Average Rating: 1.8 (333 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on HYDROCHLOROTHIAZIDE: Reviews Summary  |  Drug Safety Information

 2  High BP Heart racing.... scary! Occasionally would have chest pain M 60 28 days
25 1X D
 1  High Blood Pressure Extreme fatigue/tiredness, chest heaviness, headaches, dry mouth, dry eyes, sadness, feeling depressed, crying Started taking this medication 3 weeks ago and began to experience extreme tiredness. I also realized that my mood changed. I was feeling sad, low spirited, no motivation or energy for simple tasks. I had to force myself to do basic tasks. I had episodes of crying randomly out of no where. I stopped this medication for 1 day and hope that I start feeling like myself again very soon. Awful side effects. I will contact my PCP and notify him . F 53 3 weeks
25 MG 1X D
 3  High blood pressure It helped with water retention but caused some unwanted effects. Such as brain fog and short term memory issues, leg cramps, joint aches and racing heart rate. F 36 2 years
6.25mg 1X D
 1  Hypertension Took 12.5 and one hour later had full blown panic attack....Am also taking 40mg Benezipril will stick with this HCTZ is a horrible drug with many side effects not listed as money is the bottom line. Eat well exercise and stay away from this poison .... F 78 1 days
12.5 1X D
 3  High Blood Pressure I take 20 MG mixed with 12.5 MG of Lisinopril and 5mg of Amlodipine. After 5 days I started having panic attacks, I mean crying episodes and I never experienced this in nt life.. It also caueses a racing heart beat, nausea, chills, dizziness. Waking up from sleep having panic attacks. I guess it lowered my BP but the side affects are terrible. M 58 7 days
20 1X D
 5  High Blood Pressure I have been to the ER a total of five times taking this. Each time afraid for my life thinking I was have a heart attack. Was on a family vacation and had to miss out on an activity and go to the hospital. No telling what damage it's done to my system as I've been taking it for a year. I just now thought to check reviews and have come to realize other people were experiencing the same thing. Heart palpitations, dizziness, light-headed, body pain, insomnia etc... don't take this sh*t! M 38 100 days
25 1X D
 4  taking w/another HBP med occasionally light-headed; take with 80mg Valsartan. NEVER had fluid retention issues. seems to work ok in combo w/Valsartan BP fluctuated alot so this was added to the Valsartan. I always drink lots of water, have never retained water, no other health issues other than HBP. Not overweight F 72 1 years
12.5 mg 1X D
 2  Water retention & slightly high BP HEART RACING to the point of panic I started taking this at the same time as another 10 day course of medicine, so it took me a while to realize it was the HCTZ causing racing heart. It would beat so hard and fast at rest that I couldnt sleep! So many people complaining about heart racing. Why isnt this in any of the side effect lists?! F 41 14 days
25mg 1X D
 1  High blood pressure I share all terrible side effects I am reading! Please discontinue this drug! I'm scared! Numbness in hands legs and feet, racing heart rates, pain in hands arms and chest, anxiety, I am feeling pretty terrible! Please do not kill me! I have a 3 year old and two older sons to live for! F 43 1 weeks
25 1X D
 1  High blood pressure Insomnia, racing heart, chest pain, temple pain, numbness in hands and sometimes legs. I literally searched to see if anyone was having the same side effects as I was. Come to find out other people are experiencing the same ones! I've been having insomnia panic attacks going in the my almost third week taking it. I know it takes time to build up in your system but almost right away I was feeling chest pain, tingling limbs and pain in my temples. On my almost third week taking it I started having horrible insomnia panic attacks. I stopped taking it 2 days ago and I'm still having side effects. Just hoping this hell of a drug will be out my system all the way soon. I can't believe they are prescribing this medication to people. They don't tell you these side effects!! F 30 22 days
25mg 1X D
 1  HTN Anxiety, chest tightness, panic, brain fog, dizziness, head pressure, feel like just falling over. Horrible F 30 32 days
12.5 mg 1X D
 1  Blood Pressure Racing heart, sugar, magnesium and potassium levels all over the place. Insomnia. Aching back and kidneys, bladder leaks. Worst Blood Pressure medication. Back ache and kidney ache along with racing heart and insomnia. Stopped taking it after 10 days and my bladder became leaky two days AFTER I stopped taking it. Still happening after two weeks off it. Found out this medication can cause “bladder spasms” aka leaky bladder. This wasn’t listed on side effects handout, I looked at a medical journal and saw it listed! This was NOT happening to me before I took this. This drug should be taken off market! F 48 10 days
12.5 1X D
 1  Hbp Chest tightness, fatigue, muscle pain, headache dry eyes, anxiety and heart palpitations... M 55 4 months
12mg 1X D
 1  Hypertension Completely changed my emotions! I was starting to notice that i was feeling irritated at everything and everyone no matter what. I started feeling very depressed and i was getting random chills off and on along with my chest feeling like it was pounding. I will be no longer taking this junk!! Fixing to try walking or something else. F 43 4 days
25 1X D
 1  BP Feeling feverish but no fever, stomach hurt, mild headaches, taking deep breath's due to anxiety, just feel like shit I need to get off this immediately and it needs to recalled! M 33 4 days
25 1X D
 1  Elevated blood pressure Dizziness, weakness, slight headache, swim like feeling, head pressure, tinder under and above eyes... the list goes on Been put on this medication due to my birth control pills that cause me to have elevated blood pressure never had high blood pressure in my life, went to the doctor and she put me on this horrible medication for 2 months to get it back to normal, it's been 2 weeks and I feel like crap with all this weird swim like feeling and pressure this started two days after taking this medication decided to read the review and look what we have here.... the absolute worst I will be calling my doctor in the morning because this is ridiculous I can't deal and if they do nothing or switch me then I will find another doctor. F 27 2 weeks
12.5 1X D
 1  Hypertension Didn't sleep for six days, depression as I've never imagined. I hardly ate for the entire time I was on this poison, so I lost weight and look great. Probably won't go to the beach, though, because of the debilitating panic attacks. The muscle cramps are merely a side note, and they're horrible on they're own. Why would I be surprised that Satan is involved in the pharmaceutical industry? What a perfect place. Just didn't know he helped to develop drugs. I use that word very generously, too, this is a drug the same way bubonic plague was a bad influenza outbreak. It is truly a poison. At least in my experience. M 56 6 days
12.5 1X D
 1  High Blood Pressure Works great for making you urinate to get excess salt and water from your body but I have Migraines for hrs on end. Its horrible, i dont even have headaches so for me its unbearable and I wont be taking anymore. M 34 1 days
25 1X D
 1  High blood pressure This is the worse medication in modern history, literally ruined my life, I am so happy I traced but I found out wha was causing these problems. Headache, anxiety, nausea, chills, heart racing, depression, loss of appetite, and the list continues. F 41 7 days
15.2 1X D
 2  osteoporosis and high blood pressure migraine, bad nausea, very thirsty, joint pain, dry eyes and sick feeling I stopped taking it F 53 5 days
25 1X D

HYDROCHLOROTHIAZIDE  (HYDROCHLOROTHIAZIDE):  This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide belongs to a class of drugs known as diuretics/"water pills." It works by causing you to make more urine. This helps your body get rid of extra salt and water. This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.   (Sources: U.S. Centers for Medicare Services, FDA)