ZOMETA Reviews (ZOLEDRONIC ACID)

Average Rating: 3.0 (14 Ratings)

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 CALCIUM METABOLISM

 Type: Rx Drug

  

ZOMETA  (ZOLEDRONIC ACID):  This medication is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Zoledronic acid is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and other types of cancer (such as breast, lung) that have spread to the bones. Zoledronic acid belongs to a class of drugs known as bisphosphonates. It lowers high blood calcium levels by reducing the amount of calcium released from your bones into your blood. It also works by slowing the breakdown of your bones by cancer to prevent bone fractures.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOMETACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Osteopenia from Estrogen blockers I'm still taking this medication. I'm taking the infusions every 6 months and having a fluid bolus prior to the infusion has completely eliminated the pain issues. Still haven't been rescanned yet so I do not know how well it is doing what it's supposed to do which is why I can't give it any more than a middle of the road rating. F 60
30 mg 1X O
4/2/2024
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Patient History
 4  osteoporosis from Anastrozole No noticeable side effects so far. I get a 20 minute infusion every 6 months and just completed second treatment. I am told it will help prevent BC recurrence and rebuild my bones. I have not had dexascan to see if it is helping yet. I have been on Anastrozole for just over a year also. The dentist did remember to ask me if I was still taking this drug. Since I was not having root canals or any other dental surgery it was a non issue. F 59 1 years
4 mg 2X O
10/30/2023
 2  Breast Cancer After first dose I was In so much bone pain. I had chills difficulty breathing and it lasted a couple of days. Told my onocologist and she seemed surprised. I also take Anastrozole daily and Zometa every six months. I have been doing this for 4.5 years. Since being on these medications I have had 2 kidney stones removed in the last 2 years. My bones hurt all the time. I wake up in pain constantly. I have made the decision to stop the Zometa. I don’t know if the kidney stones or the bone pain is the result of these medications but I feel it is the cause. F 71 4.5 years
1X O
5/26/2022
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 3  2b breast cancer -preventative of m 12 hours after infusion woke up in the middle of the night moaning of pain all over my body. Chest felt tight and I was warm. This pain lasted 12 hours but a mild ache has lasted 4 days so far. Tiredness lasted for 3 days too. Going through it, I wasn't sure I would repeat it in 6 mos. It was rather short lived so I may continue. I just need to plan for side effects or find helps. Not sure if you can take pain meds but I took excedrine for head and neck ache almost at the end. F 48 1 days
1 small i
9/21/2015
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 2  Stage IV BC mets to bones Unable to walk a day after treatment. Extreme pain in feet, legs, arm, shoulders and hips. Right foot felt crippled. Nerve pain and burning down leg and in foot. Had to use a "walker" to get around - on 3rd day of these side effects after 2nd treatment in 4 weeks. Also was on Femara but doctor took me off it as side effects were even worse. I might try a smaller monthly dose to see if it lessens these awful side effects. I feel I have to try as I have 5 tumors in various bones from mets breast cancer. F 63 30 days
4 mg 1X M
10/24/2010
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 1  Bone Mets from Breast Cancer Flu like symptoms, edema in legs and feet, fever, fatigue,kidney pain. I have been on both Aredia and Zometa. I was advised recently that current research shows a correlation between long term use of Zometa or Aredia and the development of kidney stones. My kidney stone condition is quite painful and ongoing. I am now under the care of a nephrologist and am trying to determine if there is permanent damage to my kidneys. F 57 8 years
1X M
7/9/2010
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 3  2nd Breast Cancer - Stage 1a Given bi-annually. First time was last July 2009. Fine the day of infusion - then went to bed that night and was hit with SEVERE chills [teeth chattering with three comforters on me in the middle of the summer] which turned out to be the onset of a fever that peaked at 102.9. Fever broke the next day in the afternoon. Then for the next 2-3 days, muscle aches and extreme fatigue. ONC said because of age [too young] that was why it was so bad; but promised that it would only happen for the first dose. I had my second dose last week. Fever of 100 for a half an hour immediately after the infusion then the fever broke in the next hour and then I was fine. Muscle aches - mild. Fatgiue and malaise - extreme. Make sure you get your dental work done first before the infusion. Any drilling could cause jaw necrosis. F 39 6 months
1/24/2010
 4  Osteopenia After first infusion, experienced mild flu-like symptoms beginning about 24 hours after infusion, lasting about 2 days. Taking Femara since early stage breast cancer (lumpectomy and radiation) 3 years ago. Dexascans show 8% and 5% bone loss over the next 2 years due to menopause and/or Femara side-effects. Too early to know benefit yet. F 53 2 weeks
12/10/2009
 4  Stage llb Breast cancer, I had my first infusion of Zometa 4 weeks ago and didn't experience any side effects. No flu symptoms, no aches or pains. I had a very slight fever that was gone within 12 hours. But no other symptoms. I had stage llb breast cancer 3 years ago. I'm in remission now after(mastectomy) chemo and radiation. I took Tamoxifen for 2 years and am now taking Arimidex. My oncologist put me on Zometa(one dose every 6 months) because I am osteopenic and she said that new studies have shown that it helps reduce your chance for recurrance. I feel pretty good and if it helps keep me in remission, then I am all for it! F 48 4 weeks
11/19/2009
 4  early breast cancer - prevention Had first infusion two weeks ago, and experienced the expected flu-like symptoms the next day. Since then, I don't notice any side effects. I am on a lot of meds, so it is hard to tell, but I think all is well. I am taking infusions of 4mgs every six months. I declined chemo and radiation following a double mastectomy (one breast and three nodes involved) and am taking Tamoxifen and Lupron, so Zometa is my insurance against future recurrence to the bone. F 41 2 weeks
7/3/2009
 3  Drug trial for breast cancer I am on a monthly infusion of 4 mg (?) (via i.v.) and experienced very difficult breathing, chest pains, and high fever/chills/flu symptoms the first time around. My oncologist then gave me dexamethazone (steroid) to counter and this works wonderfully. I get it the day of in the infusion and expereience very little of those side effects as a result. I am also on Effexor and Arimidex so hard to know if some nausea, numbness, and fatigue is a result of either of those. I rate it 3 as it is unknown as to its effectiveness for my purpose. I am on a 3 year trial to determine if this drug will help prevent bone metastasis for breast cancer. F 45 4.5 months
6/22/2009
 4  stage 4 breast cancer to bones Usually after treatment, for a couple days feel as if I am getting the flu then I have the best week of the month is the first week after treatment, Achy bones, joints, feverish, tired, just like getting the flu. i think I would be in terrible shape if not taking zometa, I believe it helps me with my pain and even gives me a little zing every now and then after treatment. F 48 4 days
5/5/2009
 4  Breast Cancer with bone mets Very stiff ankles and feet and to a lesser degree wrists and fingers which only started about 6 months into treatment. I feel like I have lost a lot of agility and am wearing a suit of armour. Overall though I am pain-free despite the fact that I did have pain in some places where I have lesions ie spine, ribs before treatment. I make sure I go for a 45min-1hr walk each day. I find being mobile helps stiffness. I think with my advanced disease I would be so much worse off if I wasn't on Zometta. I am about to start on Femara which I have read can make joint pain much worse. So fingers crossed. F 39 7 months
10/24/2008
 2  breast cancer stomach pain, nausea, constipation, tiredness, weakness F 65 35 days
9/15/2008
  

ZOMETA  (ZOLEDRONIC ACID):  This medication is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Zoledronic acid is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and other types of cancer (such as breast, lung) that have spread to the bones. Zoledronic acid belongs to a class of drugs known as bisphosphonates. It lowers high blood calcium levels by reducing the amount of calcium released from your bones into your blood. It also works by slowing the breakdown of your bones by cancer to prevent bone fractures.    (Sources: U.S. Centers for Medicare Services, FDA)

     

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