AVANDIA Reviews (ROSIGLITAZONE MALEATE)

Average Rating: 2.0 (99 Ratings)

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 Type: Rx Drug

  

AVANDIA  (ROSIGLITAZONE MALEATE):  Rosiglitazone is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Rosiglitazone belongs to the class of drugs known as glitazones. It lowers blood sugar by helping to restore your body's proper response to insulin.   FDA Approval Date: 1999-05-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR AVANDIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Insulin Intolerance Weight gain, water gain, did o.k. on blood sugar, but not in the morning. Is not consistent. F 51 5 years
5/19/2007
 1  type II diabetes while hospitalized I was administered Avandia as a protocol medication. The clear fact is that it should never be given to someone who previously had congestive heart failure. After two years, I began having adverse reactions: Swollen feet, edema, peripheral neuropathy, extreme difficulty breathing (very low oxygen saturation - 68%), sluggishness, can't walk, extreme weight gain, hair loss, almost died from lack of oxygen. Only way to stop symptoms was to stop taking Avandia, and to detoxify my body. Look into detox with oil swishing, best method for me. I was able to recover my breathing within a two week period. Was on supplemental oxygen at the time. It took taking all this information to my Pulmonary doctor, who recognized the problem with my breathing and had previously stated that I would never recover nor be able to take me off the oxygen. When he saw the side effects, and the documentation on Avandia, he was shocked. Was also surprised when I came in without the oxygen. He ran tests, and is now recommending the detox to his patients. M 51 2 years
5/17/2007
 2  type II diabetes Highs and lows in blood sugar levels. Has anyone experienced lymphodema in the stomach? I have large "blisters", skin is turning hard and am gaining weight in girth. Can hardly walk because of the extra weight. Is this worth it? M 54 4 months
3/21/2007
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 3  insulin resistance I have had severe weight gain. Within one year I have gone from a 16 to a size 22, all while taking aerobics and watching what I eat and drink. I was having menstrual bleeding almost on a daily basis. The nurse practitioner thought my hormones were out of wack and told me I needed an IUD. With that I gained 16 pounds in 6 months. After having that removed, I still can't lose weight despite the fact that I am still taking aerobics and cut out sodas and other fats. It seems that I am just continuing to gain weight with this drug. I have also just recently started having chest pains. The doctor did a EKG though and found that my heart is okay. The only good thing is that my glucose did come down and I don't have the craving for sweets like I used to. Do I really think that it is worth all that? Not really. I think there are some good herbal medicines to take like Bitter Melon. F 36
3/20/2007
 2  Type II Daibetes Extreme hair loss, no weight loss Asked doctor for an alternative because of extreme hair loss. Hair is coming out in hand fulls. My hair was very thick and plentiful. Now I have bald spots. It did low blood sugars. Hope new medicine stops the hair loss and still controls the sugar; scary. Weight has not come off easily. I work out 5 times a week, stay on a controlled yet healty diet, and drink plenty of water. I was loosing about .3 lbs per week. Doctor said this was good considering it is a weight gain medicine. No other side effects. F 37 3 months
3/20/2007
 3  Onset of Diabetes My side effects set in during 3rd month of 8mg treatment daily. Heart rate skyrocketed, woke me up at 3 a.m. with 115 HR! I went to doctor and reminded her I was a PCOS patient (undiagnosed) and this could be too high of a dosage? At first I'd lost weight and was feeling great, then in February, I ovulated, gained weight (popped a button off my jeans!) and started to have blood pressure/HR problems, fatigue, nasty attitude due to "strain." We'll have to see how this plays out. I called a pharmacist and took only 4 mg of Avandia along with 5 mg. of glipizide...BP going down, HR dropping: in ONE DAY! This is touch and go. I think it is a very good drug...I was in sugar range of 360 in December...it was 101 on Feb. 23 and 147 Feb. 26. F 57 3 months
2/26/2007
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 1  sugar diabetes took avandia for a year and half filled up with fluid and couldnt breathe felt like i was dying. went to cardiologist and immediatly took me off avandia. gave me very potent water pills and a heart drug. now dr gave me actose and i am so scared it will do the same. tried the new pill januvia and got a terrible sore throat. F 68
2/17/2007
 1  Type II diabetes Upper respiratory infection and extremely painful muscle spasms in chest. Headaches. Painful swelling in both upper arms to the extent of almost total loss of movement. Avandia is 4mg daily along with 2000mg metformin and 11mg glyburide. hypoglycemia often with 1.2 being the lowest. Just had glyburide lowered to 10mg 2 days before submitting this sugars are between 4.5 and 7 even with the lozenges i've been using because of the dry mouth and throat, also lost 10 lbs, which is good and not a complaint at all. I am certain it caused fibromyalgia pain to grow in intensity. I "used" to only take 4, 200 mg of ibuprophen daily to control that pain but am now on prescription for codiene and antibiotics. I see the dr tomorrow 01/31/07 and will definitely request to go off of avandia. I have a high level of pain tolerance "normally" and find that I am getting depressed because of the increased and more constant pain. F 51 3 months
1/30/2007
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 1  Type II Diabetes In July 2006 I went to personal physician and kidney speciallist. At that time I was suffering from Swelling of the feet, ankles and legs, extreme sluggishness, and heavy feeling in legs up to mid thigh. I was put on Lasix, 40 mg/day. Condition continue to worsen so that by 12/25/06 I suffered from extreme fatigue as well as bilateral kidney pain and pain in the groin area as well as muscle soreness in thighs. Read the side effects listed here 2 days after Christmas and immediately stopped taking 4mg/day of avandia. Starting 1/12/07 have also put myself on a no carbohydrate diet. Have lost 10 pounds altogether and feel much better. I have none of the symptoms that I listed above. None. I may tell my doctor this when i see him in March. I may also experiment with stopping the Lasix. M 63 18 months
1/29/2007
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 1  type 2 diabetes swollen feet, painful foot joints, higher blood sugar, severe muscle pain This drug made me feel awful and didn't lower my sugar. It seems I got almost all the side effects, which hurt and made my life miserable, since I dance and was unable to. F 58 2 weeks
11/29/2006
 2  Type 2 Diabetes I have been on 8mgs. for 3 years and during that period experience a 20 lb. weight gain and water retention especially in my legs. It was so bad I could hardly walk. There was a mix up in my insurance and I was without the drug for 3 weeks. What a difference! I started working out 3 times a week, am losing weight, I'm eating correctly, I was happy until I started it again last week. My quality of life has again gone down hill with the nausea, etc. I am going to discontine the drug and continue to watch what I eat and see what happens with the next A1C test. I was on Avandia only because I can't take Glucophage which I guess is the drug of choice. F 61 3 days
11/10/2006
 2  to improve reception of insulin swelling of the feet and ankles, sluggishness, heavy feeling in legs, heart flutters, irregular heart beat and extreme fatigue. I cut my dose from 8mg to 4 and have noted improvement to some degree. I may try to lower bl sugar by weight loss to stop altogether. I also noticed bad infections with mrsi methicillin resistant staff infections, for which leviquin was adequate to eliminate and which was a result of abnormally high blood sugar. I'm getting more afraid of avandia , it is no longer getting the job done and its negative effects appear to be cumulative. have there been any known deaths from avandia due to heart irregularities. M 66 4 days
10/27/2006
 5  Psoriasis (non-diabetic patient)) NONE Outstanding result of treatment using Avandia + single injection triamcinolone. 12 years of topical treatment (Elocon, Dermol creams) had only resulted in progressive total-body psoriasis. I cannot speak too highly of Avandia/triamcinolone as a "Deliverance" from the Hell which is psoriasis. M 79 2 days
10/14/2006
 1  High Blood Suger I went Blind-20/400 vision Notice--if you know anyone Blind that takes the Drugs-Actos or Avandia-Please spread the word THESE DRUGS CAN CAUSE YOU TO GO BLIND In Jan 2000 I was prescribed 15 mil per day Actos-in a few months it was raised to 25 mil per day-in Oct 01 it was raised to 35 mil-in Aug 01 I had a light stroke in NOV 01-vision got very blurry. My Dr sent me to a Dr of Ophthalmology, Tulsa, OK-the Dr stated, we can fix this, you got to me in time. We started Lasers, 3 treatments in left eye & one treatment in right eye, vision got worse. Now I had Cystoids Macular Edema. Shots in the eyes 2 in right & 4 in left of Kenalog. About July 03 my medication was changed from Actos to Avandia. Since Kenalog can worsen cataracts, I had cataract surgery on left eye Dec 24th 03-it was wonderful I could hardly waite to get right eye done. Jan 04 we done cataract surgery on right eye--My vision was 20-20-BUT-only for a few days!! The swelling had come back. On Jan 6th of this year I was watching the l M 57 3 years
9/13/2006
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 2  type 2 diabetes started on Avandia 2mg twice daily [1month]. I began suffering from triedness ; fatigue; muscle pains and shortness of breath. I go to gym twice a week - and I am exhausted after a "light" workout. sugar levels are well controlled with avandia and diet and keeping fit [but keeping fit is getting harder to do - due to the fatigue] M 44 1 months
9/8/2006
 1  Type 2 Diabetis On it for approx. 4 yrs (took .6mg three rimes/day (heavy dose) I have no doubt it caused........ 1. swollen legs, ankles, and feet. 2. weight gain Had to get by on ONLY AVANDIA (anaphlactic shock from Glucophage)--Tookapprox a month to really "kick in" Then kept sugar nostly in middle 100s. After first year--developed BREATHLESSNESS which has become extremely worse with next two yrs. In hospital for minor surgery one yr ago (unrelated). CT CHEST, Echocardiogram, heart monitoring--esentially normal. Since then-CUT Dosage down to .4MG EACH AM AND pm. ALL LEG-ANKLE-FEET EDEMA-GONE COMLETELY. oNLY HALF AS BREATHLESS NOW. nOW i AM READY TO FIND SOMETHING ELSE-SO i CAN GET RID OF THE BREATHLESSNRSS. question---aNYONE ELSE HAVING bREATHING PROBLEMS?? a F 60 4 days
8/30/2006
 3  Type II Diabetes Initially mild swelling of legs, then gradually increased to moderate swelling. Tiredness of legs. Increased infections Blood glucose control was good HbA1c last was 6.25mmol/L. I did experience elevations in sugar in am but dividing 8mg into twice daily 4mg helped. GP has suspended my Avandia for a month and put me on Glucophage 500mg three times daily. I see no noticeable changes in blood sugars on Glucophage and my ankle swelling has disappeared. Since holding my Avandia (5 days ago) I have lost 3lbs in weight I assume this was from retained fluid. I am seriously considering not re-starting Avandia after the month is up, especially if there is no difference while using Glucophage. The other consideration too is the vast difference in drug cost for Avandia vs. lucophage M 56 3 years
8/29/2006
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 3  Type II Diabetes Swelling of the ankles. Weight gain. I was taking 8 mg per day Avandia for several years, along with glyburide and metformin. Two years ago I began taking insulin, and dropped the glyburide. Last week my endocrinologist finally agreed my ankles were swollen (they had been swollen for years), and told me to cut back to Avanadia 4 mg/day. I am hoping I can eliminate the Avandia completely and just increase the insulin a bit. The only disadvantage might be loss of the benefit to serum lipid levels due to Avandia. M 45 5 years
8/7/2006
 2  "profound insulin resistance" Swelling of ankles, no weight gain. (I do not have diabetes, perhaps that explains why no weight gain.) Have been on the medication for 18 months. It worked great at first, but now it hardly helps at all. My doctor warned me it would have a diminishing effect, and I would have to increase dosage now, which I am reluctant to do. Has anyone tried discontinuing Avandia and then restarting it to see if full effects can be regained? Also, see new health warnings re Avandia's effect on vision. (Google "Avandia vision" for results re this.) New medications similar to Avandia are in the pipeline: Acomplia is one, though it is still not approved by the FDA. (Google Acomplia AND "insulin resistance" for more info.) F 55 18 months
6/20/2006
 3  Diabetic Type II Blurred Vision, Swollen Ankles Took about 6 - 8 weeks to begin working a bit. F 33 5 months
6/7/2006

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