AMITIZA Reviews (LUBIPROSTONE)

Average Rating: 3.0 (44 Ratings)

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 LAXATIVES

 Type: Rx Drug

  

AMITIZA  (LUBIPROSTONE):  This medication is used to treat certain types of constipation (chronic idiopathic constipation, irritable bowel syndrome with constipation). Chronic idiopathic constipation has an unknown cause and is not due to diet, other diseases, or drugs. Lubiprostone is also used to treat constipation caused by narcotic (opiate-type) medications in people with ongoing pain due to medical conditions other than cancer. This medication may improve symptoms such as bloating and abdominal discomfort, improve stool texture, lessen the need to strain, and decrease the feeling of not completely relieving oneself. Lubiprostone belongs to a class of drugs known as chloride channel activators. It works by increasing the amount of fluid within your intestines, making the passage of stool easier.   FDA Approval Date: 2006-01-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction highest to lowest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR AMITIZACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  medication-related constipation Chest tightness, mental fogginess, fatigue In 45 days I've had three spontaneous BMs. I continue to experiment with additional measures, based on MD recommendations. Currently I also take 2 to 4 magnesium tablets/day; 3 stool softeners; 5 soluble fiber capsules with lots of water; 2 sennas (at night); and use 1 or 2 suppositories. I've had only 1 spontaneous BM in 45 days that was "enough," so I used a suppository even after the other 2, producing an equal amount on the 2nd try. I'm highly motivated, as the medication that produces constipation gave me a large+small bowel impaction this summer, which turned into an obstruction, and I had to take Supraprep via nasogastric tube in the ER to clear it. I'm disappointed that Amitiza isn't very effective, and worried about my quality of life if I keep being unable to concentrate very well. BTW, the web page e-mail address is required ONLY if you want to be able to edit comment or be contacted by others, but the Review button won't work unless an e-mail is entered! F 69 45 days
24 mcg 2X day
10/17/2015
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 3  Gluten intolerant,chronic constip. occasional shortness of breath, achy joints, bloated feeling, diarrhea, occasional headache When I first started taking amitiza it would make me bloated and full feeling. Sometimes I would have a bowel movement, sometimes not. If I did not it was a pretty uncomfortable feeling most of the day. I did have the shortness of breath a few times. I was taking it twice a day as recommended. It was brutal in the beginning. I was desperate though, from the discomfort of the constipation. I started reading about how the medicine worked and started my own trial and error of the best way to take a dose. I stopped the twice a day for one because it made me feel terrible all day and evening. Eventually I stopped taking it with food early in the morning, and would take it with a cup of coffee. In 1-4 hours I would have a bowel movement. It was usually just diarrhea, but it relieved my constipation, and I generally felt better. I have been taking it off and on for several years now, and I know this; if I take it on an empty stomach, it works better. I drink a bottle of water and generally a cup or two of coffee. It's difficult to have to wait around in the morning for a bowel movement, especially when it comes on the way this medicine brings it on. What I have begun to do now is set my alarm and take the medicine about 2 hours before I get up in the morning. It seems to work. I get up, and within and hour I'm going to the restroom generally. I try to eat pretty quickly, and it usually makes my stomach feel achy for a little while after, but it's much better than feeling aweful for M 38 4 years
24mcg 1X day
1/15/2015
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 3  Severe constipation F 53 1 days
24
12/27/2013
 3  IBS-C Initially worked for 5 days, then constipated again. I will take it intermittently because when taking it regularly it doesn't work anymore after the first week and I'm constipated again, why continue to take the poison. F 32 3 weeks
8 mcg 1X day
6/12/2012
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 3  IBS C None I haven't noticed any improvement in symptoms yet (that's why I only gave this a 3), but I wanted to report that I do not have any side effects either. I was advised by my Dr to take this for 4-6 weeks before "giving up" (she said it could take that long before seeing full effectiveness) & if there was no improvement, we'd go from there/explore other options. F 38 5 days
24 mcg 2X day
11/1/2011
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 3   Worked sooooo well for my constipation! So effective I only have to take it everyother day! The only side effect I have is nausea but I have a zofran Rx for that! F 25
9/13/2009
 3  chronic idiopathic constipation extreme watery diarrhea It works great, you definently will not be constipated however you may end up in the bathroom 11 times a day with solid water diarrhea F 22 3 months
2/28/2008
 2   None Worked well at the beginning, after 3 or 4 days I was back to suppositories. M 83
2X day
6/2/2020
 2  Bowel resection / non working colon I have had bloating, extreme dizziness to where it's affecting my everyday life! Have had to go to the ER already was taking with Relistor shot as well every other day. I have stopped everything except the Amitiza, Miralax, colace, senna laxative, now I'm on meclizine but it's not helping! I've been bloated having heartbeat in my head ! This is very bothersome the Dr said its meds or a bag ! Any opinions or input ? F 40 3 weeks
24 mg
6/19/2016
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 2  constipation Helped with her idiopathic constipation. . But caused horrible chest pain and tightness. Shortness of breath. F 10 3 months
30 mg
4/5/2015
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 2  pain mgt patient narcotics=constipation was so hopeful it would work. second day I started to get dull headaches, nothing I couldnt deal with. 5th day still havent gone and It was 13 days total. 6th day dizziness set in just slight. 12day dizziness consuming my life. Stopped immediately. Never had bowel movement w Amitiza without using laxative The copay of new drug would have bn worth it if the drug worked. so dissapointed. F 56 2 weeks
24 mg
3/2/2015
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 2  Chronic constipation I developed an infrequent dry cough on Amitiza and it hadn't started working afte 2 weeks so I stopped using it. I had been constipated for about 10 years, since moving to Florida. One day I saw rust stains in my toilet after returning from vacation and realized there was a lot of iron in my water. I know iron can be constipating, so I added a type of salt to my water-softener that takes the rust out. Since then I am no longer constipated. Perhaps doctors should ask about iron in water before prescribing Amitiza! F 61 2 weeks
24 mcg 1X day
7/29/2014
 2  Chronic constipation Nine in low dose. Higher dose, more bloating, chest and throat tightness, wires dry mouth, belching more This has done absolutely nothing to help my constipation. If I take Miralax, I gave a small BM in the morning. Doctor says to give it a chance to work. It's been a month and almost 2 weeks at the higher dose. I feel worse than I did. I want off this drug. F 64 28 days
8 mcg & 24 2X day
3/20/2014
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 2  Constipation Headache, chest tightness, shortness if breath, palpitations. I have been taking this Med awhile now. It relieved my constipation without any problem but I could not handle the side effects. F 34 2 months
24ng
5/27/2013
 2  Celiac complications/constipation Painful, cramping stomach. Nausea. Body aches. Sudden onset of bloating/gas that does not improve with BM. This medication was helpful for the first week or two, but for the past 5 days I've felt like I had a stomach bug. No vomiting, but very nauseous and my stomach is very sore. Also extreme bloating has returned. Not sure if I should keep taking or not. F 27 3 weeks
8 MG 2X day
2/21/2013
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 2  IBS-C I have dealt with constipation all my life but only recently witht the severe bloating, abdominal pain and distinction. The first two weeks, this was a miracle drug. I felt normal for the first time in my life. Having BM daily and eating without bloating. For the past week, effectiveness is gone and I'm back where I started. Doctor wants me to continue. Absolutely devastated. F 26 3 weeks
2x D 24 mg
12/21/2012
 2  chronic constipation No change. The drug simply doesn't work for me. Obviously, lots of people really get enormous relief from this drug. We're all different -- I'm one of the unlucky few the drug doesn't help. What a disappointment. F 65 3 weeks
24 mcg 2X day
10/4/2010
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Patient History
 1  Chronic Idiopathic Constipation I had no side effects. This drug did not work for my constipation. I took 2 a day, gave me diarrhea. Then did 1 a day. Still nothing. Added 2 dosages a day of miralax with it, gave me diarrhea. It gave me 1 BM in 6 days. Very disappointed with this drug. F 57 14 days
24 mcg
6/30/2020
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 1  Chronic Constipation Nausea and dizziness I started slow with one pill before I added the 2nd as I didn't know how it was going to work. Well I just didn't feel well from day one of taking it. I started getting mildly dizzy but only seemed to show up when sitting. I continued as it did help some and hoped side effects would go away or I could handle them. Nope! Dizziness increased. So at about 3 wks I stopped taking it. That was 2 wks ago. The nausea left immediately but I am still having a terrible time with the dizziness. Never was dizzy before this. F 57 3 weeks
8 mcg 1X day
8/30/2016
 1  Chronic Ideopathic Constipation Severe Nausea, Sometimes Leading To Vomiting After Dosage, Acute Cramping, Gas, Severe Spasms In Colon, Aching! Sometimes Takes 1 Hr To Work But Lately 3-4 or Even A Greater Amount Of Time For Results Of Severe Watery Diarrhea, 3-5X Each Day! The Waiting Is Exacerbating And Extremely Painful NOT TO DOWNPLAY The Bloating And Gas Which It Doubly Uncomfortable! Then, The Actual Bowel Purge, Itself Causes Great Dehydration, Exhaustion, Spasms, And Aftermath Pain! This Super Strength Laxative, Is Worse Than A Colonoscopy Prep, As It Works Very Unpredictably, Is Mostly Unreliable And Leaves One Utterly Fed Up! I Find Myself Wondering, Why I Am Putting Myself Through This Torture! The Nausea, Spasms And Pain, Truly Bring me to the point of Needing To Vomit, To Get Some Relief Of The Bowel Pressure, And Nausea Occasionally, I Do, But It Rarely, Brings Great Relief! Same Said For The Bowel Purge! Major Bouts Of Watery Diarrhea! Seldom, Formed Stools! Regimen Seems To Take Up 4-5 Hrs In The Morning Until Noon! Very Dissatisfied! This Is Like Prepping W Poison Or Dynamite! 😷 I Want OFF This Bomb , I HATE IT! 😠 Thanks For Putting Yet Another Drug W Horrible Side Effects, Which Cause The Individual Who Has No Other Alternative, Due To "Chronic Idiopathic Constipation " From " Chronic Inflammatory De-Mylonating PolyNeuropathy-CIDP" WORST DRUG W Side Effects That Is Currently On The Market! Please Develop A Better And More Gentle Pharmaceutical Alternative, My Father Is Seriously Suffering From All Amitiza Side Affects And It Has Only Continued To Raise Havoc For Him Each Day Of His Essential Bowel Purge! Acute Spasms, Pain, Severe Nausea, Vomiting, And Bloating From Distention, There Must Be Another Way! This Drug Appears To Be Counter Intuitive To It's Desired Goal, Thereby Causing Greater Spasms, Acute Pain And Severe Nausea That Often Causes A Worse Bowel Purge, Than An Easier, Less Torturous Manner Of Side Effects, That Ultimately Cause The Individual, To Feel Better, Not Worse From Daily, Unpredictable Use! It Is Difficult As A Spouse And/Or Care Provider To Witness Such Acute Symptoms And Severe Intestinal/ Colonic Pain And Discomfort Of Individual Taking This Harsh Drug! Please Work With The FDA To Explore Less Toxic Options And Less Undesirable Side Effects while Still Achieving This Type Of Drugs Ultimate Goal! Thank You! Concerned Family Member, And Patient Advocate! M 78 2 months
8 MCGS
11/26/2014
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