WELLBUTRIN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (1230 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

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More on WELLBUTRIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Major Depression Started with 150 XR generic to "augment" Prozac (40-60 mg daily for ~2 yrs), not exactly sure why I was even looking for a boost -- undergoing significant extra stress, in summary. I asked to increase to 300 mg within a week or two ... again, not quite sure why. To intensify its expected "feel good" effect, I guess. Knowing it is a dopamine enhancer, I was aware it would stimulate pleasure centers formerly activated by drugs and alcohol. In short, it does indeed appear to be a faux cocaine, although the high wasn't near even the rather lame high of cocaine yet the adverse effects were strikingly similar if not yet out and out as dangerous. Within two weeks of 300 mg XR, I quit taking Prozac because I believed it to be the cause of my fatigue. I figured the Buprion would keep my mood & energy up on its own. DEAD WRONG. I became reactive, aggressive, angry, lashing out, having rageful outbursts...yet i attributed this to my underlying depression itself and stayed the course believing the drug would help me. Excruciating abdominal pain one day. Vision beginning to experience faint tracers, which is terrifying to me (WTF!!). PRONOUNCED short-term memory loss! Immediately forgetting what I was just about to do or had just done (no thank you!!!). WORD CONFUSION -- I meant to say one word and a random word popping in my mind mid-speech would come out instead (loss of control of one's speech -- GREAT!!!!). CRYING OUTBURSTS began almost immediately even on the good to feel your feelings, but...). As so many others have reported, my DEPRESSION WORSENED. My psych doc (NP) said this was a possibility if I stopped taking the Prozac. **EXTREME** FATIGUE, IMMOBILITY ("asthenia") just about THE WORST effect of all. Oh but wait--then there was the creeping DESPAIR, HOPELESSNESS, BLEAKNESS AND BORDERLINE SUICIDALITY THE LIKES OF WHICH I'D NEVER EXPERIENCED BEFORE. AND MASSIVELY ACHING ALL OVER. NEVER ACTUALLY FELT "UP," JUST INCREASINGLY DOWN, DOWN, DOWN. I, like many ppl on these sites, quit cold turkey today. Fearing withdrawal, the only difference I've seen, besides no change yet in the OVERWHELMING FATIGUE, is a RETURN TO BETTER MOOD AND RESTORED CLARITY. I don't even want to return to Prozac. This was such a HORRENDOUS RE-LIVING OF WORST DEPRESSIVE OVERTAKE that I am determined to restore myself with CARE & RECOVERY. That entails taking the mind/body/soul REST that I need, tending to my FEELINGS, and dropping burdens and stressors. More healthful eating & exercise will come as self-love grows to _naturally_ motivate me to further my sense of well being. I will keep the SSRI on the shelf in the event the engulfing phantom of DEPRESSIVE mood disorder returns, but I am going to cope with my own devices first vs. coping with the comparable roller coaster of medicating this condition. It has been eye-opening and VALIDATING to read everyone's testimonies. WE ARE NOT ALONE. SHARED STRENGTH & COMPASSION. BLESS. F 44 1 months
350 XR gen
7/13/2015
Email
 1  smoking cessation After taking medication for approximately 2 weeks experienced severe itching, redness and welts I'm on a Medrol Dose Pack now, but still have severe itching. I'd like to know what is the main ingredient in this medication that I'm allergic to. F 44 2 times
5/10/2009
Email
 1  depression extreme anxiety and depression. Buzzing sound in my head that would not let me sleep, had to keep tv on all night to keep the buzzing at bay! Went to another doc and he say wellbutrin was too stimulating for me. He said my problem is general anxiety which leads to depression when your brain has had enough. He put me on Zoloft and it has done wonders. Still get anxious from time to time but nothing like the old days! M 44 7 days
1X day
3/29/2010
 1  depression/anxiety My doctor perscribed wellbutrin for me as an add on to my regular SSRI 7 weeks ago. I was just starting to feel some good results with a more stable, mellow mood. Until last tuesday when, while having an important meeting with some colleagues, I had a grand mal seizure lasting from one to two minutes. I have never had a seizure before. After going to the hospital and having a complete work-up it has been decided that it was the wellbutrin that caused the seizure. I smashed my face up, bit my tounge so hard that I cannot speak! It was a terrifying experience and I have since learned that it is not all that uncommon especially with people taking the generic extended release. I was happy with the results I was getting with wellbutrin until the seizure of corse. I would like to hear from others who have had seizures from this drug. How long were you on it before you had a seizure and did you ever have another seizure after the first one? F 44 2 months
150mg/day
3/29/2012
Email
 1  depression / anxiety To whomever tried to email me regading my 3/29/12 post (I had a grand mal seizure on this stuff), please resend the email as I lost it before I could get it to open! F 44
100 1X day
4/17/2012
Email
 1  smoking cessation Rage, Anger, Weight loss, Sleep depravation I have taken wellbutrin for almost 2 weeks now. The first few days I thought it was great, I actually didn't want to smoke, but then day 4 I started smoking like I always have, and my mind became very cloudy, at times I couldn't understand what people were saying to me, I am normally a very easy going guy, but this drug made me feel so much anger that I actually felt like beating someone up, that has never happened to me before, I called my doctor and he said come off the drug immediately, serious fits of rage and anger are the worst side effects in some people for this drug, and should cease taking it if it continues.. M 44 13 days
3/12/2007
Email
 1  Bipolar 2 severe anxiety and depres Smoking slowed down, loss of appetite but no weight loss. It worked well, for a while... Then I hit a deep depression in September. My doctor and I talked about it and we decided to try going up on the dosage, from 150mg once a day to twice a day. I had a nervous breakdown and wanted to commit suicide in less than a week and ended up in the psych hospital. I was weaned off of it and put on geodon. I'm responding extremely well to geodon and feel great. Wellbutrin almost killed me. F 44 1 years
150mg 2X day
11/11/2020
Email
 5  stop smoking, mild depression horrible headaches and increased heart rate requiring me to dig out my old beta blockers from a previous illness. beta blockers kept my heart rate in line. My main objective is to stop smoking. I am still smoking and show no signs of losing intrest yet. I am hopeful it is still too soon on this. However, I have mild depression due to several life situations that I have just kind of plugged along with and tried to cowboy up about. I decided it was time to drop the cigarrets and the depression and wellbutrin seemed like the logical choice. I am using 150mg once a day and let me tell you, the difference it has made in just 4 short days is miraculous. I feel like my old self already. I hope it lasts because going back to the darkness will be lousy after finding so much improvement. Now if it will just help me kick the cig habit, then it really is a miracle drug. I really like it. I have never taken an anti-depressant before so I have nothing to compare to. F 45 4 days
12/8/2006
 5  Depression, smoking cessation Absolutely HORRIBLE taste in my mouth, most pronounced after drinking coffee or smoking a cigarette. Rapid heartbeat, hyperactivity, insomnia - these three may be the result of improper usage. Doctor neglected to tell me to take pills 8 hrs apart - I've been taking them together. BIG mistake and possibly quite dangerous according to the PDR. Glad I found out now! Well, I don't have the crying marathons any more. I have more energy. Anger management has improved, no more sudden outbursts of irrational rage. Appetite has gone back to normal whereas while depressed I ate all the time - food was my comfort source. Though my doctor said it would be 5-6 wks before I noticed improvement, I'm noticing changes now in my 3rd week. Hopefully the side effects will go away. For now I don't mind the bad taste in the mouth as it's making me smoke less and NOT want a cigarette. Improvement of concentration, focus, and memory is minimal at this point but it's early yet. I would recommend to everyone to read the drug disclosure statement given by the pharmacy carefully and thoroughly. I skimmed it and missed dosing info. Had I paid more attention, I would have realized my doctor's oversight sooner. I'm lucky it didn't result in heart failure, seizures etc. PLEASE READ THE INFO. F 45 3 weeks
10/10/2006
 5  depression anxiety For the first week or so, I was very nauseous. I also had very vivid dreams. I actually enjoyed the vivid dreams since I was taking it for Depression due to the death of my son, I was dreaming about him.. That was actually a nice side effect I was put on Lexapro after my son passed away. That made me really not care about anything, including the fact that I had put on 40 pounds in 1 year. I weaned myself off the Lexapro slowly after 1 1/2 years on it. I realized after a few months that I was still so depressed over my son. I asked the DR to put me on something that would not have a side effect of weight gain. I have been very happy with the Wellbutrin. I have lost some weight and the Sadness is less but I know it will never go away. I feel I can focus more. F 45 45 days
4/6/2007
 5  Pain - mild depression etc Insomnia slight agitation roller coaster much worse with caffeine. Only two weeks in but feeling better already along with getting a taste of what the full effect will feel like - this is an awesome product if you do it right. I highly recommend taking it alone and no alcohol and very little if any caffeine. Many many drugs interact and directly reduce its efficacy. Also it takes quite some time to feel better and work through the side effects which minimize or go away altogether. Stick it out , you will not be disappointed. M 45 2 weeks
150 x 2 D
3/17/2012
Email
 5  Clinical severe depression The best side effect of all: relief from clinical major double depression (severe depression and dysthymia). An activating drug, which was perfect for me as I was previously too tired to do anything. After I started taking it, I actually wanted to get out of the house. It was my own personal miracle. I pay cold hard cash for brand name as I believe generic in this drug is not as effective, and I have no interest in risking it. It's the only drug that has worked for me, and I've felt normal for years. But I will never, ever forget the absolute and complete dreadful misery of depression. I don't ever want to go back to feeling that way again, and I will never take this medication for granted. Thank god for Wellbutrin. F 45 12 years
450 1X day
8/31/2012
Email
 5  for perimenopausal depression, etc UPDATE: It has been a month, and I love this drug! The BRAND has caused no allergic reaction. The insomnia has gotten far better as well. F 45
100 1X day
11/1/2010
Patient History
 5  depression none at all Energizes me and makes me not be depressed. I tried the SR and XL versions and they made me feel terrible--anxious, nauseous, and just "not with it." Now on just plain Wellbutrin 100 mg. in the a.m. and feeling great. No more depression and lots of self confidence. It didn't help with anxiety though. Taking a small dose of antianxiety med in the evening. This combo works great for me. F 45 1 years
8/26/2009
 5  Bipolar -more depressed, less manic Increased orgasm ability. No negative side effects. Am a non-smoker. Was briefly hospitalized for thoughts of suicide last month. Was never on meds. Now take 100mg Wellbutrin am and 500mg Depakote pm. Tried Zoloft and Cellexa with bad side effects (severe headache and nausea respectively.) Even at this small dose I am much better. I only weigh 100 lbs, so I don't need much. Have finally had orgasm with partner after 2 years due to this med. Wellbutrin is a miracle drug! Will never go off it. F 45 3 weeks
1/3/2009
 5  fatigue none i love it, its a miracle drug. F 45 1 months
7/20/2004
Email
 4  depression/anxiety extreme nausea, which went away after about one week, excessive sweating, which is still happening, and weepiness. My libido seems to be getting back to normal after being on Paxil for about nine years. I switched from Paxil after about nine years due to sexual side effects and weight gain. Hoping I will see some good side effects after these inconvenient ones pass. I am sweating so much though, that I am carrying an extra bra to work! F 45 14 days
3/28/2007
 4  depression, anxiety, Dry mouth, yucky taste,initial weight loss and less drinking. This is my second year on it and I just went up from 150 a day to 200 a day. I'm not sure if Wellbutrin is the cause but I've had intense leg pains at night since my dosage was increased. Has anyone else experienced this? F 45 1 years
1/26/2009
 4  SAD None Every winter I experience SAD living in Chicago. This year was unbearable. I was highly unmotivated, in a fog, unproductive just doing what absolutely needed to be done. In addition I was highly irritable. We're talking pissed at the grocery store clerk for no reason. I was craving and drinking 1-2 glasses of wine anytime after 5 pm. In the short time I have been taking, all areas have improved. I am closing more deals at work, nicer with my kids and spouse and generally feeling more grateful for this short life. I still occasionally get irritated but who doesn't. My dr just upped the dosage to 300 because he said 150 is very little. I will try to see if irritability completely dissipates with out side effects but if not I am planning on continuing at the 150 dose. F 45 2 months
150
2/25/2015
 4  Depression hot flashes, thought I was beginning to go through the change until I read the studies, night sweats, insomnia but not as tired/lethargic as previously, decreased apetite I am also on Lexapro and have been for many years. I thought I was not getting any benefit anymore (Lexapro poop out) The same thing happened after years on Zoloft. My doctor suggested adding Wellbutrin XR (generic). So far so good but since I have only been taking it for 2 weeks I'm still in the wait and see stage F 45 2 weeks
300mg 1X day
10/2/2010
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