VAGIFEM Reviews (ESTRADIOL)

Average Rating: 2.4 (300 Ratings)

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 Type: Rx Drug

  

VAGIFEM  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   FDA Approval Date: 1999-03-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15


RATING  REASONSIDE EFFECTS FOR VAGIFEMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Bladder Stomach ache but doesn't last I feel well on it and my skin is looking amazing. If I had a lover he'd be a Happy man! F 72 3 weeks
10 2X W
1/6/2024
Email
 1  Vaginal dryness Irritated bladder pelvic pressure headache nausea and awful stomach pains and diarrhoea Couldn't continue beyond 6 days I had stomach cramps from the first day which just increased the more days I used it by day 3 had terrible diarrhoea, this is my 2nd attempt at using this and it did exactly the same 1st time soI know it was the vagifem will never use it again I feel so unwell hoping it settles soon F 50 6 days
10 1X day
12/14/2023
Email
 5  Painful intercourse/itching None F 56 8 weeks
10mcg 3X W
8/13/2023
Email
 1  UTI The most intense abdominal and back pain with a constant and painful need to urinate all the time, often waking me in the night. The pain became so bad that I visited the ED. A CT scan brought up a large ovarian cyst which I knew I had but had increased in size. I now wonder if this could be due to vagifem. Almost a constant headache and feelings of low mood as though I was very disconnected from my life. It sounds dramatic but I really thought I had something very wrong with me. I cannot tell you how grateful I was to read how other people felt on this terrible medication. I have no clue whether it even helped with the original symptoms I took it for as the side effects were so awful I thought I was dying!!! It should not be allowed to be prescribed without warnings of the side effects. I feel as though I have been poisoned. I stopped taking it after 10 days and can not wait to feel my normal self again. I will also be going down the natural route from now on. I never want to feel like this again. F 52 10 days
10 1X day
5/14/2023
 1  Was told atrophy by Gynae, bladder Swelling, burning and pelvic pain hair loss. Had hysterectomy 25 hrs ago. Now have bladder prolapse. Have followed medical instruction but concerned about using at 75 F 75 12 months
10mg 3X W
5/9/2023
 1  vaginal atrophy Headaches, sudden onset of UTI symptoms, abdominal heaviness and bloating, cramps, mood swings. Didn't associate the UTI symptoms to vagifem as I get them often and had just recently come off medication for one and just thought it was flaring up again. Then found this forum and saw others reporting the same. Stopped treatment immediately and UTI symptoms went away. still experiencing heaviness in my abdomen but it's only been 3 days since stopping so hoping that goes away. I can't believe this medications is still on the market with so many negative reviews. F 59 7 days
1X day
4/1/2023
Email
 3  Soreness of the vagina area and dry Going to stop it I have stomach cramps almost every eve and spotting and something like periods it just made things worse F 61 14 weeks
20mg 2X day
3/30/2023
Email
 3  Soreness of the vagina area and dry Going to stop it I have stomach cramps almost every eve and spotting and something like periods it just made things worse F 61 14 weeks
20 2X W
3/30/2023
Email
 1  Vaginal atrophy After 1 dose I developed a bad headache, nausea and stomach pain. After reading all the negative reviews I have decided not to continue taking this drug. Especially as it may also cause hair loss. I'm surprised that such a low dose can cause so many side effects. F 55 1 days
10mg 1X day
3/10/2023
 1  Prolapse and premenopausal Been taking these now for 9 days ( advised to do 14 days then just twice a week So much abdominal pain like severe period pain, shoulder aches, feeling like I have uti, wanting to pee more, feeling like not emptied properly, blurred vision, skin itching, going to ring doctor tomorrow and advise Im stopping them Didnt look into this until pains started Im so worried as to what will happen next?? F 56 9 days
10mg 1X day
2/20/2023
Email
 1  Vaginal atrophy Breathlessness, increased blood pressure , dizziness , hair loss , weight gain , itching on body , extreme shoulder pain , headaches , palpitations Stupidly , I never associated these side effects with using Vagifem and never realised until I was diagnosed with atrial fibrillation and the dr suggested I might want to come off the medication. At that point I did my research. All of my symptoms disappeared but left with high blood pressure F 71 7 days
20mg 1X W
1/30/2023
Email
 1  Perineal soreness Headache Light sensitivity Backache Vaginal soreness Am going to try a non hormonal cream F 66 5 days
10 mcg 1X day
1/18/2023
 3  Vaginal atrophy, dryness Did loading for two weeks. Then took every other day, on recommendation. Gave me nausea,.loss of appetite, bloating, constipation, depression. Have now stopped using. This is my second time using. First time, I dropped to twice weekly and had horrible mood swings. I'm on an antidepressant already. F 53 30 days
10mcg 1X day
12/19/2022
 3  Urge incontinence Had to stop using Vagifem because of extreme hair loss on head and on pubic area, chest pains F 56 42 days
10 mcg 2X W
11/22/2022
 3  vaginal atrophy Some occasional stinging, but did give relief I develped endometrial cancer.........no other risk factors Question advisability of long term use F 75 12 years
1X W
11/4/2022
 1  Atropy vaginitist Had vagifem before on it 5 yrs came off started to experience vaginal discharge decided to take a break for a year .went back on it 4 days ago coming off it took a very bad reaction to it. Very bad swelling burning discharge. Would not recommend it for any woman . Would not recommend vagifem .something seriously wrong when a product can cause very serious side effects to a woman body. Manufacturers need to go back to drawing board if not prepared to do that it should be taken of the market F 60 0 days
1mg 1X W
9/27/2022
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 3  Urinary problems caused by atrophy OK for first 8 or 9 days then started with bloating. I looked pregnant. My abdomen, especially lower, was uncomfortable. I then started with what felt like gas pains and nausea. It was really bad to the point I was pacing around the bedroom. Lasted a few days. I stopped taking the vagifem and the side effects when away quite quickly. It's a shame as it had reduced some of the atrophy symptoms. F 51 15 days
10mg 1X day
9/24/2022
 1  Vaginal dryness This is the worse drug I have ever tryed, stomach cramps started within days, hot flushes and insomnia dispite being on systemic hrt for years, but the hell it caused was way worse than my symptoms for using it, my vagina got swollen itchy and hot, my vulva was beyond burning had to have an ice pack between my legs almost constantly, and to top it off I constantly felt like I had a uti eventually stopped and those issues went away. You are so lucky if you use this and its actually helps your symptoms, reading on here the majority suffer worse for using it, don't be fooled into using more thinking you need a bigger dose of it, the uti feeling was the worst it completely irritated my bladder I couldn't even sleep it was that bad, a horrible drug, when will these companies make a vaginal estrogen that doesn't cause so much irritation. F 49 5 months
10 1X day
9/18/2022
 1  Itchiness in vaginal area. I am writing on behalf of my daughter, as I feel puzzled for the gynecologist prescribed this medicine for my teenage 15 year old daughter. She decided not to take it, for all the risks involved with hormonal treatments. Have anyone faced any similar situation? Luckily we found other treatment for her promlems, but still as a mother I am feeling odd about the whole situation, how easily these risky drugs are passed to youngsters? I am glad that my daughter talked with me about it, she also got alarmed when she red the long list of side effects, and did not start using it though! F 15 0 days
10 1X day
9/15/2022
 3  Atrophy and frequent UTI infections When I first started vagifem I got hot flushes and fibroid re growth. The fibroids thankfully have receded, but over the past 2 years other symptoms have appeared, including night sweats, terrible intermittent nausea, much higher blood pressure. Tinnitus and random chest pains . I have had lots of hospital checks and blood tests, and nothing shows up so now I am wondering if this is all connected to Vagifem use. The reason is that I don’t have these symptoms everyday, so now looking to see if symptoms show up after using my twice weekly dose . There’s no escaping that Vagifem cured my UTI issues and certainly helped with Atrophy, but I notice that 2 years on the dosage is not working quite as efficiently. I am quite a bit tighter again in my vagina and a few burning sensations are occurring when I insert the pessaries. But my life is becoming a misery with these endless nausea attacks, which spurs anxiety and general doom and gloom . I have undergone so many tests including colonoscopy and nothing has been found apart from a couple of benign polyps. I have also recently started getting chest pains which just appear out of the blue and was sent to A & E by my GP 4 weeks ago and nothing was found ! Hot flushes and night sweats have also become a lot more prominent and I am 5 years post menopause ! I have also developed tinnitus and high blood pressure……seems very odd for all this to develop over a two year period . It’s a difficult call, but I am going to go back to my Gp to see if I can try something else . F 62 2 years
10 2X W
8/31/2022
Email
  

VAGIFEM  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   FDA Approval Date: 1999-03-26 (Sources: U.S. Centers for Medicare Services, FDA)

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