MESTINON Reviews (PYRIDOSTIGMINE BROMIDE)

Average Rating: 4.0 (82 Ratings)

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 MYASTHENIA GRAVIS

 Type: Rx Drug

  

MESTINON  (PYRIDOSTIGMINE BROMIDE):  Pyridostigmine is used to improve muscle strength in patients with a certain muscle disease (myasthenia gravis). It works by preventing the breakdown of a certain natural substance (acetylcholine) in your body. Acetylcholine is needed for normal muscle function.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5


More on MESTINON: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MESTINONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Autonomic Mild twitching if use cooling vest or forget I took it some hours before. Great medication. Unbelievable that one medication alleviates so many symptoms. F 45 1 years
2X day
7/3/2011
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 3  Myasthenia Gravis I came out of remission after 25 years just before christmas,i have been placed on mestinon since then i have had severe cramps, twitches in muscels,nausea ,loose loose bowels, fatigue F 41 10 weeks
60mg 3X day
4/3/2011
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 3  Ocular Myasthenia Gravis Nausea and Diarrhea. F 57 3 months
60 3X day
2/15/2011
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 5  myasthia gravis stomach cramps fatigue water eyes diarrhea gas it has help me a lot because i couldn't walk, talk,see,or breath i was in icu for 1 month. i was treat by 3 hospital. i was on life support.they had to bring me back 3 times i have been through a lot since november 15 2009. i was a single mother with 5 children now i am married. jerome has been by my side since day 1 and i love him with all my heart .i am still having a hard time but i am dealing with it,thank for the mestion F 38 1 years
90mg 6X day
1/21/2011
 2  Neurologist guessing I have MG.. Urinary incontinence.. a complete emptying of the bladder unexpectedly. Increased sweating of armpits, watery left eye. Has anyone else experienced incontinence? I really can't take it long enough to figure out if it works or not due to the urinary incontinence. I am a medical mystery to many Neurologists, no sure thing to diagnose MG. I am sero neg, but the EMG was indicative of MG (not 100%). F 44 7 days
60 2X day
1/20/2011
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 5  Myasthenia Gravis Stomach discomfort. It gives me the worst gas known to man! It is just annoying more than anything. I was diagnosed with sero-negative MG. I primarily have trouble breathing, swallowing, and chewing, but occasionally, my arm or leg muscles will get weak, too. When I first started this medicine, I was astonished at how quickly I noticed a difference! It has truly made a difference in my life. I almost feel normal, and only occasionally have a bout of weakness. F 28 1 months
60mg 4X day
12/4/2010
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 2  Myasthenia Gravis Diarrhea I don't know what has happened. The first month I was taking it things got better. The muscle fatigue was so much better. Then I got sick a month ago and it's like the Mestinon isn't doing anything to help with the fatigue. I am worse now than I was before taking the Mestinon. F 37 2 months
120mg 3X day
10/18/2010
 3  myasthenia gravis when taken without food or when im hungry i experience severe twitching in arms, legs and stomach, eye lid. because ive taken it for such a long time, it's starting to lose its effects, so i take extra (take it as i need it) and if taken before the shower it does affect the heart beat. F 20 14 years
60MG 6X day
8/16/2010
 5  MG Excessive salivation and diarrhea when starting drug, muscle spasms in feet and occasionaly experience muscle twitching Started 5 years ago when in ICU with MG crisis, intially 4 x60mg now it's 3x60mg along with immunosuppressive drug daily. Virutally symptom free of MG for 5yrs no longer need steroids, had thymectomy and am now about 90% back to normal functioning. Muscle twitching only lasts about an hour or so after taking Mestinon and is annoying but happens infrequently. F 57 5 years
60mg 3X day
8/3/2010
 5   cramps in calves and feet. unexpected bowel movements. these side effects are well worth dealing with since i have the strengh back and am able to go for walks again. mestinon has really helped the muscle weakness that was making my life miserable. I still have trouble with double vision even following surgery to help increase the strengh of the eye muscles. however the doctor wants to redo the right eye. maybe my double vision has hope. F 60 3 months
60 mg 4X day
6/17/2010
 5  MG occasional muscle cramps in legs and feet; loose bowels occasionally; have to pee 20-30 minutes after taking meds; muscle twitching if take too much (doses too close together) still nothing better for my MG....have had MG since I was 12 and been on Mestinon since then. Also take Prednisone (30 years); Mestinon still makes all the difference in my vision and day to day life. Have never been so healthy and strong. Also had thymus taken out 6 months after diagnosis F 45 33 years
45mg 4X day
6/1/2010
 4  MG Diarrhea, stomach cramps, nausea. Muscle twitches if too much is taken. Even with side effects, this drug is amazing. I was completely unable to function at almost any level before finally being diagnosed and started Mestinon. It has brought me back to about 75% of what I was before MG. F 43 5 years
60 mg 6X day
5/9/2010
 4  Myasthenia Gravis Terrible diarrhea until I started taking Loperamide Anti-Diarrheal evey day. Still get severe cramping in hands and fingers. Doc has prescribed potassium for cramping. Also get twitching eyelids when taking Mestinon. Vision has gone from 20/20 to 20/40. had Seem to have to urinate every 5 or 6 seconds. Was also taking 60 mg Prednisone, now down to 20 mg. Still bruise or cut for no good reason. Still weak after 3 months. Tried to play golf yesterday and I hit the ball about as far as my 150 year old grandmother. Still get dizzy without warning. Followed up with bleeding ulcer that my doctor said was caused by Prednisone, then pneumonia, so 3 separate trips to hospital. Hope it's all over now. M 71 90 days
360 mg 1X day
5/6/2010
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 5  Myasthenia Gravis Double Vision, weak arm & legs, laboured breathing, dizziness, very tired even after a night sleep.Cannot walk far, round a SMALL supermarket exhausting. Having been in remission for about 15 years. MG is now back, I was very lucky and was diagnosed early in 1962 because my optician's cousin, was head of Neurology in Manchester UK. Mestinon was prescibed. I am now back on it & having all the usual cramps, so I am taking a anti-spasam tablet which helps enormously. After reading some of notes, I am SO lucky to live in the UK and have an almost free good National Health Service. F 62 40 years
480mg 8X day
3/14/2010
 4  MG Gas, loose bowels, best if taken with food but I handled it ok when I just took it straight. I take a 180 time span at night and feel great in the morning and then I take a 60 mg 2 times a day. Keeps me going. It is a very effective drug for MG. I have had Mg for a little over a year and it made a lot of difference. I had my thymus removed and I am getting along pretty well. I am about 75% of what I was before. The mestinon is making life good again. M 59 1.2 years
180 1X day
3/9/2010
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 4  Myasthenia Gravis Unpredictable and strong bowel movements. Loose Stool. Some Diahrria. Contracted full blown MG in March 2009. Breathing, swallowing, eyes and tongue paralyzed. Spent 9 weeks in the hospital and 4 weeks in rehab. Currently taking one 180 MG Timespan pill per day. Tried increasing it to two per day to improve swallowing difficulty, but bowel problems were too bad. Had 5 IVIG infusions which helped a lot. Plasma Phoresis really helps, but is risky. M 79 8 months
180 MG 1X day
2/13/2010
 4  having myasthenia gravis my side-effects were difficulty in travelling coz of my bowel movement and its bleed. diarrhoea,even more than 10 times a day and it makes me tired. i'm also having stomach cramps/discomfort and the doctors prescribed me with buscopan to reduce the cramps and it helps, a bit. i was diagnosed with MG since april 2009 in Hospital Selayang, Malaysia. actually, the symptoms occured since mid of 2008. i was admitted in ICU(february2009). my symptoms were difficulty in breathing and muscle weakness. when i was secondly warded in april 2009,they diagnosed me as MG as my eyelids drooping, double-vision and weak-jaw,difficulty in speaking. since then,they introduced me with mestinon. i started with 60mg 4 t/day.and now,only 60mg 3t/day. i'm now continue my f/up at GHKL. this drug amazingly increased my strength. thankyou to all selayang and GHKL doctors and staff,they are the best and thankYOU ALLAH. F 39 9 months
1/21/2010
 5  have mg cramps in hands, calves and muscles in back of shoulder. loose stool I take 90mg four times a day. Using this medication let me regain my life.I take Mestinon along with a anti rejection drug named cellcept (Mycophenolate generic). My symptions of MG were diffuculty breathing,drooping eyelids, chocking,couldn't support my head upright, extreme muscle weakness,sleeping approx. 22 hrs per day. Doctors didn't expect me to make it. Good doctors and good medication and a great creator. M 65 5 years
11/25/2009
 4  Myasthenia Gravis Twitching of both eyes, Neck pain, Diahroea,nausia, stomach cramps. I was diagnosed with Myasthenia in 2006, had a full transfusion of infogram, didn't work, Had a thymectomy to remove the thymus and associated tumor. Had radiation treatment on the cancer discovered during the operation. Symptoms held steady for 12 months after the operation, now getting worse by the day. Must always be in sight of a toilet, which makes it impossible to travel. Currently taking Mestinon, Imuran, Prednisone, but still getting worse. Gets that bad that I'm actually disappointed that I wake up. M 51 3 years
10/26/2009
 4  Myasthenia Gravis diarrhea, stomach discomfort. I started with 30 MG three times a day. The first dose made me feel better than I had in months. The dose soon became inadequate. I now take a Timespan at bedtime. I feel great in the morning. I still take 30 mgs four times during the day. They don't seem to be effective. I just want to feel normal again! I'm better with Mestinon than without. My other best friend is Imodium!! F 59 3 weeks
10/6/2009
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