once or twice before the Lupron. Now, I'm waiting up 5-6 times b/c I'm hot, thirsty or have to use the bathroom. I'm having surgery next month to removed the endometrioma. After surgery we're going right into IVF. I would strongly recommend Lupron to anyone with Endometriosis. It's a life saver!!! Good luck to all! | F | 34 | 3 months
3.75mg 1X M | | 6/17/2010
| 3 | Endo/infertility | hot flashes, increased appetite, mood swings | I cannot say if it worked or not...I will have my last injection July 1 and then can start trying to get pregnant again. If I get pregnant, obviously it worked, if not, then I am not sure. | F | 25 | 3 months
1X M | | 6/15/2010
| 4 | Endometriosis | depression, night sweats, fatigue, irritability, anger | Don't believe the reports! Yes, the drug will put you into "menopause," with all that comes along with that, but that's how the drug is designed! And, above all, it actually WORKS!! I had severe endo pain every month with inexplicable pain during the month also. I read the nay-sayers and was terrified to take the injection. I am so glad I did. If my doctor would give it to me, I would stay on it forever. You will definitely want to talk with your doctor if you start to feel really moody or depressed, because you might need another drug like me (Zoloft). However, I'd rather be on Zoloft and NOT IN PAIN than just IN PAIN! | F | 27 | 6 months
3.75 1X M | | 6/13/2010
| 1 | to try and shrink fibroids | my side effects were dizziness, hot flashes, violent mood swings, joint pain | my doctor told me i needed it because i had fibroids which was causing anemia. she never told me about side effects, only that it would stop my period. when i took 1st shot i bled for 1 month and a half. i told her i didn't want another one and she said i had to or she wouldn't do surgery. my surgery is scheduled for this tuesday and after taking this drug i still have to be cut, because it didn't shrink fibroids | F | 34 | 3 months
3.75 1X M | | 6/12/2010
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| 5 | Endometriosis | hot flashes, dizziness, weight gain, mood swings, anxiety | I just took the final injection to treat my endometriosis. The injections often made me extremely hot and moody. The pain, however, is gone. I am very happy with the outcome of the treatment, but I HATE the side effects that come with this drug. | F | 17 | 3 months
1X M | | 6/6/2010
| 5 | Endometriosis | increased appetite, minimal weight gain (2 lbs), extremely infrequent hot flashes | I read other peoples comments about this drug before beginning treatment, and it made me very skeptical. I'm very happy that I went through with receiving the injections, however. I have gone four months without having any discomfort related to my endometriosis. My symptoms are also VERY minimal. The first few weeks were hard, just with adjusting to the new med. I had frequent headaches and an increase in stomach cramping. But after that, I've never felt better. I have a hot flash every once in a while. In the last four months I've probably only had a handful of them. My appetite had increased, and I've gained a few pounds, but I've been able to control it with regular exercise, so it isn't concerning to me. Overall I've responded extremely well, and I'm so glad that I took the chance on this medication. I know there are so many negative comments about Lupron, but every individual person is going to respond differently. My advice is to at least try it. I decided to give it a try even when I was worried about all the potential complications, and I'm so happy that I did. | F | 23 | 4 months
3.75 mg 1X M | | 5/30/2010
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| 3 | fibroids | painful joint pain, vaginal discharge continuously (faint bleeding to watery), 2nd month severe cramping | My hemoglobin was so low I had to be hospitalized and transfusions. The lupron by the second month had slowed my periods down quite a bit. I think my fibroids have shrunk but there are side effects. My joints ache all day long, especially my feet, ankles, hands and fingers. I wake up almost crying from the joint pain. I have not had hot flashes yet. I have mood swings but cant say if its from the drug. | M | 46 | 2 months
monthly 1X M | | 5/25/2010
| 4 | Endometriosis | I have had terrible hot flashes, and more recently my endo symptoms have come back. | Well without boing you with TMI. I have had 4 laps (2005,2006, 2007,2008) Following my last one I was put on Lupron I have taken it continuously (except for 2 months) since then. I get bone density scans every 6 months. It has been a life saver. I am hoping when I have my next lap the docs will say I have the green light to have babies...Don't rule it out. Taking Lupron gave me an extra year of no surgery...The side effects are mild compared to the pain!! | F | 22 | 2.5 years
3.25mg 1X M | | 5/22/2010
| 1 | shrink fibroids for a hysterectomy | The sample shot made me bleed continuously for 4 weeks until I got the 3month depot. That shot stopped my flow but made my emotions go crazy. By the 3rd week I was angry all the time, and was suffering from violent hot flashes that were much worse than the sample stuff. Depression set in by the 2nd month followed by a tapering off of the emotional stuff but the hair loss in the third month? OMG! Handfuls of hair after each washing. Went from wearing my hair in 4 individual ponytails to just one because there wasn't enough hair for four anymore. I'm not bald but my hair is dramatically thinner. Worst of all, the main fibroid they were trying to shrink didn't reduce at all after 4 months on it. I refused to take the second shot the GYN wanted to give me. I'll take an abdominal cut rather than go through that for 3 more months hoping for laproscopic surgery. One more thing: High Blood Pressure! I've never had a high reading in my life. After I asked the gyn about the side eff | So the GYN put me on the pill to bring my estrogen levels up. I asked her how long til my own kick back in, she said 2-3 months. Wow. The withdrawal from this stuff takes a long time huh? | F | 45 | 4 months
3mo Depot+ 1X O | | 5/20/2010
| 1 | Endometriosis | Severe anxiety attacks, mood swings. | I was supposed to take 6 injections over 6 months. Thank goodness my symptoms appeared within the first two weeks because I cancelled my prescription. Although the pain went away for a couple of weeks, it came back with a vengeance! I was having severe anxiety attacks and mood swings. 2 months after getting off of the Lupron, I had a miscarriage and will be having my uterus and ovaries removed. I wish I'd had this done from the start... AVOID LURPON! | F | 37 | 1 months
1X M | | 5/19/2010
| 4 | Severe Endometriosis | minimal hot flashes, night sweats, loss of sex drive | I had my second of three shots on May 12, 2010 and so far I have been pain free. I would take the side effects that I am having over the pain I experienced for years. I have not gained a pound. I try to eat healthy, and exercise at least 3-4 times per week i.e. brisk walking for at least half hour using Leslie Sansone's walk-at-home program. I must say that I am happy with Lupron and what it has done for me. I guess everyone's body is different but some side effects can be controlled e.g. weight gain. I must mention that I have somewhat lost my sex drive but my husband understands and is very supportive. The priority right now is knowing that I am feeling much better. This too shall pass. | F | 37 | 2 months
1X M | | 5/18/2010
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| 4 | endo | | | F | 47 |
unknown 1X D | | 5/16/2010
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History | 2 | endometriosis | Severe mood swings, hot flashes, hair loss, weight gain, depression | Happy the pain is gone but I turned into a different person with the mood swings and depression. I am a very out going and happy person prior to the shot. The medicine effected my job I was on short term because of the mood swings and crying outbursts from no where. I can wait to be off this drug!!
However this drug is like all others and it effects everyone differently and no everyone has effects so don't be scared to try it. I know someone who had no side effects. | F | 29 | 5 months
3.75 1X M | | 5/14/2010
| 3 | Endometriosis/Cysts | weight loss, depression, hot flashes, dizziness, night sweats, COMPLETE LOSS OF SEX DRIVE | The first month, this drug seems like a miracle to me, I wasn't in pain for a whole month!! I usually had two or more episodes of cysts bursting and HORRIBLE pelvic pains that would last for weeks- to where I would have to take vicodin every time I ate because just the movement of my bowels would start heavy cramps.
I was happy with not being in pain, and barely had any side effects for a month... now I have a lot, and they seem to be getting worse. I have ZERO sex drive, even kissing my boyfriend of a year is a turn off. I don't want him to hold me, or touch me, and I am just grossed out by the idea of sex. I used to LOVVVEEE making love, so it's very depressing. I have been crying to him about it constantly.
I also wake up in sweats, and either feel FREEZING COLD or have a hot flash every day. I am dizzy, and I have very little appetite. I have also LOST 13 lbs, which has brought me down to 96 lbs!!! I have always had mild depression, but it's been RIDICULOUS lately how down I am.
I am pretty sure I am going to reject taking this shot again. I'd rather have a laproscopic surgery or something, I can't take what this is doing to my life. It works GREAT for not having pain, but I personally can't deal with the side effects. If you think you can, then you will be happy with how it helps your pain. I do appreciate not being in any pain anymore... I'm just too young not to have a sex drive and I fear it's ruining my relationship. | F | 21 | 2 months
1X D | | 5/13/2010
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| 4 | Endometriosis | Dizziness, headaches, lost of appetite. | I have Endo and my Dr. Recommended Lupron Depot 3.75 mg once a month for 6 months. When I started reading the side effects I was scared to death, to be honest and I was going to refuse the shot. Than I decided to try it and I had my first IM dose on Monday 5/3/10 and had my period the exact same day. First I had the worst cramps ever during my period in my first 3 days after the shot that usually last 7 to 8 days plus another 5 days spotting (almost have of the month) and after the day 4 my bleeding was reduced considerably (almost to none), I have no more cramps, side effects has been minimal just a little dizzy and nauseated and a daily light headache that goes away with Tylenol, also I have experienced some appetite lost. I have to admit that I feel a lot better in those few days and I am very positive now about this medication. I hope it continues working for me and for those on it :). Good luck!! | F | 32 | 6 days
3.75 1X M | | 5/7/2010
| 5 | endometriosis | | I was diagnosed with Endo when I was 16, and underwent 2 laps for Endo removal, cysts and adhesions...I was able to conceive and now have an 8 year old. After the past year of suffering, hemmorrhaging and dealing with Depo Provera side affects, it was suggested to me that I try Lupron. After reading this site in the few weeks leading up to my first injection, I was scared to death that I would suddenly be thrown into menopause with devastating side affects...I've been on it now for a month, to get my next shot tomorrow, and I have not had one single problem, if there has been a side affect, it's been too minimal to notice. I feel 110% better! No more cramping, my mood is actually back to normal, happy and positive and the spotting/bleeding I was enduring for 7 weeks straight stopped within 2 days of the shot. I urge those considering to start Lupron to read and read again, however...don't be terrified of itand how it is affecting others, you may be among the lucky ones that have minimal/no side affects, and you might be back to your old self as I am. :) | F | 34 | 1 months
1X M | | 4/18/2010
| 1 | Prostate Cancer | Mood swings, suicidal thoughts, joint pain, poor memory, poor concentration, insomnia, loss of libido, weight gain, increased blood pressure, lethargy | I was diagnosed with stage 1 prostate cancer about a year ago. Lupron was used to reduce the size of my prostate so that I could undergo external radiation, followed by implanting seeds. Due to the size of my prostate, if Lupron was not used, I would have been required to undergo three more weeks of external radiation. In retrospect, this was a bad judgment call on the part of my urologist and radiation oncologist. I already had high, and difficult to control hypertension. The Lupron is known to cause weight gain and insomnia. Both of these are factors in hypertension and increase the risk of stroke. I don't think the small improvement in cancer treatment was offset by the danger in increasing my blood pressure. I received two three-month injections of Lupron. The last one was five months ago. I continue to have insomnia and joint pain. Because I am sleep deprived I am unable to lose weight and thus my blood pressure remains very high. Sleep medications have been doing a poor job improving my sleep. Had I been better educated about this drug and the inherent risks I would have likely refused to take it would have instead elected to have only external radiation therapy. Lupron is a horrible drug and I will never take it again. I would strongly recommend that anyone considering treatment with Lupron explore alternatives. | M | 60 | 6 months
22.5 1X O | | 4/17/2010
| 4 | Infertility Treatment/IUI | None | I was nervous about taking Lupron, but it's been fine. | F | 43 | 2 weeks
10 then 5 1X D | | 4/11/2010
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| 3 | stage 4 endometriosis and pre-IVF | headaches 1st month, hot flashes and night sweats. insomnia, gained about 10 lbs in 1st month that has maintained the same throughout. worked great to take away pain and love haveing no period!!! some spotting first 2 weeks. muscle and bone aches on and off. but most disturbing was blurred vision and double vision towards end of 2nd shot just before 3rd. this caused nausia and motion sickness. not sure if starting estrogen at beginning of 2nd shot caused this! definately exhaustion and memory loss/gaps too! mood swings occasionaly. /loss of appetite and dehydration | for the pain of endometriosis this is great! i am 33 years old and i have stage 4 endometriosis. i had surgery in january 2010 in which my tubes were removed. i had my 1st lupron injection on1/18/10, 2nd on 2/18/10, and 3rd on 3/22/10. i started estrogen on 2/23/10. insomnia started after 2nd shot and blured/double vision just before 3rd shot. i am going on 25 days of vision disturbance! i have even seen and ENT doc, optomologis, and neurologist. they have tested me for EVERYTHING, and are finally coming to the conclusion that it may be these meds! i am getting ready for IVF, so worth it...i hope so! But so disturbing that doctors are so ready to give these meds and so reluctant to admit the good with the bad! i hope this passes....anyone else have these problems? if so....did it ever go away? | F | 33 | 3 months
1X M | | 4/8/2010
| 3 | Edenomyosis with polysitic ovaries | Hi i am diagnosed with edenomyosis and polysistic ovaries. My dr. had given me 2 options as my bleeding was heavy with hugh clots and it last for months and months .. now its been two years that i am having this edenomyosis and polisystic ovaries.. i wanted to have children as the 2 option that dr gave is to take a lupron injection or to have a hystronomy.After the 1st injection for 1 week i couldnt get out of bed due to heavy bleeding and cramps on my lower abdomen. Now my 6 months is over with 2 dose of lupron injection for 3 months each and i am subscribe with calcium and folic acid tablets. My dr said i will get my period and can try for a baby but the thing is that the bleeding sometimes is very mild and sometime a but like spotting. And today i had spotting and then a gain with hugh clots .. whats going on?? I cant even try for a baby and I dont want to get worse like before.. can anyone help?? | | F | 30 | 3 months
1 1X M | | 4/1/2010
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| 4 | Endometriosis | Hot Flashes, body aches, mood swings, headache | I took Lupron 13 years ago. I had severe endo and was only in my mid 20's then and wanted more children. My endo started after I had my first child and I wanted to wait about hysterectomy so I chose Lupron. My hotflashes almost started immediately but my periods were so much better. I had been having to go to bed because I cramped so bad before Lupron and even the week after my period I would be doubled over with pain in my rectum that would put me on my knees in excrutiating pain that felt like a knife stabbing me. But now I think I see side effects from it but my endo hasn't gotten as bad as it was before I ever took it! I have just started having terrible periods again! It's like the Lupron worked on me for years and that is amazing. However, I have had joint pain that goes to the bone and I am so restless at night. My hair has thinned so much, but I can't say it is the Lupron that caused this but I feel like it did. If I would have known it would cause me this much joint pain and muscle aching I wouldn't have taken it. Although, at the time I started it I was desperate for pain relief so at the time it gave me my life back. It's just weighing out your options. I never had any more children after the one because I kept having miscarriages and not really sure why. I only took it for 4 mo and stopped because the hot flashes were so intense. But at the age of 41 and starting to have pms and heavy heavy painful periods again I think it's time for a hysterectomy. | F | 41 | 4 months
30mg 1X M | | 3/26/2010
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| 3 | Fibroids | None | I had serious reservations about getting the Lupron shot after reading a number of the patient comments ... I can say that for myself I have not had a single side effect. I even thought the medication was not working at all because I still bleed heavily after receiving the shot.
I have not had any pain at the site of injection, no hot flashes that were horrible, no moodiness ... nothing. I can say that for the first time since February 15th I have been able to step outside of my home and enjoy a weekend out with friends without having to carry a bag with extra clothing.
It is still early in my teartment so we'll see how this works, but as of today ... nothing. | F | 43 |
22.5 mg 1X D | | 3/22/2010
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History | 1 | endometriosis | severe hot flashes, bone and joint pain and constant hip pain, "memory fog", weight gain, exhaustion, chronic migraines, trouble sleeping, depression | I wish I had listened to the other reviewers here. Lupron ruined my life. I went through all those side effects month after month thinking "maybe NEXT month it will help... maybe NEXT month..." but of course NOTHING. I am left with worse endo pain then ever, can hardly walk because of the lasting pain - my last shot was 3 months ago and I STILL don't feel normal - and I gained 40 lbs that I cannot seem to shed no matter what I do. Stay away from this drug!! | F | 27 | 6 months
unknown 1X M | | 3/20/2010
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| 2 | severe stage 4 endomtriosis | cramps, spotting, lower back pain, loss of appetite, migraines, night sweats, acne, bowel issues. | I was forced to start taking Lupron again last month. After 8 years of successfully controlling endometriosis with Synarol, my insurance decided to stop covering it. After two months I was already having severe pain and the beginning of more growths. I tried Lupron years ago and was unhappy for all the reasons you see listed - plus, it didn't control my endomitriosis pain completely. I am still appealing the decision, but luckily have new health insurance beginning May 1. I am on the every three month dose. | F | 39 | 3 weeks
3X O | | 3/4/2010
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| 3 | To treat endometriosis post surgery | I'm coming up on my 4th month/shot of Lupron. I've been spotting with heavier episodes of bleeding since about the 3rd week. Hot flashes, extreme night sweats, mood swings, congestion, headaches, overall feelings of achiness/generally just feeling bad. Slight blurred vision moments, extremely dry eyes. Starting to have weight gain. | I had 5 ovarian cysts removed on 12/1/09, one being the size of a grapefruit. I also have a few fibroids remaining. My dr. recommended Lupron right after to ensure that no cysts grow back. At first, I lost weight. Now I'm gaining weight and never seem to be full or control my appetite. I'm up about 5-7 pounds from month 1. I work out, but find it hard to muster up the energy. I've also been bleeding with terrible cramps since about the 3rd week of treatment. Most of the time it is spotting, then it flares up. It especially flares up after working out including bad cramps. My dr. gave me Ponstel for cramps. I have to keep working out to manage this weight gain and bloating, but it's frustrating because of the bleeding/cramps. I'm nervous about my upcoming shot in about 2 weeks; it's a 3 month dose instead of the monthly shots. If my hair starts falling out, I might quit this treatment. This drug is also costing me a fortune. I hope it works and controls future periods/fibroids/cysts. I'm 30 and haven't had children yet....I would love to have children some day! Has anybody else been bleeding constantly for 3 months? (I'm also taking the ad-back therapy daily pill which helps limit the extremity of side-effects, although doesn't take them away). | F | 30 |
1xmonth 1X D | | 2/27/2010
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History | 3 | Endometriosis | fatigue, insomnia, mood swings, severe muscle/joint aches, migranes (only a few), blurred vision (comes & goes), high blood pressure, hot flashes, night sweats. | I'm in my 3rd month of treatment. While the shot has taken away all of my pain and bleeding, it has left me with more side effects than I care to have. After suggestion from my doctor to try the ad-back therapy, I decided to try it...what could it hurt. But the side affects from the ad-back were actually worse than that of the side affects of the Lupron. Worse hot flashes, extreme mood swings, and horrible insomnia. After 1 week I stopped the ad-back and I am patiently waiting for the next 3 months to quickly pass and hope it has taken care of the issue. Next step for me is surgery. I would only recommend Lupron as a last ditched effort to save your Uterus and Ovaries. Try everything else first. If I had to do it all over, I would still suffer through these side affects rather than have the pain/bleeding or a radical hysterectomy at 35. | F | 35 | 6 months
3.75 1X W | | 2/22/2010
| 3 | endometriosis | Bone and joint pain, headaches, mild memory/concentration problems, slight mood changes | I was diagnosed with endometriosis in June 2009 and started continueously using birth control (nuva ring) for 7 months to help minimize my symptoms. I noticed my symptoms never got any better, in fact they started to get worse. In December 2009 I finally saw my doctor and we discussed other options. My options were Lupron or surgery. After hearing about Lupron, I opted to try the surgery. I had my surgery in January 2010 and my doctor said that he was surprised the amount and severity of my endometriosis and scar tissue he found. After that he suggested that I start Lupron as well to help eliminate anything that he missed during surgery. I have only had one shot so far and it really hasn't been as bad as I thought. I have had mild symptoms and notice that even though the severity of my cramping is the same, the frequency has lessened. My doctor put me on an "add back" therapy which I believe has helped with the side effects of the shots. | F | 23 | 6 months
1X M | | 2/19/2010
| 3 | Stage 4 Endo | Extreme joint pain (only 3-5 days after each shot), hot flashes, night sweats, chills, loss of appetite, extreme hair loss, memory loss, fatigue, urinary and bowel movement issues, and moodiness | I had surgery 8 months ago and found out that not only did I have Endo, but it was stage 4. I just had my 4th shot and I am not sure if it is all worth it. I have been having major issues with my bladder and the Dr. thinks the endo may still have grown and is effecting it. I have been able to deal with most of these side effects with a positive attitude and taking it in stride until today when I washed my hair and chunks came out. After blowdrying it, there are spots that are so thin it is almost bald. I am hoping and praying this comes back. I know it sounds vain, but we deal with so much pain and side effects on the inside, I hate that now it is showing on the outside too! | F | 33 | 4 months
1X M | | 2/19/2010
| 5 | endometriosis | the only side effect that I have had from the Lupron shot is hot flashes, night sweats, and some vagnial smelling. | I was really scared about take Lupron from seeing the side effects that people have had especially on this site. I started my add back medication right away and at first I was a little crabby, and had spotting all the time I talked to my doctor though and she uped my add back meds and I was fine. | F | 28 | 6 months
1X M | | 2/16/2010
| 4 | Endometriosis | Soreness the first week. | I wanted to submit a review after I finished taking Lupron because, when I first took the drug, the reviews terrified me. I was convinced I was going to end up depressed, gain 50 lbs, and be unable to walk. Well, I just finished taking it (two times of once every three months) and I had absolutely no problems. Of course, I was on Depo Provera for a long time before that, so my estrogen was already pretty low. Still, not everyone will have problems, so hopefully someone who just started the drug will see this and be given some perspective. In terms of pain, btw, it was okay--Depo helped with the pain more. | F | 22 | 6 months
1X O | | 2/16/2010
| 4 | Endometriosis | Horrible cramping and spotting so far for the last 3 weeks since my first shot. I feel that my body temperature is a little bit warmer. My fingers will get bright red and hot while the rest of my body is fine- kind of weird. I was prescribed add-back which I'm sure has helped. Other than that, I've been pleased. | The cramping and spotting is the most annoying, but knowing that the cramping will get better from the Lupron reminds me why I'm taking it. These posts are scarey and I debated for a long time about taking the shot. I should have just done it right away. It's important to realize that everyone is different. For the most part, I feel exactly the same. | F | 26 | 3 weeks
not sure 1X M | | 2/11/2010
| 1 | Ivf suppression med | Severe migraines, ovulated through the drug, corpus luteum cyst | Within a couple days I had one of the worst migraines of my life. These lasted a couple of days and then subsided. At my suppression check, it was discovered I had ovulated while on lupron and had a large corpus luteum cyst. My doc then increased my dose fom 5 to 20 units which had the end result of oversuppressing me. My cl cyst was quite painful. When the cyst burst, I can honestly say it was the worst pain I've experienced outside of childbirth. For my next IVF cycle my RE switched me to a different protocol that did not involve lupron. | F | 30 | 3 weeks
5-20 units 1X D | | 2/9/2010
| 3 | Endo | Headaches, MILD confusion/memory loss, night sweats, mild hot flashes, mild sadness, mild acne & weight gain. | It's only been 1 week but so far the side effects have been mild w/ the exception of headaches. They're a daily occurrence, get more intense each day. I'm on once/mo. for 6 mos., take 5 mg progestin daily as "add back". Stage 3 endo, diagnosed in Dec. Was on the pill for about 18 mos w/out improvement so doc suggested lupron. I'd actually not be too bothered by most side effects, but the weight gain, acne & mood swings. I struggle w/ my mood as it is, & w/ weight so I'm not impressed w/ gaining about 3 lbs in a week. The weirdest thing is the false 'hunger' I have. It's quite bizarre; I'm sorta hungry & full at the same time. I'll eat & be full but 30 min later get almost like hunger pangs; yet I'm STILL FULL! It's nuts! Also noticed I'm actually eating a lil' less cuz I get nauseated bout 1/2way into a meal probably 1/2 the time I eat. Haven't had TOO many hot flashes; been pretty tolerable but I've gotten night sweats & woke up SOAKED in the a.m. past couple days. Feel overall kinda tired & forgot what I was doing mid-task a couple times. Still in the stage where estrogen is actually "surging" before it drops so I guess side effects will probably intensify the next few wks. I feel awful for those who had such a negative experience but for ME so far I've noticed my pain's already reduced. Started shot 1st day of my period & it only lasted 1.5 days vs. a "normal" week-long cycle. I'm keeping my fingers crossed that ben | F | 29 | 1 weeks
1X M | | 2/5/2010
| 1 | endomitriosis | I was givin lupron to help early endo. It destroyed my life. I had horrible hot flashes, extreem bone pain, muscle spasums and achs, terrible mood swings and messed up my thinking. Had short term memory loss. I still continued to have pain threw the shot, it was not good for me and i only ahd the shot once. I was on my peroid for three weeks straight then didnt have it for three months | | F | 17 | 1 times
1X O | | 2/3/2010
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| 3 | Fibroids | Extreme Hot Flashes; High Blood Pressure | Though the bleedng has stopped after the first shot; my blood pressure has shot up to 160/90. Has anyone else had this happen? Make sure you check your blood pressure while on this drug. | F | 53 | 2 months
| | 1/27/2010
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| 1 | Hypothyroidism and PCOS | Mood swings- super emotional, memory loss/confusion, spacey, | Treatment done in June and July 2009. It wreaked havoc on my body I haven't been the same since. I had gotten to the point where I was finally losing weight and I was feeling okay. I think I just needed to be taken off of birth control. My body doesn't like pills with hormones. Instead, I got some doses of lupron. AHH!!! Anyone know anything about lawsuits? | F | 24 | 2 months
| | 1/25/2010
| 5 | Fibroids and endometriosis | HOT hot flashes, vaginal dryness, dry skin and eyes, occasional night sweats. | WELL worth the inconvenience and side effects, Lupron really did the trick in shrinking all my fibroids (I had about five large ones) and shutting down the endo. I had surgery first, followed by six months of Lupron Depot injections. I never had a recurrence of either the endometriosis or the fibroids. I would recommend Lupron to anyone with severe bleeding problems and for whom hysterectomy was the first solution given by a doctor. The first three doctors I saw wanted to do an immediate hysterectomy and never mentioned Lupron. The fourth doctor suggested surgery followed by Lupron -- we would have done it the other way around except I was bleeding so much that I was on the edge of not being an acceptable candidate for surgery because my hemocrit levels were so low.
I, too, have chemotherapy experience from a late-stage childhood cancer -- 11 months of MOPP chemo, which was nasty indeed. The Lupron wasn't even close to chemo, not in the same universe. And the Lupron side effects are temporary, unlike chemo and radiation side effects that I'm still dealing with 30 years later. If you believe as I do that keeping your uterus intact is important (talk to older women who have had hysterectomies and many years to live with the aftereffects -- younger women won't experience as many problems), then I truly can't recommend Lupron enough. | F | 47 | 6 months
| | 1/22/2010
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| 3 | Fibroids | I became very emotional. Cry at a drop of a hat; have become very depressed or angry at times. loss of short term memory, extreme fatigue, joint pain. Night sweats and hot flashes; hair loss | This drug is, in my opinion, a last resort type of drug. If I didn't need the benefits of this drug, I would NOT EVER take this drug again. I'm crossing my fingers that it has done what my doctor stated it would do...please because I don't want to do this again | F | 31 | 3 months
| | 1/22/2010
| 4 | Endo/ Polycystic ovarian syndrome | Hot flashes, cramps, short term memory loss, dryness, insomnia, moodiness, lower back pain | I started the injections after my surgery for endo. I started with the monthly injections and had a heavy period at first and cramping but have not had anything since. I did experience hot flashes but very minimal. my doc had me on add back therapy which I think helped with the side effects a lot because when I would forget to take it I experienced more of them. I have notice that my memory isnt very good sometimes. But over all this drug has helped imensely and I do not regret the decision. I havent really noticed even being on the drug (except when hot flashing) and it was been nice to be without a period and pain for the last 4 months. I did have some weight gain in the very beginning and so I began to workout daily and eat better and found that I could easily lose the weight and it also helped with the moodiness. I noticed that during what was supposed to be "that time of month" I was way more moody then normal. overall I recommend this drug to anyone who would like to start controlling there periods and pain instead of the other way around. | F | 20 | 4 months
| | 1/21/2010
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| 4 | Endo | I have been on Lupron for almost a year. I did 3 month shots for the first 9 months and have been on one month shots the last 3. At first, I had dryness and almost complete loss of sex drive - sex began to hurt and has not felt right since I started the shot. Now, I have gained almost 15 pounds and can't seem to lose it. My mood swings are worse on the one month shot. My short term memory is very bad. I have even wondered if I am experiencing early signs of Alzheimers. Lupron has helped tremendously for the pain and bleeding. I have zero pain and have not had any spotting or bleeding. Basically, horrible memory loss, low sex drive, dryness and pretty bad mood swings. | I would recommended this drug as a last resort before having a hysterectomy; however, it does work for the pain and suffering of endo. I feel like it can be handled as long as you know what you are getting into and possibly take an anxiety drug like Prozac to help with the mood swings. A healthy diet and daily exercise helps a lot, too with the weight gain. | F | 30 | 12 months
| | 1/20/2010
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| 4 | Endometriosis | At first I had a stuffy nose, headaches, sleeplessness, mood swings, (sore throat?), and extreme thirstiness. Only on my first month.. | I only started it a week ago but so far I am only experiencing cold symptoms. My doctor said it might make the pain flare up worse until the third month but it was a last resort. So far I would say go for it. | F | 17 | 7 days
| | 1/19/2010
| 3 | Severe Endometriosis | Very Moody! Very heavy breakthrough bleeding, joint pain, Bloating and headaches. | How long is the breakthrough bleeding suppose to last. I am going on my thrid week. | F | 41 | 3 months
| | 1/19/2010
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| 2 | Stage 4 Endometriosis | Hot flashes, night sweats, chills, severe fatigue, depression, loss of interest (in sex and pretty much everything else important to me), weakness (in general), bleeding and pelvic pain | I have only received (2) injections over a two month time span. After the first injection, I became very weak, tired and depressed and bled for two weeks non-stop. I could not even muster up enough energy to make phone calls or to properly care for myself. I am only a few days into injection number two and my symptoms have change a little. I am very fatigued and feel as though I could sleep for day, however, have insomnia. I am hungry but too tired to cook. I sweat so much that I have chills and I just feel bad in general. I have not had children, but want to proceed with a hysterectomy in order to feel some relief. I have given birth control and Lupron a chance but feel as though I am down to my last option. I suggest you try Lupron as iy may work for you, it just hasn't helped me :-( | F | 25 | 2 months
| | 1/19/2010
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| 4 | endometriosis,post-surgery | Hot flashes, joint pain and stiffness (severe), weight gain, vaginal infections, fatigue, insomnia. | Overall, I think the lack of pain and bleeding has been worth the side effects. I absolutely cannot seem to lose weight no matter how little I eat or how much I exercise, and it hurts. I guess this is a preview of my sixties? | F | 41 | 6 months
| | 1/18/2010
| 2 | Fibroid Tumors | Hypertension, chest pains, anxiety, loss of appetite, racy heartbeat, restlessness... | My Dr. prescribed Lupron to shrink tumors & reduce bleeding before hysterectomy. It's been 4 weeks since the shot and the bleeding has reduced but not stopped like i was told it would. I feel horrible. My Blood Pressure has gone up & im now on bp medication, it doesn't seem to be helping with the racy heartbeat nor the chest pains. I'm also taking Lorazepan for anxiety, that seems to help with the racy heartbeat & chest pains, but problem is as soon as it wears off, i'm back at square one. Dr. says to her knowledge hypertension and chest pains are not side effects associated with Lupron...... Is it just me? | F | 47 | 4 weeks
| | 1/15/2010
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| 3 | Endometriosis/Ovarian Cysts | Weight gain, hair thinning, moodiness, occasional headaches | After removing ovarian cysts, my doctor prescribed lupron injections for the next six months. I just had my fourth injection, and the side effects continue to cause me grief. I can tolerate the hot flashes and mood swings, but the weight gain and hair thinning are very discouraging. | F | 28 | 4 months
| | 1/9/2010
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| 4 | Endometriosis | Mood swings after the 1st and 2nd injections that have since resolved. Mild hot flashes, Mild hair thinning. Had one period after 1st injection and none since. I'm on injection 4 of 6. | Many of these reviews almost made me refuse the Lupron, but I'm glad I didn't. Its not bad at all, I feel just like I did before taking it, no big deal. Also - As far as weight gain is concerned, I started a diet/exercise program when I started Lupron and went from 145 to 125 with no problem :) | F | 24 | 4 months
| | 1/7/2010
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| 4 | prostate cancer | muscle atrophy, total loss of libido, lethargy, hot flashes, etc, etc | the muscle atrophy has been the biggest problem for me. even after stopping the treatments, i can't build any muscle mass and my libido is still shot. I took five 3-month shots and my PSA went from very high to very low. I had my last shot nearly 9 months ago and while my PSA is still low, I still feel like a middle aged woman (attempt at humor). I walk 3 miles a day to help keep my blood sugar under control and it is still a chore to complete. I am going to ask my oncologist if I can get a testosterone shot or something to help with the muscle atrophy. | M | 61 | 15 months
| | 1/7/2010
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| 3 | endomitriosis | hot flashes,joint pain,fatigue | i developed black spots under my eyes.was wondering if this happened to anyone else????please email me. | F | 36 | 1 years
| | 1/6/2010
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| 5 | Large Uterine Fibroids | I did not have any side effects from Lupron. | I had 9 Uterine Fibroids and was told abdominal surgery was my only option. I had read about the benefits of Lupron shrinking your uterus and fibroids prior to surgery as well as all the horror stories. I still discussed it with my doctor (specialist) as an option to have laproscopic surgery instead of abdominal if Lupron could help shrink them before hand. He was not very optomistic but said I could try since I was so fearful of open surgery. I had 1 shot per month for 3 months and it worked, I had a laproscopic hysterectomy 3 weeks ago and I feel great. Everyone reacts different to medication I had no side effects but was prepared for the worst. | F | 38 | 90 days
| | 1/5/2010
| 1 | breast cancer prevention | heart palpitations, anxiety, blurred vision, extreme depression, sucidal thoughts. | I would never give this drug to anyone. I thought the side effects were horrible and that is after already going through chemotherapy which i think was easier on me than taking this drug. | M | 38 | 7 months
| | 1/4/2010
| 2 | severe endometriosis | I received my first shot of the supposed two in October. I didn't experience any of the normal side effects only that I had a period for over a month and it was far from spotting. I received an additional dose just two weeks ago as my estrogen had not dropped. I am now bleeding heavy again, suffering from headaches, insomnia, bad mood swings, depression and the extreme urge to cry alot, general joint pain and stiffness in my neck. I'm scheduled for another endometrial biopsy in a couple weeks to check my levels and schedule a third shots. I'm scheduled for surgery following the now third was supposed to be second shot. | This is the second time I've taken Lupron the first time it went pretty normal my levels went down and they had me on a replacment hormone which made the side effects less dramatic. This time around has been horrible. Wondering if the diet I'm on is effecting me consist of alot of vitamins and natural herbs???? | F | 36 | 2 months
| | 12/29/2009
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| 4 | intestinal endometriosis | at first: mood swings, occasional hot flashes, extreme fatigue
now: Hot flashes every hour, zero sex drive, dryness, fatigue | Despite all that, I am virtually asymptomatic for the endometriosis. I have had 2 "attacks" since I started and none of the usual bowel issues at all that I had regularly for 15 years. | F | 37 | 3 months
| | 12/27/2009
| 5 | Endometriosis | hot flashes, weight gain | Took years to decide to got on this med, but it has helped me lead a normal life. Before going on lupron I missed at least 5 days from my work and social life each month and was on multiple pain killers and opiates each period. Add back therapy (estrogen and progesterone) has assisted with hot flashes. | F | 39 | 1 years
| | 12/20/2009
| 4 | severe endometriosis | hot flashes, water retention, wt gain, very fatigued, very nauseated, joint pain, emotional | 2nd time on lupron. 3month injection 5 weeks ago, surgery in april. increase in endo symptoms for the first 2 weeks - more pain, etc, but no other side effects. now i don't have any abdominal pain. however, i have terrible hot flashes all the time, i am either very nauseated or very hungry, my joints hurt and i have a continuous headache. butlast time i used lupron i had the same side effects and i was pain free or had minimal pain for 5 years after the last injection. | F | 26 | 5 weeks
| | 12/14/2009
| 4 | Part of IVF treatment | Miagranes increased.
SEVERE joint point pain, especially in my ankles.
The worst acne since I was a teenager.
Bloating.
Increased crying. | The only reason I took this medication is because it was part of my in-vitro fertilization protocol. It's been a rough 25 days & I just did my last injection tonight. | F | 37 | 25 days
| | 12/13/2009
| 3 | Ovarian cysts | Very bad mood swings,pain in my stomach, and headaches | I started noticing side effects within 16 hours. I have the worst mood swings, within a 45 min period I went from crying to yelling, back to crying and then fine. I am having a realy hard time with it and I am supposed to take this for 3 months. | F | 34 | 4 days
| | 12/13/2009
| 3 | yes | vaginal dryness,weight gain and fatigue | I took my first and only 3 month lupron injection 3 weeks ago.I have no complaints my doctor precribed me aygestion to offset some of the side effects of the lupron which has done it's job! I have also been taking multi vitamins everyday which he also suggested. I go to have my partial hystorectomy on dec. 28. | F | 39 | 18 days
| | 12/4/2009
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| 1 | Fibroids | Took one 1 shot of Lupron only, in preparation for minor fibroid surgery. Six weeks after the shot and three weeks after the surgery, I became bloated. I am still bloated four months later. Has anyone had this experience? I am miserable. | | F | 45 | 1 months
| | 12/4/2009
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| 4 | severe endometriosis | some weight gain, and my back hurts sometimes,no hotflashes | i got the lupron shot the first week in august,after having surgery for a 8cm mass that was pushing my uterus over after i had surgery i found out that i had endometriosis..thank god i already have a child because the doctor said it was pretty bad, started my period after surgery,as soon as i got the shot my period stopped immediately,but i spotted every day up until i got my 2nd 3 mth(just enough to wear a pantyliner) and last shot the beginning of this month,no spotting since..i got up until febuary and i'll be finished..so i just hope when i do get my period again they are mot as bad as before because if they are i have to get a complete hysterectomy,im just going to pray about, cause lord knows i cant go through with the pain again, it is just unbearable! i say do your research because i was hesite about trying it but it has helped alot,no periods which are a plus! side affects were bearable for me so far! good luck i got 2 more months will keep posting updates | F | 31 | 4 months
| | 11/30/2009
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| 3 | Severe endo and adenomyosis | fatigue, anxiety, depression (better the third month), hot flashes, night sweats that cause a lot of sleep disruption, bad short term memory. 3 months into it aged facial skin and fatigue are the worst remaining side effects. | Copious bleeding and worsening pains led to a terrible anemia. It was hysterectomy or this. Have been put on the Mirena IUD 2 weeks ago, the idea is that it begins working while the Lupron is still stopping the bleeding. (The Mirena alone can cause worse bleeding the first month or so). If this works, the Lupron gets completely flushed out and the Mirena leads to minor bleeding and relief until real menopause - it's been worth it, as I cherish keeping my uterus. However, the side effects the first 6-8 weeks were awful. I am juicing, taking B, C, D and calcium supplements but would love to know what else can be done. Will the aged skin go back to normal? | F | 41 | 3 months
| | 11/30/2009
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| 3 | endo, chronic pelvic pain from it | 1st month, spotting and a bit of depression. 2nd and 3rd month minimal spotting. Hot flashes within the first 7 days of tx. Sleeplessness, fatigue, forgetfulness (more so than usual, i think?), hair thinning, weight fluctuation, still chronic pain. Some endo relief. | I am not sure having a copay of 122 bucks per injection was worth it. Was put on high doses of pain pills (which i dont like to take) before & during the inj. I was a hyper person, & have noticed I feel a shell of myself. Pristiq made me sick, but another anti depression, Cymbalta, helped a little in the 30-60mg range. Last inj was around Halloween. I hope to persevere & be able to function again, & to lose some weight around my middle. I doubt i will get my 4 pack back, but at this point if i lose the tire around it, I will be happy. I am good for about 3 hours now if i go out, as long as it is not strenuous. Before and during the first few inj, I could not handle an hour. | F | 34 | 6 months
| | 11/29/2009
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| 4 | Very severe endometriosis | Mood swings (I cry a lot now), depression, some memory loss, hair loss, hot flashes and night sweats, some joint and muscle pain | I originally saw a doc about blood in my stool during my periods, which were absolutely horrible (But women are supposed to shut up and take it, right?) Turns out that I had a ever growing endometrioma that was obstructing my large intestines and my left ureter. Also, the endo was causing my appendix to obstruct another part of my intestines. I was (what felt like) rushed to surgery, had two sections of my intestines removed, endo cleaned up, and my appendix removed. I was given the 3 month shot of Lupron when I left the hospital, and I took my second three month shot about a month ago (I am scheduled for one more). The mood swings are rough, but doable, especially if you have an understanding support system. The hot flashes aren't fun. They put me on add-back therapy for a couple of weeks--Loestrin, in fact--which made me spot for 6 weeks, as well as make me feel as though my body was trying to have a period (though nowhere NEAR the kind of periods I use to have). The first shot of Lupron did not cause me to spot, so the docs took me off the add-back, so now I am just toughing it out. I feel much better these days, though it's hard to work out whether it's the Lupron or the surgery. The Lupron is very expensive, which could prevent some from finding relief with this drug. The spotting is annoying, and the hair loss makes me a little sad, but I'm hoping that none of this will be temporary. The best part about Lupron: no periods. | F | 29 | 4 months
| | 11/27/2009
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| 3 | Endometriosis | Mood swings, hot flashes, vaginal dryness,feeling achy all over, and Im still not the same and I have been off it for 3 months. | I was on the shot for 6 months and the side effects were rough to deal with. I have started my period back and I am hurting the same way I was before. | F | 22 | 6 months
| | 11/26/2009
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| 1 | Endometriosis | Weight gain, hot flashes, back and neck pain, joint and tissue pain all over, sesitivity all over, stiffness, fatigue. | Well, it's 2009 and I am STILL suffering from horrible side effects from Lupron taken in 2005! I have been to all kinds of specialist to try and find out how we can treat all my symtoms. Somehow Lupron changed my body after the 1st of 3 three shots. I can't find a doctor who will take the time to research this and all my testing has come back negative. My next appointment is with a Lyme Disease Doctor.
In my opinion, Lupron was NOT worth the side effects and didn't solve ANY of my intials problems either. Still have endometriosis and can't get pregnant! | F | 34 | 6 months
| | 11/23/2009
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| 4 | Prostate Cancer | Very sleepy and fatigued at different time periods of the day, especially after eating.Weight gain (32 pounds in 34 months), increased appitite, cold & hot flashes,some insomnia, irritable | Upon turning 50 my PSA WAS 53.6 and was diagnosed with stage 3 prostate cancer with a gleason score of 9. I recieved lupron and casodex for 34 months and 10 weeks of external beam radiation (imrt). My PSA went down to 0.02 and stayed there for about 6 to 8 months after the treatment stopped. After that it began to double avery 3 months at first, then after about 18 months it went from 6.4 to 15 in 6 weeks. I am now on both drugs again. Have been on them now for 6 weeks as of 11/16/09 and have not recieved the results of the blood test taken the other day. I am also trying MMS. Would like to find other choises as i am told my cancer is not cureable. | M | 50 | 34 months
| | 11/19/2009
| 5 | Fibroids | some hot flashes, but that's about it for me. | This gave me my life back! I went to ER with SEVERE abdominal pain and bleeding. I had sever anemia. I had to have blood transfusions it was so low. I was given the 3-month Lupron shot and after about 1 week my bleeding totally went away and the pain was gone. I was able to go on my scheduled Caribbean Cruise because of Lupron the next month. Without it I would have had to cancel it. This is temporary until I have my Fibroids removed. Moodiness and insomnia - I had these before I took Lupron. I highly recommend it, but realize that side effects are different for everyone. | F | 39 | 1 months
| | 11/18/2009
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| 5 | Severe Endometreosis | None | I was put on Lupron for severe Endo as a last ditch effort before a hysterectomy. I received 3 injections and it has worked beautifully - no mood swings, no hot flashes, no night sweats..nothing and the pain, heavy bleeding and bowel/bladder problems that I had from the endo are completely gone. I was hesitant to take the drug from all the negative feedback but I have to say I experienced none of the issues that others have complained of. I would recommend it to anyone with a similar problem. | F | 49 | 3 months
| | 11/13/2009
| 1 | uterine fibroids | hot flashes, vaginal dryness, all the little things they warn you about. THE MOST IMPORTANT THING THEY DID NOT EMPHASIZE WAS RESULTANT OSTEOPOROSIS!!! Do not take this drug. It is poison to your body. Do your own research, find a doc who will work with you. If a doc suggests Lupron, for any reason, to any person, man or woman, run, run, run! The problems you will deal with later in life because of this poison, are far worse than the symptoms you are treating now with Lupron. If you have already received the injections, start taking calcium and vitamin D now and don't stop. Also, get a bone density scan done! Every two years if you are found to have osteoporosis. Good luck to all who have become Lupron Victims. | | F | 49 | 3 months
| | 11/13/2009
| 4 | endometriosis | during treatment: constipation, hot flashes, acne, sleeplessness | Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice.
When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days.
It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain.
Did anyone continue expe | F | 28 | 6 months
| | 11/12/2009
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| 3 | ER positve Breast Cancer | I am taking Lupron as part of the Hormonal Treatement plan instead of taking Tamoxifin. Lupron as put me in "menopause" and enables me to take Arimedax for Post menopausal treatment. I have received the Lupron injections since 9/2005 and have no periods since. Would prefer not to be on this med as I am very concerned about the 'long-term' effects. | Pros: no periods, No Breast Cancer!!
Cons: weight gain especially in the mid section, water retention, insomnia (very bad), joint aches, back ache, hot flashes, and real difficulty with an exacorbation of depression with irriatability, low mood, some mood swings, impatient. This has been the most difficult piece with this medication. You really have to weigh the pros and cons as it can become a quality of life issue. For me it is Lupron with Depression symptoms and knowing that it is not likely that my Breast CA will return or stopping the med and concern of a reoccurance. | F | 35 | 4.3 years
| | 11/12/2009
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| 1 | endrometrios | It was the worst, I experience the worst side effects that any medicine should be allowed to have. Extreme mood swings, Intense hot flashes and night sweats frequently, extreme weight gain(15 lbs)within 2 months and still trying to lose it...hair loss and foggy mind. I went to my general practioner and he described Wellbuton to counteract the Lupron. I will deal with the pain when ever my cycle resumes. | | M | 44 | 3 months
| | 11/12/2009
| 1 | endometriosis | debilitating bone/joint pain | Please use this drug with caution. My last injection was over a year ago, and my pain is still severe. I have seen three specialists and have undergone extensive testing. They have all reluctantly agreed that the Lupron is causing my pain. | F | 31 | 5 months
| | 11/12/2009
| 1 | prostate cancer spread to bones | My father had three injections and became very fatigues and depressed. He took his life a month and half after the last injection of Lupron. He had a heart condition also and was given the drug anyway. It has been shown to cause cardiac arrest. THe nurse practioner at Thomas Jefferson Urology in Philadelphia, PA said she saw my father was depressed and she continued to give him the injections. She was not supervised by an MD which is permitted in Pennsylvania. Before the shots, father was walking around Philly. After he was too tired and depressed to do anything. Nurse also gave him Casodex which combined with Lupron severely lowers testosterone levels. Dr. Sui-Long Yao of Cancer Institute of New Jersey did a study that shows Lupron doesn't increase lives of prostate cancer people and seriously damages the quality of their lives. The Los Angeles Times newspaper reported those receiving Lupron had a 17.4 percent death rate vs. those not receiving it of a 19.9 percent death rat | all of his teeth would have to be pulled because Zometa causes decay of the jaw bone. She said my father didn't want that to happen to him and she didn't refer my father to anyone else for chemotherapy when he asked if there was another course of treatment. She let him leave very depressed and tired from the Lupron and Casodex. The supervising doctor, Dr Goldman, of the nurse practioner, nurse Darlene Bewick,said to me he didn't know about my father's care because the nurse saw him. he didn't even know my Dad had bone cancer from the prostate. Do not take Lupron. It causes severe damages and has caused my father's death. Doctors keep giving the drug. Please email me: Cheryl. | M | 88 | 4 months
| | 11/8/2009
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| 4 | Endometriosis | Hot flashes, real bad muscle aches, nausea, headaches, mood swings, fatigue. | I had an ovarian cyst removed in May 2009, when the doctor found some endometriosis. Started having real bad symptoms of the endo in August, got my first Lupron shot at the end of September and I just got my second shot four days ago. I saw my college's health services today because I thought I had the flu, I'm so achy and exhausted, but I don't have a fever or anything so I think they're likely symptoms of the lupron. I am on the pill that came with the shot, take that every morning and I think its better with that because I missed one once and I was MISERABLE. I think I've had "hot flashes", in the sense that I sweat more than usual and sometimes feel very warm, but nothing like older women I know who are actually going through natural menopause. I feel TERRIBLE today, but I guess body aches is better than being doubled over in severe abdominal pain every other day? | F | 20 | 1 months
| | 11/3/2009
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