Drug Ratings for ENBREL

Average Rating: 3.8 (421 Ratings)

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    New! Reviews Summary for ENBREL  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 5  rhematoid arthritis Enbrel started working within about a week. Though typically it takes longer. The injections burned but my husband did them all that helped as I can't hurt myself lol F 26 1 years
1 injectio
8/13/2014

 4  Psoriatic arthritis Dry mouth, acne and oily skin, teeth started to look bad. F 30 4 days
50 mg
8/12/2014

 5  RA Dry mouth and a small rash from injection also a little anxious F 38 3 weeks
25 mg
7/27/2014
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 1  psoriatic arthritis and psoriasis I thought this medication was supposed to help. I'm still taking it every week, no change in my joints except for my right thumb feels better. As for my psoriasis, its twice as bad as it was!! And my back is alot worse!! And I have bruises as big around as 50-cent pieces at the injection sites that take weeks to clear up!! F 57 7 months
50 mg
6/18/2014

 5  ankylosing spondylitis On the 3rd dose, I experienced injection side rashes in both legs, but the discomfort paled in comparison to the pain and suffering I had before taking the drug. Since taking the drug, I experience relief from inflamation, stiffness, and pain within 2-4 hours. My range of motion is greatly increased and all my fatigue vanishes. So far it has been a miricle drug. So despite all the scary possible side effects I was desperate to try anything. The suffering of my condition had me so depressed and in so much pain. I've suffered with mis diagnosed A.S. for over 16 years. Even if this allows me just a few good years, I'll be ok with that. M 40 3 weeks
50 1X W
6/5/2014
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 3  juvenile psoriatic arthritis weight gain, rash on face when exposed to sun F 9 6 months
1X D
5/6/2014

 1  r a After taking my first injection i was very short of breath. This continued for ten weeks. I ended up at this point going to er with a collapsed lung. I was sent straight to ICU where i almost lost my life due to enbrel. F 42 10 weeks
50mg
4/3/2014
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 4  SAPHO/ Crmo with jaw involvement The injection is super painful. The major problem I having is acute pain with pneumonia- came on sudden and docs are stumped- awaiting an antibiotic that will work. Helped my rare bone disease right away- no probs for two years. I'm so careful with germs- cant imagine how I was fine one day and full blown pneumonia the next, my rheumy was not prepared to deal with crazy "Enbrel" infections and not able to find anyone that's familiar. F 38 2 days
50 mg 1X W
2/21/2014

 2  Moderate Plaque Psoriasis I developed a serious staph G infection in my knee. My blood pressure dropped to 80/40 in the doctor's office, and for a few minutes I was so sick I thought I was dying. I came around in a few minutes, and was rushed by ambulance to the hospital, and put on IV antibiotics for 2 days until the infection cleared up. Not positive it was caused by Enbrel, but i would say likely. Cleared the psoriasis up a bit in spots, but unless it overtakes my body (currently 5 - 10% body psoriasis), I think it is too severe a gamble for me. Good luck. M 58 1 years
not sure 2X W
1/12/2014

 3  Plaque Psoriasis & Arthritis None, except for slight burning when I accidentally hit a blood vessel during injection. Once had a slight rash at injection site on thigh. I have also experienced a little dry mouth on occasion. My pain and swelling has reduced significantly, but the plaque psoriasis on my legs, feet and scalp has not cleared up as expected. In fact, my feet and legs are slightly worse, as I have now developed pustular psoriasis on those areas as well as the plaque. The plaque on my scalp seems to have decreased somewhat, but not as much as I expected. Overall, I'm not as happy as I anticipated I would be after waiting 8 months for my insurance to approve my use of the drug. F 50 4 months
50 MG 1X W
12/19/2013

 1  Psoriatic arthritis Very first day enbrel came on market my doctor called to get the injection because methotrexate wasn't working tried both pill and needle it was making me nauseated Enbrel worked good at beginning but short time after started getting infections. I was on and off for a few years until 2010 I got a serious infection that almost cost me my life all organs shut down I was on a respiratory life support with a trac. I keep getting pnomenia in and out hospital getting trac changed. I can't talk walk only dignity I have left feed myself. I can't believe a drug that's suppose to help make life easier ruined mine. But I wanted to feel good be able to go out to work pain free but now I rather suffer a little pain then of taken enbrel F 55 10 years
25 mg
12/8/2013
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 1  Rheumatoid arthritis Serious injection site reaction. Was very hopeful that enbrel would work. But I only felt worse. Joints became more swollen, more pain. Had to stop after 5 weeks. F 64 5 weeks
50 mg 1X W
11/25/2013

 1  ra I got sepsis from enbrel on May 12 2013. The ER gave me 12 hours to die or live. 103 temp and unconscious for 2 days. In fall of 2012 I asked to be taken off Enbrel & was told no. I had an arthritis nodule on my right wrist that got infected with white cells (sepsis). had two surgeries & 17 staples & 3 weeks of infusion antibiotics & 3 weeks of oral antibiotics. not able to take my arthritis meds and the only thing that is helping with RA pain is 20 mg prednisone. READ very carefully the medical insert that comes with your enbrel and ask yourself is it worth the risk. Sepsis is very painful and very dangerous. Not many people survive sepsis and I am very lucky! F 60 6 years
50 mg 1X W
11/11/2013
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 4  ra Fungal lung infection have caught every bug that comes along it helped my joints but do not like all the side effects M 65 10 years
50mg
11/5/2013
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 4  Severe plaque Psoriasis entire body Although it worked it almost cost me my life. I had flu like symtoms and became so dehydrated from vomiting my husband finally made me go to ER. It also decreases appetite. I just made it to ER and as soon as a nurse started an IV for fluids to be given and draw blood, my heart stopped. I refused to go to ER for two days because I thought I had the flu. I was then life flighted to a trauma heart center. I have been psoriasis free for 4 years now. Patients should be seen by their private medical Dr at least twice a month even if they are feeling well. The dermatologist who administered my injections never told me I should be closely monitored by my personal physician. PLEASE post these symptoms on your web site and tv advertising. It should be known. Thank you F 40 3 months
100my 2X M
10/12/2013

 5  plaque psoriasis & psoriatic arthri Very occasional injection site reaction. F 30 10 years
50 mg
9/29/2013
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 5  Rheumatoid arthritis since 1995 I have a history of headaches and have had a few doozies in the last 3 weeks but I'm not sure if its me or the Enbrel. My BP was up to 170/105 and that's unusual so I'm getting that checked out but I have had NO JOINT PAIN since I started 3 weeks ago. I can straighten my fingers which I haven't been able to do for a year. I can work out with pretty heavy weights and my grip strength is like a normal person plus no swelling the next day. I'm really excited that I've had such success and pray it will be the new norm. F 43 3 weeks
30mg
8/12/2013
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 3  Juvenile arthritis I've seen a positive improvement in my joints after taking enbrel, but this week after my fifth injection I got a horrible face rash that worsens when I go in the sun. F 14 5 weeks
7/7/2013

 1  rhumatoid arthritis After being prescribed Embrel, i decided not to take it due to all the bad side affects that i heard about. I chose to go on a trial drug test , i have been on it for 3 years now and it is to be realeased on the market here in Australia at the end of the year. USA has been realeased already. its fantastic. Blocked stuffy nose at night ( but this could also be age related ) is my only side affect. I am now on no prednisolone at all... was 20mg a day. have lost weight , no swelling or sore joints . and feel fantastic. I hope it works for everyone how its worked for me. Its also in the form of a tablet. F 49
1X D
6/18/2013

 5  Psoriasis Bruising at injection site - but only occasionally If I were reading some of the reviews without my own experience, I would be scared to death. However, this has changed my life, and as long as it works, I'll keep taking it. As for painful injection and welts, the stomach is the best to avoid this - also letting the medicine warm up to room temparture helps. I have had no problems with this medication (except for occasional bruising). The biggest pain is having to get blood work done every three months, but I'm glad my doctor stays on top of it to ensure I'm pulled off of Enbrel if there's any chance it's causing other problems. F 36 6 years
50 1X W
6/14/2013
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 5  RA no side effects This is the Best medication for my arthritis. I have tried many others one but no one has helped me so much. M 71 7 years
1X W
5/25/2013
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 1  Rheumatoid Arthritis MAJOR insomnia. Loss of appetite day after injection. Bloating. More colds/infections. Dry mouth. Major injection site reaction. Looked like a bug bite on week 2 but on week 3 looked like a bee sting reaction. 2 inch by 2 inch red inflamed area. Stayed for almost a week. One month after quitting injections muscles still have knots in them from the injection. (Quad muscles). Immediately stopped this drug. I have just started a gluten and dairy free diet to see if this will have any impact before I opt to try any more powerful Meds. God bless to all my fellow sufferers out there. F 38 3 weeks
5/14/2013

 3  RA None Worked for 5 years. At times I could go 5 weeks between shots, then take an injection when I felt stiffness coming on. Then it stopped working. M 81 5 years
50mg 1X W
5/6/2013

 1  psoriasis arthritis Gain weight, easyly caching ilnesses, Cough, Weak body, Pale skin. I used Enbrel after i tried steroids and MTX. after 2 years i tried Enbrel it worked and reduced my joint pains but side effects were crucialy reduced my daily life. then i stopped treatment M 2 years
25mg 2X W
5/4/2013

 5  RA No side effects. Completely changed my life--I would be in a wheelchair by now w/o Enbrel. Was initially on MTX, plaquenil and minocycline but couldn't get above the lowest dose of MTX because of bone marrow suppression. Went on Enbrel as soon as it came out and experienced relief within days. What little pain I experienced with regular inj was nothing compared to RA pain....have no pain at all with autoject. Some side effects that people experience would occur with RA regardless of being on Enbrel--I know this from being a healthcare professional myself. You just have to weigh the pros and cons and decide if the benefit outweighs the risk. F 48 14 years
50MG 1X W
4/16/2013

 4  anklosing spodylitis(AS) & colitis Burning at injection site for 20-30 seconds durring/after injection. I was diagnosed with ulcerative colitis at 15 yrs old. Sacroilitis kicked in at 20, and I've been on vicodin ever since (9 years). I walk with a severe limp because of the pain half of the time, and experience stiffness for about a hour & a half after waking everyday. My spine has straightened from c8-c1, and causes intense tension headaches that wake me in the middle of the night. My head would hurt so bad that I would use icepacks, pain killers, muscle relaxors and nothing would change the level of the pain. The only thing that helpful was anti-inflammatories, but I can not take those because my ulcerative colitis would immediately flare up and my colon would bleed heavily. My headaches usually last 1-4 weeks, moderate back pain is present 50 percent of the time, severe sacroilitis that leaves me bed bound is once 1-3 days every 3-4 months. I am taking Enbrel injections once a week, and I am looking forward to my 3rd shot in a few days! Since my first injection I have not limped, my back pain is barely noticeable, and my stiffness in the morning is down to 20-30 minutes. My headaches are are a 1 out of 10, and my neck's muscle tension is at a 2 out of 10. This improvement is amazing, and I hope that it will last. I am worried about side effects like weight gain, hair loss, and infections. F 29 2 weeks
50 MG 1X W
4/15/2013
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 4  Psoriatic and Rheumatoid Arthritis After being on this drug for many years I developed a mysterious and severe staph infection in my cervical spine, threatening paralysis. Doctors couldn't figure out what was going on and did emergency surgery and biopsy. Several disc fusions and months on antibiotic fusions, doctors took me off Enbrel, thinking lowered immunity led to staph infection. Was off for two years and tried methotrexate. That was horrible and eventually went back to Enbrel. Seem to get every cold, virus, and sinus infection possible. Resistant to antibiotics. Began this drug many years ago off label before approved. Even with serious complications, being on Enbrel has allowed me to live relatively pain free and function almost normally. Didn't really control the psoriasis though. F 58 15 years
50mg 1X W
3/19/2013
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 3  psoriatic arthritis and psoriasis malignant kidney tumor; loss of teeth due to infection M 52 10 years
50 mg 1X W
2/20/2013

 5  Psa Knot at injection site 4 days after injection. F 32 3 weeks
50mg
2/15/2013

 4  Ankylosing spondlytis no side effects at all. very helpful, but u have to take precautions from changing weather, food habits. i would like to give 4 stars out of 5. good luck !!! M 19 4 weeks
50 mg 1X W
2/3/2013
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 3  RA I was nearly a cripple, prednisone alone not working, then I took one shot of Enbrel and it started working. Now the 2nd week I got a headache, but maybe it's from the pneumoccal vaccine I had to take. Will see what happens at next shot. Enbrel took away the swollen hands, wrists, ankles, knees. I still have pain under my left foot however. Most of the fatigue is gone. F 62 2 weeks
50 mg 1X W
1/8/2013
Email
 5  Rheumatoid Arthritis None now, in the beginning I was fatigued the day after the injection. This medicine really helped me. I went from barely being able to walk (knee inflammation) or use my left arm (shoulder inflammation) for weeks at a time to riding my bike over 3,500 miles this year. I am able to exercise regularly including and live a normal life. After 18 months on the medicine I am thrilled with it. However, I am concerned about potential long-term side effects and continue to monitor other people's experiences with the drug. M 54 1.5 years
50MG 1X W
12/15/2012
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 5  Psoratic Arthritis/Psoriasis No side effects, except tired sometimes It has been great, could not open my hands in morning until hot shower. Nails were all pitted. Feel great now and can grab and hold things with my hands. It has been wonderful. M 52 3 years
50 MG 2X W
12/12/2012
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 5  Psoriatic Arthris Occasional injection site reaction. Fatigue the day after. One episode of cellulitis. This drug has been a miracle, when first diagnosed with P.A. I had just turned thirty and within three months of my first symptoms I had lost all my nails (hands and feet) and was so sore I could barely leave my bed. Without enbrel I truly don't know where I would be. M 35 5 years
1X W
12/4/2012

 2  mild Psoriasis my mild psoriasis has worsen and become plaque psoriasis with red patches and itching. I only have psp in my legs Nedd help...should I stop its usage? will these symptoms go away? F 52 5 weeks
50 mg 2X W
11/16/2012
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 4  psoriatic arthritis feel pretty good, still concerned about some side effects. Especially heart problems, haven't had any yet.I do have tingling in feet on waking in morning. Lots of sinus congestion problems, but I do also have allergies which goes along with this problem. Also was recently tested for vit. D and was low 26, but I had been taking 3000 ius a day. Don't know whyit's so low Iv'e been prescrobbed 50,000 ius for 8 weeks. Drs say it's not from the enbrel. Also been having wrist pain. Do get flu symptoms alot and headaches. If anyone knows of the vit. D problem F 62 8 years
25mg 2X W
11/2/2012

 5  Behcets Syndrome Have experienced some headaches which I wasn't getting before but other than that, nothing. I had a lot of symptoms with BS. Extremely swollen knee, elbow and wrist. Painful pustules on thighs and chest and very spotty generally. Uveitis (eye disorder) every few months. Severe lethargy when having an episode. After taking Enbrel, I noticed a significant improvement within 3 days. 1 year on I'm in perfect health and able to resume a normal life. M 42 1 years
50 MG 1X W
8/28/2012

 5  Pusular Psoriasis I have suffered from Pusular Psoriasis from I was 5 years old & the injection has really helped me, no side effects apart from brusing & redness sometimes at injection site. I am also on the methotrexate for 7 years & that would make me sick but now I have clear skin!! F 15 4 years
50MG
8/24/2012
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 4  Psoriatic Arthritis Bruising and puffiness at injection site, headaches, moodiness, fatigue. On the positive side I can actually move around and be active for the first time in years. I can go out dancing again, camping and keep up with my five year old. Enbrel has definitely changed my life for the better. F 30 2 months
50
8/22/2012
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 5  Psoriasis Slight bruising around injection sight.It has been an awesome med for me I had been fighting psoriasis since I was 7 years old. 2 injections a week well worth it. M 44 3 years
2 x 30mg
8/14/2012

 3  RA Except for an occasional red area at the injection site I had no side effects until a yr ago. They found I had a reduced ejection fraction, 35%, (cardiac myopathy). There is a possibility that this was caused by the Enbrel. I have now stopped this medication. I also take methotrexate which is my drug of choice, it works wonderful. Enbrel afforded some help but I can't do without methotrexate. F 65 6 years
30mg 1X W
6/6/2012

 5  RA No side effects. I take one dose of enbrel once a week, every six weeks. I try to take as little as possible. Usually, I begin to feel my RA during the end of my fifth week. Also, I stopped eating foods that contain arachidonic acid, which is a precursor to inflammation. This acid usually found in red meats and egg yolk. When not taking Enbrel, most of my joints are inflamed beyond belief. I absolutely love Enbrel! F 41 3 years
25mg
6/3/2012
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 5  Psoriatic Arthritis stomach Abscess, infected injection points, weight gain, extremely high LFT Enbrel saved my life psororitic arthritis wise. I yo-yo on and off meds. due to health issues from drug- Liver function results high, so hosp take me off meds. With Enbrel I work a normal day but within two weeks of coming off I am in a wheelchair and unable to work. Frightened loosing my job will mean loss of my independance. I want to work so if staying on Embrel means I can, I fight to stay on it. On the other hand, staying on it is not good for my body, I'm scarred of long term effects. Feel I walk a very thin line. Don't lead the exciting life of a 24 year old because of my illness even with the drug. Go through my day waiting to get home from work and go to bed. Would I recommend it, yes I had immediate results, but as an old school rhemy consultant told me, its not a cure, it just masks the symptoms, so you still have to be careful what you do or you could cause damage to your joints. I however would any day take a few years of good pain free mobility rather than the alternative. Drug wise I am at the end of the line as all the other alternatives do not work for me. M 24 3 years
50mg 1X W
6/1/2012

 5  JRA None Worked amazingly fast. Grandson went from nearly crippled to running full out in a matter of days. He has JRA in both knees, one wrist, started when he was 3. Had already been through cortisone shots and steroids, steroids had nasty side effects (primarily no growth and dental issues). Enbrel is great compared to that. He got used to the shot in no time. M 6 6 months
1X W
5/9/2012
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 4  RA BRUISING AROUND INJECTION AREA ENBREL HAS HELPED ME A LOT I WENT FROM A WHEELCHAIR TO BEING ABLE TO WALK ON MY OWN WITHOUT ANY HELP OF ANYONE OR EVEN A CANE. I DO RECOMMEND THIS MEDICATION TO EVERYONE THAT GOES THROUGH THE PAIN OF ARTHRITIS. ONE THING I DO HATE IS THE STING IT GIVES BUT THEN AGAIN WHAT IS 15 SECOND VS BEING IN PAIN 24/7 F 24 3 months
50 MG 1X W
5/7/2012
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 5  psoriatic arthritis unbalanced , very intense pain in back, very intense neck pain, always tired, deppression, hard to get around ENBREL WORKS 100% , but dont have enough to pay for it. M 52
50 1X W
4/15/2012
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 5  RA Slight bruising if I hit a vein, lasts 4-5 days. Very slight lightening of skin at injection site, lasted 4-5 days. I had RA symptoms as early as October 2011, I was diagnosed Feb 2012. My symptoms aren't severe but I have noticed since the Enbrel I have more energy and my wrist is more functional but that could be because of the prednisone. Sometimes the shot hurt, sometimes it doesn't as much. I'm good with pain but it is impossible not to scream "OWWWWW" for the duration of the shot but it gets easier to take as you already know what you're in for! I recommend this drug! F 27 4 weeks
50mg 1X W
4/4/2012

 3  JRA Bleeding, bruising, swollen lymph nodes, very weakened immune system, redness, swelling and fatigue F 17 4 years
50 MG
3/31/2012
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 4  AS So far I have no side effects I felt improvement from first week I had taken enbrel , now I feel almost 80% of my pain is gone M 66 7 months
50 mg 1X W
3/20/2012
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 4  PA, possible fibromialgia sore, red raised injection sites. injected cold, warm, room temp. no diff. some times severe colds, upper chest,pneumnia conjuction with other med shots, flu or h1n1 shots. worse when others around me are sick pick up different stains of bugs, not severe. i have been off enbrel one time for over a year due to it stopped working. first injection i felt great after 3 days, for 3 years. stopped it, felt like i was run over, went back on and a few weeks later felt ok. agian joints upper and lower and muscles flare up and i am just exhuasted some days.still am after 5 years, benidrel was stated to me of 20ml before injection to help with inflammation of injections.. M 49 5 years
50ml 1X W
2/19/2012
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 4  Ankylosing Spondylitis Big Red Bump, Bruising, The meds. Burn when being injected I was diagnosed with AS and Chondrolysis about a year ago I was so stiff in my hip I could barely Walk. I missed a lot of school and I was miserable. Now enbrel has worked wonders. I am actually running a 5k in June! F 14 1 years
50 MG 1X W
2/8/2012
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 5  Psoriasis and Psoriatic arthritis Virtually no side effects since starting Enbrel PA has improved dramatically. I cannot imagine going back to the way I felt prior to Enbrel. I was taking Arava and had some success but my Rheumatologist thought I could do better with Enbrel and he was certainly right. However, it has not helped my psorasis at all. I have experienced none of the side effects others have mentioned. This has been a life changing drug F 63 7 years
25 mg 2X W
2/1/2012
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 4  Severe Psoriasis Occasional burning during injection, fatigue the day after (although this went away after I took it for a while). I was about 75% covered with Psoriasis and Enbrel cleared it to about 5%. Effectiveness started to wane after about a year, but still kept psoriasis at bay. Try only to inject it into your thighs. I tried injecting it into my lower abdomen as demonstrated on the diagram and I found it wasn't as effective. Also, make sure you get the bloodwork done to check your liver because Enbrel can damage it. Mine is fine thus far, but I'm keeping an eye on it. Otherwise, great drug! After my skin was cleared I felt like a new person and my confidence went way up. :) F 23 1 years
50mg 2X W
1/29/2012

 5  rheumatoid arthritis none this is a wonderful drug after 1 injection I was able to close my hands almost fully without pain, my feet were not as swollen, I could also almost bend my toes and my ankles didn't feel as though there was bone on bone rubbing together, this is an amazing drug and highly reommend it drug and recommend it to anyone who thinks that there is no hope F 54 2 times
50 mg 1X W
1/17/2012

 4  reactive Arthritis I have an injection site reaction, very large area of redness, firmness, warmth and itching. tried heat and ice without much relief, Also more frequent headaches and nausea all my pain went away 2 days after the first shot!!! F 34 3 weeks
50 mg 1X W
12/22/2011
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 4  ankylosing spondylitis Occasional numbness in leg (whichever one I inject it into). Had injection site reaction until switched from auto-injector to pre-filled syringes. I'm still young 20s, and this drug has helped me regain much mobility and energy. Though, I am worried about the long term health issues with this being a newer medication. M 22 1.5 years
50 MG 1X W
12/14/2011
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 5  Ankylosing Spondylitis M 35
50mg 1X D
12/12/2011
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History
 5  Psoratic Arthritis and psorisis From time to time a get a fever the day after my dosage for 1 day. I have been taking enbrel for 6 years and I am not showing any signs of PA. My psorisis cleared up almost immediately, however after 6 years some has come back, however, not the levels I had before. M 45 6 years
50mg 1X W
12/10/2011
Email
 5  Psoratic Arthritis Auto-Injector=injection side reaction BUT did not have with pre-filled syringe. Found injection less burning feeling if not quite room temp. Leave out for only 4-5 minutes then inject. Has really really helped me. However, dr said most his patients only have 50mg one time week. But on the 4th day, I start feeling pain again, in hands and feet and fatigue. So he increased it to 50 mg twice a week. F 28 1 years
50 mg 2X W
12/7/2011
Email
 5  RA Occasional injection site redness and pain. Intermittent hives. Maybe coincidental but 7 surgeries in the last 12 months for basal cell and squamous cell skin cancer. Intermittent dry skin. I will take all of the side effects rather than change from Enbrel. It has been a life changing drug allowing me to live a full and active life. RA had started to attack my lungs and this drug stopped it dead in its tracks. M 65 18 months
50mg 1X W
11/29/2011

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