PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Amyopathic Dermatomyositis Unusual strange emotions, agitation, insomnia, fast heart rate during the middle of the night, blurry vision. My rheumatologist prescribed 400mg per day for me but I cut a 200mg pill in 4 pieces to see how I reacted to the drug before I started the full dose. Boy, was this drug awful. The first day, for an hour, I felt mean - that I wanted to pick a fight with someone which is definitely not me. The next day, I felt euphoric and I had the desire to run out on the street and hug everyone I saw. Thankfully, I was able to control these emotions and not make a fool of myself. If I had taken the full 400mg dose, god knows what would have happened. I switched to Methotrexate 7.5 mg per week with 2 mg. folic acid/day and I have very little in the way of side effects. A few weeks after I stopped Plaquenil, I met two people who had Lupus and had been on Plaquenil. They both stopped the drug because of side effects that included anxiety, extreme irritability, being very emotional. One of these people also had pressure build up behind her eyes which her doctor attributed to Plaquenil. F 66 7 days
50 mg 1X day
8/17/2015
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 1  Lupus Broke out in a horrible rash, from scalp to soles. Rash is still not responding to high doses of steroids nor high antihistamines. F 24 4 days
200mg
8/9/2015
 4  for my lupus an Im still taking plaquenil I don't if it's the plaquenil - I have very bad pain on the side of my stomach.I have a polyps in my ovaries an I could do my surgery because of respiratory problems F 56 7 years
200 mg
8/6/2015
 1  RA Panic attacks, anxiety, rapid heartbeat, difficulty breathing, feeling like I am on speed. Generally not feeling well but have an over excess of energy. Trouble concentrating on tasks. Chest congestion, difficulty sleeping Plaquenil worked wonders on my pain, but the side effects are not worth it. I have become someone I do not like on this medication. Short tempered and not able to socialize well. Too bad the side effects were so awful, I cannot take this medication F 50 6 weeks
200 2X day
7/21/2015
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 3  Sjogren No side effects for first 6 1/2 years, then my eyes started hurting very bad. I have been off the generic Plaquenil now for 2 months. My vision is less blurred, both pupils are now the same size and less pain in eyes. BUT, now my whole body hurts so much. Trying to decide which is worse the eye pain or body pain. For now I have decided I can't do without my vision. Needing a substitute for Plaquenil??? Any suggestions? F 58 7 years
30 2X day
6/23/2015
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 5  ra none dr. said only use the name brand.... said many patients on the generic had severe problems. Use with 2mg. prednisome and am in remission (for many years) F 63 11 years
200 1X day
6/10/2015
 1  Lyme disease Anxiety, panic, agitation, anger, couldn't stop crying. I was taking the generic form of this drug (the one with the letters and numbers "HCOS" on each pill) for 30 days with no problems at all. When I refilled my prescription, the pharmacy gave me the name brand (the one with the word "Plaquenil" on each pill). After taking my first dose of the new prescription before bed, I was so anxious, agitated and panicky I couldn't sleep a wink. I couldn't stop crying. I felt like I was on speed, manic, and depressed all at once. It was awful. I took the new pills to the pharmacist and she replaced them with the old ones right away. F 45 1 days
100 mg 2X day
6/1/2015
 3  sjogren's syndrome No side effects Plaquenil helped with body pain and a little bit with fatigue, but I stopped take it, because I don't have medical insurance and it is way too expesive for me now. F 48 1 days
200 mg 2X day
5/20/2015
 1  early signs of lupus Started with rash on neck and chest. It became much worse. Got it on arms, legs, face, feet, hands. Was put on steroids 4 days after onset. Been on them 4 days is not getting any better. Miserable is all I can say othervthan itching terrible. F 46 2 weeks
160 mg
5/12/2015
 1  rheumatoid arthritis permanent ear ringing M 64 1 years
4/28/2015
 5  Sjogrens I get very dizzy off and on. I was diagnosed with Sjogrens in 2014. I DID NOT want to take ANY medication. I had been feeling so exhausted all the time. I could not sleep well. My body hurt all over, my back abdomin, shoulders and my feet ached so bad. I just saw a new Rhuemy 1 week ago who was very compassionate. He asked me to at least give the plaquenil a try. He said it may very well help with my pain and fatigue. Thank You Jesus, my pain is lessened. I am sleeping like Sleeping Beauty. My fatigue is slowly getting better. I went for a short walk monday and tuesday. Yesterday I washed the car. Today I walked around the antique shop for an hour. I feel good. Getting back to my self again, and I have only been on it for 1 week. I do believe in Jesus Christ, the power of prayer and healing. I believe the sjogrens is a SIN issue. A spritual condition of my heart, Where I have harbored self hatred and unforgiveness for things I have done in the past. I am dealing with those issues head on. Forgiving myself and praying as I study the Word of God. I believe God for total healing in my Body. Afterall, He made me in His Image and I am the APPLE OF HIS EYE. I believe God for a Miracle and you can too. Be encouraged. Have Faith from Fifty something :) F 59 7 days
200mg
3/20/2015
 5  Lupus (SLE), Sjogrens (SS), FIbro I have experienced skin discoloration on neck and spots on face. I'm curious to know if it is the cause of my major issue w/Longterm/short-term and immediate memory and fumbling my words?? I did grow up with horrible ADD then got on wonderful Vitamins at 27 - couldn't pay for them Bc stopped wkn in 09 due to all this. But starting them back up thanks to some wonderful Friends Family in Christ! I would like to share Lupus SLE affects ALL Organs-That is the "Difference" between "SLE". So if your heart or Kidney start really giving you problems all of a sudden after 15 yrs being on Plaquenil -I personally if it were me would Stay on it!! I have personally been through the ringer since 2007 with DRS Bc "i don't 'Look' like I feel bad"(so in other words I'm a druggy and a faker and a liar) ~ O how many of U have heard that? Drives me Crazy!!!! After 3 Tries w/SSA/DI I think it Finally may really come thru. Since I started in 2009 Every 6 months I've gone down so bad.:(( Really when I was growing up I lived on Advil then I started meditating myself bc I was hurting so bad... I've gotten so bad I'm now living in my bed reading with meds next to me. Amazing....May you All be Blessed Exceeding Abundantly through your Journey and remember this word in 2 Cor 12:9-10 ~"And he said unto me, My grace is sufficient for thee: for my strength is made perfect in weakness. Most gladly therefore will I rather glory in my infirmities, that the power of Christ may rest upon me. 10 Therefore I take pleasure in infirmities, in reproaches, in necessities, in persecutions, in distresses for Christ's sake: for when I am weak, then am I strong." Amen ❤😊☀ F 48 8 years
200 MG 2/D
2/16/2015
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 1  Lupus Retina detachment in the right eye. Issues with the left eye with floaters and blurry vision 2 years after stopping med. I took the generic hydrocloroquine. Is anyone else having this issue or perhaps in a lawsuit? F 56 2 years
400mg
2/13/2015
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 2  Rheumatoid arthritis Plaqunil helped me a lot but the side effects are horrible. I have had depression with nervousness and suicidal thoughts. My skin exfoliates in sheets. My muscles are weakened and I have problems urinating. I am withdrawing from this drug and I had panic attacks and my heart is racing. My hair is okay but this medicine side effects are bad. I will ebe have to learn to deal with the pain F 59 2 years
400
2/7/2015
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 3  Discoid Lupus Nausea, dizziness, gas, fatigue, diarrhea, some hallucinations, which have subsided as of now, hyper pigmentation, purpura and petechiai med size and small size red pepper dots on skin, have had a rash on abdomen for 3 months now. Not sure if it has caused cutaneous vasculitis, also lots of brown circles on skin, lots of itching. Scalp is still active with discoid lupus have lost hair and thinning as we speak, and I have not had to shave in 3 months. F 48
200 MG 1X day
1/22/2015
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Patient History
 2  Lupus I have been diagnosed with UDCT/lupus I tried taking the plaquenil three times spaced out throughout a year.each time for a couple of days . The side effects are unbarable . Extreme Nervousness, Anxiety , brain fog worse ,and rapid heart beat like I've never experienced. I wish it worked becuAse my energy levels go back up . Did you have any of these side effects at first ? Do they eventually go away . I was wondering so maybe it would be worth sticking it out . I also herd plaquenil is the safest drugs out there for these types of conditions . I am scared to take prednisode or any other "stronger " meds. F 29 3 days
100 1X day
1/17/2015
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 2  sjogrens, osteoarthritis, fibromyal Extreme external vaginal itching. It seems to be lessening the longer I am off it altogether. Quit a couple weeks ago. Feeling much better after going off this medication. Jury is still out as to how I will feel after being off it for a while. Dr. Said I could just quit once I finished my last prescription, since I was showing no symptoms at the time. F 66 1 years
200 MG X d
1/5/2015
 5  UCTD None, only benefits I had side effects for about 2 week when first taking Plaquenil. I got headaches, sneezing, runny nose etc for about 1/2 hour each time I took it but persevered and so glad I did. 8 years on I am on a maintenance dose of 200mg with no side effects whatsoever. Also have gone wheat, dairy and sugar free, this has all but ceased my symptoms. Have tried cutting back the plaquenil as I was feeling so good but still need maintenance dose daily. F 55 8 years
200 1X day
11/29/2014
 4  SLE? Stomach upset, dizzy at times. Its hard sometimes to distinguish what may be a result of the meds and what is caused by other factors......diet, exercise, age, etc. Had skin issue 10 yrs ago. Blood markers(low white cells and elevated ANA) were consistent with SLE. Have been reluctantly taking Plaquenil now for 10 yrs. Even though my blood results are now good Doc says "better to take it and keep the SLE in check than to try to control it with steroids if it flares...."Plaquenil is safer than aspirin". I REALLY DISLIKE this style of doctoring of you must take meds out of FEAR. M 58 5 years
200 1X day
10/13/2014
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 1  Supposedly Lupus I became very tired and weak. Had to be admitted to hospital because my platelets dropped to 1000 and blood count was 3. I had to get 6 pints of blood and 4 pints of platelets. After a couple of days my numbers dropped again. Was diagnoses with Medicatiion Induced Aplastic Anemia. Have not taken Plaquenil in about 5 months with the help of blood and platelet transfusions and ATG treatment to rebuild my immune system and bone marrow. My numbers are creeping back up. My doctor would see me every 3 months in which he stated that I had anemia. After reviewing medical records he wasnt sure if I had Lupus but still was taken medication. BEWARE..... WHATEVER WORKS FOR ONE MIGHT NOT WORK FOR ALL. F 37 1 years
200 2X day
9/30/2014
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