COMBIPATCH Reviews (ESTRADIOL; NORETHINDRONE ACETATE)

Average Rating: 3.4 (163 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

COMBIPATCH  (ESTRADIOL; NORETHINDRONE ACETATE):  This medication contains 2 female hormones: an estrogen (estradiol) and a progestin (norethindrone). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. The progestin in this medication helps to reduce the risk of cancer of the uterus which can be caused by using estrogen. Women who have had their uterus removed do not need the progestin and therefore should not use this combination medication. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure). If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.   FDA Approval Date: 1998-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on COMBIPATCH: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR COMBIPATCHCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Balance estrigen Started 2/5/12 after one week lapse in estrogen only, on esttogenyou only for2 3 mos. This period of without hormones was a good test as MP symptoms returned. Night sweats, anxiety and skin crawling. On patch symptoms were rapid heart rate, some irritability, significant hair loss, fat increase middle, but gradually reduced heat, skin crawling symtom. Cut patch in half, doing better, some sex drive returning. Talk to doc next Monday. F 54 6 days
50/140
2/9/2012
 4  Hot flashes, Insomnia Still not sleeping, always hot, hair loss, bloating in the middle area, weight gain. F 56 2 years
50/250 2X W
1/21/2012
 4  menopause,hot flashes. Osteopinia no side effects at all unless the joint pain I am having is from them. I don't think it is. I teach aerobics and have been teaching over 22 years. I will say that since taking the patch my bone density numbers have increased A LOT but I have also been better lately about taking by Calcium. I have gotten more fat around my middle in last 2 years and I exercise very intensly 5 times per week...(minimum!) F 53 18 months
.05mg/.14m 2X W
1/14/2012
Email
 4  Hot Flashes and Severe mood swings My periods are back to normal. (I wasn't having regular periods prior to Combipatch for the last year) I like having periods, it makes me feel young again. I've also notice last month I felt the familiar pain of ovulating. My Hot flashes have decreased significantly and just 1-2 days prior to my new patch due date, they return In full force. AND as well as my erratic mood swings. Once I place a new one I feel great. I haven't had any hair loss, but my mid section has increased. I will try it for a year and then ask my Doctor what she thinks when I go for my annual next June. F 47 4 months
.05-0.14 2X M
9/6/2011
 2  Menopause primarly for night sweats Vaginal bleeding every day. Developed a month or so into start of it and never stopped, also developed an odor. Had to go off the patch, but bleeding still continued for a while after stopping. Nothing wrong per MD. So? Loved it because I could sleep well and moods were better, but I couldn't take the bleeding every day anymore, and the odor. Even though the bleeding was generally light, it was EVERY DAY. Put on stomach weight also. F 56 10 months
2X W
8/31/2011
 4  hot flashes, night sweats, dryness Starting to have hair loss, almost in clumps. Also, weight gain (middle area), some bleeding but tolerable. I started to apply 1/2 patch at a time in hopes that this would help and it has not. It has helped night sweats, and dryness tremendously but I'm afraid I can't live with the weight gain and hair loss. F 57 4 months
1X W
7/27/2011
 4  menopausal symptoms Weight gain in my belly. Feel bloated all the time. Have also noticed hair loss I feel more alert, have more energy, sleep better and the hot flashes are gone. I'm having a real problem though, with the belly & back fat that seems to come with using the patch. F 57 2 months
50/250 1X day
7/19/2011
 5  hot flashes,dryness,insomonia Weight-gain in hips and legs. I have been working out, eating right for 11 years, just to stay between 130-135, 5'8", and now can feel and see I have gained in my hips and thighs, the worse area I have been suffering anxiety with most of my life. I constantly am looking in the mirror and can't believe that I again, am one more time, annoyed that I still have to watch what I eat just to "HOPE" that I can wear my jeans. Honestly, does it ever end. Had the same problem with BC pills and used IUD in my 30's and 40's, which definitely relieved the weight gain. What more can I do?? I cannot go back to the way I felt, but this is so frustrating. Had the same problem with HRT oral meds, and stopped, but 3 years of non-hormone replenishment has put a toll on my well-being. F 58 1 months
50/140 2X W
2/12/2011
Email
 3  Flashes, mood, sleeplessness Hair loss, face bloat, weight gain This product greatly relieved all menopause symptoms, but made my irritable bowel syndrome worse. Tried controlling side effects by cutting patches in half, no help. The other side effects were unpleasant but doable; the worsened IBS was a deal breaker. F 51 1 years
50/140 1X W
10/21/2010
 4  hot flashes, loss of sleep weight gain, hair loss works well for my needs. Just dont know if the weight gain is pre-menapause or not, gained 10 lbs in a year, hair loss may make me wean off eventually. F 53 1 years
.05/.14 2X W
9/15/2010
 2  hot flashes..lack of sleep HAIR LOSS After being on the patch about 6 weeks, I noticed I was "shedding", It has gotten much worse, my hair looks terrible. Had my thyroid levels checked as I do take synthyroid...my levels were perfect. This is the only thing I've done differently and I feel it is the patch...It has totally stopped the hot flashes and I am sleeping so it is a bummer that I am starting to wean myself off. However, I would rather have flashes than lose my hair...I just pray it will grow back! F 56 4 years
50/140 2X W
7/28/2010
Email
 5  Hot flashes Major hair loss. It stopped my hot flashes but the hairs loss is really scary My doctor is doing blood work to see if it is related to my thyroid. F 49 7 months
0.05/0.14 1X W
5/12/2010
Email
 4  Menopause I feel as though I have gained weight and just overall blubber, since being on the patch. Could be menopause too, so who knows. One thing that has been disheartening is the hair loss/thinning I have experienced over the past year. My hair today is nothing it was 2 years ago. I have been to my Gynecologist & Dermatologist and they blame it on age. I am searching to find out if any CombiPatch users have experienced hair loss or changes in their hair. Otherwise the patch has been great and I haven't had a hot flash since being on it. I would prefer, however, to NOT be on it....someday, I suppose. F 45 1.5 years
.14 MG 2X W
3/7/2010
Email
 4  Irritablility, sadness, hot flashes Developed mean rash at application site after 6 months of use, I'm wondering if the dry, winter months have something to do with this. Spotty bleeding comes and goes. I'm going to try hydrocortisone cream, see if that works, and then I'll see my Doctor if it doesn't. F 49 6 months
1/15/2010
 5  severe hot flashes slight rash at patch site; controlled with hydrocortisone cream after patch removal It's saved my sanity--hot flashes and lack of sleep were completely debilitating. Used the patch for 2 years, gradually cutting it down (literally cutting it with a scissors) until I weaned myself off it. Within two weeks the hot flashes were back as bad as ever. Went back on it at 1/2 patch twice a week--still have very mild hot flashes mostly at night but it's a good compromise for me--hot flashes are largely controlled and my dose is low enough that I don't worry as much about the cancer risk (my mom died of breast cancer so I am high risk--but my quality of life was so wrteched with the hot flashes that I am willing to take the increased cancer risk). F 61 2 years
12/15/2009
 3  help body pains postmenopause Bleeding, both spotting and period-like bleeding, even after 1 year. Previous HT (climara patch + prometrium pills): had no bleeding, but depression and fatigue during progesterone cycle. Combipatch evens me out, reduces body(nerve) pains, increases sex drive and sleep hours. Bleeding is a problem, had several days of bleeding 9 months of 12; may try climara pro patch next. F 59 1 years
11/19/2009
Email
 3  symptoms of menopause cramps, breast tenderness, yeast infection, bleeding, bloating, stomach pain Helped my mental symptoms of menopause but I stopped using the Combipatch because of intense bloating, gas and abdominal pain. F 58 6 months
6/9/2009
 4  perimenopausal severe hot flashes None that I can attribute to combipatch... I was hallucinating from lack of sleep after months of 24/7 severe hot flashes, and went literally crying to my doctor to give me "real drugs"! Within 12 hours the hot flashes had COMPLETELY vanished and I called my Dr to tell him he was a genius. He claims this patch helps osteoporosis and he can tell women who are on the patch because they have less wrinkles. I probably shouldn't take it many more years, but for now, if I forget to change into a fresh one, the hot flashes start back up, so I obviously still need it. Supposedly it's "bioidentical" and safer than the old bad hormone drugs. F 47 2 years
3/5/2009
 4  Hot Flashes I have been using this patch for over one year. In recent weeks, I have had severe itching, swelling, and redness at patch site. It takes a good 2-weeks before I can apply patch to same area. I will be seeing my gynecologist to discuss this matter! F 59 1 years
1/5/2009
 3  POF Developed acne and unpredictable spotting. I have stopped taking this because my face started breaking out. Changing patch twice per week was convenient. The patch stays on fine and isn't uncomfortable. Does leave sticker residue on the skin, however. F 37 1 years
7/17/2008

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