ESTRADIOL Reviews (ESTRADIOL)

Average Rating: 2.7 (60 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

ESTRADIOL  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   FDA Approval Date: 1996-03-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ESTRADIOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ESTRADIOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  HRT after hysterectomy MIGRAINES, hot to cold flashes,night sweats,rage,depression,emotional rollercoaster,pain in joints and back,sharp shooting pelvic pain,foggy head,memory problems,constant food cravings I had been on PREMARIN 1.25 until my insurance company decided to switch to ESTRADIOL thus forcing me to change. I had been on ESTRADIOL at the very beginning of my hysterectomy and had problems with it then,that being the reason I was put on PREMARIN.After 14yrs of PROBLEM FREE HRT,I have been forced back on ESTRADIOL and the problems are the same if not worse. I started getting a migraine 3 days in and have been having them on and off with a constant headache in between since. my mind is foggy all the time,I'm always from one extreme emotion to the other,and the constant hot to freezing flashes and sweats is enough to drive someone insane,not to mention the never ending food cravings! I will NEVER recommend this drug to anyone,much less anyone who is switching from PREMARIN for what ever reason! F 42 3 weeks
1MG 1X day
3/26/2016
Email
 4  sweating, v-dryness, mood swings no side effects relaxed my nerves;works for me. did not want take so happy i did. my mood improved, enjoy sex with hubby again, no hot flashes/sweating while its cold outside. F 44 7 days
1 mg
3/1/2016
 1  severe nightsweats, hotflashes I never have headaches, however as soon as I put the patch on I developed a headache. I had shortness of breath and nasal congestion which I attribute to fluid retention. So that is very uncomfortable. I am athletic and I had gained weight prior to taking the patch and I am certain that if I keep this patch on for the month I will have 30 lbs to take off. My hot flashes and night sweats have not diminished and the worst side effect which I felt immediately was an apathetic mood... depression ( bitchy) absolutely horrible! I take antidepressants and I believe this patch cancelled out their beneficial effects. Basically I have a lot of really bad side effect and no benefits , so I am not happy. I couldn't wait for a week. I ripped the thing off last night. I will find other ways to deal with this. I am scheduled for blood tests and I had her check off basically everything! Cortisol is something I believe that is having a negative effect on my hot flashes and night sweats just due to the timing of cortisol release in the blood stream. F 49 6 days
.025
2/4/2016
 4  menopause symptoms A bit tired initially. .but wonderful next day. I take alternately. Every second day. No more flashes ..and feeling normal.again 53 1 days
.05
9/6/2015
 1  Mild Menopause Symptoms.Memory loss Do not recommend this for anyone that is sensitive to drugs. I did not go in to doctor with any vaginal dryness, I only had mild menopause symptoms. My uterus felt like it swelled, felt like I might have a yeast infection, which I didn't. Nausea and belly was hard, but I was not constipated. Doctor gave prescription for 1 pill just in case I did get yeast infection from the Estradiol, but that didn't really help. Then I started to get lower back pain and cramps off an on. I haven't had any symptoms like this for YEARS! Why did I start taking this? This was only after use for one week! Two weeks later and I am not completely better! I went to another doctor they said be very careful when doing Estradiol cream!!! F 51 7 days
1mg 2X day
10/25/2014
Email
 1  HRT 41yrs old complete hysterectomy Extreme hair loss & weight gain help need something else ! Premarin 2mg makes me a big Bword ! F 41 4 months
1 1/2 pill
9/29/2014
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 1  HRT Took Premarin for 30 years. Insurance stopped covering. Insurance suggested I switch to Estradiol, which was equivalent. NOT TRUE. Had No side effects with Premarin. With Estradiol, I have severe joint pains, am lethargic, ache all over, excessively hungry, feel fat/blotted, am having continual hot flashes. F 69 30 days
1mg 1X day
9/6/2014
Email
 1  Vaginal dryness from menopause Severe bloating, pain in my abdomen, weight gain, water retention, dry eyes, and muscle pain. My gyn told me to use the Estrace Cream internally. I took two doses. The first dose I took on a Tuesday, the 2nd on Thursday. By Saturday, my abdomen felt like I had a belt on that was way too tight. I couldn't get my pants to button that are usually plenty big on me. My hands were so swollen that I couldn't get my rings on without effort. I visited my primary care dr on Monday and told him what was going on. He said that the does was way too high and just to use a tiny bit topically and not to use the plunger. He said that once the estrogen levels start dropping the symptoms should go away. The swelling in my abdomen and fingers have gone down, but my eyes were so dry last night that they were throbbing. I woke up this morning with severe muscle and joint pain and can't turn my head. Hopefully, in a couple of days, things will level out again. Amazing what fluctuating hormones can do to our bodies. F 53 2 days
2 mg 3X W
3/5/2014
Email
 1  hormone replacement Tried switching to generic estradiol from brand name Estrace, due to cost. Have tried the generic several times. Every time, within 3 days, I felt like I was losing my mind, severe anxiety begins on day 3. Also indescribable physical discomfort, loss of inhibition of the rage it caused, and very dangerous irrational thoughts and illogical thinking. This last time, due to the unaffordability of Estrace, I tried to "stick with it" as my pharamcist put it. 7 days of constantly worsening - basically - really losing my mind. I stopped and went back to Estrace and was back to myself in 48 hours. All my doctors and pharmacists, over 20 years! claim they have never heard of any reaction like this. I have tried several different manufacturers; all with same results. Please, if you start estradiol, be aware that this can happen, and it may not be connected to the drug by any practitioner, and it is in a way very subtle. F 60 7 days
1 mg/day 1X day
9/25/2013
 2  Post-Full Hysterectomy Joint pain, sever muscle aches and pain, sudden onset of anger and frustration, unable to form a thought, painful burning sensation of upper arms, difficulty sleeping, super hot hot flashes, night sweats remain. First night I took Estradiol, I woke up feeling great for the first time in weeks. Prior to the pill, I had been using the 0.5mg Patch, which was not only useless but a waste of money due to it falling off in the shower. I would have to say that the pill has to many nasty effects on me physically. I didn't have this joint/muscle pain prior to taking the pill. I'm literally in pain that not even my usual pain killer will get rid of! Time to talk to my Oncologist about a natural alternative. I skipped my last dose and feel a thousand times better. Residual pain is fading, but this stuff is wicked on my system. F 37 7 days
2MG 1X day
12/20/2012
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 4  Menopause I've noticed odd and vivid dreams. I have a bit more energy which is awesome. Noticed hot flashes are a bit decreased. I don't feel quite as outgoing. We'll see. Hopefully no depression will set in. F 51 5 days
0.05 1X day
5/29/2012
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 3  Hot flashes sleep problems Migraines, acid reflux, gas pains in chest I am also taking Prometrium 100 mg at bedtime. My Gyn instructed me to put estradiol under my tongue and let it dissolve. I have a history of migraines & acid reflux so not sure if connected to starting this new combo of meds. The gas pains in chest near heart happen once daily usually in AM and feel like something terrible is happening then it stops. F 48 25 days
1mg 1X day
11/27/2011
Email
 2  Post-hysterctomy Menopausal Symptom Constant Vaginal Discharge, Frequent Mood Swings, Depression, Loss of interest, Migraines, Cramping, Increased Appetite This medications literally makes me feel as if I am losing my mind. I have struggled with feeling hopeless, depressed, indifferent, sad, and angry within minutes of one another. I came to compare my symptoms with other women but I am having a tough time gauging since I am a younger patient than what it typical. I am very concerned with it's effects. I think I am going to try something else. M 26 3 weeks
1 mg 1X day
5/23/2011
 3  Post menopausal symptoms Just wondering if others had very vivid dreams on this F 57 9 months
.05mg 1X day
2/6/2011
 3  Menopausal symptoms Migraine, anxiety and high blood pressure I'm in the process of weening myself off of Estradiol which I hate because it worked wonderfully for the symptoms of menopause. Unfortunately, my blood pressure started to rise after being on it for less than a month. Then the headaches started until they become migraines. Also, this last month I started to get crushing anxiety to where I had severe chest pain. I had previously attributed all of these symptoms to my high blood pressure. However, after doing research and finding other women discussing these same issues, I found many who attributed it to being on estrogen. I plan on using phytosterols and other Chinese herbs and hope they will work as well as Estradiol without the bad side-effects. If they don't work, I'll ask my doctor to let me try EstroGel since it has fewer side-effects. F 52 3 months
2 MG 1X day
4/26/2010
Email
 2  I never stop bleeding None I was prescribed estradiol 2mg/day for 25 days, with the last 10 days also taking prometrium 200 mg/day. I have been bleeding almost every day for 10 months. This did not help. F 30 20 days
1/14/2010
 5  MTF transsexual hormone treatment Breast discharge, breast tenderness. I am taking this with spironolactone, which seems to counter the fluid retention and weight gain that it might cause otherwise. But the estrogen seems to counter some of the unpleasant side effects of Spiro, which increases the feminizing effects of estradiol, making for a very good hormone regimen. Wonderful! I take 2 mg of Estrofem (Novo Nordisk) sublingually (under my tongue) every evening. Causes breast tenderness, but I expect that and it does not bother me. My breast discharge doesn't really bother me either, except that I worry about it possibly being a sign of a serious side effect. Fortunately, two doctors who I have asked about that possibility say that it is unlikely. F 24 2 years
2/23/2008
Email
 4  HRT,vaginal dryness,no libido none Taking Estradiol after taking (AWFUL) Premarin for 5 years. Feeling better on Estradiol! I think I may be gaining my libido back,too soon to tell. I feel much more normal on it...Premarin was AWFUL! F 35 6 weeks
12/20/2007
 5  menopausal symptoms Lowest dose (0.025 mg) controlled symptoms just fine, no side effects. F 66 5 years
9/25/2007
 5  HRT for primary amenorrhea Breast growth, menstruation, increased sex drive, breast tenderness, light cramping, light moodiness, improved overall mood I have been diagnosed with primary amenorrhea. Taking a combination of Estradiol and Prometrium allowed me to function more normally. F 25 1 years
2/9/2005

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