SINEMET Reviews (LEVODOPA; CARBIDOPA)Average Rating: 2.5 (87 Ratings)Filter ResultsCompare SINEMET with similar:
Type: Rx Drug
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Results are sorted by Gender males first. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on SINEMET: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR SINEMET | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | Restless Leg Syndrome | Works wonders. After 2 years use, I now need two tablets instead of one, but no noticeable side effects. | M | 63 | 2 years | 1/29/2007 | 5 | Young Onset Parkinson's | Occasional dyskenesia if I dont dose correctly, ON/OFF periods | Saved my life! I medically retired at 33 from the Air Force. SINEMET is the medicine that helped, all the agonists had extreme side effects. SINEMET has allowed me to go back to work as an IT specialist. | M | 38 | 5 years | 1/11/2005 | 4 | Parkinsons Disease | Nausea, wearing off and wearing on discomfort, lack of motivation | If PD is present it works wonders, shame that there are side effects with long term use | M | 55 | 20 months | 8/31/2004 | 4 | Parkinson's | Initial nausea, burning and bad taste in mouth, and some trouble sleeping. | HANG IN THERE if you can. Sinemet did improve my PD symptoms but it did take about six long weeks to get passed the nausea and some of the other side effects...I had to give it (Sinemet) a chance and just put up with the bothersome side effects for a while. I did find that taking the pills with a full glass of warm water and not taking them on an empty stomach did help. Sugar-free hard candy also helped with the bad taste in my mouth. Currently, I am in the process of adjusting the dose and adding an agonist (Requip) at bed time to find the right combination and dosages to best address my symptoms. Summarily, response to this medication appears to be variable just like the symptoms of PD. | M | 62 | 5 months | 4/6/2009 | 4 | Pd | Confusion joint pain sleepless constipation greed impulsive | M | 55 | 2 years 25/100 | 1/3/2014 | 4 | ideopathc young onset parkinsons | start of dose dyskinesia and severe dyskinesia at end of dose (evenings)Very tired during day,lack of energy and self motivation.. have now developed a new symptom -over-breathing whilst having evening dyskenesia which leaves me breathless till I fall asleep.I presume it is from all the exertion and ballistic movements. | i still have relatively good results from my sinemet (high dose)I have a lot of freezing episodes now lately even if i am "on"I know there is no way I can reduce my dose because if I start fluctuating, I will experience these horrible dyskinesia's. I know most pd patients that suffer from dyskinesia gets the peak dose variant-I get the diphasic type which come in effect when my brain reaches certain (low) levels of levadopa (dopamine).There is no effective treatment yet and it leaves most specialists puzzled,The doctors always say to come down with the dose, but it is wrong to compare this type of dyskinesia with "peak dose" dyskinesia as it seems to work just the other way around. amantadine also has no effect on this type of dyskinesia.Lowering the dose of sinemet is also disastrous because then I experience more fluctuations and dyskinesias.My Doctor once made the following remark." we'll have to come way down with your dose,you don't need to be Tarzan the whole day"My word! As I still contribute to the household as a whole and my sinemet still carries me through the day albeit a high dose,I cannot go into total freeze- up, or suffer with the low dose fluctuations/dyskinesias I am afraid adding agonist medications will just prolong the dyskinesia when I take my last dose of sinemet in the evening. I know there is some research going on long time in finding a treatment for this side effect,and that some anti epileptic medications shows pr | M | 59 | 7 years 25/100 8X AN | 5/15/2015 | 4 | PLMD | after about a year, I have experienced heart palpitations\irregular heart beats | M | 47 | 1 years | 6/3/2006 | 4 | Sinemet | weight gain, sleeping problems | Works well for me so far. I also take Mirapex so don't know if Sinemet is helping or not, but with the minimal side effects, I will continue taking it. | M | 59 | 6 months 25/100 mg. 3X day | 2/19/2011 | 4 | Parkinson's | Difficulty walking right leg leans toward left leg. Had left hip replacement and is doing well. | Just lately last few days started taking flexerell and also celebrex foir back spasms. | M | 77 | 2 years 100mg 3x d | 9/18/2015 | 4 | Parkinsons | Nausea, insomonia, | M | 49 | 4 years 25/250 mg | 3/22/2017 | 3 | Parkinsons | My husband had major side effects: hallucinations, paranoia, increased anxiety, screaming fits, throwing himself out of bed..it was terrible. But after awhile, seemed to adjust. He began with it 3 times a day, but is now up to 7. I think I read that the max that should be given is 8 which he is quickly approaching. | He takes an anti psychotic drug (Seroquel) and antidepressant (Prozac) in addition to the Sinemet which seemed to eliminate hallucinations etc..Sinemet seemed to decrease drooling and mask like facial appearance. His hand writing is still extremely small, his voice very soft. He is in a wheelchair and unable to walk. My understanding is that he is in the Advanced stage of Parkinson's. Recently, he has increasing dystonia on the left side (leaning), and left foot twisting. | M | 84 | 7 years 25/100 7X day | 7/10/2015 | 3 | parkinson | M | 59 | 2 years 25/100mg 3X day | 9/5/2012 | 3 | Parkinson's Disease | Extension of fingers; cramping of fingers; headache; dizziness; tightness in shoulders. | Tricky to dose; hard to distinguish the side effects from the disease it treats. When dosed properly, it's wonderful, making me able to be almost "cured." | M | 64 | 3 years | 9/25/2006 | 3 | parkinsons | terrible stomach discomfort and constipation | as far as i'm concerned it does what is expected providing.relief of strong tremor and a somewhat sense of well being.However the accompaning stomach discomfort more than makes up for the good.Kindly respond if you've experienced the same discomfort. | M | 73 | 1.6 years | 11/24/2006 | 3 | Parkensons | Severe start of dose and end of dose dyskinesias | Makes me very tired during the day | M | 59 | 8 years 900mg p/d | 4/4/2015 | 3 | Diagnosed PD | Extreme daily sweating and chills as if I had a fever which I don't | M | 68 | 10 months 25--100. 3 | 1/21/2015 | 3 | Depression/Anxiety/OCD | a weird burny feeling in my chest, worsening of OCD symptoms, a little bit more anxiety than before, | i take half of a yellow 100/25 pill ........overall, this medicine can help a little bit or a lot with the depression, but it makes anxiety and OCD worse, obviously. if u have no other options this can help with depression, but u should take it with an MAO-B inhibitor (such as selegiline or rasagiline) to prevent possible neurotoxic damage caused by the dopamine matabolism in the brain. | M | 18 | 2 days | 10/6/2009 | 3 | Parkinsonism | none | Have been taking it for about 3 months. Seems to have reduced tremor and improved speed of movement | M | 77 | 3 months | 3/29/2002 | 3 | I have MSA with Parkinsons symptoms | Hallucinations and after 10 years my front teeth are cracking. | Sinemet helped with movement. I take 1/2 a pill twice a day. | M | 73 | 10 years | 9/7/2009 | 3 | Parkinson's disease | Sleepiness, dyskinesia, mental slowness | For those recently diagnosed with PD: take advantage of all you can - you'll never feel better than you do now. I was diagnosed with PD in 2001. I've taken Sinemet for 7 years. After 6 years of relatively good control of my PD symptoms on Sinemet, I began to have dyskinesias or unintentional or dystonic movements and spasms. My co-workers thought I was drunk. But inside I was a mass of clenched muscles, especially in the jaw, neck, upper body. Sinemet kept me going rather smoothly for 6 years, but now I walk a tightrope between PD symptoms and side-effects. Sinemet also slows me down mentally, like I was drugged. (Laugh - I am!) These days I take a nap almost every day, out of necessity, in order to get through a work day, which for me is the evening shift. I'm a musician. | M | 55 | 7 years | 7/17/2008 |