SEROQUEL XR Reviews (QUETIAPINE FUMARATE)

Average Rating: 3.1 (142 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL XR  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). It is also used with other medications to treat depression. Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2007-05-17 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUEL XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Bipolar 1 anxiety and depression Hungry, going to the bathroom more, extremely tired...feel hungover in the morning I was wondering if anyone has felt like their lips were numb...I'm just worried its a combination of my meds...I'm on trileptal, abilify, lamictal, and concerta along with now the seroquel xr F 33 4 days
100 mg 1X day
1/28/2013
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 3  Bipolar/Anxiety Disorder Was on abilify and it lost effectivness so I was switched to Seroquel XR. Weight gain and involuntary muscle tighting and movement have been my biggest issue. I really like the way this med has improved my moods and anxiety. However I'm not sure I'm willing to continue due to the weight gain and involuntary muscle movements. They are very distruptive when trying to sit still. Hopefully my dr will have something to help with this 2 side effects that I'm not sure I'm willing to live with. F 33 5 months
300 1X day
1/28/2013
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 3  depression/anxiety/ocd extreme exhaustion Lately, I have been feeling EXTREMELY tired on this drug. I could literally sleep my life away on this! UGH! I find myself sleeping from 12 am - 1 pm the next afternoon and could STILL use a 3-4 hour nap during the day! F 26 3 years
150 MG 1X day
1/17/2013
 3  PTSD, Bipolar, Depression IRRITABILITY! It's intense, comes on in a flash. I want to do serious damage, have urges to hurt myself, and have no cause or idea why, and is totally unlike me. I hate it. Also, stuffy nose 24/7, weight gain (food cravings), mood swings. (Note: I also started Prazosin, Hydroxyzine, and Naltrexone around the same time. Hard to say what SE's are due to what.) Sedating. Intrusive thoughts are almost completely absent, where they were once a daily event, sometimes all day. The mood swings are intense but include really joyful spells, which is fun. I had no joy at all, before. Just flat. Nothing. Great motivation to do stuff, again. It's like I care about stuff more. Whereas I was totally "uh huh, whatever," before. Seroquel is definitely sedating. Which is a good thing, for me. Sleep is my friend. F 39 4 months
125 MG 1X day
12/17/2012
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 4  Bipolar 1 mixed episode/sleep Initial weight loss, now weight neutral. Grogginess in the morning (sometimes not that bad, other times to the point of not function well for an hour or two), occasional morning irritability (along with the grogginess. I like Seroquel XR signficantly better than Seroquel instant release because it has been weight neutral for me. I will say that Seroquel is a great sleep medication and did knock out my last mixed episode. I take it all at night so once the morning grogginess wears off (at 9 or 10 am) I am fine. F 41 6 months
150/100 mg 1X day
11/16/2012
 5  schizphrenia Drowsy, a lot LESS sedation than the immediate release. NO akathisia, NO weight gain. This is a blockbuster med! This is a whole different drug compared to the original. Clears my head straight away after taking it. Amazing stuff. 3 years
600 1X day
11/8/2012
 3  Bipolar Depression Severe drowsiness, weight gain, "hangover" effect in the mornings. I was prescribed this in 2010 for bipolar depression, and honestly it worked very well for that. My psych told me the XR version wouldn't give me the morning hangover; HA wrong! At times it could take me upto an hour to fully wake up and a few times I was late to work because of this. But DID really help with the depression I was going thru at the time. True it knocked me out bigtime, but that was trivial compared to the positive effects I saw. Decided to get off it because of the drowsiness, but now thinking of talking to my new psych about re-starting it. M 29 16 months
300 1X day
11/8/2012
 1  Depression My 14 year old daughter suffers from depression and only got partial relief from taking 60 mg of fluoxetine. She also has difficulty sleeping at night. Her psychiatrist wanted her to try Seroquel XR for weeks but I was leery because this medication is only FDA approved for schizophrenia and bipolar disorder. Also, the side effects that this medication carries can be heavy. Unfortunately after weeks of convincing, we agreed to try 50 mg of Seroquel XR before bed. The next day my daughter could hardly get out of bed. She could not think straight, was dizzy, and felt more depressed than ever. She also kept having chills though she had no sign of any illness such as fever, swollen glands, etc.. While she did sleep all night with the 50 mg dose, she was in terrible shape the entire next day. I would never give this to her again. F 14 1 days
50 MG
10/12/2012
 3  Bipolar I Disorder Probably gained 50 pounds on this med. I also got a very rare side effect called Pisa Syndrome(google it) From the waist up I lean to the left. Not that noticeable but you can see it. It is caused exclusively by long term exposure to antipsychotics. I had to have an MRI and had to educate my psychiatrist on Pisa Syndrome, he had never heard of it. Doctors are writing scripts for this pharmaceutical superstar for everything under the sun. I've read that some doctors will call it a sleeping pill at low doses. This is not a sleeping pill, it's an AAP and you should know that. I have three problems with it, you can double your body weight in a year, not everyone but it happens. You can get Diabetes regardless of weight gain. You can get a weird side effects like the one I listed. I am now on disability and I'm dropping Seroquel because it would cost $550 for 30 300mg tablets. The price point on this drug should be illegal and Big Pharma execs in jail. This stuff could be the first thing your doctor wants to treat your depression, sleep disorder, PTSD, broken finger with. They will write it for anything. On the positive side, it did work for me somewhat. But ask yourself, do you want your review in a year to look like mine? M 59 4 years
300MG 1X day
9/28/2012
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 5  Bipolar Just sleepiness and weight gain about 5-10 pounds I cannot seem to take off with diet and exercise. A very small price to pay for my sanity. I was suffering before I started taking this drug. Almost every day I can think clearly, I'm mentally and emotionally stable and am no longer plagued by my symptoms. I cannot express how grateful I am for this medicine. M 25 2 years
400 1X day
9/2/2012
 3  schizophrenia wight gain - sleepy in the morning. seroquel is good to preventing relapses. M 22 10 weeks
1000 mg 1X day
8/30/2012
 3  schizoaffective disorder Works great for mood and psychosis. however i have no volition and no creativity. some weight gain and extreme fatigue. dry mouth and stuffy nose. i also take wellbutrin and abilify. i want to try something instead of seroquel. M 22 1 years
350 mg
8/25/2012
 4  major depression Weight gain. Drowsiness. I've started taking 50 mg 2 hours after I wake up in the morning, then I take another 50 mg tablet every 3 hours afterward. I've noticed I don't feel as spaced out and groggy in the morning and during the day with this method. At around 6pm this evening I will try cutting one 50 mg tablet in half to see if I go to sleep earlier and wake up easier with less groginess. I use to take 150 mg at around 3pm. But, I would still feel groggy in morning and the med would wear off before it's time to take it again. This new method is working for me better with XR. I don't feel as sleepy and spacey during the day. So, here's what I'm doing: 50mg at 8:30a.m., 50mg at 11:30am, 50mg at 2:30pm, then cut 50 mg in half at 6:00pm and go to bed soon after. Wake up earlier and easier. I hope. F 46 3 years
200 mg 1X day
7/16/2012
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 4  Bipolar II / BPD Severe weight gain (over 100 lbs) Tiredness Elevated cholesterol Slowed reflexes F 21 1.5 years
250 mg 1X day
7/2/2012
 4  Bipolar and Schizotypal Gained 42 pounds, feel apathetic, reduced creativity, sleep about 11 hours, no sex drive and not much of an orgasm, don't think as much about things. Has stabilised my moods for the most part. I used to be an ulta rapid cycler. Doesn't do much for my anxiety (I also take quetiapine IR 25mgx4 a day for that, but it doesn't do much except improve sleep). Practically eliminated by paranoia, but not all abnormal thoughts. Blocks out my soul, which I do not like. M 38 4 years
600mg 1X day
6/15/2012
 5  severe anxiety weight gain, memory loss, tiredness yes, side effects suck, but if not this medicine i would be in the nuthouse right now in the long term unit or dead from taking my life. This is the only medicine that helps my anxiety, my psychiatrist said this is the best antipsychotic medication. They say you need 125 mg for anxiety or something, personally i think everyone is different, I started with 300 mg when i was clinically suicidal, after two years of intensive recovery it was too much for me so i went down to 50 mg. My doctor disagrees, but I don't give a damn, they just say what they are told to do, and afraid to say any different cause the dont want to be sued. F 27 3 years
50 mg 1X day
6/13/2012
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 5  Migraine Weight gain of 20 lbs in less than 6 months. No other side effects. Worked great for daily migraine attacks. F 29 1 days
400mg
4/15/2012
 2  Bipolar Vivid Nightmares, Frequent Urination, Extremely Tired (Can Sleep 12 Hours Straight) F 23 2 years
150 MG 1X day
3/19/2012
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 4  schizophrenia/ptsd/agoraphobia dry mouth, occasional restless leg syndrome, loss of appetite, drowsiness, constipation, insomnia if a dose is missed. started on 150MG 1xday helped with depression, after three months was interested in hobbies and things again. dose not high enough to aid anxiety/phobias/paranoia/schizo symptoms. am gradually upping dose until correct one is reached, under docs watchful eye and regular blood work/review of any side effects. so far i have lost 7 lbs and am more active. 1-2 nights a week i get mild restless leg syndrome. i drink more water thanks to the dry mouth. i have to say so far my experience with this drug is wonderful. i love it. i finally have found great hope to have many schizo symptoms helped. F 52 4 months
300MG 1X day
2/10/2012
 4  ptsd, bipolar, soc. anxiety, depres I had immediate anxiety relief and my thoughts slowed down to one at a time and I could actually think. The downside of that was laziness, I could not get motivated. I have to choose between uncomfortably numb or my hectic mind. Also, at bedtime I would start JOLTING and had to jerk my limbs around excessively for well over an hour. So not only was I very sleepy because of the dose, I was jerking around like a crazy person. I still feel this sensation in my arms. Also, my muscles got very weak, to the point of barely being able to bear my own body weight. Sad too, cause it helped my mind... F 25 6 months
300 mg
2/5/2012
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