TEKTURNA Reviews (ALISKIREN HEMIFUMARATE)

Average Rating: 2.4 (47 Ratings)

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 ANTIHYPERTENSIVES

 Type: Rx Drug

  

TEKTURNA  (ALISKIREN HEMIFUMARATE):  This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Aliskiren works by relaxing blood vessels so blood can flow more easily. It belongs to a class of drugs known as direct renin inhibitors. This drug is not recommended for use in children younger than 6 years or who weigh less than 44 pounds (20 kilograms) due to an increased risk of side effects.   FDA Approval Date: 2007-03-05 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on TEKTURNA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TEKTURNACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  blood pressure This has got to be one of the worst medicines that I have ever encountered! It made my joints ache, I felt like I had been posioned-my stomache felt like a was going to throw up all of the time, it put so much pressure on top of my head that I thought it would expode, no sleep at all, thank god my doctor changed my prescription. It did keep my blood pressure in check, but created so many other problems, never take that again! F 66 35 days
150mg 1X day
7/6/2011
Email
 1  HBP At first, I did not suspect this med. I thought I'd gotten an upper resp infection. My cough started slowly, like when you have bronchitis and quickly worsened. I was so busy at work, I was trying to push through it. Went to doc to see about what I thought was bronchitis, and found that my blood pressure, which had been somewhat high (150/80) was now 290/212. I was admitted to the hospital, for what was expected to be an overnight stay, turned into 11 days. Tekturna caused immediate CHF and a myriad of other issues. My blood pressure has not been controlled since, but not as severe as when on this med. Because of this incident, I am now uninsurable, lost my health insurance and have more problems than ever - not to mention huge medical bills I'm still paying off. I would NEVER take this med, or any other in this class again. Agreed - the clinical studies on this were extremely skewed. I am so sorry I ever tried this med. For 25 years Zestoretic did a very reasonable job with many fewer side effects. F 58 15 days
150 mg 1X day
6/26/2011
Email
 4  high blood pressure bp rose very high initially at night, but I felt energetic in the day. Doc changed to HCT formula. It still didn't work to lower bp, but I loved how I felt. Diovan added..mostly works now. I take 150 in morning and again in early afternoon (not at night, cant sleep). I must diet (Atkins) or I would gain weight rapidly. All worth it to me to feel good and not so tired. F 69 5 months
150 mg 2X day
4/29/2011
Email
 1  High Blood Pressure Moderate difficulty breathing; dizziness & light headed; rise in BP & pulse rate over 10 days from 122/70 to 167/82; dry cough; I took for 10 days and my BP went up a little each day and developed the side effects mentioned to the left. Called Doctor and he told me to stop taking tekturna, and go back on Verapamil ( which caused MAJOR palpitations - so I'll be med free until he figures out what to give me next). It seems Tekturna doesn't lower BP for a lot of people from what I read in this site. The Novartis (maker) website barely touches on this side effect in their clinical trials, saying only that ...2.2% of patients were removed from tekturna for "uncontrolled hypertension. 2.2% of 6,450 patients in the trial = 142 people. What good is a BP med if it RAISES your BP? Want to see the shocking truth about how patients are chosen for "clinical trials?" GOOGLE Clinical Trial, and read the WikiPedia article. Women, children, the elderly, and those with common medical conditions are frequently excluded from trials. That is to prevent those people from having adverse effects to skew the results of the drugs during trials so the FDA will approve them. Yet the drug will be prescribed to those same women, children, the elderly, etc at some point, and they will experience bad reactions to the drugs, reactions that would have been discovered in trials. All so the Pharmaceutical Industry cam earn Billions of $$ a year in obscene profits. M 55 10 days
150 mg 1X day
12/3/2010
 1  HBP By the 5th day began having severe and constant arrythmias, to the point that ER trip was needed. Had been taking Cozaar (Losartan) also, so perhaps the two combined contributed. (?) No heart problems were discovered, so it appeared that the only variable was the initiation of Tekturna. Wonder if anyone has had this problem, because journal evidence does not list arrythmias as a possible side-effect. Wonder if anyone has had this problem, because journal evidence does not list arrythmias as a possible side-effect. F 63 5 days
150 mg 1X day
9/1/2010
 1  High BP gingival pain , headache and stomach cramps. Didn't lower BP at all. M 41 2 weeks
150mg 1X day
8/24/2010
 4  high blood pressure Headache, neck pain, muscle pain, diarhea, throat problems After taking other BP drugs for years with terrible side effects, Tekturna helped get BP down to average 135/70 and holding. It was reduced to one 150 mg tablet per day with success. I hope to get it reduced to 75 mg soon. M 79 22 months
150 mg 2X day
7/25/2010
 2  Hypertnesion Weight gain, depression and doesn't lower bp enough. Stays around 145/89. F 51 3 months
300 mg 1X day
7/20/2010
 1  hypertension bad stomach cramps, diarrhea, difficulty swallowing, rash on face would not recommend this drug to anyone M 59 60 days
150 1X day
4/27/2010
 2  hypertension little diarrhea, and head throbbing blood pressure actually went up from 150/90 to 180/100 M 47 30 days
300 mg 1X day
2/13/2010
 1  High Blood Pressure After one week, experienced no change in bp rate. Difficulty breathing, rash on neck, hard to swallow, tired and 5 pound weight gain. Since day one, experienced severe headaches - all day. F 49 6 days
2/3/2010
 5  High Blood Pressure Have had high BP for about a year. Almost every BP med I tried has had bad side effects EXCEPT Tekturna. I am taking 150 mg. Tekturna twice a day plus 100 mg Metoprolol twice a day. Began a year ago with BP at 212(!). Now in the 130's. New drug... your insurance may not cover any/all of the cost. Great stuff...give it a whirl if you've had problems with other BP meds. M 62 2 months
1/16/2010
 4  High bp Tried Diovan, Benicar (cough with those) but Tekturna has least side effects. Worst side effect for me is weight gain. 10lbs in 5 months @ 300mg. On about 500 calories a day and cannot drop weight. Tinitus. Achy muscles(neck and lower back)every so often. It has affected my personality, not as much enthusiasm and drive which is very dissappointing. It has controlled my bp so far. F 64 5 months
12/26/2009
 4  HBP I have tried every BP medicine and could not tolerate any of them. Tekturna (150mg) works for me, but I do have some side effects that are very bothersome. I have serious insomnia, and my heart beats rapidly, as high as 95-109 beats per minute. My Dr put me on Inderal to lower my pulse, but the insomnia persists. Also started getting short of breath and cut my pill in half. It remedied this. My Dr explained that this medicine builds up in your system, and if you quit taking Tekturna, it would still lower blood pressure for 2 weeks. F 56 8 months
10/1/2009
 5  hypertension I tried eleven (11) other medications before trying Tekturna and was either allergic or had horrible adverse reactions, and my blood pressure would not get lower. I've been taking 300 mg of Tekturna for 8 months now, and my blood pressure is normal. Also, I don't have any side effects! Thank goodness for Tekturna. It saved my life. F 55 8 months
8/17/2009
 2  High BP none Doesn't help whatsoever. asking for something else. M 68 4 weeks
5/26/2009
 1  For High Blood Pressure Increased my High Blood Pressure even further Dizzy, Pain in the legs and abdomen, in general unwell feeling Would not recommend it. F 67 4 weeks
4/26/2009
 3  High BP Only on Tekturna for 2 weeks and so far it's worked great, with no side effects. Literature says diarrhea is the most common but I've had none. Also read that it works much better with Diovan combined. So far it's working well by itself 135/70 but since I was on Diolvan alone before(which did 'not' keep my BP stable it was erratic but no side effects) I'll keep that in mind and if the BP does shoot back up I'll add the Diovan back with the Tekturna. I liked the way it worked directly on the Renin, differently than the ARBs or ACE inhibitors or esp. the Beta blockers. Fingers crossed. F 55 2 weeks
4/10/2009
 3  High Blood Pressure No side effects noticed, except for maybe making my bp go higher. Worked great (150mg) .. for about 2 months. Doctor said if bp starts to creep up, then to double the dose. I moved to 300mg for a few days, which made me feel even worse, and my bp went up even higher. I read that the renin rebound is higher with these types of drugs when compared with the ACEs and ARBs. Was then given 5mg lisinopril (dad's been on this one @20mg with success for 10+ years) to add to the 150mg tekturna, which worked, but too good. I started consistently getting 100/60 readings with heart rate high 70's in the evening, and my body just didn't feel right during those times. After a month and a half of that, I went to tekturna 150mg and lisinopril 2.5mg. In less than a week, bp was up and I felt like crap. Switched back to 150mg/5mg for a little over a week, which brought things down again, but like before. I then switched to tekturna 75mg and lisinopril 5mg, which brought me energetically and bp I do yoga once a week and practice a martial art twice a week. If I open up and share that I battle high blood pressure, people are shocked. I will say, during the times when taking this drug and when the bp has been under control, my sexual responsiveness was improved. With that said, to all that are looking for the right bp drug for them, I say this one's worth a shot. M 33 6 months
2/11/2009
 5  High BP None. I have been taking Tekturna for well over a year. It has lowered my blood pressure and I have experienced no side effects. M 50 1.5 years
1/25/2009

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