Average Rating: 2.7 (46 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 4  UTI occasionally Some vision annoyance but temporary. Surprised it can increase libido when neither husband or wife expected that F 71 30 days
2 mg per w 2X W
 5  Urinary tract infections and atrophy No side effects. Energized and feel young. No vaginal dryness and sex drive on point. F 68 5 months
1 gram 1X W
 5  Vaginal dryness/post ooophemectomy no dryness, no vagina pain, I went through surgical menopause so I never really went through hot flashes. I do see how women take a much smaller dose so I am going to try that. 14 years on vaginal cream - 10 on Premarin and it caused a lot of weight gain. I had a break but had extreme vaginal pain and dryness, then I went back on Estrace. I did not gain weight when I was using this drug. However I now exercise daily and stay away from flour, pizza and all fried food. Oil in the diet is essential (avocado, Olive oil, canola oil) if you want healthy cells. F 61 14 years
4mg 1X W
 2  Vaginal atrophy Major, MAJOR bloating (I look pregnant). Stomach pain, stomach achiness and tightness. Pain reminded me of when I was on fertility drugs and was in the ovulation phase. F 49 14 days
1 mg 2x we
 4  Menopause No side effects with this medicine. A good alternate to Premarin. F 50 2 years
 1  atrophy itchy scalp, hair loss, dark facial spots, anxiety attacks stopping this medication, would not recommend F 56 3 weeks
1X W
 1  vaginal dryness Flu like symptoms - headaches (which I rarely ever had in the past) and a migraine so severe that I had to go to the ER. Fatigue and nausea. I used Premarin vaginal cream for years, with no side effects. I tried Estrace because the co-pay was less than Premarin. F 70 3 months
2 grams 3X W
 2  Hot flashes I am stopping this drug. Stomach ache for days, bloating, irritability, severe low back ache. For the first 24 hrs after a dose I would feel fuzzy headed, dizzy, worse hot flashes than before. Iím going to look for a different / natural alternative. F 52 14 days
1 mg 2xWk
 4  Vaginal atrophy Bloating. No weight gain but uncomfortably bloated abdomen with some intestinal discomfort. I started doing every 3 days then every 2 and that helped on the off days anyway. Worked within 2 weeks! Intercourse was virtually painless and I was so ecstatic! F 54 1 months
1mg 1X D
 1  Dryness , painfull sex Gained 10 pounds in one month , I also had sever shoulder pain in my right shoulder. I got very bad hot flashes and dizzy at times. My stomach was very looked like I was o months pregnat . F 51 4 weeks
 3  Menopausal symptoms, hypothalamic Horrible headache, spaced out, nausea, irritable, out of it My Gyno has me take 8 mg for 3 days and then 4 mg for 26 days. I was stupid enough to follow his orders and now feel like hell! Everything I've read says to start with a lowest possible dose! Why does he pump me up with estradiol like that? I've got a splitting headache, nause, irritable as hell. Yes, I feel stoned and not anxious but I could also take Xanax to manage my anxiety. I'm going to lower my dose. F 40 2 days
8mg 1X D
 1  atrophy Awful, 1st dose-severely nauseous,no appetite , anxiety 2nd dose -same as 1st plus severe anxiety,racing heart, confusion with high BP so bad had to go to ER. Still having panic attacks 3 days later. I only used 1/3 of dosage dr recommended 1 month apart. Was prescribed 3 times a week. Would not recommend! F 56 1 months
2X M
 1  Hrt Heart palpiations and anxiety (fight/flight feeling). The longer I took it the worse the symptoms got as well as the frequency. In the beginning you don't give a whole lot of thought to a palpitation because they were so infrequent, but the last 7 months things really flared up. One day shortly after taking the Estrace, the palpitations started and I remembered it had actually happened the last 3 days after taking it. I finally had something to tie it to. That was the last time I took Estrace. It's Been 1 Week Today AND I'm still getting them. I also found out that it'll be about 6 weeks before the drug is out of my system so I'm praying I start to few better soon. The heart scares me when it's not beating right! F 52 3 years
 5  Pelvic floor prolapse Solved many problems with no side effects. F 67 60 days
1 2X W
 5  Painful intercourse Intercourse was very painful would avoid my Husband like the plague. After 2 weeks of Estrace cream my sex life is wonderful and my boobs are bigger. I would highly recommend. F 55 1 days
10 mg
 2  Vaginal dryness and thinning Hair loss, sore joints, sore breast and bloating feeling. Cold feet and hands. I would not advise taking this. F 59 3 months
Twice a we
 3  Dryness Nausea. Insomnia. Drug seems ok, nausea is irritating. Too nauseous to eat much. F 45 2 weeks
1 mg
 4  hysterectomy & vag reconstruction no side effects, still have hot flashes, but it helps F 49 10 months
42 2X W
 1  Atrophy Bloated up immediately, bad dreams and severe blood clots. Scary F 49 9 days
 1  vaginal atrophy Chills, insomnia , nausea, bloating , weight gain, diarrhea, body aches This stuff literally made me sick. I thought I was fine until I reached the two week Mark. I seriously felt like I dying. I couldn't keep myself warm and I live in Florida. I will try an organic product. F 59 1 weeks
1 mg

ESTRACE  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   (Sources: U.S. Centers for Medicare Services, FDA)