REQUIP Reviews (ROPINIROLE HYDROCHLORIDE)

Average Rating: 2.8 (379 Ratings)

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 CNS, MISCELLANEOUS

 Type: Rx Drug

  

REQUIP  (ROPINIROLE HYDROCHLORIDE):  This medication is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). Ropinirole is also used to treat restless legs syndrome (RLS). It may improve your sleep by decreasing the urge to move your legs and decreasing uncomfortable/unpleasant feelings in the legs. This medication works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-09-19 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR REQUIPCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  RLS Sleepiness, mild nausea that went away, blurred vision, hard to lose weight, fatigue At first, the RLS was well controlled on a low dose. Now the dose has more than doubled, but the RLS has actually gotten much worse. It now hits morning, noon, and night, and is strong enough to force me awake even though I am so sleepy from the Requip, seizure med, and Ambien that I am stumbling in a stupor feeling as though I will drop unconscious any moment, yet I am attacked any moment I sit or lie down. I am so miserable. I am also in remission from a rare leukemia, have a brain tumor/lesion, high blood pressure, asthma, allergies, hypothyroidism, and now possible lupus. Suffice to say I do not feel well. A sleep study showed my oxygen level at 78% during sleep. A neurological test called VEP showed optic neuritis (inflammation/demyelination) of the back of both optic nerves. Don't know if my blurry vision is due to lupus, MS, brain scarring, medication like Requip, or just dry eye. The vision problem is like the kind of blur you get if you were looking into a cold wind and your e F 52 1 years
2/24/2007
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 3  nightime leg cramps nausea, vomiting, pain behind left eye Had taken quinine for leg cramps, but insurance will no longer cover. Doctor said , try requip. Helped reduse leg cramps by day 4. Nausia worse on day 4. Day 6 , major headache behind left eye. F 61 6 days
2/20/2007
 4  RLS 1 mg at bedtime really helped my sleep at night but seemed to bring on more symptoms from say 5 pm on. If I take it 1 mg at 5pm and 1 mg at bedtime relieves the RLS completely. But during the day just so tired all day and if I take the 5 pm dose very difficult to stay awake and that is when I do the most work (transcription). Also just diagnosed with fibromyalgia and went off the Requip to try Flexeril at night. Felt great for about a week then the RLS came back and makes me fairly dsyfunctional. Just frustrated and confused what direction to go in. Need to be wake during the day and sleep at night, please. Also weight gain of 10 pounds, dieting hasn't helped. F 52 3 months
2/15/2007
 4  RLS I have been taking Requip for 8 weeks. Started with .25 and for the last 6 weeks I'm at 1mg. I must say, I am very pleased overall with the cesation of my leg cramps, which I suffered with for the past several years. I am having some augmentation problems. I went to my eye doctor today with a complaint of eye fatigue and some slight peripheral vision problems. Turns out I have nystagmus, which is a condition marked by uncontrollable eye movements. With me it is very slight but noticeable, especially when driving. Not enough to be dangerous, but enough where I wouldn't drive for more than 1 hour at a time at this point. So, here is a new side effect NYSTAGMUS. Never saw this particular problem noted by anyone. Anyone else? M 59 8 weeks
2/12/2007
 4  RLS I have experienced some nausea since beginning Requip but have not been sure if it or the Metforman I take was causing the problem. A symptom that bothers me more is that I seem to be chewing the inside of my mouth and moving my tongue against my teeth without realizing it. The inside of my mouth has developed ridges from being chewed and the tip of my tongue feels raw at night. I have not read any other comments about this symptom, Has anyone else experienced this? F 59 6 weeks
2/9/2007
 1  RLS Since starting the RLS got a hundred times worse. Had to keep increasing dose, up to 3 mg. Once the drug wears off RLS bothers me all the time, used to only bother me at night. Trying to get off, skipped dose one night and thought I was going to die, so much pain, jerking, anxiety. Titrating down over 2 weeks and takin Clonipan to help. I would not reccommend this drug for anyone. When it wears off the pain is more intense and constant because of the rebound effect of the dopamine receptors. F 47 30 days
2/7/2007
 2  RLS Significant increase in symptoms late afternoon and evening Side effects so severe I had great difficulty driving home from work without stopping along the way to try to get relief. F 46 1 months
1/24/2007
 2  RLS I started with the two week trial pack, and after increasing dosage I spent one night with nausea and vomiting. I experienced dizziness. I also began to have RLS symptoms during the day everyday. I quit after I finished the trial pack and spent several days and nights with increased RLS without rest. I guess this is the rebound effect, and was very unpleasant. It was worse then I had before I started the requip. I will not take this medication. F 44 2 days
1/18/2007
 2  rls NAUSEA oh it's horrible! I have to fall asleep before it sets in or I get so sick. I thought it helped at first, but after almost a year, I get sicker and sicker the longer I take it. have cut back to 1mg. every other night if I can, I just can't take the nausea. Plus it totally knocks me out. I have a young son and just can't wake up if he calls. This med does nothing for day spams. M 37 1 years
1/9/2007
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 4  RLS In the beginning my doctor tried to take me off Klonopin and start the Requip. What a mistake, I had every side effect known to man, but I think part of it was withdrawal from the Klonopin. Since then I now take Klonopin and 2 mg Requip every night. The requip alone wasn't helping my symptoms. What I find interesting is the comment I read about experiencing rectal cramps. I thought I had something seriously wrong with me. Works great in combination with Klonopin. F 47 9 months
1/5/2007
 4  RLS Other than increased RLS symptoms a couple of hours before I take the pill at bedtime and fatigue off and on, it does help with twitching and leg cramps. However, anyone else losing their hair? My normally very healthy hair is breaking and falling out! F 60 4 months
1/4/2007
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 3  RLS Acid reflux in the middle of the night; RLS is worse in the afternoons; weight gain; excessive puffiness around the eyes; increased depression; vivd dreams; light-headedness; anxiety; breathless or smothering feeling.. The RLS is hardly noticeable at night, but I wake-up in the middle of the night feeling anxious, probably as the result of some horrendous dream. F 57 45 days
1/4/2007
 3  RLS At 4mg. I get drowsy and nauseated within 45 mins of taking it. Initially I also developed a very strong and persistent erection (without any stimulation) that demanded use or would be painfully persistent for 45-60 minutes. This side effect gradually lessened over about 9 months to the point today where it causes some arousal which I can use to advantage or ignore with relative ease. I have also noted that if I forget and have any wine within hours of taking the Requip, the RLS is actually worsened. The 4 mg.dose wears off like clockwork in exactly 4 hours. A second dose when the first wears off works without the aforementioned side-effects. M 58 9 months
1/1/2007
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 1  RLS Extreme pain in hand and finger joints and tendons and in knee, leg, ankle and feet tendons. Depression, increased appetite and subsequent weight gain, particularly around midsection. I posted a response to a Requip sample packet (14 pills) for RLS three months ago. Experiencing immediate severe hand and finger pain, I discontinued the pills. It has now been three months since taking them and I fear my body has been permanently altered... Now also have severe pain in my knees, shins and Achilles tendons. Also signifigant weight gain around my midsection and constant depression... Talked with three drs., the last a Rheumatologist, who prescribed occupational hand therapy, which made the pain worse, even after wearing a wrist splint for 4 weeks. Guess I am just one of the unlucky ones who reacted badly to the drug.... but beware... the RLS relief hardly worth the possible side effects... Has anyone successfully had bad side effects disappear with discontinued use of this med? F 70 14 days
1/1/2007
 3  restless legs I had no side effects building up to 1mg. However when I tried to stay at that dose, the nausea was too much. Also having some vision issues, seeing flashing lights, as if a police car with white lights is parked outside my windows. Not sure if the side effects are worth it. F 45
12/31/2006
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 3  PLMD None noticed, except for difficulty /mainting or losing weight Have never felt any noticeable effects of periodic limb movement disorder, although diagnosed with elevated index during 3 sleep studies. and am taking Requip at 2 mg per day for 1 year. Am wondering if I can wean off Requip safely and how to do it? F 63 13 months
12/27/2006
 2  RLS Bloodshot eyes, nausea, headache Did not help with RLS F 20
12/22/2006
 3  RLS Upper GI issues; vertigo; mild headache; symptoms earlier in the day; markedly increased nighttime libido. Seems to work on nighttime RLS, but unsure whether dealing with the side effects are worth it. M 42 1 months
12/15/2006
 5  RLS Drowsy within 30 minutes of taking. More frequent early evening episodes of RLS. It is wonderful to be able to sleep at night. I have had RLS since a small child and am now able to sleep the entire night. If I take 1 mg of Requip at 8:30, I am able to sleep by 9:30 and stay asleep until the alarm goes off. There had been no relief for the RLS prior to Requip. F 51 3 months
12/12/2006
 4  RLS I have had RLS most of my life. I had taken Sinimet (Parkinsons med) for my RLS but caused severe RLS problems durring the day. I have been taking Requip for about 6 weeks and have noticed the same problems. When I go to bed, I take 1mg of Requip and awake about 4 hours later with both of my hands asleep and am unable to get back to sleep. This then results in fairly severe arthritic pain in my hands and fingers for the rest of the night and the next day. But no nausia, seems to help greatly with my RLS pain and involentary movement M 41 6 weeks
12/1/2006
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