SAPHRIS Reviews (ASENAPINE MALEATE)

Average Rating: 3.4 (131 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SAPHRIS  (ASENAPINE MALEATE):  This medication is used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Asenapine helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there) and prevent severe mood swings. Asenapine is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-08-13 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SAPHRISCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Bipolar II I experienced a tremendous amount of anxiety while taking this medicine. It also caused me to have hypomania which I had never had before. F 42 31 days
5 mg 2X day
3/16/2013
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 1  Major Depressive Disorder/Psychosis I HATE HATE HATE THIS DRUG!!! THIS DRUG MADE ME HATE ALL OTHER ANTI PSYCHOTICS INCLUDING LATUDA( WICH I TOOK TOO) I had the black cherry flavor and i waz excited to try it and right away my tounge got numb and the flaver waz bitter but not bad. I couldnt go to sleep at all and hours past and lets just say.......... the akasthisia waz the worst ever it waz worse than tearing my ACL and im not kidding!! I waz crying and I tried to get up and walk around but i couldnt coz i felt like I waz under anasthisia!!! I waz stummbling and I waz just beggin for it to end! like 50 hours later i fell asleep. when i woke up i had a bad surprise, I waz soo drugged it felt like I waz under anasthisia. Like when u get that sensation when ur goin under, yes.I woke up at 8am and it lasted until 7pm. I called my pych doc right away and she wanted me off it and try Latuda that night ............... and thats another nightmare for later! lolol Soo it was my first day ever goin to a psychatrist and she told me to take Saphris first and if that doesnt work next day take Latuda. She never told me they were anti psychotics........ who does that?? I'm glad im over Saphris. Latuda waznt much better on 40mg but now im on Lamictal and its amazing so everything turned out ok :P F 18 1 days
10 1X day
1/24/2013
 5  Bi-Polar I with mixed episodes This medication work after the first night taking it. It helped me sleep, but more importantly, helped decrease significantly my severe agitation and irritability. The taste of the medication is fine. It numbs the underside of your tongue a little, but you get used to it and the numbness goes away in a few minutes. Would definitely recommend this medication! F 40 3 days
10mg
12/29/2012
 5  mood stabilization No side effects, except irritability if I miss a single day. I'd call it chemically addictive. F 28 2 years
10
12/23/2012
 5  bipolar disorder a little sedation M 40 30 days
10 2X day
12/14/2012
 1  hypomanic episode with mixed states Inability to swallow 20 minutes after first dose. Lasted about an hour. Took only at bedtime after that. Helped me sleep but did not help with agitation or hypomania during the day. Switched to Vistaral after 10 days. Next day extreme aggitation ending with suicidal ideation and crisis unit stay. Not sure if one dose of Vistaral or stopping Saphris caused the suicidal ideation, but it resolved in a couple of hours. F 48 10 days
5 mg
10/24/2012
 3  Bi-Polar II- depression and anxiety This medicine has helped me somewhat with depression. I think I need to up the dose though. I may need to take something with it for anxiety, but I'm not sure. This medicine can make you restless. I don't have the restless leg thing, but I do get an inner restlessness if I don't take it with Inderal. I've heard you can also try taking Saphris with a drug called Cogentin to combat the restlessness. Other than the agitation, numbness of the mouth after taking it, and the unpleasant taste, I'd say this drug is pretty good. F 34 1 months
10 mg 1X day
10/6/2012
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 4  major depressive with voices tried saphris for 2 weeks and it helped my mood and voices. i stopped it because of the restless legs and a little anxiety and went on latuda, but am going back . i felt a lot better on saphris F 46 2 weeks
5 1X day
9/17/2012
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 5  Bi-polar with depression When I first starting taking Saphris at the recommended dose, it made me very hyper and alert. It felt like I did some speed, and I was a ball of energy. After a full week of that we cut back to 5mg for the whole day. Still too much, put me in a maniac spending spree. After several weeks, we went down to 2.5mg a day and for the last seven months, I am doing fabulous. The perfect dose for me was not the recommended dose and never is. I am very sensitive to the normal dose that most people take, other then that I have no bad side effects only good. I have tried a lot of different medications over the years like, Celexa,Lexapro,Lamictal,Neurotin,Depakoe,Trileptal,Cymbalta,Wellbutrin, those are the ones I can remember anyways,and nothing has worked has well as the Saphris has. I have a lot of Anxiety and so with the Saphris, I also take 0.5mg of Klonopin once or twice a day as needed and 100mg of Wellbutrin Hr. I have no suicidal thoughts anymore, it made my stomach issues go away I don`t get depressed like I use to once a month. Thank you, Thank you, for this wonderful drug you made for us bi-polar people. I have never felt this good in my whole life before and I owe it all to my Doctor and to Saphris. F 59 8 months
2.5mg 1X day
6/17/2012
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 5  Bipolar I - ADHD spectrum Loss of taste plus a "Jack Daniel's 5th and Smoker's Morning Mouth" all day long. I neither drink nor smoke. Step 1. Press tab round side flush into membrane under tongue. Step 2. Stick tongue out a minute or two until tab is absorbed. I learned the "stick your tongue out" trick on this web page. THANKS! My taste buds are back and I only have a moderately uncomfortable tongue sensation. It feels a bit like I have burned my tongue with hot coffee. Saphris gave me back myself for the first time since 2003. I am off Seroquel. Fabulous. 50 mg per day methylphenidate (Ritalin) dose is down to 0-10 mg per day. I wake up refreshed even with my nightly 50 mg of lamotrigine on board. M 61 7 days
5 1X day
6/12/2012
 5  Bipolar (mixed episodes) Numb tounge after taking it. Tiredness. If I take 10mg once I get Rls. Get really hungry after taking it..obsessive thoughts about food. hah This medication is amazing but if I miss a dose I regret it. It really stables me out. The crying spells and extreme irritability is gone. No racing thoughts. I also suffer from horrible anxiety and this helped tremendously. It did make me gain weight in the beginning but really I take it at night and just refuse to eat so I dont gain weight. Or if I am just to hungry to sleep I'll drink a protein shake. This drug has given me my life back with little side effects. I've seriously tried almost everything out there my doctor was running out of options and he put me on this and it was like a miracle. I finally feel normal and I can function. If I'm having a real emotional day or feeling very stressed then I take a half of a 5 and feel so much better in 30 to 45 mins. This drug is amazing. I never want to get off of it. It just sucks that it cost so much but well I'll pay that price verses being on medications with a ton of horrible side effects. LOVE IT! And on a side note, I have a horrible time with medications because of side effects. This is the first one that I can be on and its all bearable. F 23 2 years
5x1 1X day
5/17/2012
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 5  Bipolar 1, mixed, rapid cycling I went on this drug when I could no longer take the weight gain related to Zyprexa. I had heard from my psychiatrist Saphris was molecularly similar to Zyprexa but without the gargantuan appetite side effect. I am glad I switched. While Saphris does give me a sudden urge to pig out, this sensation lasts just 15 minutes and then the drug knocks me out for the night, whereas Zyprexa would boost my appetite all day and night. Saphris has helped me feel calm and even more spiritually connected. My only complaint is that it makes sleep come rather suddenly -- I don't "drift off." And I sleep 8 hours no more, no less on it. Had to get back on coffee to clear the morning drowsiness of this drug, but all-in-all I am very happy to have made the switch. I am now in a weight loss program to lose the Zyprexa poundage, and I feel like I have my life back. There is an unflavored and a black cherry version of this drug. insist on the black cherry and make sure the doctor writes this on the prescription or the pharmacy might fill with the regular stuff. The unflavored type tastes like plastic that has melted in the dishwasher. The black cherry flavor is no cakewalk but is still 70% more pleasant. F 34 2 months
10 1X day
4/23/2012
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 3  Bipolar 1 Disorder Numb tongue for about 1 hour... Im not sure if its the sun or the Saphris- but i feel a little better! Ive gained alot of weight using this drug! I also get the munchies really bad at night from it i think??! F 27 7 days
10 mgs
4/6/2012
 5  Schizoaffective Numbing/burning of tongue, extreme sleepiness about thirty minutes after taking it, re-charged sexual ability. The black cherry flavor makes this medication so much more tolerable. Sleep is great with it and not too much of it either. Wake up refreshed (no hangover). Feeling about as close to my ideal "normal" as ever. No sexual problems... if anything, libido has increased and it's enjoyable. No weight gain so far either. Just wish this came in regular pill form as I don't care for the numbness and burning feelings that come with taking it. M 39 6 months
10 mg 1X day
4/4/2012
 4  Moods This medication works great. The only thing I dont like is the tast. It helpd my moods greatly. This is a mirecal drug. F 20 4 days
10mg
3/26/2012
 4  Schizophrenia Sexual. Almost no libido, but sexual performance is adequate. Lost weight on this drug after coming off of low dose of invega plus low dose of zyprexa. We are getting very close to side-effect free medication, the libido issue is pretty much all that remains at this point. Might I add that this drug is better for the schizophrenia itself rather than Zyprexa, overall, a major improvement. I read somewhere that this drug s chemically similar to Zyprexa, so it may be a good option for people that want to wean themselves off of Zyprexa. Wish thy had this when I was about nineteen, then again, people would have been grateful had Zyprexa been around n the seventies and eighties, so who am I to complain. M 38 400 days
5mg 2X day
3/20/2012
 4  Bipolar II Bitter taste and numbness with the black cherry but tolerable. The first night I took 5mg and the next morning wasn't good but the next night I took 10mg as my doctor suggested and wow! I've been doing good so far. I will periodically update my reviews if anything major changes Some say weight gain but I'm not hungry on this so far. I already take lorazepam .5mg 3x per day, 20mg Prozac started when I started Saphris so that could be helping too. I also take Keppra 500mg 2x per day, vyvanse 70mg per day, temazepam 30mg at night which I still need apparently. Saphris isn't knocking me out like others have reported. I also take flexeril for my back 10mg 3x per day. So far so good! My doctor said its known as the new and improved Seroquel without the weight gain but its only been five days. Seroquel put 50lbs on me over five years so about 10lbs per year. I've never been this heavy so I hope Saphris doesn't do that to me. F 42 5 days
10mg 1X day
3/11/2012
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 1  bipolar 2 Tongue numbness, terrible rls & Ambien-like reaction while unable to sleep from restless legs My 1st dose of 10mg black cherry flavor: tongue/mouth numbness and bitter taste were tolerable. Within an hour was on verge of sleep but got terrible restless legs. Took 1mg Requip but didn't help. Legs were driving me nuts and was up walking around feeling like took Ambien. Really wanted to eat somethibg, but thankfully must have been aware enough to not use the stove or oven. After about 2 hrs of drifting in and out of sleep bc of the restless legs, took another Requip and was up and around again with the Ambien feeling. Drifted in and out of sleep for 2 more hours bfore finally fell asleep. Has anybody else had the Ambien-like reaction? Took on Thurs. and will try again til Mon. If still have rls and Ambien stuff, calling psych. 1st thing Mon. am. F 41 1 days
10 mg 1X day
3/8/2012
 5  Bipolar 1/ mixed episodes and mania Numbing of the tongue and mouth. Dizziness upon standing. This drug has been a Godsend for me. The noise in my head is quiet, and has been from the first dose! Anxiety has diminished to a manageable level. F 34 6 weeks
7.5 MG
3/4/2012
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 5  Became extremely suicidal. Taste horrible, first night I slept probably 14 hours, I still sleep 12 after being on it for two weeks, any sexual interest has went out in the window. As much as the side effects I had were no good, point blank Saphris saved my life, I was planning and buying supplies to commit suicide one day, took Saphris and woke up feelings 110% different, no suicidal thoughts whatsoever, mood elevated extremely, it really was night and day, I've never taken a drug that acted to quickly and I've taken about all of them. I'm on day two of not taking it because I just couldn't deal with the no sexual feelings or want's at all, I'm an attractive 28 year old guy and can not live my life this way. It's weird, I look at women the same, but just can't work up to actually acting on it. I'm not on day two of not taking Saphris, I'm not suicidal anymore but the insomnia is insane and also stiff muscles in my lower left arm, I may go back on it because it did bring new light to my life, I haven't decided yet. M 28 2 weeks
5 MG 1X day
2/27/2012

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