Average Rating: 3.1 (15 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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 1  hrt after menopause Liver enzymes elevated My liver enzymes were elevated after I used Divigel for a few months. MDs didn't see that it was the hrt causing the elevations! Family dr. thought it was vitamins or a virus causing it, but I'm convinced it is the hrt that did it, due to process of elimination. Am now concerned since ultrasound came back indicating scarring of liver, Be careful. I thought I couldn't live without hrt till I realized the liver damage it has done. F 65 1 years
1X D
 1  Vaginal dryness Weight gain Overall it makes me feel energetic and alert, but I gain 7 pounds in a month. So I stop taking F 64 30 days
0.01 1X D
 3  Total hysterectomy Swollen legs. I am afraid if I continue with this medicine I will get a thrombosis. Any advise? Please? F 50 3 weeks
75mg 1X D
 4  Hot flashes and insomnia I'm having fast heartbeat at times . My hot flashes starts when I'm stressed at work . Helps me with my sleep but so many problem with my stomach , taking omeprazole for heartburn now and gassy . I get anxious and it comes and goes with no reason at all . I want to stop because of all the side effects but I'm scared . F 51 2 years
0.75 mg 1X D
 1  Mood and not sleeping Migraine Nausea Back pain Stomach cramps The only good thing from this is it did help me fall asleep. But the negatives are way too great, the nausea first thing in the morning wipes you out and when a migraine hits it's awful spent most of the day in bed today(on my day off) so have made the decision to not use anymore do not feel it is worth it as my daily life is impacted 49 90 days
.1 1X D
 5  hot flashes none 99% of hot flashes gone, headache gone, hair loss improving, sleeping soooooo much better, mood better. I'm feeling fairly Zen most of the time. Period did return due to progesterone, but who cares. I am back to my old self! F 51 2 years
1mg 1X D
 3  Menopause sleep problems No one else has mentioned this, but I think this and Combipatch, which I used before, have both been causing sinus issues- congestion, coughing. Unrelenting cough. I checked side effects, and nasopharygitis and upper respiratory tract infection are listed. I do have allergies, but these hormonal meds have been making cough and sinus congestion/drainage much worse, I think. I am stopping Divigel, hope my appetite lessens and brain fog go away. Didn't help my sleep, but my skin looked younger and osteopenia was improving. F 64 1 months
0.25 gm 1X D
 2  Surgically Induced Menopause Headaches I've been using divigel since my total hysterectomy in November. Even with the highest dose, I continue to have severe hot flashes, fatigue, muscle and joint pain, anxiety and depression, and a low libido. My GYN has suggested that I may not absorb drugs well topically, and has started me on an oral estrogen/testosterone combination medication. I plan to start that tomorrow. Divigel just wasn't for me. F 41 4 months
 4  Menopause Celibate low sex drive hot sweats sleep Anxiety... eased all of it At least now Iím interested again , mind clearer less brain fog I F 49 90 days
 5  Severe hot flashes and night sweats None so far It took 2 weeks to start to really notice my hot flashes and night sweats disappearing. I feel so much better. Not a pool of sweat every 30 minites anymore. Improved my quality of life in that I feel normal again. F 51 20 days
.05mg gel
 4  Hotflashes Insomnia. Cant get to sleep until like 4 or 5 am. Im miserable. Hotflashes gone F 52 4 weeks
 3  Hot flashes, vagina &bladder pain When I use the whole lowest dose, I felt extreme nausea, terrible abdominal cramps and depression . My vagina is red and raw and burns. Iíve tried Estrace and Bi EST. Now tolerating 2 drops of 1mg at night but my vagina burns all day and gets worse in evening requiring ice packs for relief. I am using it because without it I have excruciating bladder and vagina pain like UTI. VERY FRUSTRATING. Very powerful. Iíve been in bladder vagina pain for 6 months. Been to urgent care 3 times, ER visit, Urogynecologist vist, gynecologist visit, urologist visit, integrative physician visit. Doctors just donít seem to be able to help me. Anyone else found an answer to Menopause hell. I need someone near Chicago who can help me. This is ruining my life. F 58 4 weeks
1/2 1mg 1X D
 2  Low Estrogen Level in Perimenopause Weight Gain, Breasts Swollen & Tender, Heavier Periods I had some symptoms of low estrogen which were confirmed by a blood test. Helped me sleep better (used with bioidentical progesterone for 14 days out of the month) but it caused weight gain (even though I exercised and ate clean). My breasts always felt swollen and tender and my bras didn't fit. I actually stopped taking it cold turkey and my breasts returned to a more normal state and I am fitting into pants I couldn't before. The problem now is I am experiencing acne breakouts since going off it. Be very careful and do your research before going on these hormones whether they are bioidentical or not. They are powerful! F 45 2 years
.50mg 1X D
 5  Low Estrogen Level; Perimenopause None I am perimenopausal. Had blood levels tested for all hormones and estrogen level was very low. Adding a small dosage of Divigel really helps. Very easy to apply on a daily basis and the packet is convenient to travel with. Gel is absorbed immediately. I take in conjunction with other bioidentical hormones and have my hormone levels monitored on a yearly basis. F 44 1 years
.25mg 1X D
 4  Terrible migraines I played around with different strengths and settled for 1mg and the dose is split in two doe the day am and pm. I am very sensitive to estrogen and this bring my level up gradually. I had intense migraines at 51, which came out of the blue and this all has eliminat them including hot flashes. The gel dries quickly and you can titration up or down if you exercise, etc. I tried to lower the dose since I thought it was giving me gallbladder issue and my vagina is raw and inflamed. I have titrated back up, so hopefully that will work. NOTE exercise a lot and not sure if I am metabolizing more o the gel, so I may need something local (estrace, vagidem) in addition to the Divigel. Anyone have experience with local bio identical estrogen? I like the portability and ease of the Gel. F 55 4 years
1mg 1X D

DIVIGEL  (ESTRADIOL):  This medication is a female hormone (estrogen). It is absorbed through the skin and enters into the bloodstream. It is used by women to help reduce a certain symptom of menopause (hot flashes). Symptoms of menopause are caused by the body making less estrogen. If you are using estrogens to treat only vaginal symptoms of menopause (such as vaginal dryness/burning/itching), products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.   (Sources: U.S. Centers for Medicare Services, FDA)