Average Rating: 2.7 (53 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ESTRADIOL: Reviews Summary  |  Drug Safety Information

 3  Hysterectomy Some days extremely fatigued, strange arm pain, feel like I cannot move some days, chest tightness, some headaches. It definitely controls the hot flashes I mean like totally successful in this way and that is why I have continued to take it but I have become suspicious that it may be the culprit of my health problems. I have been weaning myself off it the last couple of weeks and I can already feel the hot flashes returning. I am going to see how I do without it awhile even if I have to suffer the hot flashes. F 53 5 years
1 mg daily 1X D
 2  Post menopausal Anxiety, mood swings and crying spells. Dry lips and thirsty all the time. The first day I took it it gave me a lot of energy and I felt like I found something that was going to work for me. But then as I continue to take it started to give me anxiety and a roller coaster of mood swings even to the point of wanting to cry. I rather have flashes than deal with the side effects. F 55 14 days
.5 1X D
 3  Hysterectomy/menopause Headache, muscle and joint pain, stomach cramps, nausea, dizziness, insomnia, bloating, indegestion, painful calfs, increased anxiety, sore throat, blocked ears with pressure, flu type symptoms, heart palpitations, stuffy blocked nose, irritated bowels and bladder, thinning hair. I started on hrt 4 years ago after a hysterectomy, I still have my ovaries was only 44 at time of starting it, it's been a long and uncomfortable journey I've never felt great on any hrt but can't put up with symptoms without it, each one I try brings a whole list of horrible side effects but to be fair if you wait long enough most subside, but I always get left with ongoing side effects it's a trade off, with that and menopause symptoms hard to tell the difference sometimes, the one and only thing it takes care of is the flushes hit and miss with the rest, I'm in uk and use everol 50, it's not brilliant but the better one I used recently tryed estradot /villedot and that was awful felt like I was dying on that gave up after 3 months and went back to everol, don't like the patch so visable and at times problems with sticking, used the gel in beginning for a year which was better but gave me constant thrush, can't win, lucky women who stick on a patch and claim its a miracle, think that's not the case for most of us, certainly not me, treat symptoms but get side effects there's always a trade off F 48 4 years
50 patch 2X W
 4  Hot flashes No significant side effects. Maybe a bit more tired and sore but this beats the hot flashes at age 67, was still having hot flashes. Enough is enough. It has been over 10 years since menopause. So sought help with gyn. We are slowly, at lowest dosage possible trying to stop the for flash cycle. .025 mg helped a lot and .0375 seems to stop them. Will jump off in 6 months to see if the flashes have stopped. F 67 6 months
.0375 2X W
 3  Hormone replacement/ hysterectomy Lower stomach cramps. Symptoms of UTI . Bloating . Headache F 53 5 years
1mg 1X D
 4  Skin and hair Great! I was on bc pills then stopped taking them mid 30s. Hair started falling out and skin looked and felt terrible. I have full think hair and look 10 years younger. Still have periods but I don't have any “ menopause or perimenopause” symptoms. Lots of energy, sleep like a baby way better than bc pill!!! Take a dose high enough to be effective. You'll know when you get it right you'll feel like you did in your 20s F 48 11 years
200mcg 1X D
 4  Follicle growth suppression Vivid dreams, bloatedness / slight weight gain Taking this drug (brand prescribed was estrace) as part of the egg freezing process. My wild dreams started about 2 days in. F 33 15 days
2mg 2X D
 3  Hysterectomy Upset stomach, nausea, puking, headache For me it seems to do alright half the time and half the time I feel sick F 29 0 weeks
1mg 1X D
 1  I had a hysterectomy in 8 months ago After taking it for six days I could not move or walk with the severe pain in my left pelvic and hip area. I literally was in a wheel chair cause I couldn't walk for the pain. And that lasted for 5 days to get it out of my system dont take estradiol. Weight gain F 49 6 days
0.5 mg
 3  Hot flashes, brain fog, trouble sle Severe headaches, vivid dreams, anger and anxiety, low libido, bloating, breast tenderness and fluid retention. Worked great for hot flashes and brain fog for a year. Seems to hurt more than it helps now. F 51 1 years
.5 mg
 1  menopause I have been using the generic estradiol cream 0.01% and have experienced a severe headache for 48 hours. I have experienced a rash on my belly which is itchy and my legs have cramped up as well. Please make a better generic estradiol! F 61 2 months
1X D
 1  Hysterectomy Did stop anything !!!Does not work F 62 6 years
2 MG
 1  Hysterectomy After using for one year, I have pain in both arms and upper neck pain as if I have arthritis or nerve pain. Its worse at night and cant lie on my side. I cant put my bra on since it hurts to bend arms. F 47 2 years
 3  Hysterectomy Watch your generics. Not all equal. Mylan generic M E5 on blue round tablet works great!! Had been on it for a year after total hysterectomy. NO PROBLEMS! Felt normal in every way. Was given green oval Teva pharmaceutical brand and had a meltdown. Felt like crying nonstop. Was crying for 2 days. Got back on Mylan pharmaceuticals blue tablet and feel great again. Watch your generics. Not all equal. F 43 1 years
 5  Hot flashes None F 61 19 years
 4  Menopause I dont have hot flashes anymore, however, the scale keeps going up and Im working out more. Ive gained 25lbs over this last year F 53 1 years
5 mg
 3  Vaginal Atrophy I have night sweats when I take it and weird dreams. I take it 2 times a week. It seems to be helping with the atrophy. F 59 4 months
3 mg
 2  Menopause symptoms Horrible back pain; some bloating. F 55 30 days
.5 MG
 1  for menopause Nausea, migraines, dizziness, chills, fatigue, chapped lips, skin dried out, brain fog, severe anxiety, aching joints and muscles, severe gastritis and acid reflux.I didn't have these problems before the pill. These side effects started about an hour after the very first pill. The doctor said to stick with it for a month, but each day just got progressively worse. These pills may be inexpensive, but I am going back to the estrogen patch. I never had any side effects from those. I switched to the pill form to save money. It was not worth it. F 52 1 months
2mg 1X D
 4  Total hysterectomy No negative side effects It's a godsend. I have energy that didn't know existed, no pms symptoms at all. I do have the occasional hot flash but no night sweats at all. Definitely know if I miss a dose, irritability and bladder spasms. F 49 30 days
1 mg

ESTRADIOL  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   (Sources: U.S. Centers for Medicare Services, FDA)