Average Rating: 3.4 (127 Ratings)

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Compare SAPHRIS with similar:

 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 2  BPD I tried this instead as Zyprexa practice her to see if I could not eat as much. It did help with the not eating as much but my depression and sensitivity to hot and cold has increased I also feel as if my anxiety has increased I started this medication in order to wean off of benzodiazepines are use for sleep. After taking the medication at night I maybe went to sleep for 30 minutes then I am awake all night long even with 3 mg of Ativan and 3 mg of Lunesta I cannot sleep. I just want to lay in my bed with the heat blanket on and do nothing and no motivation no help with depression sometimes I don't cry if that's the only due to the dullinf factor of the medication. The first day I took it I felt great and like my old self it just did not work after that. I think it could be a good alternative zyprexa but Zyprexa seems to have a built-in Antidepressant effect. F 37 15 days
2.5 1X D
 3  Insomnia Memory loss (short & long term). Racing thoughts and inability to concentrate. Walking less. Eating more. In a constant fog. I slept 11 hours on 10 MG. Very expensive copays. I reduced to 5MG and now sleep 7 hours. I added 100 MG zoloft at bedtime and I'm better now. M 61 4 years
10 MG 1X D
 5  Bipolar 1 Dude! Best medication out there. I was on it for 3 years until my grandma died and it stopped working. I didn't feel like working out for the first year but and maintained my weight. I then worked out religiously and lost a pound a week with diet. F 34 3 years
10mg 1X D
 5  PTSD. Bipolar. Tastes bad but u get used to it. Mood stabilized but depression increased or became more noticable. Been taking saphris at max dose for about 5 months. 6 months total. Mood definitely stabilized and I get upset less easily. Able to sleep and not wake from bad dreams all night. My depression symptoms and motivation are at an all time low. I feel it's just that I'm more aware of the depression that I've had for along time. Now that I can think clearly and my mood isn't manic. I will be seeing my dr tomorrow to discuss adding another mood stabilizer for the depression. I'd be on a antidepressant but the last 6 I was on made me suicidal. M 29 6 months
20mg @ Nig
 1  Schizophrenia Difficulty breathing and talking. Akathsia. Nausea. A sample from the psychiatrist. Blame the psychiatrist. Just say no! F 37 1 days
10 1X D
 4  Bipolar disorder 1 Increases appetite, increased weight, temporary sedation, increased memory, increased verbal fluency, lower attention, reduced impulse control, elevated colesterol, elevated glicemia Bad taste, but exelent for depression, and even better for Mania. HORRIBLE withdrawl. F 22 10 months
 1  Schizophrenia I was lied to by my psychiatrist when she told me I would experience NO side effects. I was a little scared and paranoid but I trusted her because I always had good loyal doctors in the past. Once I was in bed, I put the black cherry flavored tablet under my tongue and waited for it to dissolve. The taste was ok. I didn't mind it. Soon my tongue went slightly numb but it didn't bother me. I don't know how long it took but suddenly I was hit with extreme Akasthisia. It was so painful that it made me cry and I was rocking back in forth in my bed, moaning in distress. I wanted to get up and perhaps pace but when I tried getting out of bed I fell to the floor. I was so sedated that I couldn't even stand. I got back into my bed and put my headphones on to full volume. It didn't even hurt my ears because of how sedated I was. I was actually praying to God and asking him what did I do to deserve this? I kept repeating the words, "please just kill me. I can't take this pain" over and over. I just wanted to go to bed. It took over 2 hours for the saphris to finally knock me out. I had normal dreams and didn't wake up until the morning. For the whole day I was slightly sedated and tired. It didn't end until 7pm. This drug was hell for me. I've had bad experiences with all my antipsychotics but when I lowered the dose, I could manage again with manageable side effects. I hope your psychiatrist doesn't lie to you like mine does. It's because they want you to take it. They don't F 0 days
 4  Schizoaffective Disorder Drowsiness, dry mouth and tongue/mouth sores the first few weeks Saphris works great for insomnia and controlling episodes of hallucinations, delusions, and mania. The dry mouth and tongue/mouth sores went away after a few weeks and during that time I used oral care products designed for dry mouth symptoms. The black cherry taste is not bad - in fact, I kind of like it. F 2 years
1X D
 5  Bipolar Mania RLS, drowsiness (pretty sure that's intended), bad taste PRAISE THE LORD FOR THIS MEDICATION! I can function. I can sleep. Did I mention I can function? I gained 100 pounds on Seroquel, I was a waking zombie on Lithium, I've tried Abilify, Wellbutrin, Lamictal, and more. My single greatest fear right now is that for some reason they will stop manufacturing this wonder drug. I have never before hit the sweet spot of both feeling like me and being able to not only function but thrive! If you're considering taking Saphris for bipolar mania, I would say give it a try! You know, as directed by your doctor, but seriously, I didn't know it was possible to be both functional and myself until now. I wish that I could hack websites for the single purpose of rating this medicine higher than 5/5. F 34 7 days
10 mg
 1  For Anxiety I forgot my name, had irregular heart beat, ended up in an ambulance to the ER,where a Dr told me NEVER take it again I would not recommend this medication for anxiety F 2 days
 5  type two bipolar,depression the horrible taste is easily avoided in my experience by sucking up every last drop of spit before taking the meds, putting it under my tongue then not moving my tongue one bit for ten minutes, then taking a big gulp of pepsi. Weird but it works. My energy levels have pretty much tripled while my mood has been remarkably clear and calm. Hasn't been very long but I'm almost worried this is my first manic episode. I feel like I'm on vyvanse without the heart rate and jitter problem. I have been operating without much caffeine on a level that used to take two monster energy drinks... I'm also taking 75mg of effexor xr, which I've been on for over three years and have never felt this great in my life. I'm not anxious, I'm productive and organized. I feel ambitious. F 26 3 weeks
5 2X D
 5  Depression and anxiety No side effects so far!!! Really excited about this drug Dont like the taste but i feel refreshed after taking 2.5 mg last night and this morning. My mind is clear and focused, i dont feel hunger like the zyprexa does. I feel calm and peaceful. Hope it stays this way!!!! F 39 1 days
 5  Bipolar depression It does knock you out, so I normally take it during wind down time with my family so when we're finished talking I go to sleep. I get at least 7-8 hrs of sleep and wake up refreshed. I switched to Saphris after gaining 40 lbs on Abilify. I'm not hungry all the time. And don't late night snack anymore either since I'm sleep. F 36 9 months
5 mg
 4  Bipolar weight gain Saphris has been great for me except for the weight gain. Even with regular exercise I've added almost 20 pounds. Like others have reported it can knock you out. I take it at bedtime and sleep well. In the beginning I had the reported numbness in my mouth after taking Saphris. I no longer have that sensation. I'm very intolerant of medication and only need the pediatric dose of 2.5mg and only one time per day instead of the recommended twice a day. Even with the weight gain (which my pdoc is concerned about and attributes to the Saphris) this medicine has been a God send for me. It has helped me stabilize. F 57 10 months
2.5mg 1X D
 1  drug withdrawl and long term PTSD ok most mention the taste being not to their liking..weight gain..tiredness..dry mouth..etc. I was in a ward for 5 weeks doing a supervised medical detox from prescribed oxycodone. I was prescribed,sight unseen,zypreza. when I reported to the Dr I didn't like spread zytis I was given the saphris. what I saw during those 5 weeks confirmed all the bad press I had found about antipsychotic meds all along. off label use is common and it appeared most if not all these patients took saphris or it's chemically related zyprexa. I saw a disproportionate number of obese or generally poor physical fitness. there was an unusually high number of patients with diabetes. most appeared unemployable in the common sector. I saw that most were on multiple public assistance and non profits. i have had exposure to veteran atypical antipsychotic drug patients in the past and it's very noticeable that these people's whole system has been altered making it hard to determine if it is their illness or the drugs they take that make such people stand out. most die in middle age. be it the staring or it's more pronounced buggy eyed look or the stiff and slow movements these people acquired from common mental health drugs, the tradeoff must be enormous. I know prescribing me a mental health drug was requisite to justify keeping me on a locked psych ward so I could be slowly weaned from my narcotic drugs. the benefits of saphris, as in the use of any antipsychotic medication should outweigh the enormous risks inherent to such therapy. in my personal case it was not. M 59 1 days
 1  Bipolar disorder Out of control fits of rage. I feel angry a lot, but I have never lost control of it before. It's like my inhibition evaporated. Terrifying. F 45 2 days
 1  Bipolar-depression I have tried so hard to weigh out the benefits of this medication! For sure like others it knocks you out and helps you sleep, but when you wake up you feel like you have the worse zombie feeling hang over ever! I can't focus or keep anything in line. My family says I seem to be better because I'm not always in a rage but it's a everyday struggle to even stay awake. And do daily tasks. I've gained 10 pounds and that's because I'm ALWAYS HUNGRY, but have zero energy to do anything! I know know why the side effect would be suicide because people would rather die then fill the way this drug makes you feel. Going to the doctor in 2 days to see what else helps. After taking the same antidepressants and mood stabilizer for 8 years I don't feel this was a fit at all! F 36 4 weeks
 1  bi polar Nausea, stomach pain, zombie like, felt more depressed mostly I found this drug terrible. I have been off it 1 day now and it has ruined my natural sleep pattern. I got a lit of increasing stomach pain and nausea each day I took it. I would sleep at least 12 hours a day and when I did wake uo, it would take ne around an hour to get out if bed....and when I did I had no balance, felt like I needed to sit down a lot and could barely keep my eyes open. And it also tastes disgusting and made my tongue numb. I felt like I got a lot lot mire depressed over the 8 days I took it M 37 8 days
 1  bipolar1 mixedtype psychotic episod On it I "passed out and blacked out" the 1st & only time I ever took it. About 45 minutes later I barely made it over to my couch and then I lost the next 24 hours. During that time I am told I had 3 phone conversations I cannot remember at all. I am no drug lightweight, I am a good size adult female, have been taking various psych meds for 25 years and can tough them out usually but this one kicked my ass. I gave all my free samples back and I will never take Saphris again. If you are starting it I highly recommend you do not be alone when you first take it. In the words of Clint Eastwood I guess you have to ask yourself if you feel lucky. Maybe it's just personal preference but I don't like the idea of taking something that instantly dissolves on your tongue. No way you can puke it back up or even spit it out if it hits you wrong, plus it made my mouth feel weird. Also they say not to drink anything for a certain amount of time after you take it and I didn't like that either because I'm always thirsty from my meds. If Saphris helps you that is great; however, this Rx and I did not get along. I felt like it could have killed me. If I wanted to be a zombie I would rather just stay psychotic. God knows what damage I might have done or had done to me while I was in a blackout from it. F 60 1 days
 1  Schizoaffective Disorder Massive weight loss, grogginess, extreme chest/admoninal pain, vomiting, I also felt like I changed and became weird in my thoughts and interactions with people Tastes really bad.....but should help you sleep if you have trouble. I found this drug s mind fuck and I ended up in emergency ward 3 times from the pain I got. M 37 1 years

SAPHRIS  (ASENAPINE MALEATE):  This medication is used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Asenapine helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there) and prevent severe mood swings. Asenapine is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).   (Sources: U.S. Centers for Medicare Services, FDA)