VAGIFEM Reviews

Average Rating: 2.5 (275 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR VAGIFEMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Vaginal dryness Migraine with aura, followed by debilitating headache, lower abdominal cramps. Will discontinue use and try a non hormone cream instead. F 59 2 days
10mg 1X D
11/8/2021
 3  Dryness lichen sclerosis severe atrophy Shooting pain in head.Some burning.slight weight gain.Mild feeling of internal fluid retention. Needs to be started before any prolapse gets worse. It won't reverse a grade 2 general pelvic prolapse. F 69 1 months
10 2X W
10/3/2021
 2  Menopause Back ache, stomach cramps, nausea, headache, calf pain, bloating, extreme vaginal swelling, frequent urination, intense burning throbbing and pressure around entire vulva Had uncomfortable tight dry feeling on vulva, given vagifem ( I am menopausal) although on systemic hrt still had this horrible feeling, two week loading was awful with above side effects, stomach cramps were terrible and bloating was bad I continued, things just got worse my vagina was completely swollen, whole of the vulva felt extremely tight sore, red in colour and horrible pressure feeling felt like all my insides wanted to push out, frequent urination became over whelming, so I stopped at 12 weeks, the vagifem seemed to create more problems and the issues I had became much worse, one week after stopping still have the swelling and burning, waiting for it to calm down then trying ovestin cream, if that fails I will resort to the ring F 50 12 weeks
10 1X D
8/8/2021
 1  Sore vagina, irritated bladder Within 2 doses, severe soreness around vagina and vulva, very irritated bladder felt like I had a uti, literally going for a wee constantly, hot flushes, headache, unbearable stomach cramps going into groin an hips, awful bloating, lower back pain, bad pain in left calf, nausea. I had a bad uti 8 weeks ago, treated with antibiotics, but was left with uncomfortable feeling in my bladder frequent urination, I also had hysterectomy 4 years ago no problems with bladder and dryness until now felt it might be vaginal atrophy so asked my gp for vagifem going off what I read on menopause matters website thought it would be the answer, since starting vagifem I've had all the side effects listed above, I cannot sleep due to the constant burning in the urethra and vulva and the constant urge to wee, was only mild before taking this, the stomach pain and bloating is completely unbelievable, I've now stopped using it, but will have to see how things go, I was going to stick with it as women on menopause matters suggest you do, but after 5 weeks I feel almost suicidal and extremely depressed the side effects are that distressing, trying to get appointment with gp but hard due to covid restrictions, my advice is this may well be excellent for some but not for everyone if after a month you feel this way stop using it and try something else, god awful I literally feel like someone has poured battery acid all over my bladder vulva and vagina, don't let others convince you to continue, as I have I wanted to quit at 2 weeks but carried on and now feel terrible hoping side effects ease soon F 48 6 weeks
10mg 1X D
7/5/2021
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 5  Vaginal dryness Increased sticky discharge Significant lubrication during sex It made a big difference to me being able to resume sexual relations after a multi year hiatus. Over time I have needed increasingly less frequently. Now I use one dose every 3-4 weeks without relapsing to dryness. F 67 3 years
10ug 1X AN
5/14/2021
 4  menopause symptoms No side effects apparently, but am also on tamoxifen which has many side effects, so may be attributing any to it instead. No more UTIs, no more dryness or urinary symptoms and sex is much more comfortable. However recently I feel aroused almost constantly, so thinking of reducing from 2 per week to once. Concerned about uterine problems and cancer in the area, so keen to stay on smallest effective dose possible as I tend to respond to very low doses of any medication. F 74 90 days
10mg 2X W
4/2/2021
 5  Atrophic vaginitis No side effects . Vagifem seems to have stopped working as I now have the soreness and stinging again. Awful. F 71 4 days
10mcgs 2X W
3/7/2021
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 4  Atrophic vaginitis No side effects Vagifem seems to have stopped working. I now have the awful stinging soreness again. F 71 4 years
10mcgs 2X W
3/7/2021
Email
 2  I am 67 years old I took vagifem 10 yrs I took it because I have lichen sclerosis when I was 50 I used until I was 65 and I stopped then I felt very dry and pain down there then I started again September 2020 in October I saw blood spot 4 times until January 2021 I stopped all February but I have and still the worst back pain cramps I did biopsy and ultrasound thank god I don't have cancer but I am typing and I have a terrible pain my lower abdomen and lower back I am 67 I went back to it after 2 years I had blood spots and I stopped and I strat to have back pain lower abdomen I am in pain now badly 67 0 days
1X D
3/2/2021
 2  I am 67 years old I took vagife 10 I took it because I have lichen sclerosis when I was 50 I used until I was 65 and I stoped then I felt very dry and pain down there then I started again September 2020 in October I saw blood spot 4 times until January 2021 I stopped all February but I have and still the worst back pain cramps I did biopsy and ultrasound thank god I don't have cancer but I am typing and I have a terrible pain my lower abdomen and lower back I am 67 I went back to it after 2 years I had blood spots and I stopped and I strat to have back pain lower abdomen I am in pain now badly 67 0 days
1X D
3/2/2021
 1  Vaginal dryness Acute debilitating lower back ache, extreme bloating, awful smelling gas, mental agitation, vaginal discharge. Yes I now have more moisture in the entire vaginal region but at what cost? No thank you! I will go back to coconut oil and increase frequency of sexual activity to keep the area in tune. Due to having CAD and HeFH I cannot take BHRT as I I wished to. F 51 8 days
10 mcg 1X D
2/16/2021
 1  Dryness / libido Didn't want to risk taking an oral HRT and doc said this was low dose and localized estrogen replacement , filled the script and tried it at 11pm before bed . Within half hour felt very unusually hungry . Went to sleep and had very erotic dreams and kept waking up with feeling of anxiousness ( usually I sleep like a log no kidding ) woke up finally and felt a little off , went about my day , felt wittier than usual and had strange energy , but still didn't like the way I had slept and was feeling next day so I decided to give up on it . Called pharmacy to ask if they would like the 19 sealed applications back and they said just dispose them . My insurance covered all but $20 so I'm not too worried about the $ but rather wasting this product after only using one . If anyone out there reading wants the remaining they can have for free just pay the postage to where ever you are and I will send them to you F 53 1 days
10mg 1X D
2/7/2021
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 3  Vaginal dryness increase libido Painful stomach cramps bloating and painful haemorrhoids . Felt pressure in the pelvic region. Felt like I was starting my periods again slight breast soreness. Seemed to really help at first but symptoms got worse the longer I continued to use it. This site would have been really helpful to see these reviews first. Doctor never even mentioned side effects which was only a telephone consultation due to covid, was ref to gyn clinic but thats been constantly postponed due to covid again may ask to be ref to a British Menopause Clinic although it will be out of area feel they will probably have more up to date info on this topic and look at just taking testosterone to get a normal sex life back although the gp will not prescribe as its not routinely prescribed for women. Thats why i have to go to a gyn clinic good luck ladies F 58 2 months
10mg 2X W
2/2/2021
Email
 1  Dryness low libido I thought the migraine was just because of a little stress yet I was getting fast heart beats anxiety The second day was even worse so I decided to google information. Honestly doctors just give out pills and don't really care about your symptoms!! Btw I had forgotten I have tried this once before and same problems !' Migraines are the worst ever!! F 57 2 days
10mg 2X D
1/29/2021
 2  Dryness painful intercourse Bloating, upset stomach blurry vision skin color change , diarrhea, lightheaded. Wish I knew more about this product before taking it! 58 0 days
10mg 1X D
1/26/2021
Email
 1  Vaginal dryness Palpitations, anxiety, frequent bowel movements. Lower tummy cramping, general unwell ness. F 63 4 months
10mg 2X W
1/14/2021
 2  Vaginal atrophy, chronic UTI I have bipolar 2 and it caused me to become increasingly depressed over the short time I took it F 46 7 days
1X D
12/18/2020
 2  Vaginal dryness Initial headaches which subsided, tiredness and flu like symptoms. On 11-12 day severe lower back pain and period pain although I have not had one for 6 years. Debilitating pain meaning I can't bend, lower or raise myself. A tiny amount of spotting. Extremely thirsty and feeling bloated. I seem to have reacted to Vagifem immediately and was happy to put up with headaches as my vaginal walls are much plumper and moist but the lower back pain and period pain is unbearable so I have discontinued use. I tried taking her tablets 1.5 years ago and developed a rash along with low moods. Decided to try vagifem as I want to have sex without suffering burning sensation and UTI's and as it is localised and supposedly low amounts enter the blood stream, I thought this would finally be the solution to post menopausal vaginal dryness. It seems I am extra sensitive to estradiol and sadly can't cope with the side effects. F 50 12 days
10 1X D
12/10/2020
 2  Dryness and UTIs Increase in blood pressure from 110/70 to 140/80. Headaches pins and needles in left hand and left buttock , and blurry eyes. Doc said wouldn't affect me . It did. Shame as the symptoms relieved but not worth the side effects F 56 12 weeks
10 2X W
12/4/2020
 3  Painful sex urinary urgency Severe bloating looked 6 months pregnant tiredness all the time Helped with urinary urgency but not worth the side effects. F 57 36 days
10 mg 1X D
11/21/2020
  

VAGIFEM  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   (Sources: U.S. Centers for Medicare Services, FDA)

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