MACRODANTIN Reviews (NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 2.1 (129 Ratings)

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 ANTIBACTERIALS, MISCELLANEOUS

 Type: Rx Drug

  

MACRODANTIN  (NITROFURANTOIN, MACROCRYSTALLINE):  This medication is used to treat or prevent certain urinary tract infections. This medication is an antibiotic that works by stopping the growth of bacteria. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Nitrofurantoin should not be used in children less than one month of age due to the risk of a certain blood problem (hemolytic anemia).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACRODANTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACRODANTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Urinary infection My mum had only two doses and became very poorly overnight. Couldn't put one foot in front of the other. Her mental ability waa impaired, she could't understand simple instructions and was as yellow as a split pea. We stopped medication immediately and it was 24hrs before she felt better. Never again...... F 86 1 days
30
4/29/2013
 1  mum taking it to prevent further UT Elderly mother with possible liver/lung problem too... got rash , burning palms, sever itch over whole body, blue skin and nails, diarrhea, blurred vision, confusion/delerium, mood change, persistently felt unwell, red swollen cellulitic legs, stomach discomfort, dark urine, tingling and numbness in feet, tired/weak. Neither the doctors (oncologist or GP) or pharmacist warned us of this and even when we highlighted symptoms to them, said nothing about these side effcets. Definitely would never ever use it again. F 84 10 days
2X day
5/18/2013
 1  Urinary tract infection Permanent scarring of the lungs. Can only walk a few steps and then give out of breath. This lung disease is permanent and I am now on prednisone A friend if mine also has the same lung disease caused by this antibiotic. She is now permanently on oxygen for the rest of her life. F 80 2 years
30mg
10/31/2014
 1  Complicated UTI Headache, hot, breathless, anxiety, nauseous. Lower back pain. voiding every 2 hours. Puffy eyes. F 79 2 days
100 mg 4 4X day
8/1/2022
 1  UTI After one tablet feeling sick. Day two, dizziness, drowsiness, severe gut aches, indigestion, nausea, loss of appetite. Now one week later still have gut pain and feeling tired. I would never take this drug again. I checked the net for Macrodantin Ingredients, that explains many of my side effects. E104 E171 E172 and Sodium Lauryl Sulfate. The E Additives are banned in other countries. I wish doctors warn their patients for side effects related to medications. Special as many of us do have allergies and guts sensitivity. F 76 2 days
100mg 4X day
8/28/2022
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 1  bladder infection Extreme vomiting for 3 days and no appetite for 5 days So very sick and only took 2 tabs please be very careful with this tablet Have informed my G P so I will not be prescribed this again F 75 1 days
5/3/2016
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 1  bladder infection Extreme vomiting for 3 days and no appetite for 5 days So very sick and only took 2 tabs please be very careful with this tablet Have informed my G P so I will not be prescribed this again F 75 1 days
5/3/2016
Email
 1  UTI Severe headache, hot and shivering, loss of appetite, stopped taking them after 5 doses Quite scary would not recommend taking it. F 72 1 days
50 4X day
8/31/2014
 1  Urinary Tract Infection I took ONE tablet at 15h30. At 19h30 I suddenly became ill - shivering uncontrollably as if with fever; headache; pains in legs; pains in chest. Condition worsened quickly - I was finding it very difficult to breathe. Also experienced nausea and vomiting. Cotton mouth - difficulty speaking. Sudden, heavy phlegm on chest. Was rushed to emergency where I was diagnosed as being in severe anaphalaxis. Antihistamine was administered via IV - took 2,5 hours to stabilise. Doctor also thought I had bronchitis or early pneumonia - but this is not possible as it came on extremely suddenly. Later confirmed it was caused by the drug!! My doctor was shocked at my reaction to the drug. He says in all his years of practice, he has never had a patient show signs of allergy to the drug. F 72 1 days
4X day
4/14/2010
 1  Urine infection Felt I was dying. Head one side numb couldn't walk unaided, chest tight - felt horrendous. Am so worried that any damage already sustained is irreversible. Never ever take this terrible pill. F 68 2 days
100mg 2X day
3/23/2012
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 1  UTI Within 24 hours terible pain in right side of stomach - my firt time on this drug - (usually macrobid with no problem) - so bad my doctor ordered an ultrsound of abdomen on day 4 and found nothing wrong. I ended the drug on day 5.5 not day 7 as ordered, on advice of my gyno as I was in for my annual -( drug was prescribed by my internist) It has been a week and I am sitll in pain - feeling of fullness after eating tiny amounts - next week I have to go see a gastroenterologist for a scope of the inside of my stomach if pain does not go away after being off the drug for several days. I will never take this drug again but it did stop the UTI symptoms in one day The side effects warned of are all about lung problems - the stomach pain on the right side should be investigated. I see others on this site mention right side pain. F 68 5.5 days
10/10/2009
 1  Kidney infection Nausea, dry mouth fatigue, weakness, drowsiness, blurred vision, headache, loss of appetite, loose, pale stools, severe itchiness, coughing, liver damage with some readings eleven times the normal range Three weeks after stopping the drug, having been given a different antibiotic I began to feel better but liver is not 100% better and I am still not back to full energy levels F 67 7 days
50 1X day
1/2/2014
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 4  uti The only side effects have been severe insomnia despite feeling very tired, and unusual night sweats. Also experienced floaters and flashing lights in my right eye which I attributed to posterior vitreous detachment (a common non-pathological event) but having read some of the comments now wonder if it may have been a side-effect. Eliminated acute uti quickly, experienced none of the other problems that other people have complained of, despite my allergy to penicillin and the fact that many antibiotics do cause me digestive problems. F 66 7.5 days
50 4X day
1/2/2011
 1  UTI. Enterococcus Faecalis Nausea, runny tummy, tiredness after 3 weeks of treatment - supposed to take for 6 months. Stopped taking them 3 days ago and no better. Infection dormant for now. That's it for me, no more the pharmacist took them back. Still feeling sick. F 66 1 months
100
6/14/2014
 1  UTI Do not take this drug. Beware of side effects in many people. Topix.com has much more info. Search this drug and you may be shocked M 65
100mg 1X day
1/21/2013
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Patient History
 1  UTI Severe Headache Aching legs and Arms Weakness Sickness and Nausea Dry Mouth Bad taste in mouth Lack of appitite Cold shivers Glands up in neck Sore Throat General feeling of being very unwell Do NOT take this drug It makes you ILL...very ILL F 64 4 days
30mg 4X day
6/19/2012
 4  UTI Mild headache, stomach cramps, mild pain behind eyes, mild aching in arms. Most surprising was a euphoric 'high', was in extremely good mood, I'm told this is unusual for Macrodantin but it made the other side effects easy to accept. It sorted out the UTI quickly and effectively. F 62 7 days
50mg 4X day
12/18/2012
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 1  UTI Extreme shortness of breath, wheezing and coughing after just 5 tablets I stopped taking the tablets as soon as the breathing difficulties started. I recovered in a couple of days thereafter. I wouldn't take the medication again and am trying unsweetened 100% cranberry juice now. F 62 2 days
50mg 4X day
6/30/2012
 1  UTI Difficulty breathing - even bought ashma pump. Pains in legs - thought is was associated with recent flu. Only when rash appeared on arms and legs did I suspect allergic reaction. Ceased medication 36 hours ago and all symptoms have disappeared. I have been prescribed 42 days' medication (one 50 mg capsule per day). Obviously I will never touch another such tablet. Thought I had onset of Guillaine Barre syndrome! F 62 7 days
50 MG 1X day
5/26/2010
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 1  Uti Blinding headaches . Fever. Cold sweats. Sore throat . Feeling really unwell. Have gastric reflux so had really bad indigestion and chest pains. Would never use again waiting for gp to open to change medication. F 62 3 days
50 4X day
2/2/2014
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MACRODANTIN  (NITROFURANTOIN, MACROCRYSTALLINE):  This medication is used to treat or prevent certain urinary tract infections. This medication is an antibiotic that works by stopping the growth of bacteria. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Nitrofurantoin should not be used in children less than one month of age due to the risk of a certain blood problem (hemolytic anemia).    (Sources: U.S. Centers for Medicare Services, FDA)

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