SINEMET Reviews (LEVODOPA; CARBIDOPA)

Average Rating: 2.5 (87 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5


RATING  REASONSIDE EFFECTS FOR SINEMETCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  parkinsons wearing off F 10 months
10/2/2004
 2  Parkinson disease. 2 days
200 3X day
11/8/2016
 2  undiagnosable progressive paralysis upset stomach, vomiting after dosage, serious agitation, inability to listen, hear's a couple words of sentence, jumps to conclusion (sometimes very unrealistic), initial energy boost, drops a couple hrs later, frequent severe fatigue. This chld doesn't have parkinson's, dosage times must be very carefully monitored, any deviation creates serious problems in physical and mental well being. a snack (not a meal) must be given 15-20 min after meds or vomiting will occur. Initially it did seem to help with fine motor control but I now believe the side effects are not worth it. She can't go out and play much when she gets sick 3 times a day. The agitation during the drop effects everyone in the home. She has always had trouble sleeping it is now much worse F 8 5 months
8/25/2008
Email
 3  INVOLENTRY LEGS SPASMS DIZZINESS, VOMITING FOR A SHORT PERIOD. LOSS OF APPETITE. HAS HELPED LEG MOVEMENT SETTLE DOWN F 16 5 months
4/18/2004
 3  Depression/Anxiety/OCD a weird burny feeling in my chest, worsening of OCD symptoms, a little bit more anxiety than before, i take half of a yellow 100/25 pill ........overall, this medicine can help a little bit or a lot with the depression, but it makes anxiety and OCD worse, obviously. if u have no other options this can help with depression, but u should take it with an MAO-B inhibitor (such as selegiline or rasagiline) to prevent possible neurotoxic damage caused by the dopamine matabolism in the brain. M 18 2 days
10/6/2009
 1  help with dystonia of left foot Tingling in my head and irratic heartbeat. It makes me feel like I'm going to have a seizure and or heart attack. F 23 2 days
10mg 1X day
10/18/2010
Email
 4  Young Onset Parkinson's Brief stomach upset when taken in the morning. Dosing is tricky. Restless when taken too much; very evident when it wears off. Flatulence (yuck), daytime sleepiness, nighttime insomnia, and some memory issues. I started tremoring at age 27. I was diagnosed with essential tremor for a long time. My symptoms got progressively worse until it became difficult to function. After suggesting PD to my doctor for over a year, I finally got properly diagnosed. Sinemet has made my life so much better. I'd take the side effects over the inability to write, walk, and engage in normal life activities ANY DAY! F 35 4 months
7/2/2008
 5  dopa responsive (partial) dystonia Nausea and feeling rotten when first taking in morning, coming off effect, however if you take them correctly and with having something to eat (do not take on empty stomach) it's fine. It's been a great medicine for my family and I having a dominant gene. If we didn't have this medicine we would probably not be able to walk and be in much more terrible pain. F 37 1 years
6x62.50dai
8/22/2014
Email
 4  Young onset Parkinson's disease It is the Gold standard of PD drugs for me, it helps tremor or the lack of movement, it is a good drug but it has an = on /off phenomena after 3-6 years, to much can be as bad as not enough. Sinemet is a good medication for me, yet it is not a cure. F 37 7 years
9/28/2004
 5  Young Onset Parkinson's Occasional dyskenesia if I dont dose correctly, ON/OFF periods Saved my life! I medically retired at 33 from the Air Force. SINEMET is the medicine that helped, all the agonists had extreme side effects. SINEMET has allowed me to go back to work as an IT specialist. M 38 5 years
1/11/2005
 4  Dopamine responsive dystonia None at first as dose was increased slowly. Main side effect now are sickness and yawning fits. It stops tremor, releases tension in neck, stops twisting of foot, takes hand out of a dystonic hold. Allows me to function without my body feeling it is 100 years old. Must be taken on time with no gaps. Downside was i could never get them out the packet as they were so small. Dosage increased so now take co careldopa. F 38 2 years
8/25/2014
Email
 5  RLS Only side effect has been some nausea but have learned how to deal with that. This drug has helped me get rest at night by keeping my legs still. Highly recommend this drug for RLS. F 42 1 years
100mg
2/7/2017
 3  Restless Legs Syndrome Augmentation, daytime sleepiness, fatigue F 43 3 weeks
7/1/2004
 3  Restless Legs Syndrome Augmentation, daytime sleepiness, fatigue Gave me 4-5 hours of continuous sleep for the first couple of weeks, now it's hit and miss. F 43 3 weeks
7/1/2004
 1  Left Side Dystonia PERMANENT FOREARM AND HAND TREMOR, WHAT A NIGHTMARE!!! DO NOT TAKE THIS DRUG! EVIL DRUG!!!!!!!!!!!!!!!!!!!! M 46 3 years
6/21/2006
Email
 5  restless leg syndrome possibly night sweats, they started about the time I started the medication. The sweats could be from thyroid. Before I started taking Sinemet, I could not sleep for all the jerking motions of my legs. That problem doesn't exist with the medication. I take one every night 30 minutes before going to bed. F 47 7 years
4/30/2005
 4  PLMD after about a year, I have experienced heart palpitations\irregular heart beats M 47 1 years
6/3/2006
 3  Parkinson Pins and needles in my feet making it hard for me to walk. Feeling sick. Sleepless nights. I think that Sinemet should be taken off the market.It is clear that it is making people more ill than better. My brother took sinemet unfortunately he passed a away in February age 46 he been taking Sinemet for 10 years he always said that they were making him feel a lot worst,but he would not stop taking them because the doctor told him to take them,and my brother always said that the doctor knows whats best.He sufferd. F 47 2 years
62.5 3X day
5/18/2010
 5  Parkinson's None cause I started very slowly with much less than prescribed to allow my system to get used to it. Very good / very bad. Classical situation where a drug seems to address exactly what is going wrong in the Parkinsonian's brain and that is the diminishing capacity to make our own levodopa (which is what sinemet is). Levodopa in a healthy person is made in our bodies from basic nutrients. Levodopa, in turn, is converted to Dopamine, which in balance with two other neurotransmitters, acethylcholine and GABA, provide for smooth and controlled movement. Throwing ready-made levodopa into our bodies causes a well known pharmacological effect called F 48 7 years
6/10/2005
 4  Parkinsons Nausea, insomonia, M 49 4 years
25/250 mg
3/22/2017

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