IMIPRAMINE HYDROCHLORIDE Reviews

Average Rating: 3.5 (105 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on IMIPRAMINE HYDROCHLORIDE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR IMIPRAMINE HYDRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Insomnia, anxiety attacks I tried weaning myself off 8 weeks ago since I felt it had run its course. Within 3 days I developed tinnitus (ringing in ears) and IBS (irritable bowel syndrome). Two weeks later I was lethargic, emotional, irritable and mildly depressed. By week 5 I had actually resolved the insomnia on my own but my stomach started getting worse and worse each day. I thought I had a urinary tract infection. I was bloated, constipated, emotional, lethargic, and mildly depressed. I continued to cut the dosage. Even consulted an herbalist and became a vegetarian. I finally got an emergency appointment with my doctor today, begging for a colonoscopy. Unfortunately, as I suspected, she told me to go back on the imipramine and that once I was back to 100 mg all of these physical symptoms would be reversed. Bottom line: as much as I hate being on something like this and I feel it may be toxic in the long term, I can't live with these side effects, or apparenly, without the imipramine. My doctor explained that I will probaby be on it for the rest of my life. I am ambivalent about this diagnosis, since I feel my anxiety and insomnia issues have been resolved, however, my quality of life over the past 8 weeks of going from 100 mg to 25 mg has been horrendous. Just my two cents... F 52 20 years
100 mg 1X D
6/27/2013
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 4  Too many Nightime trips to bathroom vivid, sometimes crazy dreams sure seems to work M 62 2 days
75 mg 1X D
5/10/2013
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 3  Panic disorder, depression Unusual tiredness, dry mouth, feelings of fainting, floaters, can't get up fast, really muddled thinking, weight gain, crave sweets, had to be put on strong laxative because of constipation F 17 1 years
50mg
10/13/2012
 4  panic attacks/anxiety Dry mouth, trouble urinating, twitching of muscles (especially at night). F 47 2 months
50 mg
7/7/2012
 1  urinary incontinence doctor prescribed 50 mg per day, with no gradual introduction of drug; noticed immediately increased agitation; anxiety; dry mouth; bitter taste in mouth; impulsive behavior; suicidal thoughts; memory loss; ended up in emergency room for suicidal rant, worsened by drinking alcohol F 67 3.5 weeks
25 mg 2X D
3/18/2012
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 4  Depression Dry nose and sinus, drowsiness, sleeping in, difficulty getting out of bed. Helped my depression tremendously. Makes me feel calm and relaxed, and not prone to lose my temper or become frustrated. Stops self-punishing thoughts and repetitive, anxious rumination. The only side-effect which really makes it hard to take is the dry sinus: my nose and sinuses become very sore, dry and itchy, and it drives me mad! May be because I also drink a bit of coffee etc., but I never noticed this problem before I started this drug. In spite of this, it's still the best AD I've ever tried. M 38 4 years
50 mg 1X D
3/17/2012
 2  Pain relief, hip and back Dry mouth, trouble sleeping, restlessness, one episode of diarrhea, headache. It did relieve about 80% of the pain which was great, but not hypersensitive skin. I'm going back to my dr to seek an alternative as I doubt I could work full time with these aside effects and believe the risks associated with this drug are too great. F 32 1 days
10
3/5/2012
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 5  Major Depression and ADD Dry mouth, Strange taste on mouth, more willingness to smoking, episodic memory fog and muscle weakness. Great drug. It helped me with the depression and the excessive sleeping. My concentration is a little better, but I still need to take ritalin together to treat ADD. The muscle weakness, fogged episodic memory and loss of libido helps me to relax. M 21 4 months
75mg 1X D
1/29/2012
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 1  Panic disorder I started Imipramine about 6 weeks ago ans began with 25 mg a day for 7 days then upped it to 50 mg for the rest of the duration per doc's orders. After 4 weeks I was getting excited and not the good kind then 5 weeks I had more panic attacks back to back then I ever had before in my life. Then week 6 I wanted to die, I called my Doc and told them I couldnt leave the house I was so bad I couldnt sleep and I had around a dozen panic attacks per day. Scared me so bad that I really thought I was going to be hospitalized. Luckily I began to taper off 4 days before my emergency visit with the Doc and today Im back in Zoloft, this time I will deal with the sexual side effects b/c being in panic mode 24/7 is not cool and makes you wish you were dead. Now since Ive been weeing off of Imipramine I have had these terrible headaches but eveyone is different and the reason I was prescribed Imipramine is b/c I "failed" about 7 other anti-depressants. But this one is by far the worst I have ever and I mean ever had to deal with. Now with the help of 5mg of Xanax and my zoloft on the rise and EFT techniques and CBT therapy and Faith in God I am just starting to see the light, also I quit drinking and using tobacco 3 years ago all on my own and that was like taking a piss compared to the Imipramine reaction I experienced. But Im not a D-bag and I know everyone reacts differently to each Anti-depressant so that is just my story with this med. Im an OIF Veteran and struggling everyda M 27 6 weeks
50mg
1/7/2012
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 2  Urinary Incontinence,Stomach issues Heavy sweating w/bursts of heat so bad people next to me feel it explode into a heat wave, can't sleep, fast heartbeat, sugar cravings, constant headache Has helped with my restless legs, but not given to me for that. Sweating is insane, can only sleep at a very shallow level if at all. I am exhausted and fatigued all day and not functioning. Had to temporarily stop P/T because I am just so tired. Trying to get hold of doc. F 48 30 days
1X D
1/6/2012
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 1  sleep I gained 20 lbs, had severe dizziness upon rising, dry mouth F 48 3 years
150MG
12/7/2011
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 1  Trouble swallowing food Can no longer ejoculate I took it for swallowing difficulty. I still cannot swallow food or beverages, but now I cannot ejoculate. I am getting off of this drug now, M 49 30 days
25mg 1X D
10/23/2011
 1  Depression Racing heart, suicidal thoughts, rage, nervous feeling, hyperarousal, adrenaline surges This antidepressant made me SO MUCH MORE DEPRESSED. I guess because I have paradoxical reactions to all psych meds. I had psychotic symptoms as well as manic symptoms. It made me suicidal, very rageful too. I also felt hyperaroused (and was misdiagnosed as having PTSD), extremely anxious, could not sleep well while on it, had adrenaline surges which made me angry for no reason. Withdrawal has been very painful too both physically and psychologically, but I am having windows where I feel like myself again and it gives me hope. F 34 3 months
75 mg 1X D
9/26/2011
 5  SEVERE LEG PAIN FROM NERVE IN BACK THIS MEDICINE STOPS THE PAIN CYCLE OF LEG NERVE PAIN & EVENTUALLY EASES SHARP PAIN DURING THE DAY. IT ACTUALLY SAVED MY LIFE BECAUSE THE PAIN WAS SO SEVERE. A DOCTOR IN LAS VEGAS PUT ME ON IMPARMINE I HAVE A LITTLE PAIN BUT NOT SERIOUS LIKE BEFORE I CAN FUNCTION ALL DAY WITH OUT MUCH TROUBLE THE MEDICINE LELAXES THE LEGS & STOPS THE PAIN NIGHTLY I WOULD RECOMEND ANYONE SUFFERING FROM SEVERE NERVE PAIN IN THE LEGS DUE TO A BACK INJURY BE PUT ON THIS MEDICINE IT IS VERY VAULABLE TO STOP THE PAIN CYCLE & FUNCTION THE NEXT DAY F 69 10 years
50 1X D
6/4/2011
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 1  Narcolepsy Nightmares and Night Terrors I started taking this drug to augment other medications I take for Narcolepsy - my daytime wakefulness is well controlled but I need a sleep aid. I have never had nightmares; I've had bad dreams but I would never have categorized them as nightmares. In the six weeks I've been taking Imipramine I've woken up almost nightly from the most vivid and tragic dreams drenched in sweat, out of breath, thrashing, and sobbing. This morning I woke at 1am from a horrible dream to find that I was beating myself in the face and head with my fists. The prescribing sleep medicine specialist dismissed my concerns and I will be seeing another doctor today - bruised face and all. Side effects be damned - I will NEVER take another, single Imipramine pill ever again! F 37 6 weeks
100mg 1X D
2/3/2011
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 5  Major Depression/Anxiety dry mouth, low-to-no libido, insane sweet tooth, excessive sweating in summer, Had terrible anxiety/panic attacks and depression for 8 months after my daughter was born. A GP had prescribed Elavil and Xanax, but that put me into a drug induced fog. I stopped the Elavil but continued the Xanax. Another GP told me to stop the Xanax, so I tried to do so but was unable to. I then got brave enough to see a psychiatrist who put me on Imipramine (25mg/day) and weened me off the Xanax. He gradually increased the dosage. It took about 10 weeks, but all of a sudden the black cloud lifted. Since then, i've been at a 250mg maintenance dose. About 13 years ago, my doctor tried switching me to Prozac. I gradually stopped he Imipramine while taking 20mg/day of Prozac. Once the Imipramine was stopped altogether, I felt like I couldn't sleep and had awful dreams that I would think about all day until I had new ones the following night. I spiraled back down very quickly. My doctor stopped the Prozac and put me back on Imipramine and ramped me up to 300mg/day. it took me about 10 months to get back to "normal". Imipramine is a miracle for me and well worth the side effects. M 54 27 years
250mg 1X D
1/20/2011
 5  Depression Taken for 20 years F 70 20 years
25mg 1X D
11/28/2010
 4  mild anxiety, depression Excessive sweating, weight gain My only complaints are weight gain and absurd amount of sweating. I sweat buckets at the least feeling of heat or when I'm under pressure. Tried many times to reduce dose and quit but anxiety always comes back. This drug works really well for my anxiety, I just HATE the sweating. M 47 3 years
25 mg 1X D
10/21/2010
 4  panic attacks and agoraphobia initially dry mouth, hard stools, some tremors in one arm. chew gum or suck on a candy with dry mouth, and stool softener works well when needed. just live with the tremor. my father took imipramine before me for 30+ years, and i have taken it for 33 years. my dad went off it due to his skin getting very dark after years of use. his skin lightened after going off the medication and switching to zoloft. i have used the meds for panic disorder and agoraphobia. i have consulted with psychiatrists over the years to determine if there is a better med. all the docs have said stick with what works, and i am doing so. M 63 33 years
150 1X D
9/19/2010
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 4  Insomnia Hair loss but I had some before I started these meds and 1 week of worse depression but I held on knowing it would get better. I take 100 trazodone, 50 mg Imipramine, .50 xanax and 8 mg Rozerem every night. I wake up usually 2 to 3 times a night but usually get 5 hours straight sleep. Also I read in my oxygen magazine 1000 mg of calcium and 500 of magnesium would help too. It does seem to help. F 37 2 years
50 mg 1X D
7/5/2010
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