REQUIP Reviews (ROPINIROLE HYDROCHLORIDE)

Average Rating: 2.8 (379 Ratings)

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 CNS, MISCELLANEOUS

 Type: Rx Drug

  

REQUIP  (ROPINIROLE HYDROCHLORIDE):  This medication is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). Ropinirole is also used to treat restless legs syndrome (RLS). It may improve your sleep by decreasing the urge to move your legs and decreasing uncomfortable/unpleasant feelings in the legs. This medication works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-09-19 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR REQUIPCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  RLS Almost instant cold like symptoms (no indicators of , headaches, eye swelling, instant insomnia. I have had RLS for about 5 years and doc advised doing the intro to Requip in interval dosages. The .25 and .5 made no difference and I didn't feel any changes, but when I hit the 1.0 I instantly got the symptoms above. I stopped immediately and thankfully I did after reading all of these comments. I am still getting over the bronchitis and other symptoms, but can say I would rather live with the jerking and twitching than go through this again. Would not recommend this to anyone, find another way. I was previously treated with Clorazepam (sp?) and that worked well. Will be going back to that once all of this clears up. M 34 7 days
6/4/2009
 3  RLS depression, anxiety, anger, restlessness, inability to concentrate, loss of interest, sexuality issues I have had RLS for more than 40 yrs. It was well controlled with Sinimet with few side effects. In Spring of 08 I underwent a complete hysterectomy and the Sinimet quite working within hours. The doctor doubled the dose, then tripled the dose and I was still miserable. I would pace for hours, the RLS went into my hands and arms, I cried for hours on end. I was switched to Requip .25 three times a day. That helped a little so it was doubled to .25 six times a day. I now have control of the RLS about 60% of the time. Between the RLS and Requip I feel as if my life is ruined. Either the side effects are bothering me or the RLS is. It controls my life. I have to plan around it all the time. Some nights I get little sleep, I need to allow extra time for driving because I either stop to pace or start feeling sleepy and stop to get awake, I have to plan where to sit in meetings because I have to get up because of the RLS or feeling sleepy. The depression is very bad. I sometimes cry for hours on end. The anger and anxiety are bad. But I don't know what to do. I can't live with the RLS as is and I can't seem to get anymore relief with anything else. This is ruining both my professional and personal life. My doctor gets impatient with me and doesn't seem to have any other answer, I've been to a psychologist who grew impatient with me because I woulnd't make any imporvements in my life, and he was supposed to be a specialist in depression. I would love to have some F 58
5/20/2009
 3   Daytime sleepiness, severe leg and foot pain,ringing in the ears, hyper interest in sex but difficuly with erection, hyper sensation in the early evening (extreme nervousness}, mild tingling in the hands, leg and foot swelling. It's a catch 22...Can't sleep without it and endure the side effects. M 65 2 years
5/17/2009
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 5  RLS This is an update to a post I made a couple of years ago. I've been on Requip almost five years now. Here's what I experience now: 1. My daily dose has been stable now for almost two years. .5 about 1pm, .5 around 11pm and another 1mg just before I go to bed. The 1pm dose stops the rebound effect which I only get when I forget to take the afternoon dose. 2. I continue to experience increased libido but for the past year ,decreased sensitivity. Could the the decreased senstivity may be due to age? Its similar to useing a condom. 3. I've almost forgoten that I have RLS. I never wake up in the middle of the night anymore. I now use a generic brand (Ropinirole) and find it works faster. It may be my imagination, but if I let it disolve in my mouth it kicks in much faster. That didn't happen with the brand name version. This generic brand is more disolvable then the brand name. I prefer it now. Has anyone used the Requip Extended Release? I'm very pleased with Ropinirole. I would reccomend it to anyone, but you gotta give it time! I would tell anyone considering it, to give it at least a year to find the more or less effetive dose for you. IT may take even longer for the perfect dose for your individual need. Ask your doctor to have the pharmacist give it to you in .05mg tabs with an order to take something like 2mg daily as needed. You can adjust your dose more easily with the smaller tabs. M 68 5 years
5/11/2009
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 1  RLS Premature Atrial Contractions, Shortness of Breath, Forgetfulness, Confusion, General Weakness, Chronic Pharyngitis, Post Nasal Drainage, Anxiety, Low Back Pain, Fatigue, Weight Gain, mild paranoia. I have been on Requip for about 1yr. I also have Bipolar Disorder and am on Meds for it. My Psychiatrist prescribed and didn't give me any info or tell me anything to watch out for. This is a horrible and dangerous drug and needs to be taken off the market. If there are any class action suits relating to this drug I would like to know about them. F 62 1 years
4/27/2009
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 3  severe RLS weight gain, nausea, sleepiness during the day I take 4mg of Requip daily. A specialist said he had seen only a handful of people whose RLS is as bad as mine. I fall asleep during the day, and evening. Then when I go to bed, I sleep almost exactly an hour and a half, then I'm up for the rest of the night most nights. Then after only 2 hours' sleep for several nights in a row, I crash and sleep about 6 hours maybe one night in 4 or 5 nights. When I have an early morning appointment after one of these 2-hour nights, it's like driving drunk. This is no way to live. F 67 3 years
4/22/2009
 1  RLS I experienced weight gain, hyposexual activity with my wife, hypersexuality on internet. Yes, it stopped the RLS (1mg taken at night) Caused a separation, with me not knowing why this happened. Saw an ad on tv about Requip lawsuit dealing with the gambling, which I did online but with 'play' money. I googled requip and started to cry. everything that was ruining my life and had no idea why was answered. I stopped cold turkey, have began to lose weight, have no desire to do things on the internet and am trying to regain the trust I lost from my wife (yes, still separated). Am attending sessions with a psychologist all out of my own pocket. I am not being accepted into the lawsuit because this drug did not cause me any losses in gambling debt. I feel that I lost more than money, I lost my wife's trust. I wouldn't recommend this life ruining drug to my worst enemy! DONT USE IT!!!! M 50 1.5 years
3/29/2009
 3  PLM nausea, viral illness? Helps me feel more awake during the day! However, side effects may be outweighing benefits: have been experiencing mild bouts of nausea in the evenings. Sometimes wake up in the middle of the night feeling nauseous or else very shaky. Only threw up once, while increasing the dose, but have had 'choking' feelings and hypersalivating. Every time I've increased the dose I've gotten a viral illness: coincidence? Don't know, there's a lot of stuff going around this time of year and family members have had it too. Will give it a while longer, but talk to doc if nausea doesn't improve. F 24 3 weeks
3/26/2009
 1  RLS Constant feeling I was about to throw-up. Strange headache that seemed to originate a few inches behind and between my eyes. Anxiety. And I only took it once, then refused any more. Everything horrid of what others wrote about this stuff was true. IF it helps someone out there, I am thankful and amazed. While it did make me sleepy and there were no RLS symptoms that night, I would much prefer RLS to this nightmare. M 52 1 days
3/25/2009
 3  rls zombie like fatigue, mild stomache ache/ feeling sick,severe dihorea, mouth ulcers/coldsores, (feeling run down) anxious, nervousness, paranoid, mood swingy/depressive like symptoms. very thirsty/dry mouth, itchy feet, watery blurred eyes. mild pain in ball foot and knees (apart from that no RLS ha !!) relived my RLS within 2 days . i wake feeling unrefreshed hungover with puffy eyes. they give me an unerving grounded/spaced out feeling (i'm normally hyper maybe there relaxing me & i'm not used to it) i normally have arthritis in neck & carpal tunnel: these symptoms have improved since being on adartrel. the symptoms outway the side affects by far. doc recons i'll be off them in 3 months. been on them 5 wks now there starting to be less afective i can't bear to up the dose only on 2 tabs a night, i'll try last the 3mnth i wouldn't like to be on them permanently there too distrubtive to everyday life. F 41 5 weeks
3/7/2009
 2  RLS Increased, and obnoxious, sexuality starting day 7. I took the starter pack for 8 days, with the final day at the full 1 mg dose. No improvement in my ability to sleep--I wake up every 2 hours. I am quitting this medication, and will try exercise and relaxation techniques. F 51 8 days
2/27/2009
 2  RLS I am a 19 year old college student diagnosed with rls and prescribed requip. I started to experience some very strange side effects from the drug that seemed to baffle people. After reading this post I realized I was not alone. I started to have tingling sensations in my head and felt my temples pulsating. I always took it before bed time as prescribed and I would go to sleep nasally congested from it. I had this very foggy head the next day and was not able to concentrate. You can pretty much say it gave me a pretty short attention span. Either way it didnt completely take away my rls sensations. It seemed to replace it with vibrating sensations in my feet. M
2/23/2009
 1  PLMD Facial swelling including: eyes, lips, nose & tongue. Level-10 headache upon waking. This was my first dose of .5mg. I would NEVER take it again! F 34 1 days
2/1/2009
 3  RLS Sometimes it works...sometimes not. Sometimes it makes me down-right "antsy". Has anyone experienced any weight gain while taking this medication? If you have...pleas e-mail me and share your experience with me. Thanks! F 47 2 years
1/29/2009
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 1  rls / plmd I was on requip for a year and a half. What started as a Miracle, ended in a trip to one of the lower levels of Hell. I tolerated every side effect by rationalizing " Well, you weigh the bad with the good ...and I can sleep, so...." I was put on requip because I went to a dr for snoring and what my husband thought was sleep apnea - he thought I jerked back from interupted breathing...and I was suffering severe sleep deprivation. I had a sleep study / was Dx with rls and plmd. My prescribing physician kept saying you need to up the dose to combat the rebound and then the dose had to be increased again, due to augmentation. I ended up taking requip all day long - .25, then .50 mgs every four hours...then 1 and 2 mgs at night. If I didn't, my legs and arms had myoclonic jerks as if I had parkinson's --- I had to stand at meetings and was asked in hushed tones if I had parkinson's. I was more and more anxious about the time of day -- like a drug addict, because if I missed a dose < I fell asleep at my desk / driving too. By the grace of God, I'm not dead from an MVA. I sometimes had to pull over to doze off on my way to work ! > Ankles too stiff in the morning to walk < I hobbled out of bed > , fingers, especially thumbs, wrists too stiff to pick up a coffee pot, add depression < I never had before > irritable < becasue I was always so sleepy> , and finally, add incontinence!!- urine just ran out of me when I stood up or moved - even when my bladder wasn't full > at this point, I went off the drug cold turkey ! DON"T TAKE THIS DRUG UNLESS YOU HAVE TRIED EVERYTHING ELSE AND IT'S LIFE OR DEATH - This drug, in my opinion, is poison to your body. I used codeine at night for five days to get through withdrawal. I noticed most of the side effects were gone by day two...no more stiffness in ankles, thumbs, wrists... I was awake !, not drowsy !!...and no more myoclonic jerks and rls during the day or evening. My legs didn't start to F 49 1.5 years
1/26/2009
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 4  parkinsons big weight gain . Very sleepy after second dose. cant sleep very well at night.edema in legs and hands. acid reflux after taking second dose.balance is off a little. dry mouth which in turn has caused bad teeth. bad cough I am still taking requip 5 mg 3 times aday I guess it helps some F 64 6 years
1/22/2009
 1  Restless Leg Syndrome 1. Terrible augmentation; 2. Acute bronchitis twice in a 6 week period (no cold or flu preceding either); 3. Horrible heartburn; and 4. Compulsive overeating. While it did help me sleep in the beginning, the augmentation started within a couple of weeks (only took .5mg at night, then .75, the 1.0 to get results). RLS symptoms started showing up earlier and earlier in the day. Also, the compulsive overeating was extremely disturbing, not to mention two bouts, out of nowhere, of acute bronchitis. Will go back to half a xanax and also add Folic acid each morning (recommended by the RD at our local health food store). Definitely not worth the side effects!!! F 49 4 months
1/20/2009
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 2  RLS Godsend at first...after several months, developed nausea, vomiting, nasal congestion (with 5 minutes of taking a pill), headaches, extreme drowsiness. Question: Has anyone experienced side effects coming off the requip...i.e, quitting cold turkey. F 63 7 years
1/15/2009
 4  RLS I had most of what other people discribe, and some specific to me. One major one was constant very bad gagging post nasal drip. This has now "almost" stopped since going off drug. I posted before in Oct. I began to tell about acidentally discovering that common table salt (salt water)seems to control the RLS at night. Since Oct. I have seen my doc and told him about going off the drug. Told him about the salt thing. I have high B P I take meds for. Doc didn't discourage the salt. He wonders if it is the sodium, the iodin, or the cloride. Salt has continued to work for me since late June of 08. Had to find right amount desolved in water by experiment. It works for me 99% of nights. worth a try I'd say. Doc said to bad it's a common element, or I could make a fourtune on this discovery. M 63 18 months
1/9/2009
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 5  RLS I'm 67. Have been taking reqip for about three years now. Have a few side effects. Hypersexuality, flashes in eyes, weight gain. I can live with these. My only real complaint about it is the rebound effect about halfway thru the next day. I take a total of 2mg. in three divided doses so that I have a blood level all the time. I would like to know if anyone has tried the Requip XL (long acting Requip) I just found out about it today. M 67 3 years
1/4/2009

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