Drug Ratings for EFUDEXAverage Rating: 3.5 (11 Ratings)
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Results are sorted by Date Rating Was Added Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 |
| RATING | REASON | SIDE EFFECTS FOR EFUDEX | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 3 | history of skin cancers on face | At dermatologist recommendation used on entire forehead and each side of my face down to the level of my ears--all in one huge treatment. As others have said, my face was a horrible mess the entire time and very painful. I am age 86. | It did what the dermatologist desired but 3 months later I am still experiencing nausea. Has anyone had a significant reaction what would indicate that efudes has a lasting effect on different parts of the body? | M | 86 | 28 days 5% 2X D | 5/28/2013 | 1 | actinic cheilosis | I was to use this drug for 2-3 weeks for actinic cheilosis, precancerous sun damage to lips. After 4 days burning started and I stopped using the cream. Lips continued to deteriorate. On day 8 they were bleeding and burning horribly. On day 10 I went to the ER. Day 11, tiny improvement. | I was to use Acetonide 0.025%, a steroid cream after the effudex treatment. But that cream also caused terrible pain and burning sensation. I look like a monster with burned, swollen lips. Only thing that helps is vaseline and soaking my lips in a bowl of warm water. Yikes. | F | 72 | 4 days 5% cream 2X D | 11/11/2012 | 3 | pre-cancer treatment | Used it on my chest for 21 days and seems to have worked great but developed a rash on my back and stomach that persists after 4 months. Using it on my arms now and the rash is getting worse and spreading to my face. I hope it's a passing thing (doctors have said it's a typical drug rash and it'll go away) 4 months is a long time so I'm hoping they're right. | I think if your sensitive, you can wind up with unpredictable side effects. It obviously enters the blood stream and can effect areas of the body that aren't targeted. Otherwise an effective treatment. | M | 60 | 21 days 5% cream 2X D | 3/29/2011 | 4 | actinic keratosis | Red skin, itching, scaling, not as bad as I had imagined. I am a month past ending treatment and still healing. I assume it worked. | I used it on both arms. I was unclear about instructions of "light film" but apparently overused it because was soon running out and my dermatologist suggested decreasing to once daily. | F | 60 | 2 weeks topical 2X D | 2/14/2011 | 1 | For Bcc | After 4 weeks many more lesions appeared on arms cleavage, breasts (started using on 4 lesions on rib cage). Stopped using efudex and many started to scab over. Once the scab fell off was bright red for 5 days then the erosion started and did not heal. Recommenced efudex use and now 4 months later the mess is unbelievable - large sores extreme pain. Doctor has told me to discontinue. | Used on my face for 4 weeks and all healed very well. | F | 65 | 120 days 30mg 2X D | 10/11/2010 | 5 | Actinic keratosis | First time use was about 25 years ago ago it was very effective at reducing frequency and amount of cryosurgies. The frequency of cryosurgies has started picking up again, so this is my second use. You can use it 2xday for 30 days and react pretty hard, or as little as 3xweek for 90 days for minimal burning. Its strong stuff and I can't imagine a woman using it "down there" like the lady rating this product a "1". But for face and arms, it was well worth the period of discomfort and unsightliness; enough so that I am doing it again. | M | 62 | 60 days thin coat 1X D | 4/26/2010 | 3 | actinic keratoses | very tight and feels like it's burning. very itchy. | hope it works! | F | 78 | 13 days 40 gm 2X D | 3/14/2010 | 5 | actinic keratosis | Does this stuff make you fatigued and sleepy? Because I started it 4 days ago and am perpetually exhausted. Otherwise, minor dryness 5 days in, and sweaty greasy feeling where applied. | I am applying morning and night all over face to eliminate actinic keratosis and possible BCC, to which I am prone. So far, no big reactions, just dryness and slight itchiness. But I am exhausted and can't seem to sleep enough, have trouble arising and functioning with fewer than 9 hours of sleep. Can a topical agent do this? After all, fluorouracil is powerful stuff. Can it get into the bloodstream? Anyone else have this happen? | F | 54 | 5 days | 10/14/2008 | 5 | BCC's and AK's | Intense burning and itching. Rash spreading into adjacent untreated areas. | I have been using Efudex 5% solution for about 10 years. It was originally prescribed to treat an area on my forehead after a BCC had been scraped off. Since then I have used it on other suspicious areas of my face, arms, and legs with great success. I recently got a new prescription for the generic 5% cream and used it on my chest for about 12 days. After I stopped the treatment, my chest started to burn. Everything I put on it just made it burn more. Then I got a rash all over my chest and on my neck in areas that weren't even treated, and nothing I tried for the itching did any good. I also used it on several areas of my face and one on my shoulder, but these areas did not have such a severe reaction. The ones on my face are almost back to normal, and I am still treating the one on my shoulder, but my chest is still very red and itchy. | F | 58 | 19 days | 9/21/2008 | 4 | skin cancer | Not exactly a side effect - it made my skin feel like I had a bad sunburn, and the area on my face where it had been applied looked like I had a blotchy sunburn. This is apparently the reaction that is expected. My doctor said "Apply it for two weeks, or as long as you can stand it. It will feel like you have a bad sunburn." | It did a pretty good job of clearing up some cancerous and pre-cancerous areas. These are usually squamous type cancer in my case. I've had twenty or so removed surgically, but the doctor thought that using Efudex would reduce the amount of surgery necessary. According to the package insert, Efudex is about 80% effective. Some of the spots cleared up by Efudex have returned in my case - about four months after using it. I applied it to my face in quadrants - two weeks per quadrant. | M | 73 | | 7/18/2008 | 5 | Essentially no side effects. The cream will cause the precancerous area to turn red and crusty. After 4 weeks of treatment I feel comfortable knowing that it has removed any potential cancer cells. | M | 57 | 30 days | 4/5/2007 |
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