TRAZODONE HCL Reviews (TRAZODONE HYDROCHLORIDE)

Average Rating: 2.8 (229 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

TRAZODONE HCL  (TRAZODONE HYDROCHLORIDE):  This medication is used to treat depression. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.   FDA Approval Date: 1986-10-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on TRAZODONE HCL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRAZODONE HCLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Insomnia Increased libido? I'm horny as hell, but I don't know if it's the pills. 25 mg. Calming of racing thoughts at bedtime corellated with start of treatment M 34 1 years
3/8/2006
 4  Depression This medication certainly isn't without side effects (but it's been said that any medication that does not have side effects, likely will not work)! Here we go: dry mouth, sedation, improved quality of sleep, constipation, increased appetite, feeling out of it all the next day, increased libido, increased frequency and quality of erections and ability to reach orgasm (no complaints about that one), dry eyes and occasional minor visual disturbances. As with most medications, the side effects are most noticeable at first and when the dose is increased. The good news is that if you take it easy and go up relatively slowly, most of these side effects will diminish with the passage of time (although I'm still going up to a max of 600 so I will likely have to deal with them for a while longer every time I increase the dose). I'm writing this primarily for those that might be researching this drug and are just starting or are considering trying it for depression related conditions. I asked my doctor to consider it since through my reasearch I learned that it was related to Nefazodone (which I did very well on for years before it was pulled from the Canadian market). This drug is classified as an SARI (serotonin antagonist reuptake inhibitor), which is to say that it is both a serotonin antagonist (a lower doses) and a serotonin reuptake inhibitor at high enough doses. This makes the way it works different from any other available antidepressant (except for Nefazadone, which is essentially an improved version of Trazodone that is still available generically in the States (wish it was available in Canada). It's brand name (Serzone) was discontinued after several less than convicing reports of liver failures requiring transplants ( the risk is something like 1 in 250 000 and I would take it again in a heartbeat). Some of the advantages of Trazodone over much more popular drugs such a Prozac, Zoloft, Effexor ect... are that it actuall has no detrimental effect on the quality of sleep (something which the SSRI's and SNRI's definetly mess with). It has a strong calming feeling so it could be good for certain people who struggle with anxiety and have trouble sleeping (it is not addictive or habit forming). Most importantly for me anyway, it has considerably less sexual side effects as compared to m M 42 5 weeks
400mgs 1X day
1/21/2011
 4  sleep great drug. BUT painful 4 hour erections in the am M 40 6 months
1X day
6/16/2010
 3  insomnia and depression Terrible back pain started after a few weeks of taking trazodone. Also constipation. Back pain resolved within days once i stopped taking it. Works well and helps me get a good nights sleep. M 32 6 weeks
50mg 1X day
5/16/2011
 3  Insomnia None My doctor prescribed this for insomnia and while I guess it helped somewhat, it wasn't something I'd rave about, either. I thought it was the dosage, as 50 MG seems like a small amount and my sister used to take 300 MG for her insomnia. The good news is that I had no side effects. Eventually, due to its lack of effectiveness on me, I asked my doctor to switch me to something with a bit more "kick" and he put me on another medication. Maybe it would have worked better at a higher dosage. M 27 5 months
50 MG 1X day
9/13/2012
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 3  Insomnia Dizziness,fainting,hangover feeling nextday, and heavy feeling I passed out twice and hurt my damn self on this stuff. M 16 3 weeks
50-300 7X W
2/28/2012
Email
 3  Anxiety And deppression Tiredness My psychiatrist wanted to double my tablets, but I said I did not want to do this as I felt that they would make me very tired when I go away on holiday,even though I have anxiety and deppression. I have spoken to him since about this. M 44 1 years
7/29/2004
 3  SLEEP MAKES ME VERY SLEEPY AND KINDA HUNGOVER THE NEXT MORNING WORKS VERY WELL FOR SLEEP. REALLY KNOCKS ME OUT..BUT I HATE THE FEELING THE NEXT MORNING. I TAKE 150MG ON/OFF AS NEEDED. SHOULD TAKE ON REGULAR BASIS SO I CAN GET USED TO IT... M 33 1 years
5/9/2008
 3  Hard time sleeping Very groggy in the morning I was prescribed this because of my trouble falling and staying asleep. Very cheap and works ok but would make me very groggy in the morning. Make sure you take this at the right time. M 27 2 months
6/8/2009
 3  Insomnia None I was prescribed Trazodone after dealing with a bout of insomnia that required some medical attention. The first few months of taking it, it did help me fall asleep faster, but I am not convinced it was just the medication. I think some of it could have been psychological. It never made me feel overly sedated and I could stay up for hours after taking it if I wanted to. A month ago, I decided I would try to stop using it since I debated whether it actually did much of anything, and I quit cold turkey. Do not ever do this. The second night without it, I had what I can only describe as severe panic attacks and sweating, nausea, shakes, etc. I quickly realized it was withdrawal. All the literature I'd read on it said it should not be this severe. Well, it was. I also did not sleep for four days and would sweat profusely throughout the day. I finally gave in on the fifth day and took it at night and slept for 12 hours. I know to wean off it slowly next time (but for now I am just going to keep taking it). M 28 1 years
50 1X day
3/16/2013
Email
 3  Insomnia Severe headache... Dry mouth... Off balance... Hope it goes away... M 29 4 days
50Mg
5/23/2016
 3  Insomnia and anxiety Fatigue and sore muscles (especially in legs); can't walk more than a mile before I start limping. Also have mild itching/needle feelings all over. As others said, I also get a stuffy nose while sleeping. Man, this stuff really, really helped me finally get some sleep. I'm just hoping that the side effects kind of go away. I'd like to keep taking this for the sleep help, but if I can't exercise and am itchy all the time, that's kind of a deal breaker for an active lifestyle. M 33 5 days
50 MG 1X day
2/9/2022
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 2  Insomnia Helped with insomnia but I could not deal with the other side effects. Horrible muscle pain in legs and arms. Also felt like my skin was itching and crawling especially in my lower legs. M 41 2 months
50 mg 1X day
4/14/2022
 2  Sleep Sleepiness, dizziness, anxiety, lack of motivation I was on this drug for 15 years for sleep. In the beginning it was great for that. My body became dependent on it and it definitely caused big spikes in anxiety. I finally tapered and got off it three months ago, but am still feeling symptoms of withdrawal. My vote is stay away from this drug! Has anyone felt withdrawal symptoms this long? M 44 15 years
50-100mg 1X day
8/17/2020
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 2  depression myalgia, headache, weakness, sinus blockage, stopped breathing whilst asleep, heart burn. did nothing! for depression. but was! very good as a sedative. i stopped taking it because it made my legs ache. taken in high doses it acts like an ssri (but the side effects would be horrendous) at lower doses- it's a potent sedative. odd. M 48 1 years
150mg 1X day
9/25/2017
 2  Insomnia (trouble maintaining sleep) Awful legs/arms pain. Weakness. Headache. Diziness. Blurred vision. Muscle spasms. Took this as a replacement to mirtazapin. I started taking 25mg at bedtime. After 4 days my legs were so painful that I couldn't walk more than 5 minutes. I felt so weak, I thought my hands were going to fall off my arms! I halved the dose to 12.5mg for a few days, this eased the pain in my limbs. But I was still feeling dizzy the next morning, with confusion and excitation during the day. I don't even think that it's making me sleep, I just feel high, not rested. Won't be taking it anymore. M 45 7 days
25 MG 1X day
7/10/2018
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 2  Insomnia primarily Lethargy, groggyness, anxiety, confusion, memory loss, blurred vision, paranoid. It worked well for the insomnia, I was able to fall asleep in appropriate amount of time, only waking once during the night and able to fall back asleep. I feel it calmed me down once I was in bed, and I was able to sleep. The side effects were just too bizarre however, I didn't feel like myself. I felt out of it and really down the whole next day. I took it for 5 days and quit. I kept feeling okay, then not okay, then okay. M 25 5 days
50mg
12/21/2016
 2  insomia, anxiety, manic depression Heightened insomnia, slight headache Well... I took one 50mg tablet at around 6pm hoping to fall asleep shortly. Never happened. Around 10pm I took another 50mg tablet. I was absolutely restless in bed tossing and turning. Temperature was screwed up, kept feeling hotter than usual. Was able to fall asleep for a few hours maybe 3 or 4 until I woke up at 4am. After not being able to fall asleep again I decided I needed to upload my experience. Although this is the first night ive tried it, I hope it works tomorrow. M 19 1 days
50mg
5/15/2015
 2  insomnia/depression/anxiety Ears feel like they are slightly blocked. I work over nights and I last went to bed on Tuesday morning (May 19/2015) and I have not slept while taking this medication I was prescribed this medication for insomnia/depression/anxiety and have not slept in 2 days. First night I took,I slept 3 hours and felt groggy,dis-orientated,shaky and out of it(not feeling right).I took my pill at 1:30pm today and it's now 4:15pm.I am not taking this anymore M 48 2 days
50mg 1X day
5/21/2015
Email
 2  Insomnia from steriod enjections Blocked nose, shortness of breathe and severe reflux with nausea. Do not use if you have RLS. This medicine will (may) exasperate your RLS beyond belief. Everyone reacts differently to medicine, but this pill drove up the wall all night. M 43 1 days
50 MG 1X day
2/12/2015

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