SAVELLA Reviews (MILNACIPRAN HYDROCHLORIDE)

Average Rating: 3.0 (158 Ratings)

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 Type: Rx Drug

  

SAVELLA  (MILNACIPRAN HYDROCHLORIDE):  Milnacipran is used to treat pain caused by a condition called fibromyalgia that affects the muscles, tendons, ligaments, and supporting tissues. This medication is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-01-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SAVELLACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Fibromyalgia anxiety, depression, insomnia, excessive sweating Had no effect on my joint/muscle pain caused by Fibromyalgia, so I stopped after 8 weeks. Just another SNRI that supposedly cure all ailments (depresion! anxiety! panic attacks! pain! fibromyalgia! OCD!.....doctors have no idea what the f&*$ they're prescribing, or how these drugs work. It's reprehensible. F 27 8 weeks
100 mg 2X day
3/24/2011
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 3  Nerve pain in my leg itchy scalp, insommnia, enlarged prostate, weight loss, frequent night time urination with interrupted flow. I took Lyrica for over a year and my physician recommended I try Savella because I wasn't getting much relief for the pain. I haven't seen any change in pain with Savella either but I'm getting side effects that I never had with Lyrica. M 59 2 months
50mg. 2X day
3/23/2011
 5  Fibromyalgia no side effects I have diabetes and conditions related to Diabetes, Sjogrens, acid reflux, year round seasonal allergies and Fibromyalgia. I take meds for all conditions. I started at 12.5 mg 2 times a day 7/14/10, increased to 25 mg 2 times a day on 8/25/10 and increased to full dose 50mg 2 times a day Nov 1, 2010. I wnated to introduce the drug slowly to make sure there would not be any extreme med interactions. The fibro pain has been reduced 65%. I feel better than I can remember in a very long time. F 55 4 months
50 mg 2X day
3/11/2011
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 1  fibro Took one dose of 12.5 mg and had the most horrendous headache, nausea, and depressive symptoms. Do not recommend! F 33 1 days
12.5 1X day
2/25/2011
 4  Fibromyalgia dry scalp, sometimes itchy didn't have this as a chronic problem until started taking medicine (switching shampoos helps); initially face flushed easily, not so much now. Heartbeat weird at times; vivid dreams sometimes. Nausea, but taking it after food helps; probiotics help too. I found this medicine to help. The fatigue lifted fairly quickly after I started and the numbness/pain went away. I was less angry/irritable after taking the medicine. Now if I overdo it or get sick, some symptoms come back. I have a lower than normal white blood cell count, but that is not due to the medicine. I struggled with being sick during the fall and winter and found my fibro symptoms coming back. I received acupuncture treatments weekly for a month while on Savella and my fibro symptoms went away without having to up my dose. I think Savella works but it can not work alone. Need to eat healthier - Acupuncturist said Omega-3 foods help for fibro, and have a more regular bedtime and excercise. If I do not do this, Savella doesn't work so well. But Savella did greatly reduce my numbness/pain and my fatigue and my irritability/moodiness. But in order for me not to up my dose, I had to start taking care of myself - limiting activities, doing low-impact excercise, eating healthier, and doing acupuncture. F 32 7 months
50mg 2X day
2/18/2011
 2  Fibromyalgia ringing in ears, constipation, depression-uncontrolled (depression was moderately controlled prior to taking Savella) Savella has not worked for me. It did at first, but after my body got "used" to it, the dosage had to be raised for effect (x2)and the same thing happened...worked for about 2 weeks, then stopped working. F 57 6 months
50 mg 2X day
2/18/2011
 1  fybro swollen prostate,inability to empty bladder.pain in groin would like to hear back from other people who have same effect's,would like to hear what medical pro's recomend. Am stopping dose . M 47 4 days
50mg 2X day
2/15/2011
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 1  back pain, fatigue excessive sweating, hot flashes, racing heart rate, extremely high blood pressure still having back pain and fatigue M 41 21 days
25 2X day
1/29/2011
 5  Fibromyalgia Fast heart rate, pounding heart, foot cramps It has been like a miracle drug for me. I can now function with little to no pain. Wish the side effects were less, but I will deal with that. F 50 4 months
50 2X day
1/27/2011
 3  chronic daily headache Hot flashes, flushing, heart palpitations, difficulty sleeping, weepy feeling, brain zaps seemed to help my head pain at first, side effects not as bad as other meds I've tried for headache (tricyclics, AEDs). worth a try IMO for those who have "tried everything". F 42 8 weeks
25 mg 2X day
1/26/2011
 2  Nerve pain Chest pain, Shortness of breath just walking to toilet and back, HBP, pulse rate to 109 (resting), Palpitations, constipation, foggy memory, sweating/ hot flashes, sore muscles, irritable/mood swings, It did seem like it maybe was going to help with the pain in leg and bottom of feet. Too bad I was really hoping for some relief M 55 12 days
25 2X day
1/25/2011
 5  FM 1 per day (12.5 mg)NO SIDE EFFECTS and really controlling my pain and depression. Savella is a GREAT medication AT A LOW DOSAGE. I am newly diagnose with FM (I have been treating “arthritis pain” for years) but progress to very painful "Hit by a Bus" type of pain about 4 months ago. Lyrica 75 mg stopped pain but left me feeling high and started retaining water weight. I tried Lyrica 25 or 30 mg but it did nothing for my pain. Then the doctor tried me Savella trial pack 12.5 mg – no problems, but Savella’s next white pill, I think it’s 25 mg, I started getting heart palpitations and chest pain, hot flashes and increased my blood pressure. My doctor suggested I I use only the 12.5 mg (the lowest dosage) 1 per day. It took a few days for me to start feeling better but I’ve been on 1 per day (12.5 mg) for over 3 weeks now with NO SIDE EFFECTS and it is really controlling my pain and depression. Savella is a GREAT medication AT A LOW DOSAGE. The prescription is very expensive even with insurance so my dr. wrote my prescription for 2 pills per day, but I only need it once per day. So a prescription (60 pills) last me for 2 months which is a great help. Savella works great for me at a lower dosage. Don’t give up, I know I almost did, keep trying meds at low dosages to control pain and avoid side effects. I’m feeling much better now, so I will try to start walking/exercising again. God bless everyone. F 45 3 weeks
12.5 1X day
1/10/2011
 1  Fibromyalgia drowsiness, severe hot flashes. I feel like I'm on fire inside. My muscles hurt so bad it wakes me up in the middle of the night. I can't get comfortable. Joint pain has worsened. Don't know if it's from the Savella. Just overal weak and tired all of the time. F 35 15 days
50 mg 2X day
12/19/2010
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 4  Fibromyalgia; nerve pain Had tried Lyrical with unhappy results( constipation, head spinning, sudden hair loss, bloating). Rheumy suggested I try Savella. No constipation this time ( ialso had IBS which errs toward constripation)...in fact I think I am going more often. Sometimes I get a tingly feeling in scalp. Blood pressure only pre-hypertensive when I check it at work once a day. Get occassional lightning type headache...but also have that from nerve injury due to a fall I had 2 years ago. I am not feeling as achy or least less aware that I am hurting all over particularly in my spine. I promised my rheumy I would try it for 5 or 6 weeks this time. So far...not too bad. F 57 14 days
50 mg 2X day
12/11/2010
 5  possible Fibromyalgia diagnosis My head crawls sometimes which isn't bad, just annoying. My sinus's have cleared up great. I have bad allergies and have a sinus infection 4 times or more a year but now I breathe better. I had a few nights of no sleep but started taking the meds at 7 pm and sleep is much better. I have always had a headache everyday so I'm not sure if the 2 bad headaches I had were from Savella or just my normal sinus headaches. I was in having all over body pain and aching. After starting Savella I was extremely nervous reading the side effects, especially the suicidal stuff. I am on an anti depressant and was afraid it would make things worse, but it hasn't I feel so much better. I still hurt some but the major pain and aching has gone away. I actually clean the house now and do things outside. Before starting the meds, all I did when I got home from work was lay down and nap or lay on the couch and watch tv. Had no motivation or energy for anything. So far, I have been blessed with Savella. I go to the doctor in a week to have more tests to see if I have Fibro and if I continue on this med. What ever is wrong with me...Savella has helped with minimal side effects. F 47 4 weeks
50 mg 2X day
11/26/2010
 5  Pain & Confusion from vaccinations Pill 1: - Intense ringing in ears at times. - Diarrhea - No pain relief - Scalp tingles - Right side burns Pill 2: - No ringing in ears - Right eye blurry - Feels like things are not being processed correctly from my right eye/ear - Scalp tingles - Diarrhea - Right side burns - No pain relief Pill 3: - Diarrhea - Ringing in my ears - Right eye hurts and is blurry - Scalp tingles - No pain relief Pill 4: - No Diarrhea - No ringing in my ears - Scalp tingles - Some pain relief - I smiled a few times and actually meant it Pill 5: - Diarrhea - Still have tingling in my head - Still have neck pain Pill 6: - Diarrhea - Still have tingling in my head - Still have neck pain Pill 7: - No Diarrhea - Still have tingling in my head - Still have neck pain - Have prostate pain now too - During intercourse, had ejaculations of prostatic fluid several times before finally having any orgasm and release of seminal fluid Pill 8: - No Diarrhe M 33 6 days
25 2X day
11/8/2010
 4  Phantom limb pain Side effects are quite unpleasant. I have to take Atenolol to lower my heart rate now because the Savella increased my resting heart rate to 115! I have also had low to normal blood pressure. Without the Atenolol, My heart races with the slightest exertion. Also, I have testicular pain. My doctor confirmed that this is a side effect of Savella. I also have trouble draining my bladder while taking this drug also unpleasant sexual side effects.. There are This is the only drug I have ever taken that actually controls phantom limb pain. I do not like the side effects, but I put up with them because they are better than the phantom limb pain. M 54 2 months
100mg 1X day
11/4/2010
 3  FibroMyalgia Severe hot flashes that caused such terrible perspiration as to drench my hair and clothes. Itchy painful rashes wherever I perspired; terrible dry mouth; constipation; dizziness to the point of falling over even while sitting down. It worked to eliminate the pain and "fibro fog"; but the side effects were so ghastly as to impair my ability to do my job. Diagnosed with FM 12 yrs. ago, I am now trying to taper off of this and my dr. will try something else. I still feel terrible and am so saddened that it didn't work for me. F 55 8 weeks
100 mg 2X day
11/4/2010
 4  Fibro Myalgia Started at 12.5mg/2day.... vomited middle of the nite increased to 25mg/2day.... woke with slight headache 3 days increased to 50mg/2day.... slight decrease in appetite Getting up to quickly causes dizziness, very dry mouth, more sweating, shortness of breath off and on I believe I am feeling better overall although I still have chronic pain from a car accident AND I was recently diagnosed with Lupus on top of the Fibro. I take vicodin with the Savella and it really does help I think.... it is only 12 days so it is very soon to tell. The doctor told me to stay with it even if the side effects were hard to manage at first.... she said to try the titration pack for a full 2 week before I decide the side effects aren't worth the benefit. I'm glad she encouraged me to stay with it because if she didn't - I would have given up after the first day. Will post more as I progress. F 54 12 days
50mg 2X day
10/11/2010
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 3  Firomyalgia Headache, vomiting, mood swings at each increase of dosage. After about 6 month on drug BP rose to high Dr. tried to down dosage but it kept going up so I needed to stop - worseside effects going off F 50 8 months
100 2X day
10/4/2010

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