SYNTHROID Reviews (LEVOTHYROXINE SODIUM)

Average Rating: 2.6 (900 Ratings)

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 THYROID ANTITHYROID

 Type: Rx Drug

  

SYNTHROID  (LEVOTHYROXINE SODIUM):  Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer). This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.   FDA Approval Date: 2002-07-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SYNTHROID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SYNTHROIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  TT (cancer) Intially only side effect was sweating. Now that dosage has been corrected, everything is fine. I have lost 35 lbs. through correct eating and exercising during the past 7 months. This drug will not make you gain weight. If you eat too much or don't exercise you will gain. I have not felt this good for quite a number of years. F 52 1 years
.125 1X day
8/18/2010
 1  Elevated Thyroid Levels SEVERE moodswings (sometimes get so aggravated I couldn't stand myself!), restlessness, sleeplessness, chest pains, constant flushing feeling, pain in back, head, and limbs. These are just the major things... I took the generic form of the drug. I would rather put up with the three month long menstral bleeding, weight gain, hair loss, depression, etc. than go through what this medication has put me through in the past few days. I can't wait for this to be completely out of my system! F 31 2 days
75 mcg 1X day
8/16/2010
 1  Thyroidectomy due to goiter rashes, swollen abdomen, depression, lack of energy, mood swings, bottom of feet sore all the time, Fibromyalgia, 75 lb weight gain I have been on a roller coaster ride with synthroid the past 17 yrs and I vow never to take it again. Quality of life matters!!! I switched to Armour plus I take narural supplements, yoga, hiking, healthy diet. I am slowly losing weight & symptoms are starting to go away after a month on Armour. Find what works for you. I find balancing things out with natural stuff helps. F 48 17 years
200 mcg 1X day
8/14/2010
 5  thyroidectomy NONE LOVE IT !!! It has given me my life back. before they removed my thyroid I was sleeping 12 to 14 hrs a day and hated life. Now I'm cancer free and loving life again. M 46 21 days
150mcg 1X day
8/13/2010
 2  complete thyroidectomy brain fog - couldn't make a decision, irritated alot, excessive sweating especially around head and neck had a left thyroidectomy 20 years ago due to a cold nodule - the surgeon then felt the whole left side needed to come out. Had the right side removed 90 days ago due to another cold nodule and a goiter, having pressure on throat, wheezing when sleeping. Went to an endocrinologist who had no empathy at all. Insisted I use Levoxyl - had a very bad stiff neck and headaches from that not to exclude the brain fog - I can handle most of the other symptoms but not that - I need to think clearly and couldn't. Then asked for Synthroid (he didn't want to put me on generic because he felt the dosage was too off). I stayed on that for a month before surgery and then for 1 month after surgery when I decided I needed to try something that would not give me the brain fog. Had been on generic before and didn't have problems from it. Called him, talked to his assistant (waste of time ) and he never called back. Talked to primary after that and she will prescribe but I do need to do the tests after a month. Will do. Brain Fog is gone , feel so much better. Anyone who has hypothyroid needs to get the book The Thyroid Diet by Mary Shomon. She will clear up what the doctors won't. Hope to eventually go on Armour after the blood tests. F 59 3 weeks
.125 1X day
8/13/2010
 1  hypothyroidism - recommended by dr rapid weight gain look at natural vs. synthetic alternatives F 44 5 weeks
115 1X day
8/11/2010
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 5  hypothroidism none My four sisters also take this drug with no side effects. F 55 20 years
112.5 MCG 1X day
8/9/2010
 1  Sub Clinical Hypothroidism Difficulty breathing, tightening of the chest, trembling, dizziness After a few days on synthroid I was feeling great, but one week after I starting taking I felt sick and dizzy. I had an almost panic attack like episode (without the panic or fear) following the symptoms in the morning. I was told at the hospital that I may need to reduce the dose, or only take this medication every second day. When I went to see my doctor he denied that the medication could cause these side effects even if they are listed as he had never had a patient react to the medication. He said that I probably have an anxiety disorder that I developed a week after starting the medication even though I have never had any thing like this in the past. After stopping the medication I did not start feeling better for almost a week. I may have needed a lower dose or had a bad reaction to this drug. F 28 7 days
0.025mg 1X day
8/2/2010
 1  Hypothryoidism Severe Weight Gain...75 pounds over the two years... Docter kept changing dosage.. I exercised with a trainer.. dieted.. nothing worked.. had my metabolism tested.. I know it was this drug that made me huge! Now here I am trying to lose this weight.. new doctor just put me on Armour.. three months.. dose to low..just increased it again.. I wish I would have found this site earlier.. doctors only think you are gaining weight because you must be eating too much.. Bull Crap.. its this darn drug! F 39 2 years
175 1X day
7/29/2010
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 1  evaluation of blood levels I followed the directions implicitly by taking the 50 mg on an empty stomach before breakfast. Anxiety and depression filled my day and I felt like I was wandering through a dark fog. I called my Doctor and she said that these were not normal side effects. I am thankful to have found this website because it let me know that many others have had the same problem. This was prescribed for me only because of a slight variance between my T3 and T4, and not because of any noticable low thyroid symptoms. I did not take it this morning after reading others' experiences and will not ever plan to take it again. I called the pharmacy and they did verify it was a synthetic. F 57 3 days
50 mg 1X day
7/28/2010
 5  thyroid cancer It takes a 6 month period of adjustment every time they change the dose. Then it works well again. F 58 13 years
137 1X day
7/27/2010
 3  Slight Hypothyroidism Decreased cold intolerance: i.e. stopped having to wear three layers of clothes on a cool day and still feel cold to the bone. With a new doctor's help, I switched to Armour Thyroid (a T4 and T3 combination medication). I was told it is critical to treat me based on symptoms and not hold fast only to test results. Since I started on Armour I feel like my depression has lifted and I want to live again. I am not sure if I had negative side-effects on Synthroid after two years, but I know that my mood and energy levels got worse over time. It may be dosage related. There are many doctors out there, though, that stick too much to test results rather than how you feel. The Thyroid is such a powerful organ and regulates so many things in your body such that when it doesn't work properly, you can get depressed, gain weight, have more pain, increased appetite, etc., etc. If you don't like your doctor or how you feel on Synthroid, see someone else for another opinion. If you have to see 10 doctors until someone takes you seriously, then do so. You should not have to suffer. F 41 2 years
50 MCG 1X day
7/21/2010
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 3  Thyroid cancer, TT Vertigo, hair loss, weight gain, severe peeling and flaking on the top of my lips only, heart palpitations, swelling of hands and feet, phantom symptoms of a female heart attack (left side numbing, headache,stabbing pains in middle of shoulder blades).These symptoms were caused by a spike in my blood pressure due to Synthroid- I do not have high blood pressure ever. My thyroid was not high or low before my surgery, nodule only. TT 1 year ago due to a small nodule that was benign in 06 and started growing after a family death (stress). It turned out to be cancer, early stages. Had Iodine radioactive treatment 1 month later. I know my body is recognizing this is a synthetic med and is not producing on it's own- it's rebelling. My Dr. says my levels are great (he's keeping me a bit high), however,I know my body well and everything is off. Annoying and frustrating. With the phantom female heart attack symptoms, I had to call 911 which was so frightening. It's important to note I did not have any thyroid problems before my surgery, it was taken out due to the nodule that was growing. F 50 1 years
175 mg 1X day
7/9/2010
 5  Total Thyroidectomy Brain fog on 125mcg, Sweating and heart palps on 137mcg Attn: hasimoto's patients who are disatisfied. Please understand you have an autoimmune disease. I suffered from Hashi's for 12 years with no thyroid meds and suffered the same symptoms all of you are describing. do not be afraid of thyroidectomy, GET IT OUT. As long as you have a diseased gland in your body, meds or not you will have these symptoms. If you have Graves, do not be fooled by RAI, the diseased gland is still in your body. Please see all the positive comments from other TT patients on this site and make that decision for yourself. I FEEL GREAT on synthroid and no more diseased gland. No more symptoms...I have my life back. I worked with my endo and am now on alternating day therapy. Results: perfect!! F 41 6 weeks
137/125 1X O
7/4/2010
 2  Hashimoto's Thyroiditis/Hypothyroid Anxiety, muscle weakness, shakiness, some tingling in hands and feet, additional fatigue and depression This is my second trial of Synthroid. For my first trial, I took generic levothyroxine (25 mcg) for approximately 3 weeks. Symptoms did not improve, muscle weakness was terrible, anxiety led to panic attacks, and toward the end of the first trial, I experienced extreme joint pain in hands and feet. Endocrinologist recommended that I try name brand Synthroid (starting on lower dose) because I may be sensitive to binding agent in generic brand and/or I may be sensitive to medication in general. So far, I have experienced similar symptoms (with less tingling in hands and feet), but anxiety, depression, fatigue are not going away. In fact, those three symptoms are worse than prior to both the first and second trials. If symptoms continue, I will stop taking medication, as Free T4 and T3 are still within normal range, but TSH was high at 7.8. I have signs of hypothyroidism and TPO antibodies are >1000, but Synthroid may not be the best choice for me. My next step will be to find an endocrinologist, Naturopath, or other to prescribe natural brand (e.g. Armour Thyroid). Many books and websites suggest that natural brands may work better for people with sensitivities/side effects from taking synthetic brands and/or T4 to T3 conversion issues because they contain both T4 (inactive) and T3 (active) thyroid hormones, in addition to other hormones (T2 and T1). F 31 5 days
12.5 mcg 1X day
6/29/2010
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 2  Hypothyroidism/Thyroidectomy Weight gain (25lbs total), dry eyes, blurred vision, ringing in ears, joint pain, dry skin, constipation, bloated, digestion issues, extreme fatigue, lack of concentration, extreme anxiety. Was originally on .50mg, then up to .75mg, then back down to .50mg when I insisted that my doctor supplment the Synthroid (T4) with Cytomel (T3) because my symptoms were getting worse even though he felt I was fine due to my TSH lab results. Doctor insisted the Cytomel wasn't going to help, but finally agreed to prescribe 5mcg Cytomel 2x/day. First 2 weeks were great and most of these symptoms disappeared, except for no results with weight loss. I was actually gaining again. So I decided to come off the Synthroid and stay on the Cytomel to see how I feel on that regime. It has been 5 days w/o Synthroid and just Cytomel. I feel great so far. I might have to convince my doctor to increase my Cytomel dose on the next visit, but anticipate a struggle as he didn't want to prescribe it in the first Having thryoid disease is a woman's curse. Even more frustrating is dealing with doctors who go off your lab results versus how one actually feels. And to top it off, they will tell you it's all in your head as you fight to feel human! Guess that is too much to ask for! If it were not for my tenancity and research into my health issues for over a decade, these doctors would have me on tons of different pills to treat symptoms -- not the problem itself. It is sad how widespread this thyroid issue really is and how many lives it can destroy as it affects your whole well-being. Keep searching for answers. Don't give up! F 43 3 years
.75mg 1X day
6/28/2010
 4  removal of thyroid Not sure, had some tension type headaches, and such, but am taking it and cytomel and it has lifted my depression and all. I was taking a generic brand for nearly 15 years and was undertreated. The headache bothers me. I guess I just have to hang in there. Maybe the headache will go away. F 40 2 weeks
100 mg 1X day
6/26/2010
 3  Total Thyroid Removal due to Cancer constipation, swelling and pain in lower legs and feet I felt great after surgery on 75mgs of synthroid. The only side effect I noticed was that my feet were more tender on the bottom. I was off synthroid for 1 week during RAI and then the new Dr. put me on 137mg. After RAI I had a lot of swelling in my lower abdomen and legs. I assumed it was the RAI. It has been 2 months since RAI and the swelling in my abdomen has gone but my lower legs and feet continue to swell. I am also having problems with constipation that I did not have at the lower dose. The Dr. says that my numbers are fine and will not do anything else. The people I talk to on fb who have had thyroid cancer and rai have not had these problems with thier legs and feet. F 50 5 months
137mg 1X day
6/23/2010
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 3  Graves I had Graves many years ago (1993) and took Syntrhoid since then. A month and half ago, the TSH came out very low 0.04 and the doctor took me off Synthroid for a months. After a months the TSH came out very high (53) so I started taking Synthroid again, low dosage (0.075) but after 2 weeks of taking it I feel very nervous and not myself. I cannot remember how I ajusted to the dosage after I was treated for Graves but now is very difficult for me, experiencing nervosness and insomnia. Any advice is very much appreciated. F 55 12 days
.075 1X day
6/21/2010
 2  hypothyroid weight gain!! switched to cytomel (generic) lost the weight and got the same desired TSH level F 57 1 years
100mg 1X day
6/20/2010
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