SAPHRIS Reviews (ASENAPINE MALEATE)

Average Rating: 3.4 (131 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SAPHRIS  (ASENAPINE MALEATE):  This medication is used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Asenapine helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there) and prevent severe mood swings. Asenapine is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   FDA Approval Date: 2009-08-13 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SAPHRISCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Schizophrenia Tiredness, Numbness Agitation I was prescribed Saphris after a number of my medicines did not work for my hallucinations. Saphris has helped. The only complaints I have is the really bad taste when you take it and the numbness of your mouth. It can make you agitated when you start it but it went away when I increased the dose. M 18 60 days
10 mg 2X day
9/26/2014
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 5  BiPolar II, Depression, PTSD Increased appetite right after taking the medicine, weight gain, numbness in mouth, sleepiness. THIS MEDICINE HAS SAVED MY LIFE!! I no longer have the constant negative dialog running through my mind. Yes, I WAS suicidal. Saphris has also helped with the depression and the inability to concentrate. Since taking this medicine I am now able and look forward to the simple tasks of my day; housework, paying bills, cooking, lunch dates with my girlfriends, and I am now even volunteering in my granddaughter's class every week. I am able to get out of bed now and do my hair and make-up after showering because I want to and not because I have to. This medicine tastes horrid; very pungent like a fermented grape seed, hence the numbness. And you have to allow it to dissolve under your tongue and not drink or eat anything for 10 minutes. It has caused me to gain some weight but I don't care; at least I'm still here. A little RLS but it subsided. Hopefully the weight gain will subside as well. Thank God for Saphris! F 52 3 weeks
10 1X day
9/24/2014
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 1  Bipolar Tardive dyskenesia of foot. F 28 2 days
5mg 1X day
9/24/2014
 1  Bi-polor2 gad i do not like this drug...it has made me very angry, agitated, have confusion and feeling not really good on this med at this point...i called to get off of it and im told i have to take it for another 3 weeks till i see the doctor even though its having bad effects on me clearly... Would not recommend M 35 10 weeks
15mg 1X day
7/21/2014
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 5  bipolar Constipation bloating F 37 10 days
5 mg
7/15/2014
 5  Schizoaffective Bitter taste in mouth. Numb tongue. Fall asleep after half an hour of taking it. I have had the schizoaffective disorder for 48 years and have tried 8 different antipsychotic drugs. This is definitely the best I have had - it is wonderful! M 69 2 years
10 MG 1X day
5/18/2014
 1  Bipoar Sudden low platelet count after 6 months of use. Rare side effect that can show up even after long term use. Beware. Always monitor your body. Seek immediate medical attention if you develop what looks like a rash and bruises for no known reasons. I also experienced nose bleeds and huge blood blisters in my mouth overnight. Very low blood platelets can be fatal or cause irreducible damage. F 50 6 months
5 mg
4/27/2014
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 5  Bipolar Disorder II/ Mixed Episodes Extreme drowsiness at first which has gotten better with time. Reduced down to 10 mg. only at night and that helps to function in the daytime better. Increased hunger and I gained 30 lbs. in 3 months but now taking Topamax to even that out. But the mania is gone and I feel normal for once in my life! It's a wonderful drug! F 42 5 months
20 mg.
1/2/2014
Email
 1  racing thoughts Was absolutely horrible. Caused voices and anger. I never want to see this drug again. M 29 6 days
5 2X day
11/18/2013
 1  schizophrenia drowsiness, inability to keep eyes open, inability to concentrate, inability to be alert. M 22 4 months
15 2X day
11/11/2013
 3  Borderline Personality, Depression This drug made me feel so much better almost immediately in terms of feeling better and less depressed (the opposite of any other antipsychotic I have tried!). Got restless legs to start with which settled with Cogentin 2mg administered just before I took the Saphris. You even get used to the taste! However major increase in appetite was too much for me. This drug is definitely worth a try for a range of symptoms. The deal breaker for me was the hunger, both immediately after taking it but also leftover hunger effects into the next day. I gained heaps of weight in a short time-frame! Its a shame as not everyone on here has had that effect so I was just unlucky! F 46 3 weeks
10mg 1X day
11/3/2013
 3  depression/ bipolar CONSTANT SEVERE NIGHTMARES. 10 MG was too much for me and made me very irritable and depressed. This medication has been the only medication of many to actually help with my depression. I feel functional on it. If I accidentally skip a dose the next day I am really depressed. Before this med I would have suicidal thoughts daily. I barely had nightmares before this med somehow put up with it for so long then started a med to help with nightmares but it didn't work at all. The nightmares I have are severe. Hellish. Demonic. I have placed an order for Latuda today as I cannot stand the nightmares any longer but Saphris worked wonders for my depression. Hopefully Latuda works the same without any nightmares. F 22 10 months
5 MG 1X day
10/1/2013
Email
 1  depression Was not on this Med past the first dose I was sick to my stomach from the moment I placed it under my tongue. I spit it out immediately. F 61 1 days
3mG
9/20/2013
 5  bipolar 1 Well i was on the verge of taking my own life bc i was sick of being so depressed and having manic episodes that no other med could help. I have been on just about every mood stabilizer and depression med known to man. I feel like a new person! I feel great!!! I feel like my life has been given back to me. I have energy and I'm so happy! Haven't felt like this in about 2 decades! F 35 5 days
2.5mg
9/8/2013
 5  Depression Happiness F 45 6 days
5
8/29/2013
 5  Bipolar I would recommend saphris to take with a mood stabilizer. I used to be only on 150mg of lamictal but that sent me into an extremely bad low. I had a migraine for a week straight, was extremely exhausted no matter how many hours I slept, fell asleep every where, and of course, wanted to kill myself. Saphris 5mg was prescribed to me and it started working the next day. It's been great so far. I'm not feeling any rapid cycles and have been sleeping well. I did skip a pill which caused me to take two throughout my day (morning and night) which was not a good idea because my mood changed for a day or two. At first I was extremely lethargic after taking saphris. It was not a good feeling, I felt extremely high. But it went away after two or three days. Saphris saved my life, I completely recommend it. F 19 3 weeks
5
6/15/2013
 4  Depression, insomnia, anxiety Bitter taste, lethargy, massive hunger attacks to begin with This drugs zaps me to sleep. I am also talking amitriptyline and clonazepam for the same symptoms, but they were simply not putting me out. I've had insomnia all my life. Saphris cured it from day 1 and at the start, the quality of my sleep was also improved in that I awoke with more energy. Over time, I've become more lethargic although Saphris still knocks me out cold. Every night. It seems to have had little overall effect on my depression or anxiety, though. In fact, my social anxiety seems to be worse. The carb cravings have gone, finally, though it tough the first month. M 43 2 months
5mg 1X day
6/3/2013
 5  borderline personally disorder Drowsiness, 10 minutes of mouth numbness M 30 1 months
20mg
4/30/2013
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 5  Bipolar/ Mixed episodes Fatigue. Shakey hands(off and on and only lasted for 2 weeks). Limbs fall asleep for a few minutes some times. Some trouble falling asleep. I take saphris a half hour before I go to bed because even 5mg knocks me out. A little sleepy in the morning, but worth it after the good night sleeps. My shakey hands went away after 2 weeks. Once in a while my arm or leg might fall asleep but not for long. No cognitive side effects. **DON'T DRINK ALCOHOL** My experience: 4 beers with friends, I didn't feel the alcohol but I did pass out on the toilet. Also I took 20mg for 1 week and was miserable. I felt extremely restless. 15mg is golden for me. No mania, no hypomania, no rapid cycling, and I still feel like myself! F 25 2 months
15 1X day
4/26/2013
 1  additional medicine for depression tongue numbness, dry mouth, racing thoughts, mania, irrational thoughts, hallucinations-physical and auditory, seizures. Worst experience of my entire life, and I have attempted suicide. Within the first few days I reached a scary level of happiness. I began to have racing thoughts, talking fast and being completely irrational. Soon after I began hallucinating that I knew every stranger in a different from school or work all day. I had the cops called on me for having a breakdown over thinking my dead grandmother was still alive to a woman and the ambulance took me to the ER. There I exclaimed to the entire ER to listen to me because I was Obama (I'm a white girl), had a seizure, risked falling into a coma, and stayed in the psych ward for 2 days when recovered. All because I took Saphris that was prescribed to me. It was terrifying and life altering. F 24 8 days
5 mg 1X day
3/24/2013

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