There are 493 ratings for the drug: LUPRON in the Askapatient database.

Key to ratings for lupron: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken		Date Added
				F  M
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3	Endo	Headaches, MILD confusion/memory loss, night sweats, mild hot flashes, mild sadness, mild acne & weight gain.	It's only been 1 week but so far the side effects have been mild w/ the exception of headaches. They're a daily occurrence, get more intense each day. I'm on once/mo. for 6 mos., take 5 mg progestin daily as "add back". Stage 3 endo, diagnosed in Dec. Was on the pill for about 18 mos w/out improvement so doc suggested lupron. I'd actually not be too bothered by most side effects, but the weight gain, acne & mood swings. I struggle w/ my mood as it is, & w/ weight so I'm not impressed w/ gaining about 3 lbs in a week. The weirdest thing is the false 'hunger' I have. It's quite bizarre; I'm sorta hungry & full at the same time. I'll eat & be full but 30 min later get almost like hunger pangs; yet I'm STILL FULL! It's nuts! Also noticed I'm actually eating a lil' less cuz I get nauseated bout 1/2way into a meal probably 1/2 the time I eat. Haven't had TOO many hot flashes; been pretty tolerable but I've gotten night sweats & woke up SOAKED in the a.m. past couple days. Feel overall kinda tired & forgot what I was doing mid-task a couple times. Still in the stage where estrogen is actually "surging" before it drops so I guess side effects will probably intensify the next few wks. I feel awful for those who had such a negative experience but for ME so far I've noticed my pain's already reduced. Started shot 1st day of my period & it only lasted 1.5 days vs. a "normal" week-long cycle. I'm keeping my fingers crossed that ben	F	29	1 weeks		2/5/2010
1	endomitriosis	I was givin lupron to help early endo. It destroyed my life. I had horrible hot flashes, extreem bone pain, muscle spasums and achs, terrible mood swings and messed up my thinking. Had short term memory loss. I still continued to have pain threw the shot, it was not good for me and i only ahd the shot once. I was on my peroid for three weeks straight then didnt have it for three months		F	17	1 times		2/3/2010 Email
3	Fibroids	Extreme Hot Flashes; High Blood Pressure	Though the bleedng has stopped after the first shot; my blood pressure has shot up to 160/90. Has anyone else had this happen? Make sure you check your blood pressure while on this drug.	F	53	2 months		1/27/2010 Email
1	Hypothyroidism and PCOS	Mood swings- super emotional, memory loss/confusion, spacey,	Treatment done in June and July 2009. It wreaked havoc on my body I haven't been the same since. I had gotten to the point where I was finally losing weight and I was feeling okay. I think I just needed to be taken off of birth control. My body doesn't like pills with hormones. Instead, I got some doses of lupron. AHH!!! Anyone know anything about lawsuits?	F	24	2 months		1/25/2010
5	Fibroids and endometriosis	HOT hot flashes, vaginal dryness, dry skin and eyes, occasional night sweats.	WELL worth the inconvenience and side effects, Lupron really did the trick in shrinking all my fibroids (I had about five large ones) and shutting down the endo. I had surgery first, followed by six months of Lupron Depot injections. I never had a recurrence of either the endometriosis or the fibroids. I would recommend Lupron to anyone with severe bleeding problems and for whom hysterectomy was the first solution given by a doctor. The first three doctors I saw wanted to do an immediate hysterectomy and never mentioned Lupron. The fourth doctor suggested surgery followed by Lupron -- we would have done it the other way around except I was bleeding so much that I was on the edge of not being an acceptable candidate for surgery because my hemocrit levels were so low. I, too, have chemotherapy experience from a late-stage childhood cancer -- 11 months of MOPP chemo, which was nasty indeed. The Lupron wasn't even close to chemo, not in the same universe. And the Lupron side effects are temporary, unlike chemo and radiation side effects that I'm still dealing with 30 years later. If you believe as I do that keeping your uterus intact is important (talk to older women who have had hysterectomies and many years to live with the aftereffects -- younger women won't experience as many problems), then I truly can't recommend Lupron enough.	F	47	6 months		1/22/2010 Email
3	Fibroids	I became very emotional. Cry at a drop of a hat; have become very depressed or angry at times. loss of short term memory, extreme fatigue, joint pain. Night sweats and hot flashes; hair loss	This drug is, in my opinion, a last resort type of drug. If I didn't need the benefits of this drug, I would NOT EVER take this drug again. I'm crossing my fingers that it has done what my doctor stated it would do...please because I don't want to do this again	F	31	3 months		1/22/2010
4	Endo/ Polycystic ovarian syndrome	Hot flashes, cramps, short term memory loss, dryness, insomnia, moodiness, lower back pain	I started the injections after my surgery for endo. I started with the monthly injections and had a heavy period at first and cramping but have not had anything since. I did experience hot flashes but very minimal. my doc had me on add back therapy which I think helped with the side effects a lot because when I would forget to take it I experienced more of them. I have notice that my memory isnt very good sometimes. But over all this drug has helped imensely and I do not regret the decision. I havent really noticed even being on the drug (except when hot flashing) and it was been nice to be without a period and pain for the last 4 months. I did have some weight gain in the very beginning and so I began to workout daily and eat better and found that I could easily lose the weight and it also helped with the moodiness. I noticed that during what was supposed to be "that time of month" I was way more moody then normal. overall I recommend this drug to anyone who would like to start controlling there periods and pain instead of the other way around.	F	20	4 months		1/21/2010 Email
4	Endo	I have been on Lupron for almost a year. I did 3 month shots for the first 9 months and have been on one month shots the last 3. At first, I had dryness and almost complete loss of sex drive - sex began to hurt and has not felt right since I started the shot. Now, I have gained almost 15 pounds and can't seem to lose it. My mood swings are worse on the one month shot. My short term memory is very bad. I have even wondered if I am experiencing early signs of Alzheimers. Lupron has helped tremendously for the pain and bleeding. I have zero pain and have not had any spotting or bleeding. Basically, horrible memory loss, low sex drive, dryness and pretty bad mood swings.	I would recommended this drug as a last resort before having a hysterectomy; however, it does work for the pain and suffering of endo. I feel like it can be handled as long as you know what you are getting into and possibly take an anxiety drug like Prozac to help with the mood swings. A healthy diet and daily exercise helps a lot, too with the weight gain.	F	30	12 months		1/20/2010 Email
4	Endometriosis	At first I had a stuffy nose, headaches, sleeplessness, mood swings, (sore throat?), and extreme thirstiness. Only on my first month..	I only started it a week ago but so far I am only experiencing cold symptoms. My doctor said it might make the pain flare up worse until the third month but it was a last resort. So far I would say go for it.	F	17	7 days		1/19/2010
3	Severe Endometriosis	Very Moody! Very heavy breakthrough bleeding, joint pain, Bloating and headaches.	How long is the breakthrough bleeding suppose to last. I am going on my thrid week.	F	41	3 months		1/19/2010 Email
2	Stage 4 Endometriosis	Hot flashes, night sweats, chills, severe fatigue, depression, loss of interest (in sex and pretty much everything else important to me), weakness (in general), bleeding and pelvic pain	I have only received (2) injections over a two month time span. After the first injection, I became very weak, tired and depressed and bled for two weeks non-stop. I could not even muster up enough energy to make phone calls or to properly care for myself. I am only a few days into injection number two and my symptoms have change a little. I am very fatigued and feel as though I could sleep for day, however, have insomnia. I am hungry but too tired to cook. I sweat so much that I have chills and I just feel bad in general. I have not had children, but want to proceed with a hysterectomy in order to feel some relief. I have given birth control and Lupron a chance but feel as though I am down to my last option. I suggest you try Lupron as iy may work for you, it just hasn't helped me :-(	F	25	2 months		1/19/2010 Email
4	endometriosis,post-surgery	Hot flashes, joint pain and stiffness (severe), weight gain, vaginal infections, fatigue, insomnia.	Overall, I think the lack of pain and bleeding has been worth the side effects. I absolutely cannot seem to lose weight no matter how little I eat or how much I exercise, and it hurts. I guess this is a preview of my sixties?	F	41	6 months		1/18/2010
2	Fibroid Tumors	Hypertension, chest pains, anxiety, loss of appetite, racy heartbeat, restlessness...	My Dr. prescribed Lupron to shrink tumors & reduce bleeding before hysterectomy. It's been 4 weeks since the shot and the bleeding has reduced but not stopped like i was told it would. I feel horrible. My Blood Pressure has gone up & im now on bp medication, it doesn't seem to be helping with the racy heartbeat nor the chest pains. I'm also taking Lorazepan for anxiety, that seems to help with the racy heartbeat & chest pains, but problem is as soon as it wears off, i'm back at square one. Dr. says to her knowledge hypertension and chest pains are not side effects associated with Lupron...... Is it just me?	F	47	4 weeks		1/15/2010 Email
3	Endometriosis/Ovarian Cysts	Weight gain, hair thinning, moodiness, occasional headaches	After removing ovarian cysts, my doctor prescribed lupron injections for the next six months. I just had my fourth injection, and the side effects continue to cause me grief. I can tolerate the hot flashes and mood swings, but the weight gain and hair thinning are very discouraging.	F	28	4 months		1/9/2010 Email
4	Endometriosis	Mood swings after the 1st and 2nd injections that have since resolved. Mild hot flashes, Mild hair thinning. Had one period after 1st injection and none since. I'm on injection 4 of 6.	Many of these reviews almost made me refuse the Lupron, but I'm glad I didn't. Its not bad at all, I feel just like I did before taking it, no big deal. Also - As far as weight gain is concerned, I started a diet/exercise program when I started Lupron and went from 145 to 125 with no problem :)	F	24	4 months		1/7/2010 Email
4	prostate cancer	muscle atrophy, total loss of libido, lethargy, hot flashes, etc, etc	the muscle atrophy has been the biggest problem for me. even after stopping the treatments, i can't build any muscle mass and my libido is still shot. I took five 3-month shots and my PSA went from very high to very low. I had my last shot nearly 9 months ago and while my PSA is still low, I still feel like a middle aged woman (attempt at humor). I walk 3 miles a day to help keep my blood sugar under control and it is still a chore to complete. I am going to ask my oncologist if I can get a testosterone shot or something to help with the muscle atrophy.	M	61	15 months		1/7/2010 Email
3	endomitriosis	hot flashes,joint pain,fatigue	i developed black spots under my eyes.was wondering if this happened to anyone else????please email me.	F	36	1 years		1/6/2010 Email
5	Large Uterine Fibroids	I did not have any side effects from Lupron.	I had 9 Uterine Fibroids and was told abdominal surgery was my only option. I had read about the benefits of Lupron shrinking your uterus and fibroids prior to surgery as well as all the horror stories. I still discussed it with my doctor (specialist) as an option to have laproscopic surgery instead of abdominal if Lupron could help shrink them before hand. He was not very optomistic but said I could try since I was so fearful of open surgery. I had 1 shot per month for 3 months and it worked, I had a laproscopic hysterectomy 3 weeks ago and I feel great. Everyone reacts different to medication I had no side effects but was prepared for the worst.	F	38	90 days		1/5/2010
1	breast cancer prevention	heart palpitations, anxiety, blurred vision, extreme depression, sucidal thoughts.	I would never give this drug to anyone. I thought the side effects were horrible and that is after already going through chemotherapy which i think was easier on me than taking this drug.	M	38	7 months		1/4/2010
2	severe endometriosis	I received my first shot of the supposed two in October. I didn't experience any of the normal side effects only that I had a period for over a month and it was far from spotting. I received an additional dose just two weeks ago as my estrogen had not dropped. I am now bleeding heavy again, suffering from headaches, insomnia, bad mood swings, depression and the extreme urge to cry alot, general joint pain and stiffness in my neck. I'm scheduled for another endometrial biopsy in a couple weeks to check my levels and schedule a third shots. I'm scheduled for surgery following the now third was supposed to be second shot.	This is the second time I've taken Lupron the first time it went pretty normal my levels went down and they had me on a replacment hormone which made the side effects less dramatic. This time around has been horrible. Wondering if the diet I'm on is effecting me consist of alot of vitamins and natural herbs????	F	36	2 months		12/29/2009 Email
4	intestinal endometriosis	at first: mood swings, occasional hot flashes, extreme fatigue now: Hot flashes every hour, zero sex drive, dryness, fatigue	Despite all that, I am virtually asymptomatic for the endometriosis. I have had 2 "attacks" since I started and none of the usual bowel issues at all that I had regularly for 15 years.	F	37	3 months		12/27/2009
5	Endometriosis	hot flashes, weight gain	Took years to decide to got on this med, but it has helped me lead a normal life. Before going on lupron I missed at least 5 days from my work and social life each month and was on multiple pain killers and opiates each period. Add back therapy (estrogen and progesterone) has assisted with hot flashes.	F	39	1 years		12/20/2009
4	severe endometriosis	hot flashes, water retention, wt gain, very fatigued, very nauseated, joint pain, emotional	2nd time on lupron. 3month injection 5 weeks ago, surgery in april. increase in endo symptoms for the first 2 weeks - more pain, etc, but no other side effects. now i don't have any abdominal pain. however, i have terrible hot flashes all the time, i am either very nauseated or very hungry, my joints hurt and i have a continuous headache. butlast time i used lupron i had the same side effects and i was pain free or had minimal pain for 5 years after the last injection.	F	26	5 weeks		12/14/2009
4	Part of IVF treatment	Miagranes increased. SEVERE joint point pain, especially in my ankles. The worst acne since I was a teenager. Bloating. Increased crying.	The only reason I took this medication is because it was part of my in-vitro fertilization protocol. It's been a rough 25 days & I just did my last injection tonight.	F	37	25 days		12/13/2009
3	Ovarian cysts	Very bad mood swings,pain in my stomach, and headaches	I started noticing side effects within 16 hours. I have the worst mood swings, within a 45 min period I went from crying to yelling, back to crying and then fine. I am having a realy hard time with it and I am supposed to take this for 3 months.	F	34	4 days		12/13/2009
3	yes	vaginal dryness,weight gain and fatigue	I took my first and only 3 month lupron injection 3 weeks ago.I have no complaints my doctor precribed me aygestion to offset some of the side effects of the lupron which has done it's job! I have also been taking multi vitamins everyday which he also suggested. I go to have my partial hystorectomy on dec. 28.	F	39	18 days		12/4/2009 Email
1	Fibroids	Took one 1 shot of Lupron only, in preparation for minor fibroid surgery. Six weeks after the shot and three weeks after the surgery, I became bloated. I am still bloated four months later. Has anyone had this experience? I am miserable.		F	45	1 months		12/4/2009 Email
4	severe endometriosis	some weight gain, and my back hurts sometimes,no hotflashes	i got the lupron shot the first week in august,after having surgery for a 8cm mass that was pushing my uterus over after i had surgery i found out that i had endometriosis..thank god i already have a child because the doctor said it was pretty bad, started my period after surgery,as soon as i got the shot my period stopped immediately,but i spotted every day up until i got my 2nd 3 mth(just enough to wear a pantyliner) and last shot the beginning of this month,no spotting since..i got up until febuary and i'll be finished..so i just hope when i do get my period again they are mot as bad as before because if they are i have to get a complete hysterectomy,im just going to pray about, cause lord knows i cant go through with the pain again, it is just unbearable! i say do your research because i was hesite about trying it but it has helped alot,no periods which are a plus! side affects were bearable for me so far! good luck i got 2 more months will keep posting updates	F	31	4 months		11/30/2009 Email
3	Severe endo and adenomyosis	fatigue, anxiety, depression (better the third month), hot flashes, night sweats that cause a lot of sleep disruption, bad short term memory. 3 months into it aged facial skin and fatigue are the worst remaining side effects.	Copious bleeding and worsening pains led to a terrible anemia. It was hysterectomy or this. Have been put on the Mirena IUD 2 weeks ago, the idea is that it begins working while the Lupron is still stopping the bleeding. (The Mirena alone can cause worse bleeding the first month or so). If this works, the Lupron gets completely flushed out and the Mirena leads to minor bleeding and relief until real menopause - it's been worth it, as I cherish keeping my uterus. However, the side effects the first 6-8 weeks were awful. I am juicing, taking B, C, D and calcium supplements but would love to know what else can be done. Will the aged skin go back to normal?	F	41	3 months		11/30/2009 Email
3	endo, chronic pelvic pain from it	1st month, spotting and a bit of depression. 2nd and 3rd month minimal spotting. Hot flashes within the first 7 days of tx. Sleeplessness, fatigue, forgetfulness (more so than usual, i think?), hair thinning, weight fluctuation, still chronic pain. Some endo relief.	I am not sure having a copay of 122 bucks per injection was worth it. Was put on high doses of pain pills (which i dont like to take) before & during the inj. I was a hyper person, & have noticed I feel a shell of myself. Pristiq made me sick, but another anti depression, Cymbalta, helped a little in the 30-60mg range. Last inj was around Halloween. I hope to persevere & be able to function again, & to lose some weight around my middle. I doubt i will get my 4 pack back, but at this point if i lose the tire around it, I will be happy. I am good for about 3 hours now if i go out, as long as it is not strenuous. Before and during the first few inj, I could not handle an hour.	F	34	6 months		11/29/2009 Email
4	Very severe endometriosis	Mood swings (I cry a lot now), depression, some memory loss, hair loss, hot flashes and night sweats, some joint and muscle pain	I originally saw a doc about blood in my stool during my periods, which were absolutely horrible (But women are supposed to shut up and take it, right?) Turns out that I had a ever growing endometrioma that was obstructing my large intestines and my left ureter. Also, the endo was causing my appendix to obstruct another part of my intestines. I was (what felt like) rushed to surgery, had two sections of my intestines removed, endo cleaned up, and my appendix removed. I was given the 3 month shot of Lupron when I left the hospital, and I took my second three month shot about a month ago (I am scheduled for one more). The mood swings are rough, but doable, especially if you have an understanding support system. The hot flashes aren't fun. They put me on add-back therapy for a couple of weeks--Loestrin, in fact--which made me spot for 6 weeks, as well as make me feel as though my body was trying to have a period (though nowhere NEAR the kind of periods I use to have). The first shot of Lupron did not cause me to spot, so the docs took me off the add-back, so now I am just toughing it out. I feel much better these days, though it's hard to work out whether it's the Lupron or the surgery. The Lupron is very expensive, which could prevent some from finding relief with this drug. The spotting is annoying, and the hair loss makes me a little sad, but I'm hoping that none of this will be temporary. The best part about Lupron: no periods.	F	29	4 months		11/27/2009 Email
3	Endometriosis	Mood swings, hot flashes, vaginal dryness,feeling achy all over, and Im still not the same and I have been off it for 3 months.	I was on the shot for 6 months and the side effects were rough to deal with. I have started my period back and I am hurting the same way I was before.	F	22	6 months		11/26/2009 Email
1	Endometriosis	Weight gain, hot flashes, back and neck pain, joint and tissue pain all over, sesitivity all over, stiffness, fatigue.	Well, it's 2009 and I am STILL suffering from horrible side effects from Lupron taken in 2005! I have been to all kinds of specialist to try and find out how we can treat all my symtoms. Somehow Lupron changed my body after the 1st of 3 three shots. I can't find a doctor who will take the time to research this and all my testing has come back negative. My next appointment is with a Lyme Disease Doctor. In my opinion, Lupron was NOT worth the side effects and didn't solve ANY of my intials problems either. Still have endometriosis and can't get pregnant!	F	34	6 months		11/23/2009 Email
4	Prostate Cancer	Very sleepy and fatigued at different time periods of the day, especially after eating.Weight gain (32 pounds in 34 months), increased appitite, cold & hot flashes,some insomnia, irritable	Upon turning 50 my PSA WAS 53.6 and was diagnosed with stage 3 prostate cancer with a gleason score of 9. I recieved lupron and casodex for 34 months and 10 weeks of external beam radiation (imrt). My PSA went down to 0.02 and stayed there for about 6 to 8 months after the treatment stopped. After that it began to double avery 3 months at first, then after about 18 months it went from 6.4 to 15 in 6 weeks. I am now on both drugs again. Have been on them now for 6 weeks as of 11/16/09 and have not recieved the results of the blood test taken the other day. I am also trying MMS. Would like to find other choises as i am told my cancer is not cureable.	M	50	34 months		11/19/2009
5	Fibroids	some hot flashes, but that's about it for me.	This gave me my life back! I went to ER with SEVERE abdominal pain and bleeding. I had sever anemia. I had to have blood transfusions it was so low. I was given the 3-month Lupron shot and after about 1 week my bleeding totally went away and the pain was gone. I was able to go on my scheduled Caribbean Cruise because of Lupron the next month. Without it I would have had to cancel it. This is temporary until I have my Fibroids removed. Moodiness and insomnia - I had these before I took Lupron. I highly recommend it, but realize that side effects are different for everyone.	F	39	1 months		11/18/2009 Email
5	Severe Endometreosis	None	I was put on Lupron for severe Endo as a last ditch effort before a hysterectomy. I received 3 injections and it has worked beautifully - no mood swings, no hot flashes, no night sweats..nothing and the pain, heavy bleeding and bowel/bladder problems that I had from the endo are completely gone. I was hesitant to take the drug from all the negative feedback but I have to say I experienced none of the issues that others have complained of. I would recommend it to anyone with a similar problem.	F	49	3 months		11/13/2009
1	uterine fibroids	hot flashes, vaginal dryness, all the little things they warn you about. THE MOST IMPORTANT THING THEY DID NOT EMPHASIZE WAS RESULTANT OSTEOPOROSIS!!! Do not take this drug. It is poison to your body. Do your own research, find a doc who will work with you. If a doc suggests Lupron, for any reason, to any person, man or woman, run, run, run! The problems you will deal with later in life because of this poison, are far worse than the symptoms you are treating now with Lupron. If you have already received the injections, start taking calcium and vitamin D now and don't stop. Also, get a bone density scan done! Every two years if you are found to have osteoporosis. Good luck to all who have become Lupron Victims.		F	49	3 months		11/13/2009
4	endometriosis	during treatment: constipation, hot flashes, acne, sleeplessness	Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice. When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days. It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain. Did anyone continue expe	F	28	6 months		11/12/2009 Email
3	ER positve Breast Cancer	I am taking Lupron as part of the Hormonal Treatement plan instead of taking Tamoxifin. Lupron as put me in "menopause" and enables me to take Arimedax for Post menopausal treatment. I have received the Lupron injections since 9/2005 and have no periods since. Would prefer not to be on this med as I am very concerned about the 'long-term' effects.	Pros: no periods, No Breast Cancer!! Cons: weight gain especially in the mid section, water retention, insomnia (very bad), joint aches, back ache, hot flashes, and real difficulty with an exacorbation of depression with irriatability, low mood, some mood swings, impatient. This has been the most difficult piece with this medication. You really have to weigh the pros and cons as it can become a quality of life issue. For me it is Lupron with Depression symptoms and knowing that it is not likely that my Breast CA will return or stopping the med and concern of a reoccurance.	F	35	4.3 years		11/12/2009 Email
1	endrometrios	It was the worst, I experience the worst side effects that any medicine should be allowed to have. Extreme mood swings, Intense hot flashes and night sweats frequently, extreme weight gain(15 lbs)within 2 months and still trying to lose it...hair loss and foggy mind. I went to my general practioner and he described Wellbuton to counteract the Lupron. I will deal with the pain when ever my cycle resumes.		M	44	3 months		11/12/2009
1	endometriosis	debilitating bone/joint pain	Please use this drug with caution. My last injection was over a year ago, and my pain is still severe. I have seen three specialists and have undergone extensive testing. They have all reluctantly agreed that the Lupron is causing my pain.	F	31	5 months		11/12/2009
1	prostate cancer spread to bones	My father had three injections and became very fatigues and depressed. He took his life a month and half after the last injection of Lupron. He had a heart condition also and was given the drug anyway. It has been shown to cause cardiac arrest. THe nurse practioner at Thomas Jefferson Urology in Philadelphia, PA said she saw my father was depressed and she continued to give him the injections. She was not supervised by an MD which is permitted in Pennsylvania. Before the shots, father was walking around Philly. After he was too tired and depressed to do anything. Nurse also gave him Casodex which combined with Lupron severely lowers testosterone levels. Dr. Sui-Long Yao of Cancer Institute of New Jersey did a study that shows Lupron doesn't increase lives of prostate cancer people and seriously damages the quality of their lives. The Los Angeles Times newspaper reported those receiving Lupron had a 17.4 percent death rate vs. those not receiving it of a 19.9 percent death rat	all of his teeth would have to be pulled because Zometa causes decay of the jaw bone. She said my father didn't want that to happen to him and she didn't refer my father to anyone else for chemotherapy when he asked if there was another course of treatment. She let him leave very depressed and tired from the Lupron and Casodex. The supervising doctor, Dr Goldman, of the nurse practioner, nurse Darlene Bewick,said to me he didn't know about my father's care because the nurse saw him. he didn't even know my Dad had bone cancer from the prostate. Do not take Lupron. It causes severe damages and has caused my father's death. Doctors keep giving the drug. Please email me: Cheryl.	M	88	4 months		11/8/2009 Email
4	Endometriosis	Hot flashes, real bad muscle aches, nausea, headaches, mood swings, fatigue.	I had an ovarian cyst removed in May 2009, when the doctor found some endometriosis. Started having real bad symptoms of the endo in August, got my first Lupron shot at the end of September and I just got my second shot four days ago. I saw my college's health services today because I thought I had the flu, I'm so achy and exhausted, but I don't have a fever or anything so I think they're likely symptoms of the lupron. I am on the pill that came with the shot, take that every morning and I think its better with that because I missed one once and I was MISERABLE. I think I've had "hot flashes", in the sense that I sweat more than usual and sometimes feel very warm, but nothing like older women I know who are actually going through natural menopause. I feel TERRIBLE today, but I guess body aches is better than being doubled over in severe abdominal pain every other day?	F	20	1 months		11/3/2009 Email
4	Lower Androgen level	mood swings, hot flashes, night sweats, headaches, nausea, light-headed, 1st month still got period	I took 2 one month injections to lower my androgen (testosterone) levels- it was high for me being a female. After 2 months it was lowered and I am supposed to check it again soon, so hopefully this works long-term. All of the symptoms were relatively mild and not all the time. However, I felt pretty weird and out of it the whole time. I did a lot of research online and there are a whole lot of horror stories, but it really wasn't that bad for me. I lived with someone else who took it for inducing menopause and she had more severe symptoms. She was also on 3-month doses and said they stayed in her system too long. If my levels continue to stay normal long-term, this was well worth it and I would do it again, but not for any extended period of time.	F	23	2 months		10/29/2009
4	Fiboids	Hot flashes. Mood swings. Spotting at first and then no period at all. Mostly hot flashes.	I have a 17 cm fibroid. I am taking a 3 month injection to shrink the fibroid to Da Vinci operable size. PLEASE look into the Da Vinci surgery. The recovery time is 2 weeks and is much less invasive. Most doctors don't know how to do this surgery. Keep searching until you find one that does.	F	34	6 weeks		10/18/2009
1	Uterine Fibroids	I started having hot flashes at the age of 32. Hot flashes, rapid weight gain, vision changes, acne, muscle and joint pain, extreme aggitation, heart palpitations, thoughts of causing others harm, short term memory loss, diagnosed with high blood pressure and arthritis, dizziness, shortness of breath, chest pains, looks like I am 5 months pregnant, and a daily migranes are all that come to mind at the moment. BUT I am sure the only reason I can't name more is because of the memory loss.	Poison to body and soul. The temporary relief is NOT worth the long term suffering caused by Lupron!! I suppose the only thing that may make this nightmare worth it is if you are trying to conceive or you are being treated for a terminal illness. I am praying for all of us and even those that have read all of these posted warning and unwisely allows your doctor to convince you to alter your life forever. I only had fibroids and now I feel like an 80 year old woman. My daughter wants to know why I don't play with her anymore. Every day I have to tell them to be quiet because mommy doesn't feel good today maybe tomorrow. The Devil is a lie, I am going to play with my girls again. In the name of Jesus!!!!!!!!!!!	F	45	3 months		10/12/2009 Email
5	Endometriosis	Joint Pain, weight gain, hot flashes	I was on Lupron in 2001 for my endo pain and i LOVED IT! My pain was gone and although the side effects weren't fun it was worth it. I had a son in 2004 and 2006. I started feeling endo pains last year and I talked to my doctor about another round of lupron. I just got my 1st 3 month shot this week and i am excited. Think about it - i got the shot in 2001 and started feeling pain again in 2008? Seven years of relief! Lupron is wonderful and I say try it!	F	29	6 months		10/9/2009
3	Anomiosis and Stage 5 endo	I gained weight, always tired, horrible horrible mood swings, anxiety, depression, always crying, bruise easily, acne wich I have nver had in my life.	I am 21 years old I started the lupron injections five months ago because I have anomiosis amd endometriosis.I have been sick since i was eleven. I have had five surgeries nothing has helped so lupron was the last thing to try. I am on a low dose of it. I absolutly hate it. I thougt i was getting better but this month which is my 5th month is bad Im in costant pain. Im very emotional. I just feel so slow and depressed. Im only on it another month Im just wondering what happens when I go off.	F	21	5 months		10/9/2009 Email
3	ENDOMETRIOSIS-PCOS	MIGRAINE, JOINT PAIN, BLOATING	I have taken 1 3 month shot and due for my second. At first, my symptoms of endo were really bad if not worse then I have noticed in the last couple of weeks that the pelvic pain is gone but the joint pain and abdominal bloating are my biggest problems now. I had a couple of migraines the first month but none since then. over all I think Lupron has helped with my endo but I am now concerned about joint pain and the swelling of my tummy. I plan on seeking advice from an endocrinologist (not sure if I spelled that correctly) since I have PCOS as well. Also will be making an appointment to see a gastroenterologist to check out the bloating.	F	35	3 months		10/5/2009 Email
1	endometrosis/ pelvic pain	I only got the shot 5 days ago and i am experiencing many side effects. Hot flashes and cold sweats started the day after. I have been very dizzy i can get half way through straightening my hair and have to sit down. I have ate 1 can of chicken noodle soup,6 saltine crackers, and a half a sandwich in the last 5 days. I have also had a very very bad headache the last 5 days. I have missed two days of work this week because of how nausiated i have felt which started the day after the shot was givin.	This was only my first shot and i am already having so many problems with it. I dont think i am going to continue getting these injections because i am afraid the more i put into my body the worse it will get.	F	20	5 days		10/4/2009 Email
1	severe endometriosis	Debilitating joint and bone pain. After taking 1 three month injection of Lupron, I have since been diagnosed with Rheumatoid Arthritis and the blood disorder Polycythemia Vera within a year. It did stop my cycle for 6 months so I did have temporary relief from the endo.	I do not recommend this drug to anyone. Even with an add back. Especially anyone that already has a anti-inflammatory disorder or disease. I never experienced such adverse side effects from a medication until Lupron. Horrible.	F	36	3 months		10/2/2009
1	endometriosis	Hair loss, memory loss, severe hot flashes	I will say that after I was off Lupron, I got preganant 5 months later. However, I would NOT recommend Lupron. This drug put me into early menopause the second I got off it. My docs have said that my body is actually 15yrs older than my age. I have very little short term memory, my hot flashes have never gone away and my last shot was 18 yrs ago. Now my daughter has started having hot flashes at the age of 14 and strongly believe it was because of the Lupron still in my system. I had endometriosis so bad that the doctors filmed my surgery and took it around the world for training classes. Ladies, get the hystorectomy!!! Yes, you'll feel better, still lose your hair and so on. If you have endo, don't keep the ovaries because the endo will still live. All the pain is gone except for the side effects of the Lupron. Several years ago there was a class action law suit againt the use of Lupron. You had to sign up for compensation however all the news regarding this just stopped being posted. I gave up and figured I got my daughter and will just deal with the worst of it the way I always have. If you can survive ENDOMETRIOSIS, you can survive anything! Can I hear an Amen??	F	46	6 months		10/1/2009
5	Endometriosis	Hot flashes, easily irritated, more emotional	I have to ask myself why I put off taking this drug for so long. My pain was so bad, I was miserable and my quality of life sucked. I rarely went out with friends and was no fun to be around because I was in constant pain. Within just a couple of weeks after the first shot everything changed. I feel great. I had forgotten how great it is to not deal with pain everyday. My doctor started me on the 30 day shot to ensure I could manage the side effects. I waited exactly 30 days to get the 2nd shot and 2 to 3 days before the shot I started to experience pain and other symptoms associated with my endometriosis. We opted to do the 3rd shot earlier and I experienced none of my previous problems. My doctor is only keeping me on a six month treatment and I can only hope that the medicine builds up and I get the years of relief that have been reported with this medicine. I can't imagine having to go back to the way I was before. I feel like a different person. I am able to go out and have fun with my frieds, I went on vacation, and get along better with my family. I consider it my miracle.	F	31	60 days		9/29/2009
5	Endometriosis	I had experienced none of the side effects that was listed in the patient drug information. I guess the only side effect was pain relief!!	I have nothing bad to say about this drug other than I would like to take it more frequently. it has done wonders for my pain, and I would do it again if the doc said I could. I did it for nine months. has anyone ever done it longer? I LOVED it.	F	32	9 months		9/20/2009 Email
4	shrink fibroids before hysterectomy	minor headaches, weight gain, mild depression, fatigue, hair loss, hot flashes	lupron successfully reduced the size of my fibroids allowing my hysterectomy to be VLAH instead of abdominal. this has been fantastic - today is 6 days post surgery and i can walk 2-3 km comfortably, have 3 insignificant incisions, very little pain and could reasonably return to a desk job within another 7-14 days. being informed of the side effects is important to be able to manage through them. my doses were 1 shot/month for 3 months. last shot 2wks ago - hair loss just started - i lost hair post partem also likely related to hormonal swing so it makes sense.			3 months		9/20/2009
3	Endo, Fibroids	Moodiness, weight gain, fatigue, depression, vaginal dryness (severe), decreased libido (significant), constant spotting, abdominal cramping	I started taking this medication about 3 weeks ago. Since then, I have been spotting/bleeding nonstop - this has been the worst side effect for me so far. Some days it is lighter than others. I am always tired and very irritable. I had very little symptoms in the first few days of receiving the injection. Thankfully, my doctor also prescribed aygestin to help with the hot flashes and it has worked exceptionally well. If you are considering taking this shot, I would recommend asking the doc to prescribe something in addition to combat them. I hate the way it makes me feel most of the time and I cannot wait for the next few months to go by so I can be finished with it.	F	26	3 weeks		9/10/2009
3	Endometriosis	Hot flashes, night sweating, severe mood swings, depression.	I started taking Lupron two weeks after I had a laporatomy in December. I took six shots and told the doctor that i refused to take anymore. I was so moody and depressed that my husband was miserable, almost left me. I had to start taking Welbutrin for the mood swings after my second shot. All I did was cry. I took my last shot in May and did not get my first period since the surgery till August. AFter the period, I am having to take birth control non stop till I decide when I want to start having children. I would recommend the shots to anyone, but be sure you have a doctor that is very open with you and be there to answer your questions if you have one. If I had a question or problem, my doctor or his assistant always called me back and I did alot of research before I took the first shot. Also, I got some advice from some friends who had been on the shot and kinda knew what to look for. The only problem I am having now is that my legs and ankles started to swell in July. My left leg/foot is swelling worse than my right. I have been checked for several different things and nothing has been found. I am starting to wonder if it is a side effect for quitting the Lupron. If anyone has ever had this same problem after the last shot, please let me know.	F	28	6 months		9/10/2009 Email
3	Excessive Bleeding/Pain	Hair loss, lots of it. migraines, decrease libido, vag. dryness,	I havent had hot flashes yet, however, Ive only been taking this for one month. I still have grave concerns over what happens after the completion of this medication. And i really hope I still have hair left after this is all over with. Other than that I still think its working well.	F	37	1 months		9/8/2009
1	endometriosis	Hot flashes, Lots of hot flashes, brain-fog, severe moodiness, Extreme forgetfulness, Weight loss,	At the time was taking it -and up to a year later, I would have recommended Depo Lupron. It helped with the pain of endo. for the 1st time in my life I wasn't doubled-over in pain, and could be active! But the side effects still continue and the pain comes back. 7 years later: I'm VERY forgetfull/ memory problems, to the point it's cost me friendships and jobs. I suffer Joint pain, insomnia, occasional hot flashes, became very sensitive to chemicals and stimulants (such as caffeine, medications, food additives) With such complicated, long-term side effects and not being able to find a doctor who will look into what happened to me as a result of luron, the desperation now is worse than just the pain of endo. (plus pain/endo back too) I strongly warn against Depo Lupron!! If anyone has had similar problems with MEMORY and other long-term side affects please e-mail me with what's helped or info on Doctors who have looked into this. Thanks	F	25	6 months		9/8/2009 Email
4	endometriosis, ovarian cysts	hot flashes, depression, weight gain	Have LOVED not having a period for a few months. I've been virtually pain free! I don't know how long it will last once I'm off the drug but for now it's great. I've had 2 injections and hot flashes were the worst within the first couple of weeks after each one. But I have to say it's been worth it. The weight gain sucks, so I'm hoping to lose the 8-10 pounds over the next few months. I've been moodier than normal, but I learned to sort of "feel" when a bad mood swing was coming so I could take a few deep breaths or find another way to deal with it. In hindsight, maybe add-back therapy would have been good, but I didn't want to take any other medicine. I'm hoping this drug will buy me a chance to conceive. Aren't hot flashes and 10 pounds worth that?	F	32	4 months		9/6/2009
3	PCOS, Endo and Ovarian Cysts	Hot Flashes, Cold Flashes, Joint Pain, Fatique, and headaches	I have only been on this for about 2 weeks and i am having so much pain in my back. The first week I was bed bound for 4 days. I got my period so bad I was going threw a pad an hour it was horrable. I am hoping that the side effects start to settle. The doctor tells me that the first two weeks things get worse then your body evens out and things start to get better. I hope he is right. I was trying everything else not wanting to have this injection knowing all the side effects and my response to meds. well that time came the doctor said you have tried everything we need to do the injection now. I went for the first 3 months being a month at a time incase my body didnt respond well. then the last 3 months would be one injection. well I had the first on on 08/19/09 and I got a hot flash with in an hour of getting the thing. I will keep on trucking in hopes that the side effects settle and this will help. I can have my period 3-4 times a month and they can be very very pain full. My wishfull out come on all this will be they find some way to make me healthy. Am I wishing to high?	F	23	6 months		9/1/2009 Email
5	Endo	Hot flashes, Insomnia, Fatigue, Mood Swings	When I got the Lupron shot, I was not informed of all the side effects. It was not until after I found this website that I learned about how much it would truly effect me. Lupron has changed my everyday life, I have hot flashes, cant sleep AT ALL, I am constantly worn out, and mood swings like I have never experienced before in my life! Even though I have so many things hindering my everyday life, THE PAIN HAS STOPPED! Which makes it all worth it to me. I went to my family doctor and explained I was on the shot and he put me on Cymbalta (which helps a ton!). I would recommend this treatment, just make sure you are prepared to deal with the side effects.	F	20	5 months		8/29/2009 Email
1	pre-op for endo/pcos	hot flashes,migranes, hungry constantly, pain in my back, get angry easily(not at all like me), I feel horrible and i have not slept in 2 weeks	I am scared. My ob said she would do 3 injections of this drug before hysterectomy. I went for first inj. saw a different dr. who said 6 months is better. After the inj. I was told about the side effects!!!! She gave me horm. replacement and told me to put off surgery. Which sounded like a good idea at the time. I am now miserable!!! I have hot flashes constantly, i don't sleep, physically and emotionally exhausted, I have horrible migranes and then headaches with pain for days!!I have pain everywhere, legs,back, my hands and wrists are swollen all the time, I am bleeding, sex is painfull(has been even before inj)but is now worse, I was losing my hair on my head but that has gotten worse, my acne is out of control, I sweat so much that I am getting rashes everywhere. I am scared and dont know what to do. I just wanted to stop living with pain and I feel that the cure was worse than the disease. I just want it to be over. The doctors alway tell me "we are going to take the wait and see approach" I want to scream at them and tell them this is all ruining my life and you want to wait and see. I don't know what to do.	M	30	21 days		8/27/2009
2	Endometriosis	severe depression, extreme fatigue, cramping, heavy bleeding	So the first month has not been so great. I am extremely tired, but can't sleep. My period just showed up one day with such extreme cramping and pain that I could not even stand up..granted, not much different than before. Which is why I will continue to take the injections. I have had a laporoscopy already. Having 4 children, I would like to just have a hysterectomy, but the docs refuse to do it. My biggest thing is this...I HATE my husband. And I love my husband, so I really don't want to hate him. I just can't help it. Lupron is obviously causing some pretty severe mood swings. Hopefully I can get it under control before it causes a divorce! Email me if you are having problems too and care to talk about it :(	F	29	1 months		8/24/2009 Email
5	endometriosis and severe bleeding	The month after the first injection was bad, and I had a lot of weakness, mainly because it lengthened my period. But after the second shot, the side effects were very minimal, limited mainly to hot flashes, which are now almost non-existent.	I read the comments on this page the night before my first injection, and I cried. I almost didn't go through with it, but I am SO GLAD that I did. Lupron has been an absolute God-send. Most of the horrible side effects listed on this page are what I got when I took birth control, so I was terrified to try something else. But it has helped me SO much, and I have regained my life. I recently went from the 1 month shot to the 3 month, and my problems without Lupron are so severe, that I am taking it for ten months instead of the normal six. I'm so thankful to have it.	F	21	6 months		8/22/2009 Email
4	Fibroids	Some muscle and joint stiffness and soreness, and intermittent night hot flashes. Pain, swelling and inflammation from fibroids GONE, completely after 1.5 weeks. Noticeable fibroid shrinkage. Some insomnia as a result of the hot flashes at night after first month. Muscle and joint soreness which was helped by daily exercise. Muscle and joint side effects decreased after month 1. Hot flashes helped greatly by Estroven.	Side effects were minor compared to the pain relief from the fibroid shrinkage and slow down of heavy menstrual cycles. Huge improvement in my fibroid related symptoms. Over the counter Estroven supplement greatly helpful for night sweats. I did not get add back therapy from my doctor, but I suspect this would work more effectively than over the counter subsitutes. I was very nervous to take this medicine, but it worked! I was shocked to discover how exhausted I had been from the constant heavy periods, inflammation and pain from the fibroids. It resolves any questions in my mind regarding my planned hysterectomy later this year - it is absolutely necessary. My multiple fibroids had grown to the size of a 6 month pregnancy prior to taking the lupron. I will not hesitate to take my second 3 month dose of lupron.	F	41	3 months		8/17/2009
5	Endo Stage IV	Hot flashes, sleeplessness, weight loss	Had laparoscopy. A lot of small chocolate cysts, adhesions and scar tissue removed. I'm on Lupron for 4 to 6 months then moving to IVF. I've had 3 injections so far. Overall, I feel better than ever. I'm almost nervous to go off of it.	F	35	3 months		8/12/2009
2	breast cancer(male)	tired, no libido, some night sweating, no energy, weight gain	Was on this medication after chemo ... broke out in hives and had terrible joint pain ... Dr. took me off for 6 mo. and now we have started it back ... once an month shot ... tiredness is back and joint ache is back ... no hives as of yet... some vision related issues foggy, with some slight diziness	M	59	30 days		8/11/2009 Email
5	Fibroids and Menorrhagia	Hot Flashes(sometimes severe), Mild Joint Pain, Brain Fog (the most anoying side effect for me), Mild Acne, and I'm a bit quicker to get angry	Wow - been an interesting ride - last posted after my 2nd shot - I am the woman who was bleeding to death because of fibroids - I have had my 4th now and my fibroids shrinking so rapidly that my OBGYN thinks she can control my bleading with nothing more than Yaz after I'm done with the 6 shots. One note - after my 3rd shot I had a week where I ached all over like a really bad flu - but other than that I've had not problems that would stop me from finishing this series of shots. The brian fog is bothersome, but it comes and goes and I am still maintaining a 4.0 in my master's classes - I just have to work a bit harder at it now. So, I don't know about endo or trying to get pregant, but I can tell you that, for me, Lupron did what I was promised and I am very glad I'm taking it. Will post again at the end of this series.	F	47	4 months		8/10/2009
4	Endometriosis stage IV	Decreased Sexual Desire, Hot Flashes, Aches and Pains, Tender Breasts	My endo was discovered in 2004 and I have had lupron on and off for the last 5 years. The total time I have used lupron is around 2.5 years. I have been put back on it and the gyno has told me that I can continue to use it until decide to have children. I prefer lupron to my periods but I am becoming concerned about the long term use of the drug. A few weeks ago I noticed that my left breast nipple is very swollen/tender and my mom is concerned. In the short term, lupron may be a good pain reliever but I am concerned that the lack of hormones could be causing other problems.	F	23	3 times		8/10/2009
3	Stage IV Endometriosis	Increase in migraines, joint pain, but no other side effects other than being cold for the first time in awhile!	So far, I love it. It has helped level my mood, controls my hot flashes that I started getting after my Laparotomy, and I don't have to deal with my period now for a while. UNFORTUNATELY, the pelvic pains have not gone away, and the ovarian cysts are starting to come back less than 3 months after having them surgically removed.	F	25	2 months		8/9/2009
3	Stage IV Endometriosis	So far so good. I was told side effects may not start until second injection.	I have stage IV endo that has caused lots of physiological issues such as multiple blood filled cysts, a blocked fallopian tube, colon issues, and pain everyday when I wake up. I started going through the process of getting it removed so my husband and I can hopefully have a baby. I had a laparoscopic procedure but since endo bleeds so much and the issues with my colon and the endo growth, the dr. could only clean up one side. I'm on lupron for 5 months to slow the growth so he can hopefully clean up the other side and we can get pregnant. I've been scared to death to take this for years but I had my first injection 2 weeks ago and everything is going fine so far. I'm actually having cold flashes... kinda odd! I still have mild endo pain but I'll take that over some of the things I've read about on here any day.	F	28	2 weeks		8/1/2009 Email
4	Fibroids causing anemia	Some hot flashes. A little fatigue, complete loss of sex drive. a little foggy in the head. Weight gain maybe - not sure??	I was freaking out after the dr. prescribed this for me. Begrudgingly I took the shot. I have 2 submucosal fibroids which are about an inch around. The worst side effect I experience is the fogginess. I search and search for the right word and it never comes. The pros far outweigh the cons - this drug has turned me around to prepare for myomectomy. I was bleeding so heavily before lupron that I had to receive a transfusion. I was in and out of the ER. Long story short - I have since switched drs. New dr will do myomectomy and hysteroscopy (yeah!) Old dr. wanted to "try out" different birth control pills which do not work because fibroids have more estrogen receptors than normal uterine tissue and they feed off of those pills and just grow and grow. I am off of bcp's, and on my 2nd injection - the bleeding has stopped completely. It took a few weeks for that to happen. After the first shot, you should get a period within about a week. Mine lasted for about 4 days, tapered off to nothing. NO MORE BLEEDING!!! The reason for this is your uterus is shedding all of the extra stuff that has built up. I just had the 2nd shot last week and my stomach is now flat and I have no more fibroid pressure. I literally feel like my uterus (which was enlarged) is smaller. I really think the key is to exercise every day, take your iron, calcium and daily vitamin and REALLY watch what you eat. Yes, it is a lot of work, but I have not gained an ounce, in fact I have los	F	35	6 weeks		7/29/2009
2	Firbroid and heavy bleeding	Extreme joint & muscle pain, hot flashes, nausea, big mood swings and fatigue.	Did NOT shrink my fibroid which is the reason I was put on it...did eventually stop periods in the 3rd month. Still need surgery after all the side effects.		42	3 months		7/24/2009
3	ovarian cyst and endo	hot flashes, depression, anxiety, night sweats and bad acne break outs	i wasnt very excited to start on lupron because my mom suffered from endo and cysts so she warned me about all the crazy side effects. This is a very powerful lil shot!	F	22	3 months		7/23/2009
4	Endo and ovarian cysts	With lupron I have night sweats, joint pain and depression... other than that i am doing AMAZING!!	I was so scared to start Lupron because of all the negative things i have read about it. But for me I am not dealing with anything i cant handle. if it gives me a chance to try and have a baby before a hysterectomy is needed then i will gladly take whatever symptoms. The only things that really sucks is the joint pain and stiffness... but i try and do more stretching to help.	F	22	2 months		7/19/2009
3	prostate cancer	hot flashes, loss of libedo, fatigue, liver enzymes ( ALT, AST doubled tho I was also on simvastin. Am now working to see if it is the simvastin or the lupron that is involved	Exercise definitely helps. I had 3 mo lupron, then combined with 42 radiation treatments; will be on lupron 1 year at least. Side effects are manageable, PSA now (6 wks after radiation) ay 0.04.	M	72	7 days		7/19/2009
4	Severe Endometriosis	Hot flashes, some moodiness, decrease in sex drive, weight gain, some acne	I have been on the medication for over one month and feel great. I have gained some weight (about 3-5 lbs) and have some acne (but this may be a result of getting off of the birth control pills since I've always had bad skin). I have some hot flashes. I was so scared to take this medication after reading some patients' comments, but I truly feel fine. Hopefully this will one day give me an opportunity to have babies. HIGHLY recommnend asking your physician for add back therapy. I truly believe the pill I take once a day is the reason why my side effects are not as bad as some of the ones being experienced by others.	F	27	1 months		7/13/2009
1	Endo	severe side effects such as severe mood swings, hair loss, and loss od sex drive.		F	27	5 months		7/12/2009 Email
4	Fibroids, heavy bleeding	Hot flashes, pressure in my head, depression, menstrual cramps, sweating, increased sex drive, vaginal dryness, forgetfulness	I never had menstrual cramps before until I took this medicine. Sometimes I would be in intense pain, which would last for about 10 minutes. I haven't had a cycle for the last 2 1/2 months, which is good cause I had them twice a month before Lupron. The pressure in my head and dizzyness was almost unbearable, but has gone a way. I'm in my third month and some of the side effects are starting to ware off. I'm glad I took the medicine despite the side effects since it gave me a three month break from my heavy twice a month cycle. Hopefully I won't need surgery after the three months is up...	F	27	3 months		7/8/2009
1	Huge Cervical Fibroid	Non-stop migraine headache from time of injection, continual bleeding/spotting, acute constipation, severe acne, severe increase in bulk symptoms, joint pain, forgetfulness, foggy-brained, severe mood swings (extreme anger/suicidal depression - NOT KIDDING), itchy skin, hot flashes, loss of maternal instinct (DID NOT SHRINK MY FIBROID - Don't let your GYN dupe you! Cost/Benefit analysis? Just say NO.)	DO NOT TAKE THIS DRUG.	F	31	4 weeks		7/7/2009
5	Precocious Puberty	Has nearly stopped precocious puberty side effects.	My 10-year-old daughter has had Lupron injections for 23 months now. (She was cocaine exposed in-utero, which we believe is the primary cause of the precocious puberty.) Her dosage has increased 3 times over the 2 years. Her developing breasts disappeared, her extreme mood swings are dramatically reduced, PMS symptoms gone, migraines gone, she's gained 5 inches in height, and her bone age is now nearly her real age (not 50% older). On the other end of the spectrum, I'm just finishing menopause (no Lupron) a little younger than the average woman, and am experiencing much of the symptoms many women who hate the Lupron are experiencing. Huge hormone changes can be a nightmare, whether drug or nature induced.	F	10	2 years		6/29/2009
1	Endo	Feeling out of it,Dizzy, Headaches, joint aches, depression, moody, acne.. did I say depression??	I am going back to my painful cycles, these side effects are worse to me because they are constant, not 2 weeks out of the month..	F	28	1 months		6/22/2009 Email
5	Endomitriosis	No side effects. I felt great the entire time.	I felt great when I was on Lupron. I didn't have to worry about pain, cycles, or blood. I would suggest the add back therapy to help even out the hormones.	F	21	12 months		6/19/2009
4	reduce estrogen for more growth	HOT FLASHES!!!	im very pleased with this medicine. without lupron my adult height would have been 4'5 but thanks to lupron i am now 4'11.75 which is taller than i could have ever hoped for. the hot flashes were a pain but it was worth it.	F	15	2.5 years		6/17/2009
3	prostate cancer	Hot flashes, major memory loss, severe depression, anger, breast development, lethargy, no motivation to work	I trust my doctor that it's the right treatment, but I hate the side effects and can't wait for the treatment to be over. I've been taking it for 2 years; 3 years to go. I've had radiation and brachytherapy. At diagnosis, my PSA was 25 and my Gleason score was 9. PSA now 0.03.	M	58	2 years		6/15/2009 Email
3	endo	hot flashes,night sweats, mood swings, hair loss, memory loss, headaches, joint/muscle pain, loss of sexual interest, extreme vaginal dryness.	My last injection was May 1 (total of 6). I am still experiencing almost all of the side effects mentioned. It has been a long, hard 6 months, but not totally unmanageable. If it reduces my endo enough to allow for pregnancy, then it was worth it.	F	32	6 months		6/15/2009
5	Stage IV endo	very mild hot flashes but those didn't start until the 2nd month. Slight decrease in sex drive. First month I was more tired than normal and had some headaches but both went away.	I was so nervous about taking Lupron and I avoided it at all costs because of what I read of other people's experiences. What I've learned is that you have to rely on your doctor and don't assume you'll have a terrible time with it. Some people do but that doesn't necessarily mean you will. I am a professional classical singer and I was worried about what it would do to me vocally and I've been fine. I'm also a triathlete and I was terrified of weight gain and joint pain but neither one have been a problem. The pain from the endo is GONE and that's worth so much to me. I have it everywhere - on my colon, small intestines, in my left ovary, you name it. The pain was making my energy worse than the Lupron. I told my husband that if I could stay on it I would. After my 3rd shot next week, I'll have one to go. Do your research on the drug and find a doctor you trust.	F	36	2 months		6/11/2009 Email
4	endometriosis - severe pain	some moodiness, swollen breasts but that's subsided, fatigue, a few hot flashes	I have every intention of continuing my Lupron treatment. It is definitely working. I'm 44 and my first shot put me into immediate medical menopause. . .yeah! I have a few endo twinges but that's about it. This medication is a God send for me.	F	44	1 months		6/10/2009
5	Fibroids and Menorrhagia	A couple of mild hot flashes, and some moodiness (a bit quicker to cry at a sad movie, but nothing severe) I also have a bit of joint pain, but I'm not sure if this is directly related to the shot or is because I've been getting up and walking more since I'm not as horribly anemic.	I was terrified of starting this treatment because of all the negative reports I keep seeting, but I am so glad I did. Before lupron I was bleeding to death with 18 out of 28 day menstral cycles. Since I started lupron, I've only had one cycle, and it was mild compaired to what I used to have to deal with. I will come back and post again if I have start to have problems, for for now, this has been a life-saver.	F	47	2 months		5/29/2009
4	Severe Endometriosis	I have gained weight and I hate it but I have no periods which I love. I am slowly but surely getting my sex drive back. My breast are huge but beautiful. :-) Seriously, I've been on Lupron for about 2 years. I had a serious talk with my GYN regarding how long I can be on this medication and what alternatives that I have. You see I have BiPolar I and a Seizure Disorder so a Dr. is not treating just one issue he/she is treating a co-morbidities. Before when I was not on the Lupron and I was on my cycle there were a couple of times or more than a few times than a few times I went into a manic state so the Lupron right now is giving me a repreve. Right now a hysterectomy is not an option.	I've been doing pretty well for the last two years all things considered. I don't want to stay on Lupron forever but I don't want to go back to having my cycle either which turned me into my manic state which in one case landed me in the psych ward because of my bipolar and endo combined. So you see each person is different and you can only do what's best for you. :-)	F	36	2 years		5/29/2009
5	Severe Endo and Tumor in uterus	I have NOT had a horrible experience with Lupron, I was so scared by all the info on here about all the side effects. I have just started my 7th month of treatment, I am doing 1 year of 3 month injectons. First few weeks were rough but everything was fine after that. I have a few hotflashes when I get the shots but they go away. I do have a lot of nightsweats, usually 2 or 3 a night, I also have lost my libido, thank god for some helpers in that area! I also take the add back and when I forget for a few days...you dont want to be around to see what happens! I did have a lot of joint pain for the first month, I could barely walk up the stairs. I started taking 1 tylenol arthritis for it and I am totally fine now. Some of the crummier side effects are the loss of sex drive and the vaginal dryness, and the weight gain. I just feel like Im a lardo all the time. But I am very happy I have taken this drug! Everyone reacts different, please talk to you Dr. and get all the details before sayi	My Dr. found a very large mass in my uterus and when he went in to take it out he also found that I had severe Endo. He wanted to do a hysterctomy right then, thank god my husband told him no way! ( we do not have children yet)after the Laproscope I started the Lupron Depot to help with the endo and to shrink the tumor so they can take it out.	F	29	7 months		5/27/2009 Email
1	OVARIAN CYSTS	Gnawing bone/joint pain, osteoporosis, osteoarthritis in all paired joint, neuropathy, blood disorder, autoimmune disorder	I wouldn't recommend this drug to my worst enemy. If you would like this drug taken off the market or at least its use limited, please go to: WWW.Petitions2congress Letters will be sent to your Congressmen and President Obama	F	38	2 months		5/27/2009
1	Endo	Weight gain, could not control emotions, persistant bleeding, loss of memory, Severe bone and muscle pain, pituity gland shut down, within one year of last injection diagnosed with autoimmune disorder	Please, do yourself a favor, don't take this drug no matter how wonderful you think your GYN is. Taking this was the worst thing I could have done to myself. 4 years later and I still have problems brought on by this drug. Please, don't be fooled by your GYN like I was!! Two, 3 month injections..	F	44	6 months		5/18/2009
2	endo	constant headaches,dizzy,very tired,acne and depression	i feel awful. i want this to be over. i have had 2 surgeries and my only other option was to get a hysterectomy!i'm supposed to to stay on the shot for 9 months but i don't know if i can last that long! why me???	F	34	4 months		5/15/2009 Email
5	Stage III Endometriosis	I had some hot flashing and night sweats, but it was sooo worth it! I was so scared to go on Lupron b/c of all of the horror stories I hear, but it was awesome. I am also very sensitive to hormones and can barely tolerate the moodiness from birth control. Lupron was actually better from me than birth control. I experienced less moodiness. I can't say enough good about this drug. Don't let people scare you. Everyone is different, but as a rule in general, people that are getting along with a medication aren't going to take the time to review it on the website. Go for it!		F	28	6 months		5/14/2009
3	Stage 4 Endo	Hot flashes, night sweats, mood swings, anxiety, depression, edema	As my doctor warned my husband after I had lap surgery, Lupron can cause mood swings bad enough to cause a divorce in a seemingly happy marriage... THIS IS COMPLETELY TRUE. The mood swings I have are so sudden and drastic, it's like being a different person for 6 months. I neither recommend or caution against this medication, but you have to be prepared for what is to come! Please email me if you are experiencing these same problems, I would love to correspond with someone who understands!	F	27	3 months		5/13/2009 Email
3	endometriosis	hot flashes & weight gain, no periods. Uncontrollable appetite.	Pain was relieved somewhat after a few weeks. Hot flashes were almost unbearable. My last shot was two months ago and the hot flashes are now gone and the pain is back. I'm hopeful that the 10 pounds goes away soon as well but I'm not holding my breath.	F	32	2 months		5/13/2009
3	Endometriosis	Long-term side effects after treatment had worn off. Lupron did what it was supposed to, I got all of the expected side effects which were bearable. But the week the Lupron should have been out of my body, I got severe symptoms that have lasted almost a year.	The side effects while I was on Lupron were really not that bad because I had read up on it and knew what to expect. The add-back therapy with it helped tremendously! The only thing that affected my life significantly was short-term memory loss and now a whole list of symptoms that seem to have been caused by the treatment. If anyone has had long lasting anxiety, depression, palpitations, dizziness, fainting,etc. after finishing treatment PLEASE e-mail me. It has to be from this shot.	F	22	7 months		5/7/2009 Email
4	Stage IV Endometriosis	Hot Flashes, Insomnia, weight gain in the belly - but not bad at all considering the mess I was in before.	I feel women should really do their homework and decide what is best for YOU. The side effects for me are really not bad at all and considering I had a 5 hour surgery to remove huge ovarian cysts and had such horrible endometriosis they had to remove my appendix and I had a 9 day stay in the hospital....follow up ultrasounds have shown that the Lupron has been effective in the treatment so I am thankful!! :)	F	36	3 months		5/5/2009

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Average rating for drug: 2.8. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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