SEROQUEL XR Reviews (QUETIAPINE FUMARATE)

Average Rating: 3.1 (142 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL XR  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). It is also used with other medications to treat depression. Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2007-05-17 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUEL XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  bi polar type 2 Drunk and sluring weight gain, exhausted, no joy, numb I am currently weaning my self off I really prefer the mania and I am still fully function during an 'episode' I think the Dr should b more concerned about bringing u out of the depression than getting u off the high! F 43 3 months
350
10/16/2014
 5  schizophrenia This is so different to the original seroquel. Seroquel XR has changed my life around. This is the only antipsychotic that doesn't cause restlessness for me. I've been on it for 4 years. I highly recommend it. M 27 4 years
800
8/5/2014
 3  Bipolar II Disorder/Panic Disorder Initially while in the hospital I was put on Seroquel XR at 150mgs daily, Oh wow,it was like being hit with an elephant tranquilizer. I walked around in a dazed like state for the duration of the hospital stay. I was technically feeling less depressed & anxious however it was because I was anesthetized basically. Once I arrived home I stopped the 150mgs & dropped down to 50mgs for a total of one day (I don't recommend it to anyone) The withdrawal on 1st Day was horrible do I titrated up to 100mgs per day & have been on this dose for the last 5 days & am much better. However my concern is, during the first couple of days taking the 100mgs, each day felt as though a heavy overwhelming weight was beginning to lift off me & I was mentally more clear, and definitely responding better & better with each day. It was indescribable,the new sense of hope & possibility that I was beginning to have...I wanted to eat,I wanted to get up out of bed in the morning, I wanted to live life once again after such a long time. But then yesterday & today the fog of depression has slowly moved back in, I've become irritable & impatient. I don't quite understand what could be happening? Is fluctuations like this in the beginning to be expected? IF so, when can I anticipate finally having balance? Could I have already acclimated to the dosing & am requiring a higher dose? Or is this normal? M 36 7 days
100 mgs
7/30/2014
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 5  Bipolar This is a wonder drug for me. No more racing thoughts and my psychosis is quite. Believe it or not, I have to take it when I first wake in the mornings. The antihistamine affect makes me restless in stead of sleepy. F 53 2 years
600
7/7/2014
 4  Anxiety, Sleeping problems, etc The first time I took this felt like a shot of the world's most powerful elephant tranquilizer, it was beyond anything ever imaginable..Good thing I was staying somewhere with doctors nearby, probably would have given myself a heart attack. But the next night was better, wasn't long after that I could take it and fall asleep an hour later. M 32 3 weeks
100 1X day
3/30/2014
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 4  I have bipolar Non xr was good for this time. But I was unable to cope when my passed away on this dose cause the alcohol amount made it obsolete.so if you c signs of unwellness need to c psychiatrist. F 37 2 years
30 mg
3/29/2014
 5  Manic/Anxiety & Depression/Insomnia Dry mouth. Groggy in the morning for a few days, but that went away. Slight loss of appetite. Slightly agitated in the early evening before next dose, but that went away, too. Good side effects: Killed the manic episode and let me go to sleep (finally!). No more racing thoughts 24/7. I can actually meditate now. I'm able to get up and go to work! I haven't missed a day of work since I started this med, which is very unusual for me. I was terrified to try this medicine after reading all of the negative reviews. Unfortunately, the very people who are prescribed this drug are the ones most likely to be extra-sensitive to negative side effects. I'm certainly in that group. But I'm glad I gave it a shot. I also take Lexapro 10mg. The extended-release version of seroquel doesn't PUT me to sleep; it LETS me go to sleep. Big difference. The main issue that bothers me (and this is kind of petty) is that I have to take it (1) one hour before I eat; (2) three to four hours before I want to go to bed; and (3) twelve hours before I want to wake up. Whew! That's a pain in the ass! So, my schedule is this: take pill at 6:30 pm, eat dinner at 7:30 pm, get up for work at 6:30 am. I hate following this strict schedule, but you have to choose your battles and the strict schedule is better than being bat-shit crazy. I haven't gained any weight, but I'm a mostly-vegan vegetarian that only eats healthy food. I don't eat any junk at all...no refined sugar/bread/pasta/fast food/soda blah blah blah you get the picture. I hope the dry mouth issue improves...the other night I drank 32 ounces of water THROUGHOUT THE NIGHT as I was trying to sleep...which of course led to having to get up to pee-pee! Not cool! F 47 3 weeks
300 MG 1X day
2/28/2014
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 4  Mania No side effects except it makes it hard to get out of bed in the morning if I take my dose too late the evening before. My doctor said take the dose 12 hours before you wake up. i find that taking it 14 hours before my wake up hours curbs the sedating side effect. (I take it at 6 p.m. and wake at 8 a.m.) Seroquel XR was prescribed as an alternative to Zyprexa, because Zyprexa was causing me to eat everything in sight and gain an unseemly and dangerous amount of weight. I notice a slight uptick in appetite with Seroquel XR, but nothing compared to Zyprexa. the appetite increase is so much more manageable. It does not make me feel quite as good (rosy, optimistic) as Zyprexa but it does the trick of quelling my mania and keeping me in a pretty good headspace. I take this with 600 mgs Lithium XR. Combine this med with conversation from wise friends or counselors. I learned I still need to correct thinking errors to feel much better. I learned to quit personalizing others' mistreatment of me, for instance. F 36 21 days
150 1X day
2/6/2014
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 1  Bipolar Depression and Insomnia Side effects experienced with SEROQUEL: Worst drug ever. Takes (3-5) hours to put you to sleep. Than you have horrible nightmares and remember all your bad dreams the following morning. Does not improve depression at all, makes it worse! The XR version will make you completely incapacitated the following morning to the point where you can't even move your body; literally. Completely halts the effect of stimulants like Vyvanse used for major depression and enabling you to get out of bed in the morning. Worst sleep aid on the market and no patient assistance programs exist. Also terribly expensive. Consider another antipsychotic such as Abilify or Saphris, you'll be glad you did. Plus Abilify and Saphris and Vyvanse will give them to you for free if your income is low enough; generally under ($25,000 annually). M 31 2 months
200 MG
2/4/2014
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 3  Bipolar disorder (yay!!) Frequent nosebleeds, tiredness, sleepiness in the morning and before night (since I took it at 4PM daily), slower than normal thinking. Seroquel makes me calmer, helps me sleep, and for some unknown reason cures my eczema. It did not help me with anxiety/paranoia though. It considerably increased my appetite. I cannot stop eating!:) M 28 7 days
100 1X day
11/13/2013
 1  insomnia Cannot concetrate during day and other problems. After 4-5 years of use I now has breathing problems that are probably related to dysautonomia and brain damage (brainstem). One has to discontinue these medications before 4 years or something or one will die to medication side-effects. Seroquel IR 400mg/night didn't cause problems. Switching to the prolong (XR) caused concetration problems and other issues which disappeared when I switched medication back to Seroquel IR 400mg/night. M 32
400 1X day
6/29/2013
 3  bipilar M 37 1 weeks
800mg
6/18/2013
 1  Psychotic Depression Legs hurt, not helping my psychotic symptoms, crippling depression This has been the worst point of my life in what has been the worst year of my life. I was on Olanzapine (10mg) which stopped working effectively, and I switched to Seroquel slow release tablets three days ago. I am ashen. This is destroying me, I've never felt so awful before in my entire life. I'm not even sure I'm going to make it. This medication may work for you, but for me it has turned my life into a living hell. Think VERY carefully before trying it when your current medication is working (even though mine wasn't). M 24 3 days
50 MG 1X day
6/17/2013
 4  Bipolar II Initially very dry mouth but this went away. Weight gain. This drug was a miracle for me. It balanced out my mood brilliantly and helped me sleep. Unfortunately I put on 20kg in the time I took this drug so decided to look for something more weight friendly. I was ALWAYS hungry and craving carb-loaded or sugary foods. F 28 9 months
400 1X day
6/1/2013
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 5  schizo-effective, bipolar disorder Was switched from seroquel 300mg after ten yrs of use to seroquel xr. I have to say these 4 months have been great. This medication has been a true help.My thoughts are clearer and I am happy to be alive. I am working and living a healthy life. This medicine is a God send. F 32 4 months
300mg
5/5/2013
 1  Dx with Biopolar at the time Worst medicine I've ever been on! It caused me to loose my job. I had hallucinations from it. I was agitated, confused, and in a complete disarray from it. I do not recommend this to anyone. F 25 2 weeks
1X day
3/30/2013
 5  PTDS Very few at all - I take it a few hours before bed so if anything it helps me sleep. I have noticed some minor weight increase (1lb) but time will tell if this is a trend. Overall, I feel great. I started taking this medication for PTSD and it worked like a miracle. It calmed me down, it stopped my racing thoughts, it stopped my obsessivness, and it helped me sleep. For me it was truly a miracle medication. I worry about possible weight gain but I will just exercise more. M 37 1 months
200mg 1X day
3/12/2013
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 4  Schizophrenia This stops psychotic symptoms but u have to get the dose above 600mg. Feel sedated most of the day but it IS worth it M 24 3 years
600mg
2/19/2013
 1  bi-polar disorder excessive sleep, slowed speech, troubles making sentences, forgetting words, short-term memory loss, emotionless, fatigue, weight gain I stopped taking Seroquel XR almost 2 years ago. I weaned myself off it over a weeks period and had the most horrible withdrawals following the last days dosage that lasted another week. I couldn't sleep, had difficulties breathing, night sweats, vomiting, extreme nausea, headache, etc. I wish I'd never taken this medicine. I've never regained my once strong short-term memory. I feel I've never been as sharp as I once was. Life on Seroquel XR is like watching a television that has been muted. It's like being a zombie. I tried to explain to my psychiatrist the difficulties I was having and he didn't believe me! He also didn't believe me about the withdrawal symptoms. I say, please use this drug only as a last resort. F 28 2 years
800 1X day
2/17/2013
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 5  depression and Anxiety So far not much. Maybe a headache every so often. Great drug. Took away my depression in 4 days and is reducing the anxiety so far. M 40 13 days
750 mg 1X day
1/31/2013
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