DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  to regulate my periods i was 34 years old with a very irregular period.my doc and i thought it was due to a thyroid disease. ( graves disease)so the depo was to striaghten out my hormones and allow me to be period free.i thought it was working untill i received my lab results.i was not having my period because I had gone thru the "change"so than i started taking prempo,which i still take.thru the years i always had to watch my weight.i was able to put on and take off the pounds fairly easily.in the past two years i just kept adding and unable to take off. my doc sent me to a metabulism expert.my labs came back showing i lacked all tetestrone in my body.he said this was due to the use of prempro,which decreased my eslvadiol.has anyone else gone thru this?i will start taking the tetestrone next week. F 60 30 years
10/25/2007
 1  Birth Control Weight gain. Very heavy periods. Miscarriages. Difficulty in conceiving. Facial hair. Mood swings. Pain. Would absoloutly not recommend this drug to anyone, especially those wanting to have children later. After I came off the drug, I had difficulty getting pregnant. I had no problems whatsoever, before taking depo-provera. The three times I did get pregnant, I miscarried. While on depo, my periods were very long and heavy. I spotted in between periods. My periods continued to be very long and heavy after I stopped depo. F 56 2 times
12/8/2007
 3  birth control No periods during the 10 yrs, I quit getting the shots, took over 6 mo. for period to begin. When quit drug developed cognitive loss, not thinking straight, confusion When quit getting shots after 6 months flooded old blood, 3 mo later happened again, had a D&C, followed by a Hysterectomy 2 yrs later due to cyst on ovary, no luck from D&C and laser surgery done in Dr office. It was great for birth control I was satisfied with drug for the 10 years of getting shots, I'm thinking I was a guinea pig for first women getting the shot M 55 10 years
1X O
4/28/2012
 5  Excessive bleeding with period Lot of sweating even outside F 54 2 years
2/15/2017
 1  stop bleeding from fibroids PLEASE, PLEASE, PLEASE ALL OF YOU WOMEN, REPORT THESE SIDE EFFECTS TO THE FDA. THEY ARE THE ONLY ONES WHO CAN TAKE THE HORRIABLE DRUG OFF THE MARKET!!!!!!!!!!!!! F 54 1 days
1X day
3/11/2011
 1  reduce hot flashes extreme irritation and nervousness did not reduce hot flashes F 54
1X O
5/2/2010
 5  Birth control Weight gain...maybe have poor diet. No heavy cramping cycles. Yeah. F 53 18 years
100 1X O
9/23/2010
 1  to stop bleeding from fibroids All of you that are having these horrific side effects from this drug please contact the FDA with your complaints. I called them and they didn't have any. Please, Please, contact them and let's get this drug off the market before it hurts any on else. F 53
1 shot 1X day
7/15/2010
Patient History
 1  Missed Menstrual cycle low body fat Horrific - depression, terrible headaches, hair loss, stroke like symptom, early menopause symptoms, clotting, loss of mental acuity - this stuff is POISON & should be illegal. It ended my career, my relationships & took away my sense of self. POISON - Don't take it - The effects have been permanent - over 10 years! F 51 1 days
6/18/2007
Email
 5  birth control, to end periods Weight gain is the significant one. I have other things going on but I guess we'll wait to go off the shot to see if these are caused by Depo. This was a positive experience for me but I'm anxious to go off to see if I have completed menopause. No way to tell until I discontinue the shot. I guess I'll try Essure procedure as an alternative to Depo to find out for sure where I stand with menopause. F 50 5 days
2/12/2007
Email
 5  For birth control I took it for 17 No side effects I thought it was the best birth control they ever came up with! This drug keep me active at my job due to no monthly issues. I able to be very active and worry free! I no this rare. One side effect or another. 17 years ago the shot just came out here. Friend got tubes tied I got shot. The best thing for me ever! F 50 10 years
4/12/2014
 5  birth control None that I know of F 50 10 years
4/7/2015
 5  Birth control None haven't had my periods until today. Maybe watch my weight I have been on it for 20 years but wouldn't let me enter that much! Love it. F 50 10 years
3/9/2017
 5  Birth control None. Never experienced any. I have received a Depo shot every 3 months for 23 years without any problems. Have used Depo for birth control for 23 years. The two times I stopped taking Depo I went back to my same old cycle after 3 months of discontinued use. Never had a problem, but didn't have any to begin with. My daughter and neice are all on Depo and no problems. I literally have no problems when I'm taking Depo, it's the times I don't is when I have problems. F 50 10 years
6/8/2016
Email
 4  thin uterus for polyp removal; BC takes forever to get an orgasm now, and when I do I really fall asleep, hard. Normally the doctor said she woud not precribe it for a woman my age, but I was getting "essure" fallopian tube blockers installed and needed to have polyps removed - the depo-prevara thinned the uterus lining to make the polyps easier to take out. I also wanted birth control to work right away but the essures take a few months to grow the scar tissue that causes the blockage. So the DP shot should wear off right when the essures are working. (I get a sono then to see if the tubes are blocked). My doc assured me that one shot would probably not be a problem and so far I have no headaches, no mood swings, and I feel fine otherwise. I see the slow sexual response as a temporary inconvenience. F 50 2 weeks
4/1/2006
 2  Birth control I was told that I probably ouldn't have a period with this, YAY! HOWEVER, I have been spotting since I started the shots in Jan. ALSO, I now have Menoraghia (heavy uterine bleeding) with HUGE clots. I have bled for 20 straight days. I am going to a different Dr. this Fri. If not for the constant bleeding this would be a fabulous birth control for me. F 50 6 months
150 1X O
7/1/2010
Email
 1  Endometriosis Headaches & Weight Gain No period which helped my pain from endometriosis. Bone loss Depo is Dangerous. I put my daughter on it and unfortunately she had the most serious effect after getting of it. She was on 5 yrs. Straight. Died shortly after giving birth. Stroke Brain Bleeds Inter Cranial Pressure. F 50 3 years
3/1/2020
Email
 1  Fibroids immediate forgetfulness, irrational thinking, depression, fatigue, explosive anger, mood swings, blurred vision, dizziness, constant bleeding and menopause I will NEVER, recommend this drug! It's terrible, and it should be taken off the market! I feel that additional medical research will not improve this drug! I got my first shot in January 14, 2010. An hour later, I was forgetful, paranoid, anxious & confused. I skipped my menses that month. In February, I started to spot, this then increased, bleeding more throughout the months. There were times when I passed very large dark red blood clots. I visited my doctor and explained my symptoms, as well as my altered state of mind. I asked him if there was something that he could prescribed to stop the bleeding and to counter act the drug to get it out of my system. He replied I would need a "D"- for some reason, he didn't complete the last part of his sentence, he was going to say a D & C. He changed direction and said that I would need to take another shot. I told him there was no way that I would take another shot and how in the hell could he have the audacity to recommend that I take the shot again even after I've told him what I'm been going through. He called me later on that night (feeling guilty) to check on me, he said "I don't blame you for not wanting to take another shot." I feel extreme anger, I have a drug in my system that has to wear out. April 15 - 25th I had a very heavy menstral with large dark clots. From April 26th - 29 nothing, now today, the 30th I went to the restroom and noiticed that I'm starting to spot. Well, I thought all F 49 3 months
30 mg 1X M
4/30/2010
 1  migraines due to hormones on menses heavy spotting for 4 months on depro for 4 months,I don't dare not wear a panty liner, severe depression, night sweats, loss of libido, aching joints in knees and elbows I went on depro to prevent my migranines (dr's suggestion). It did stop the migraines, I did get headaches but nothing close to the severe migraines I suffered monthly for 20 years. However, the depression started, night sweats and aching knees and elbows. Complete loss of libido. Feeling of being in a "black hole, void, like nothing matters" I am definitely going off depro, and will take back the migraines instead of this hopelessness I am expreiencing. Have the best husband, who is understanding and patience with me at this time in my life. e-mail me if you want more details. F 49 4 months
8/28/2007
 5  Birth Control I suffered from headaches but was unaware that they were related to the Depo until I stopped taking the injections, and noticed that the headaches almost completely stopped. I loved Depo. I had NO PERIODS (which was fine with me!) When I stopped taking the injections at age 44, my periods NEVER resumed. That was OK, too. But coincidentally I began feeling severe fatigue, depression, and joint pain/stiffness. My doctor tested me for everything imaginable, Lupus, Lyme Disease, Thyroid, (all negative) then gave up and diagnosed Chronic Fatigue Syndrome. My OBGYN ran a bone scan and diagnosed Osteopenia and said I was Menopausal! I think now that it is not menopause but possibly some thyroid condition induced by Depo, or lack thereof! I am still miserable 4 years later. Anyone else experience misery after quitting? F 48 8 years
3/14/2008
  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

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